Cited by 371Seaweed-derived Bioactive CompoundsPolysaccharides Composition and ApplicationsMarine and coastal plant biology

Microwave assisted extraction of sulfated polysaccharides (fucoidan) from Ascophyllum nodosum and its antioxidant activity

Yuan, Yuan, Macquarrie, Duncan·2015·Carbohydrate Polymers

Abstract

Sulfated polysaccharides (fucoidan) from brown seaweed Ascophyllum nodosum were extracted by microwave assisted extraction (MAE) technology. Different conditions of temperature (90-150°C), extraction time (5-30 min) were evaluated and optimal fucoidan yield was 16.08%, obtained from 120°C for 15 min's extraction. Compositional analysis, GPC, HPAEC and IR analysis were employed for characterization of extracted sulfated polysaccharides. Fucose was the main monosaccharide of fucoidan extracted at 90°C while glucuronic acid was the main monosaccharide of fucoidan extracted at 150°C. Both the molecular weight and sulfate content of extracted fucoidan increased with decreasing extraction temperature. All fucoidans exhibited antioxidant activities as measured by DPPH scavenging and reducing power, among which fucoidan extracted at 90°C was highest. This study shows that MAE is an efficient technology to extract sulfated polysaccharides from seaweed and Ascophyllum nodosum could potentially be a resource for natural antioxidants.

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Crossref · 10.1016/j.carbpol.2015.04.057

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Authors
Yuan, Y., & Macquarrie, D.
Affiliations
University of York (GB)
Corresponding author
Macquarrie, Duncan
Venue
Carbohydrate Polymers
Publisher
Elsevier BV
Published
2015-09
Volume
129
Pages
101-107
ISSN
0144-8617 (ISSN-L)
OpenAlex
W317714569
Cited by
371
References
50
Citations by year
2026: 23 · 2025: 45 · 2024: 39 · 2023: 43 · 2022: 35 · 2021: 44 · 2020: 36 · 2019: 31 · 2018: 25 · 2017: 25 · 2016: 16 · 2015: 9
FWCI
38.85
Type
journal article
Language
en
Open access
closed
Locations
  • Carbohydrate Polymers (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Polysaccharides Composition and Applications
  • Physical Sciences › Earth and Planetary Sciences › Oceanography › Marine and coastal plant biology
Keywords
fucoidan, sulfated polysaccharides, Ascophyllum nodosum, brown algae, microwave-assisted extraction, extraction temperature, extraction time, fucose, glucuronic acid, sulfate content, molecular weight, antioxidant activity, DPPH radical scavenging, reducing power, natural antioxidants
MeSH terms
Antioxidants, Biphenyl Compounds, Carbohydrates, Microwaves, Oxidation-Reduction, Picrates, Polysaccharides, Temperature, Time Factors, Uronic Acids, Free Radical Scavengers, Ascophyllum

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