The DOI matches its Crossref record; 59 of the 59 references it cites were found in a registry or an index.
Lysosome-related organelles: driving post-Golgi compartments into specialisation
Open accessAbstract
Some cells harbour specialised lysosome-related organelles (LROs) that share features of late endosomes/lysosomes but are functionally, morphologically and/or compositionally distinct. Ubiquitous trafficking machineries cooperate with cell type specific cargoes to produce these organelles. Several genetic diseases are caused by dysfunctional LRO formation and/or motility. Many genes affected by these diseases have been recently identified, revealing new cellular components of the trafficking machinery. Current research reveals how the products of these genes cooperate to generate LROs and how these otherwise diverse organelles are related by the mechanisms through which they form.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“In the model proposed by Raposo et al. (47,48), the coated endosome (also referred to as a stage 1 melanosome) serves as a critical sorting point between endocytic and pre-melanosomal pathways, from which macromolecules are specifically directed into melanosomal or lysosomal pathways.”
From SLC24A5 encodes a trans-Golgi network protein with potassium-dependent sodium-calcium exchange activity that regulates human epidermal melanogenesis (2008) · cites this paper as [48]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
NEW CYTOPLASMIC COMPONENTS IN ARTERIAL ENDOTHELIA
Weibel, E. R., & Palade, G. E. (1964) · The Journal of Cell Biology · doi:10.1083/jcb.23.1.101 · Cited by 1,080
Feldmann, J., Callebaut, I., Raposo, G., Dogniaux, S., Bacq, D., Dumont, C., Lambert, N., Ouachée-Chardin, M., Chédeville, G., Tamary, H., et al. (2003) · Cell · doi:10.1016/s0092-8674(03)00855-9 · Cited by 935
Self-citationFunctional Amyloid Formation within Mammalian Tissue
Fowler, D. M., Koulov, A. V., Alory, C., Marks, M. S., Balch, W. E., & Kelly, J. W. (2005) · PLoS Biology · doi:10.1371/journal.pbio.0040006 · Cited by 847
Self-citationCentrosome polarization delivers secretory granules to the immunological synapse
Stinchcombe, J. C., Majorovits, E., Bossi, G., Fuller, S., & Griffiths, G. M. (2006) · Nature · doi:10.1038/nature05071 · Cited by 599
The melanosome: membrane dynamics in black and white
Marks, M. S., & Seabra, M. C. (2001) · Nature Reviews Molecular Cell Biology · doi:10.1038/35096009 · Cited by 464
Self-citationRaposo, G., Tenza, D., Murphy, D. M., Berson, J. F., & Marks, M. S. (2001) · The Journal of Cell Biology · doi:10.1083/jcb.152.4.809 · Cited by 451
Self-citationLinking Albinism and Immunity: The Secrets of Secretory Lysosomes
Stinchcombe, J. C., Bossi, G., & Griffiths, G. M. (2004) · Science · doi:10.1126/science.1095291 · Cited by 361
Peden, A. A., Oorschot, V. M. J., Hesser, B. A., Austin, C. D., Scheller, R. H., & Klumperman, J. (2004) · The Journal of Cell Biology · doi:10.1083/jcb.200311064 · Cited by 357
Modulation of Receptor Recycling and Degradation by the Endosomal Kinesin KIF16B
Hoepfner, S., Severin, F. F., Cabezas, A., Habermann, B. H., Runge, A., Gillooly, D. J., Stenmark, H., & Zerial, M. (2005) · Cell · doi:10.1016/j.cell.2005.02.017 · Cited by 327
Pmel17 initiates premelanosome morphogenesis within multivesicular bodies
Berson, J. F., Harper, D. C., Tenza, D., Raposo, G., & Marks, M. S. (2001) · Molecular Biology of the Cell · doi:10.1091/mbc.12.11.3451 · Cited by 326
Self-citation
Flagged first, then by citations
Cited by
Sorted by citations
Items 201–214 of 214
El papel del calcio intravesicular en la secreción celular de líneas neuroendocrinas
Escudero, P. M. M. (2016) · UVaDOC UVaDOC University of Valladolid Documentary Repository (University of Valladolid) · doi:10.35376/10324/22213
