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Development of Integrin-Facilitated Bispecific Aptamer Chimeras for Membrane Protein Degradation

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The complex interactions between the cellular and non-cellular components of the brain tumor microenvironmental landscape and their therapeutic implications

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Multifaceted collagen-DDR1 signaling in cancer

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Clostridium butyricum and its metabolite butyrate promote ferroptosis susceptibility in pancreatic ductal adenocarcinoma

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Strategies for Efficient Targeting of Tumor Collagen for Cancer Therapy

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TREM2 Depletion in Pancreatic Cancer Elicits Pathogenic Inflammation and Accelerates Tumor Progression via Enriching IL-1β+ Macrophages

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The Efficacy of Tumor Mutation Burden as a Biomarker of Response to Immune Checkpoint Inhibitors

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Collagenase-mediated extracellular matrix targeting for enhanced drug penetration and therapeutic efficacy in nanoscale delivery systems for cancer therapy

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The conundrum of breast cancer and microbiome - A comprehensive review of the current evidence

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Flourishing tumor organoids: History, emerging technology, and application

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Understanding the matrix: collagen modifications in tumors and their implications for immunotherapy

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Breaking the stromal barrier in pancreatic cancer: Advances and challenges

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Genetic Deletion of Galectin-3 Inhibits Pancreatic Cancer Progression and Enhances the Efficacy of Immunotherapy

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Unraveling the gut microbiome’s contribution to pancreatic ductal adenocarcinoma: mechanistic insights and therapeutic perspectives

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A Quick Guide to CAF Subtypes in Pancreatic Cancer

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Cirrhotic-extracellular matrix attenuates aPD-1 treatment response by initiating immunosuppressive neutrophil extracellular traps formation in hepatocellular carcinoma

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Lactate supports cell-autonomous ECM production to sustain metastatic behavior in prostate cancer

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Microbiome and pancreatic cancer: time to think about chemotherapy

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RGD-engineered nanoparticles as an innovative drug delivery system in cancer therapy

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Biological characteristics of pancreatic ductal adenocarcinoma: Initiation to malignancy, intracellular to extracellular

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Therapeutic Strategies to Overcome Fibrotic Barriers to Nanomedicine in the Pancreatic Tumor Microenvironment

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The microbiome and rise of early-onset cancers: knowledge gaps and research opportunities

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Inferring cell trajectories of spatial transcriptomics via optimal transport analysis

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Manipulating the gut and tumor microbiota for immune checkpoint inhibitor therapy: from dream to reality

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Integrating bulk and single-cell RNA sequencing data reveals the relationship between intratumor microbiome signature and host metabolic heterogeneity in breast cancer

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Reactivation of embryonic genetic programs in tissue regeneration and disease

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The Multifaced Role of Collagen in Cancer Development and Progression

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Intratumour microbiome of pancreatic cancer

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Exploring the role of the immune microenvironment in hepatocellular carcinoma: Implications for immunotherapy and drug resistance

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Novel roles for cooperating collagen receptor families in fibrotic niches

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Nanodrug-bacteria conjugates-mediated oncogenic collagen depletion enhances immune checkpoint blockade therapy against pancreatic cancer

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Exosomal integrins in tumor progression, treatment and clinical prediction (Review)

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Targeting Cellular Components of the Tumor Microenvironment in Solid Malignancies

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Single-cell and spatial transcriptomics reveal mechanisms of radioresistance and immune escape in recurrent nasopharyngeal carcinoma

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SLC35F2–SYVN1–TRIM59 axis critically regulates ferroptosis of pancreatic cancer cells by inhibiting endogenous p53

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KLF5 governs sphingolipid metabolism and barrier function of the skinPreprint

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Weighted gene coexpression network analysis and machine learning reveal oncogenome associated microbiome plays an important role in tumor immunity and prognosis in pan-cancer

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Oncogene-induced matrix reorganization controls CD8+ T cell function in the soft-tissue sarcoma microenvironment

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Intratumoral Microbiome: Foe or Friend in Reshaping the Tumor Microenvironment Landscape?

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ITGA3 promotes pancreatic cancer progression through HIF1α- and c-Myc-driven glycolysis in a collagen I-dependent autocrine manner

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Advances in Extracellular Matrix-Associated Diagnostics and Therapeutics

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Natural multi-osmolyte cocktails form deep eutectic systems of unprecedented complexity: discovery, affordances and perspectives

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Synthetic retinoid-mediated preconditioning of cancer-associated fibroblasts and macrophages improves cancer response to immune checkpoint blockade

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Collagen remodeling-mediated signaling pathways and their impact on tumor therapy

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Growth factor-triggered de-sialylation controls glycolipid-lectin-driven endocytosis

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Bioprinted Patient‐Derived Organoid Arrays Capture Intrinsic and Extrinsic Tumor Features for Advanced Personalized Medicine

