Sphingosine-1-Phosphate Links Persistent STAT3 Activation, Chronic Intestinal Inflammation, and Development of Colitis-Associated Cancer
Liang, Jie, Nagahashi, Masayuki, Kim, Eugene Y., Harikumar, Kuzhuvelil B., Yamada, Akimitsu, Huang, Wei-Ching, Hait, Nitai C., Allegood, Jeremy C., Price, Megan M., Avni, Dorit, Takabe, Kazuaki, Kordula, Tomasz, Milstien, Sheldon, Spiegel, Sarah·2013·Cancer Cell
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- Sphingosine-1-phosphate receptor 1 (S1PR1) expression in non-muscle invasive urothelial carcinoma: Association with poor clinical outcome and potential therapeutic targetHeounjeong Go, Pil-Jong Kim, Yoon Kyung Jeon, Yong Mee Cho, Kyungeun Kim, Bong-Hee Park, Ja Yoon Ku · 2015 · European Journal of Cancer
- Sphingosine kinase 1 is overexpressed and promotes adrenocortical carcinoma progressionYunze Xu, Baijun Dong, Jiwei Huang, Wen Kong, Wei Xue, Yu Zhu, Jin Zhang, Yong Huang · 2015 · Oncotarget
- Induction of Sphk1 activity in obese adipose tissue macrophages promotes survivalTanit L. Gabriel, Mina Mirzaian, Berend Hooibrink, Roelof Ottenhoff, Cindy P. A. A. van Roomen, Johannes M. F. G. Aerts, Marco van Eijk · 2017 · PLoS ONE
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- SPHK-2 Promotes the Particle-Induced Inflammation of RAW264.7 by Maintaining Consistent Expression of TNF-α and IL-6Guangpu Yang, Minghui Gu, Weishen Chen, Wenhua Liu, Yinbo Xiao, Haixing Wang, Weiming Lai, Guoyan Xian, Ziji Zhang, Ziqing Li et al. · 2018 · Inflammation
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- Exercise activates the hypothalamic S1PR1–STAT3 axis through the central action of interleukin 6 in miceVagner Ramon Rodrigues Silva, Thayana Oliveira Micheletti, Carlos K. Katashima, Luciene Lenhare, Joseane Morari, Alexandre Moura‐Assis, José Carlos de Lima Júnior, Juliana Alves de Camargo, Gabriela Reolon Passos, Rodrigo S. Gaspar et al. · 2018 · Journal of Cellular Physiology
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- The therapeutic effects of cycloastragenol in ulcerative colitis by modulating SphK/MIP‐1α/miR‐143 signallingAlaa Abdullah Bagalagel, Reem M. Diri, Ahmad Omar Noor, Deina Almasri, Hussain T. Bakhsh, Hussam Ibrahim Kutbi, Mohammed M.H. Al-Gayyar · 2022 · Basic & Clinical Pharmacology & Toxicology
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- Sphingosine kinase 1 knockout alleviates hepatic ischemia/reperfusion injury by attenuating inflammation and oxidative stress in miceGuang-Hui Qiang, Zhongxia Wang, Anlai Ji, Junyi Wu, Yin Cao, Guang Zhang, Yiyang Zhang, Chunping Jiang · 2019 · Hepatobiliary & pancreatic diseases international
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