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The building BLOC(k)s of lysosomes and related organelles

Dell’Angelica, Esteban C·2004·Current Opinion in Cell Biology
DOI 10.1016/j.ceb.2004.05.001
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Abstract

Hermansky-Pudlak syndrome defines a group of genetic disorders characterized by defects in organelles of the endosomal-lysosomal system, most notably melanosomes and platelet-dense granules. About a dozen genes have been implicated in the pathogenesis of the disease in humans and mice. Most of these genes encode novel polypeptides that are not conserved in unicellular eukaryotes. Recent studies have revealed that these polypeptides are stable components of at least three distinct, ubiquitously expressed protein complexes, named biogenesis of lysosome-related organelles complex (BLOC)-1, -2 and -3. These findings provide a framework for studies on the function of these proteins and the pathogenesis of Hermansky-Pudlak syndrome.

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  • Hps5 functions in the BLOC2 complex, which in melanophores is involved in transport from early endosomes to maturating melanosomes.

    “Hps5 functions in the BLOC2 complex, which in melanophores is involved in transport from early endosomes to maturating melanosomes (23, 43, 44, 85, 91).”

    From Lysosome-related organelles orchestrate guanine crystal formation in pigment cells (2026) · cites this paper as [43]

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Research works printed but not linked: 49

  1. Dell’Angelica, 2000, Lysosome-related organelles, FASEB J, 14, 1265
  2. Luzio, 2003, Membrane dynamics and the biogenesis of lysosomes, Mol Membr Biol, 20, 141, 10.1080/0968768031000089546 · DOI
  3. Mullins, 2001, The molecular machinery for lysosome biogenesis, Bioessays, 23, 333, 10.1002/bies.1048 · DOI
  4. Huizing, 2002, Hermansky-Pudlak syndrome: vesicle formation from yeast to man, Pigment Cell Res, 15, 405, 10.1034/j.1600-0749.2002.02074.x · DOI
  5. Suzuki, 2003, The mouse organellar biogenesis mutant buff results from a mutation in Vps33a, a homologue of yeast vps33 and Drosophila carnation, Proc Natl Acad Sci USA, 100, 1146, 10.1073/pnas.0237292100 · DOI
  6. Peterson, 2001, The Class C Vps complex functions at multiple stages of the vacuolar transport pathway, Traffic, 2, 476, 10.1034/j.1600-0854.2001.20705.x · DOI
  7. Sriram, 2003, deep-orange and carnation define distinct stages in late endosomal biogenesis in Drosophila melanogaster, J Cell Biol, 161, 593, 10.1083/jcb.200210166 · DOI
  8. Richardson, 2004, Mammalian late Vps orthologues participate in early endosomal fusion and interact with the cytoskeleton, Mol Biol Cell, 15, 1197, 10.1091/mbc.e03-06-0358 · DOI
  9. Falcón-Pérez, 2002, BLOC-1, a novel complex containing the pallidin and muted proteins involved in the biogenesis of melanosomes and platelet-dense granules, J Biol Chem, 277, 28191, 10.1074/jbc.M204011200 · DOI
  10. Moriyama, 2002, Pallidin is a component of a multi-protein complex involved in the biogenesis of lysosome-related organelles, Traffic, 3, 666, 10.1034/j.1600-0854.2002.30908.x · DOI
  11. Huang, 1999, The pallid gene encodes a novel, syntaxin 13-interacting protein involved in platelet storage pool deficiency, Nat Genet, 23, 329, 10.1038/15507 · DOI
  12. Zhang, 2002, The gene for the muted (mu) mouse, a model for Hermansky–Pudlak syndrome, defines a novel protein which regulates vesicle trafficking, Hum Mol Genet, 11, 697, 10.1093/hmg/11.6.697 · DOI