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Targeting collagen to optimize cancer immunotherapy

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Insights into the relevance of targeting fibroblasts to control cancer

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Pancreatic ductal adenocarcinoma: tumor microenvironment and problems in the development of novel therapeutic strategies

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Profiling of Tumor Cell‐Delivered Exosome by Surface Enhanced Raman Spectroscopy‐Based Biosensor for Evaluation of Nasopharyngeal Cancer Radioresistance

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Recombinant humanized collagen type III with high antitumor activity inhibits breast cancer cells autophagy, proliferation, and migration through DDR1

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Loss of attachment promotes proline accumulation and excretion in cancer cells

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Bioengineering Approaches for the Pancreatic Tumor Organoids Research and Application

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A bioprinted sea-and-island multicellular model for dissecting human pancreatic tumor-stroma reciprocity and adaptive metabolism

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Glycosylation in the tumor immune response: the bitter side of sweetness

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Human Organoids and Their Application in Tumor Models, Disease Modeling, and Tissue Engineering

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Fibrotic Fortresses and Therapeutic Frontiers: Pancreatic Stellate Cells and the Extracellular Matrix in Pancreatic Cancer

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The extracellular matrix in inflammation and cancer

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New insights into the mechanisms of the extracellular matrix and its therapeutic potential in anaplastic thyroid carcinoma

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Acquired resistance to immunotherapy by physical barriers with cancer cell–expressing collagens in non–small cell lung cancer

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Targeting Oncogenic Wnt/β-Catenin Signaling in Adrenocortical Carcinoma Disrupts ECM Expression and Impairs Tumor Growth

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Targeting collagen in tumor extracellular matrix as a novel targeted strategy in cancer immunotherapy

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The war between the immune system and the tumor - using immune biomarkers as tracers

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HTRA1-driven detachment of type I collagen from endoplasmic reticulum contributes to myocardial fibrosis in dilated cardiomyopathy

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FBXO32 Stimulates Protein Synthesis to Drive Pancreatic Cancer Progression and Metastasis

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CREB3L1 facilitates pancreatic tumor progression and reprograms intratumoral tumor-associated macrophages to shape an immunotherapy-resistance microenvironment

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Halofuginone Disrupted Collagen Deposition via mTOR‐eIF2α‐ATF4 Axis to Enhance Chemosensitivity in Ovarian Cancer

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The type I collagen paradox in PDAC progression: microenvironmental protector turned tumor accomplice

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Emerging technologies and current challenges in intratumoral microbiota research

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COL12A1 Acts as a Novel Prognosis Biomarker and Activates Cancer-Associated Fibroblasts in Pancreatic Cancer through Bioinformatics and Experimental Validation

Song, Y. H., Wang, L., Wang, K., Lu, Y., & Zhou, P. (2023) · Cancers · doi:10.3390/cancers15051480 · Cited by 17 · see citing works

The effect mechanism of polysaccharides inhibit tumor immune escape: A review

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The Versatility of Collagen in Pharmacology: Targeting Collagen, Targeting with Collagen

Revert‐Ros, F., Ventura, I., Prieto-Ruiz, J. Á., Hernández‐Andreu, J. M., & Revert, F. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25126523 · Cited by 17 · see citing works

Refining the Treatment of Pancreatic Cancer From Big Data to Improved Individual Survival

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Integrative single‐cell sequencing analysis distinguishes survival‐associated cells from the breast cancer microenvironment

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The phase separation of extracellular matrix protein matrilin‐3 from cancer‐associated fibroblasts contributes to gastric cancer invasion

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The correlation between gut and intra-tumor microbiota and PDAC: Etiology, diagnostics and therapeutics

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Tumor Stroma as a Therapeutic Target for Pancreatic Ductal Adenocarcinoma

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Pharmacomicrobiomics in precision cancer therapy: bench to bedside

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Cross-Dataset Single-Cell Analysis Identifies Temporal Alterations in Cell Populations of Primary Pancreatic Tumor and Liver Metastasis

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Type X collagen knockdown inactivate ITGB1/PI3K/AKT to suppress chronic unpredictable mild stress-stimulated triple-negative breast cancer progression

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Tumor-Colonizing E. coli Expressing Both Collagenase and Hyaluronidase Enhances Therapeutic Efficacy of Gemcitabine in Pancreatic Cancer Models

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Type I collagen homotrimers: A potential cancer‐specific interventional target

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Untangling the tumorigenic role of homotrimeric collagen I

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Collagen I Homotrimers Promote PDAC Growth and Impact Immunity

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Abstract 4589: Deciphering collagen-responsive mechanism in pancreatic tumor progression and immunology at single-cell resolution

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Type I collagen deletion in αSMA+ myofibroblasts augments immune suppression and accelerates progression of pancreatic cancer

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