Lipid metabolism in Alzheimer’s disease
Abstract
Since the metabolic disorder may be the high risk that contribute to the progress of Alzheimer's disease (AD). Overtaken of High-fat, high-glucose or high-cholesterol diet may hasten the incidence of AD in later life, due to the metabolic dysfunction. But the metabolism of lipid in brain and the exact effect of lipid to brain or to the AD's pathological remain controversial. Here we summarize correlates of lipid metabolism and AD to provide more foundation for the daily nursing of AD sensitive patients.
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Dietary intervention represents a fairly straightforward manner to achieve proper lipid homeostasis.
“Lipids provide a further advantage in that dietary intervention represents a fairly straightforward manner to achieve proper lipid homeostasis [111,112,113].”
From Alzheimer's Disease: Treatment Strategies and Their Limitations. (2022) · cites this paper as [112]
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Alzheimer's Disease: Treatment Strategies and Their Limitations.
Passeri, E., Elkhoury, K., Morsink, M., Broersen, K., Linder, M., Tamayol, A., Malaplate, C., Yen, F. T., & Arab-Tehrany, E. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232213954 · Cited by 592 · see citing works
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- Authors
- Zhu, T.-B., Zhang, Z., Luo, P., Wang, S.-S., Peng, Y., Chu, S.-F., & Chen, N.-H.
- Affiliations
- Hunan University of Traditional Chinese Medicine (CN)
- Corresponding author
- Chen, Nai-Hong
- Venue
- Brain Research Bulletin
- Publisher
- Elsevier BV
- Published
- 2019-01
- Volume
- 144
- Pages
- 68-74
- ISSN
- 0361-9230 (ISSN-L)
- OpenAlex
- W2901221619
- Cited by
- 55
- References
- 12
- Citations by year
- 2026: 4 · 2025: 6 · 2024: 5 · 2023: 7 · 2022: 17 · 2021: 9 · 2020: 5 · 2019: 2
- FWCI
- 0.53
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Brain Research Bulletin (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Natural Science Foundation of China (81603316, 81473375, 81603315)
- CAMS Innovation Fund for Medical Sciences (CIFMS) (2016-I2M-1-004)
- Beijing Key Laboratory of New Drug Mechanisms and Pharmacological Evaluation Study (BZ0150)
- Topics
- Health Sciences › Medicine › Physiology › Alzheimer's disease research and treatments
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Health Sciences › Nursing › Nutrition and Dietetics › Fatty Acid Research and Health
- Keywords
- Alzheimer's disease, lipid metabolism, brain lipid metabolism, high-fat diet, high-glucose diet, high-cholesterol diet, metabolic dysfunction
- MeSH terms
- Adipose Tissue, Alzheimer Disease, Brain, Diet, Humans, Lipid Metabolism, Adipokines, Mesenchymal Stem Cells
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