  13. Ciciotte, 2003, Cappuccino, a mouse model of Hermansky–Pudlak syndrome, encodes a novel protein that is part of the pallidin-muted complex (BLOC-1), Blood, 101, 4402, 10.1182/blood-2003-01-0020 · DOI
  14. Benson, 2001, Dysbindin, a novel coiled-coil-containing protein that interacts with the dystrobrevins in muscle and brain, J Biol Chem, 276, 24232, 10.1074/jbc.M010418200 · DOI
  15. Li, 2003, Hermansky-Pudlak syndrome type 7 (HPS-7) results from mutant dysbindin, a member of the biogenesis of lysosome-related organelles complex 1 (BLOC-1), Nat Genet, 35, 84, 10.1038/ng1229 · DOI
  16. Starcevic M, Dell’Angelica EC: Identification of snapin and three novel proteins (BLOS1, BLOS2 and BLOS3/reduced pigmentation) as subunits of biogenesis of lysosome-related organelles complex-1 (BLOC-1). J Biol Chem 2004, in press. · DOI
  17. Zhang, 2003, Ru2 and Ru encode mouse orthologs of the genes mutated in human Hermansky–Pudlak syndrome types 5 and 6, Nat Genet, 33, 145, 10.1038/ng1087 · DOI
  18. Di Pietro, 2004, Characterization of BLOC-2, a complex containing the Hermansky–Pudlak syndrome proteins HPS3, HPS5 and HPS6, Traffic, 5, 276, 10.1111/j.1600-0854.2004.0171.x · DOI · Paper page
  19. Gautam, 2004, The Hermansky-Pudlak syndrome 3 (cocoa) protein is a component of the biogenesis of lysosome-related organelles complex-2 (BLOC-2), J Biol Chem, 279, 12935, 10.1074/jbc.M311311200 · DOI
  20. Oh, 2000, The Hermansky–Pudlak syndrome (HPS) protein is part of a high-molecular-weight complex involved in biogenesis of early melanosomes, Hum Mol Genet, 9, 375, 10.1093/hmg/9.3.375 · DOI
  21. Chiang, 2003, The Hermansky–Pudlak syndrome 1 (HPS1) and HPS4 proteins are components of two complexes, BLOC-3 and BLOC-4, involved in the biogenesis of lysosome-related organelles, J Biol Chem, 278, 20332, 10.1074/jbc.M300090200 · DOI
  22. Martina, 2003, BLOC-3, a protein complex containing the Hermansky-Pudlak syndrome gene products HPS1 and HPS4, J Biol Chem, 278, 29376, 10.1074/jbc.M301294200 · DOI
  23. Nazarian, 2003, Biogenesis of lysosome-related organelles complex 3 (BLOC-3): a complex containing the Hermansky–Pudlak syndrome (HPS) proteins HPS1 and HPS4, Proc Natl Acad Sci USA, 100, 8770, 10.1073/pnas.1532040100 · DOI
  24. Jahn, 2003, Membrane fusion, Cell, 112, 519, 10.1016/S0092-8674(03)00112-0 · DOI
  25. Prekeris, 1998, Syntaxin 13 mediates cycling of plasma membrane proteins via tubulovesicular recycling endosomes, J Cell Biol, 143, 957, 10.1083/jcb.143.4.957 · DOI · Paper page
  26. Sun, 2003, Hrs regulates early endosome fusion by inhibiting formation of an endosomal SNARE complex, J Cell Biol, 162, 125, 10.1083/jcb.200302083 · DOI
  27. Taunton, 2000, Actin-dependent propulsion of endosomes and lysosomes by recruitment of N-WASP, J Cell Biol, 148, 519, 10.1083/jcb.148.3.519 · DOI
  28. Cordonnier, 2001, Actin filaments and myosin Iα cooperate with microtubules for the movement of lysosomes, Mol Biol Cell, 12, 4013, 10.1091/mbc.12.12.4013 · DOI
  29. van Deurs, 1995, Delivery to lysosomes in the human carcinoma cell line HEp-2 involves an actin filament-facilitated fusion between mature endosomes and preexisting lysosomes, Eur J Cell Biol, 66, 309
  30. Eitzen, 2002, Remodeling of organelle-bound actin is required for yeast vacuole fusion, J Cell Biol, 158, 669, 10.1083/jcb.200204089 · DOI
  31. Drengk, 2003, A coat of filamentous actin prevents clustering of late-endosomal vacuoles in vivo, Curr Biol, 13, 1814, 10.1016/j.cub.2003.09.037 · DOI