Revisiting old questions to yield new insights
Berruti, G., & Paiardi, C. (2011) · Cited by 1
Frydman, G. H., Pate, K. A. M., & Vitsky, A. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-801238-3.64247-2
Artinger, K. (2021) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.735847584.793583903
Fukuda, M., & Ohbayashi, N. (2020) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.735464281.793574979
Lipofuscinose ceróide neuronal: manifestação fenotípica de uma série de casos CLN6
Ramos, M. I. S. D. N. (2022) · doi:10.11606/d.17.2022.tde-03022023-151211
Frydman, G. H., Pate, K. A. M., & Vitsky, A. (2024) · Elsevier eBooks · doi:10.1016/b978-0-323-95488-4.00135-2
Maturation stage-specific V-ATPase disassembly can explain neutral pH of lysosome-related organellesPreprint
Pradhan, A., Tadasare, N. N., Sarkar, D., Maurya, V., Bansal, L. K., Turkewitz, A. P., & Kumar, S. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.01.13.632790
Liu, D., Zhang, Y., Liu, X., Huang, Q., Zhang, X., Yang, R., Zhao, Y., Li, P., He, J., Zhang, K., et al. (2024) · Frigid Zone Medicine · doi:10.1515/fzm-2024-0021
Autolamellasomes: Linking Autophagy-Dependent ER Degradation to Whorled Lysosome BiogenesisPreprint
Lu, D., Zhang, R., Shi, W., Zhan, D., Yang, Y., Sun, X., Zhang, H., Li, Y., Li, X., & Yu, L. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.11.16.688694
Ho, H., Aruri, J., Ahmed, S., & Ganesan, A. K. (2010) · RNA technologies · doi:10.1007/978-3-642-12168-5_10
Investigating the role of SLC24A5 in Xenopus laevis pigmentation development
Williams, R. M. (2011) · UEA Digital Repository (University of East Anglia)
Schröder, H. C., Neufurth, M., Wang, X., & Müller, W. E. G. (2026) · Progress in molecular and subcellular biology · doi:10.1007/978-3-032-17771-1_8
Sleep-wake regulation by Palladin via the blood-brain-barrier
Li, H. (2022) · theses.fr (ABES) · doi:10.70675/6142554dzdf7dz4640z8c76ze90c5609291d
Metadata
- Authors
- Raposo, G., Marks, M. S., & Cutler, D. F.
- Affiliations
- Centre National de la Recherche Scientifique (FR)
- University of Pennsylvania (US)
- MRC Laboratory for Molecular Cell Biology (GB)
- Corresponding author
- Raposo, Graça
- Cutler, Daniel F
- Venue
- Current Opinion in Cell Biology
- Publisher
- Elsevier BV
- Published
- 2007-08
- Volume
- 19
- Issue
- 4
- Pages
- 394-401
- ISSN
- 0955-0674 (ISSN-L)
- PMC
- PMC2782641
- OpenAlex
- W2062800617
- Cited by
- 215
- References
- 59
- Citations by year
- 2026: 2 · 2025: 7 · 2024: 10 · 2023: 4 · 2022: 8 · 2021: 14 · 2020: 5 · 2019: 9 · 2018: 4 · 2017: 10 · 2016: 17 · 2015: 11 · 2014: 10 · 2013: 20 · 2012: 16
- FWCI
- 1.24
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Current Opinion in Cell Biology (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- UCL Discovery (University College London) (submittedVersion)
- Funders
- Centre National de la Recherche Scientifique
- National Institutes of Health (5r01ar048155-13)
- Medical Research Council
- National Eye Institute (R01EY015625)
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (R01 AR-048155)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Cellular transport and secretion
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Autophagy in Disease and Therapy
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Physiology › Calcium signaling and nucleotide metabolism
- Keywords
- lysosome-related organelles, late endosomes, lysosomes, post-Golgi trafficking, organelle biogenesis, organelle motility, lysosomal storage disease
- MeSH terms
- rab27 GTP-Binding Proteins, Animals, Cell Compartmentation, Golgi Apparatus, Humans, Lysosomes, Endosomes, Organelles, Melanosomes, rab GTP-Binding Proteins, Protein Sorting Signals
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
