The DOI matches its Crossref record; 110 of the 110 references it cites were found in a registry or an index.
Antioxidant, antiradical, and antimicrobial activities of polysaccharides obtained by microwave-assisted extraction method: A review
Abstract
The antioxidant and antimicrobial activities of polysaccharides extracted by microwave-assisted extraction (MAE) were reviewed. An ascending dose-dependent manner was found for the in vitro antioxidant (e.g., nitrite scavenging, phospho-molybdenum reduction, inhibition of lipid peroxidation (ILP), ferric reducing power, and ferrous metal ions chelating), and antiradical (against DPPH, OH, ABTS, NO, and O 2 - ) activities. There was a positive and significant correlation between ILP and erythrocyte hemolysis inhibition, showing the excellent antioxidative properties to prevent the risk of cell damage. These carbohydrate-based polymers in vivo could reduce malonaldehyde and protein carbonyls and increase stress-resistance-related enzymes such as catalase, superoxide dismutase, and glutathione peroxidase. They showed an effective bactericidal activity against a wide variety of gram-negative and gram-positive bacterial infections. The in vitro strong antifungal and antiviral activities of sulfated polysaccharides extracted by MAE were also diagnosed without any cytotoxicity effect. Therefore, these biomacromolecules might be used to develop functional foods and nutraceuticals.
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“MAE combined with RSM has several advantages compared with other advanced extraction technologies, such as higher extraction yield, improved selectivity, better handling, and low solvent consumption [12].”
From Optimized microwave-assisted azadirachtin extraction using response surface methodology (2024) · cites this paper as [12]
Citations
Cites
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Wang, J., Hu, S., Nie, S., Yu, Q., & Xie, M. (2015) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2016/5692852 · Cited by 727
Microwave-assisted extraction of sulfated polysaccharides (fucoidan) from brown seaweed
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A critical review on production of biopolymers from algae biomass and their applications
Kartik, A., Akhil, D., Lakshmi, D., Gopinath, K. P., Arun, J., Sivaramakrishnan, R., & Pugazhendhi, A. (2021) · Bioresource Technology · doi:10.1016/j.biortech.2021.124868 · Cited by 212
Metadata
- Authors
- Mirzadeh, M., Arianejad, M. R., & Khedmat, L.
- Affiliations
- Qazvin University of Medical Sciences (IR)
- Tabriz University of Medical Sciences (IR)
- Baqiyatallah University of Medical Sciences (IR)
- Corresponding author
- Khedmat, Leila
- Venue
- Carbohydrate Polymers
- Publisher
- Elsevier BV
- Published
- 2020-02
- Volume
- 229
- Pages
- 115421
- ISSN
- 0144-8617 (ISSN-L)
- OpenAlex
- W2979284845
- Cited by
- 337
- References
- 110
- Citations by year
- 2026: 37 · 2025: 72 · 2024: 56 · 2023: 41 · 2022: 58 · 2021: 47 · 2020: 26
- FWCI
- 2.95
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Carbohydrate Polymers (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Polysaccharides Composition and Applications
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
- Health Sciences › Medicine › Pharmacology (medical) › Fungal Biology and Applications
- Keywords
- polysaccharides, microwave-assisted extraction, antioxidant activity, free radical scavenging, antimicrobial activity, lipid peroxidation inhibition, erythrocyte hemolysis, oxidative stress enzymes, sulfated polysaccharides, antifungal activity, antiviral activity, functional foods, nutraceuticals
- MeSH terms
- Animals, Anti-Infective Agents, Antioxidants, Humans, Microwaves, Polysaccharides
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