  32. Kjeken, 2004, Fusion between phagosomes, early and late endosomes: a role for actin in fusion between late, but not early endocytic organelles, Mol Biol Cell, 15, 345, 10.1091/mbc.e03-05-0334 · DOI
  33. Durbeej, 2002, Muscular dystrophies involving the dystrophin-glycoprotein complex: an overview of current mouse models, Curr Opin Genet Dev, 12, 349, 10.1016/S0959-437X(02)00309-X · DOI
  34. Blake, 2002, Function and genetics of dystrophin and dystrophin-related proteins in muscle, Physiol Rev, 82, 291, 10.1152/physrev.00028.2001 · DOI
  35. Loh, 2001, Role of β-dystrobrevin in nonmuscle dystrophin-associated-protein-complex-like complexes in kidney and liver, Mol Cell Biol, 21, 7442, 10.1128/MCB.21.21.7442-7448.2001 · DOI
  36. Grady, 1999, Role for α-dystrobrevin in the pathogenesis of dystrophin-dependent muscular dystrophies, Nat Cell Biol, 1, 215, 10.1038/12034 · DOI
  37. Benson, 2004, Myospryn is a novel binding partner for dysbindin in muscle, J Biol Chem, 279, 10450, 10.1074/jbc.M312664200 · DOI
  38. Wixler, 1999, Identification of novel interaction partners for the conserved membrane proximal region of α-integrin cytoplasmic domains, FEBS Lett, 445, 351, 10.1016/S0014-5793(99)00151-9 · DOI
  39. Theriault, 1970, Ultrastructure of developing melanosomes in C57 black and pallid mice, Dev Biol, 23, 261, 10.1016/0012-1606(70)90098-9 · DOI
  40. Nguyen, 2002, Melanosome morphologies in murine models of Hermansky–Pudlak syndrome reflect blocks in organelle development, J Invest Dermatol, 119, 1156, 10.1046/j.1523-1747.2002.19535.x · DOI
  41. Boissy, 1998, Altered protein localization in melanocytes from Hermansky–Pudlak syndrome: support for the role of the HPS gene product in intracellular trafficking, Lab Invest, 78, 1037
  42. Gardner, 1997, The mouse pale ear (ep) mutation is the homologue of human Hermansky–Pudlak syndrome, Proc Natl Acad Sci USA, 94, 9238, 10.1073/pnas.94.17.9238 · DOI
  43. Suzuki, 2002, Hermansky–Pudlak syndrome is caused by mutations in HPS4, the human homolog of the mouse light-ear gene, Nat Genet, 30, 321, 10.1038/ng835 · DOI
  44. Feng, 2002, The Hermansky–Pudlak syndrome 1 (HPS1) and HPS2 genes independently contribute to the production and function of platelet dense granules, melanosomes and lysosomes, Blood, 99, 1651, 10.1182/blood.V99.5.1651.h8001651_1651_1658 · DOI
  45. Swank, 1998, Mouse models of Hermansky-Pudlak syndrome: a review, Pigment Cell Res, 11, 60, 10.1111/j.1600-0749.1998.tb00713.x · DOI
  46. Harada, 1998, Golgi vesiculation and lysosome dispersion in cells lacking cytoplasmic dynein, J Cell Biol, 141, 51, 10.1083/jcb.141.1.51 · DOI
  47. Cantalupo, 2001, Rab-interacting lysosomal protein (RILP): the Rab7 effector required for transport to lysosomes, EMBO J, 20, 683, 10.1093/emboj/20.4.683 · DOI · Paper page
  48. Jordens, 2001, The Rab7 effector protein RILP controls lysosomal transport by inducing the recruitment of dynein–dynactin motors, Curr Biol, 11, 1680, 10.1016/S0960-9822(01)00531-0 · DOI · Paper page
  49. Clark, 2003, Adaptor protein 3-dependent microtubule-mediated movement of lytic granules to the immunological synapse, Nat Immunol, 4, 1111, 10.1038/ni1000 · DOI

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Metadata

Authors
Dell’Angelica, E. C.
Venue
Current Opinion in Cell Biology
Publisher
Elsevier BV
Published
2004-08
Volume
16
Issue
4
Pages
458-464
ISSN
0955-0674
DOI
10.1016/j.ceb.2004.05.001
Cited by
149
References
1
Language
en
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