Preparation of different molecular weight polysaccharides from Porphyridium cruentum and their antioxidant activities
Abstract
Hermetical microwave was used to degrade Porphyridium cruentum polysaccharides from 2918 to 256.2, 60.66 and 6.55kDa. The antioxidant properties of different molecular weight polysaccharides were evaluated by determining the scavenging ability of free radicals, inhibitory effects on lipid peroxidation in liver homogenates and hemolysis of mouse erythrocytes. Analysis of physicochemical properties confirmed that microwave degradation might not markedly change the chemical components of the polysaccharides. High-molecular-weight polysaccharides from P. cruentum had no obvious antioxidant activity, but low-molecular-weight fragments after degradation exerted an inhibitory effect on oxidative damage. The 6.55-kDa fragment had stronger antioxidant activity than the 60.66 and 256-kDa fragments.
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The main non-enzymatic hydrolytic techniques used at an industrial level are ultrasound, microwaves, free radicals, or diluted acids.
“the main non-enzymatic hydrolytic techniques used at an industrial level are ultrasound (in the case of carrageenans, agarose and xylan), microwaves (for hydrolysis of exopolysaccharides obtained from Porphyridium cruentum), use of free radicals (for fucoidan and algae galactan), or the application of diluted acids (for example, phosphoric acid) [124,125,126,127,128,129,130].”
From The Potential of Seaweeds as a Source of Functional Ingredients of Prebiotic and Antioxidant Value (2019) · cites this paper as [126]
Antioxidant activity was reported for polysaccharides from Porphiridium cruentum.
“Antioxidant activity was also reported for polysaccharides from Porphiridium cruentum [121].”
From Anticancer and Cancer Preventive Properties of Marine Polysaccharides: Some Results and Prospects (2013) · cites this paper as [121]
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- Authors
- Sun, L., Wang, C., Shi, Q., & Ma, C.
- Affiliations
- Yantai University (CN)
- Dalian University of Technology (CN)
- Corresponding author
- Wang, Changhai
- Venue
- International Journal of Biological Macromolecules
- Publisher
- Elsevier BV
- Published
- 2009-07
- Volume
- 45
- Issue
- 1
- Pages
- 42-47
- ISSN
- 0141-8130 (ISSN-L)
- OpenAlex
- W2037920204
- Cited by
- 338
- References
- 14
- Citations by year
- 2026: 6 · 2025: 19 · 2024: 25 · 2023: 38 · 2022: 25 · 2021: 36 · 2020: 22 · 2019: 34 · 2018: 21 · 2017: 14 · 2016: 18 · 2015: 18 · 2014: 14 · 2013: 14 · 2012: 10
- FWCI
- 17.11
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- International Journal of Biological Macromolecules (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Natural Science Foundation of Shandong Province
- Topics
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
- Life Sciences › Agricultural and Biological Sciences › Food Science › Polysaccharides Composition and Applications
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Polysaccharides and Plant Cell Walls
- Keywords
- Porphyridium cruentum, red algae polysaccharides, molecular weight reduction, antioxidant activity, free radical scavenging, lipid peroxidation inhibition, erythrocyte hemolysis, oxidative damage, low molecular weight polysaccharides
- MeSH terms
- Animals, Antioxidants, Erythrocytes, Free Radicals, Molecular Weight, Polysaccharides, Lipid Peroxidation, Porphyridium, Mice
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