The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
A review of low-intensity focused ultrasound pulsation
Open accessAbstract
With the recent approval by the Food and Drug Administration (FDA) of Deep Brain Stimulation (DBS) for Parkinson's Disease, dystonia and obsessive compulsive disorder (OCD), vagus nerve stimulation (VNS) for epilepsy and depression, and repetitive transcranial magnetic stimulation (rTMS) for the treatment of depression, neuromodulation has become increasingly relevant to clinical research. However, these techniques have significant drawbacks (eg, lack of special specificity and depth for the rTMS, and invasiveness and cumbersome maintenance for DBS). This article reviews the background, rationale, and pilot studies to date, using a new brain stimulation method-low-intensity focused ultrasound pulsation (LIFUP). The ability of ultrasound to be focused noninvasively through the skull anywhere within the brain, together with concurrent imaging (ie, functional magnetic resonance imaging [fMRI]) techniques, may create a role for research and clinical use of LIFUP. This technique is still in preclinical testing and needs to be assessed thoroughly before being advanced to clinical trials. In this study, we review over 50 years of research data on the use of focused ultrasound (FUS) in neuronal tissue and live brain, and propose novel applications of this noninvasive neuromodulation method.
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Cites
Treatment of depression with transcranial direct current stimulation (tDCS): A Review
Nitsche, M. A., Boggio, P. S., Fregni, F., & Pascual-Leone, A. (2009) · Experimental Neurology · doi:10.1016/j.expneurol.2009.03.038 · Cited by 498
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A tractography analysis of two deep brain stimulation white matter targets for depression
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In vitro effects of ultrasound with different energies on the conduction properties of neural tissue
Tsui, P.-H., Wang, S.-H., & Huang, C.-C. (2005) · Ultrasonics · doi:10.1016/j.ultras.2004.12.003 · Cited by 149
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Cited by
Image-Guided Transcranial Focused Ultrasound Stimulates Human Primary Somatosensory Cortex
Lee, W., Kim, H., Jung, Y., Song, I.-U., Chung, Y. A., & Yoo, S.-S. (2015) · Scientific Reports · doi:10.1038/srep08743 · Cited by 414
Self-citationFox, M. D., Halko, M. A., Eldaief, M. C., & Pascual-Leone, A. (2012) · NeuroImage · doi:10.1016/j.neuroimage.2012.03.035 · Cited by 395
Transcranial Ultrasound (TUS) Effects on Mental States: A Pilot Study
Hameroff, S., Trakas, M., Duffield, C., Annabi, E., Gerace, M. B., Boyle, P., Lucas, A., Amos, Q., Buadu, A., & Badal, J. J. (2013) · Brain stimulation · doi:10.1016/j.brs.2012.05.002 · Cited by 248
Focused ultrasound for neuromodulation
Darrow, D. P. (2019) · Neurotherapeutics · doi:10.1007/s13311-018-00691-3 · Cited by 190
Lee, J.-H., Cho, I.-J., Ko, K., Yoon, E.-S., Park, H.-H., & Kim, T. S. (2017) · Microsystem Technologies · doi:10.1007/s00542-016-2912-5 · Cited by 68
Metadata
- Authors
- Bystritsky, A., Korb, A. S., Douglas, P. K., Cohen, M. S., Melega, W. P., Mulgaonkar, A. P., DeSalles, A., Min, B.-K., & Yoo, S.-S.
- Venue
- Brain Stimulation
- Publisher
- Elsevier BV
- Published
- 2011-07
- Volume
- 4
- Issue
- 3
- Pages
- 125-136
- ISSN
- 1876-4754 (ISSN-L)
- 1935-861X
- OpenAlex
- W2068126292
- Cited by
- 409
- References
- 5
- FWCI
- 7.11
- Type
- journal article
- Language
- en
- Open access
- green
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- Bystritsky, A., Korb, A. S., Douglas, P. K., Cohen, M. S., Melega, W. P., Mulgaonkar, A. P., DeSalles, A., Min, B.-K., & Yoo, S.-S. (2011). A review of low-intensity focused ultrasound pulsation. Brain Stimulation. https://doi.org/10.1016/j.brs.2011.03.007
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