The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Microtubule-severing enzymes
Open accessAbstract
In 1993, an enzyme with an ATP-dependent microtubule-severing activity was purified from sea urchin eggs and named katanin, after the Japanese word for sword. Now we know that katanin, spastin, and fidgetin form a family of closely related microtubule-severing enzymes that is widely distributed in eukaryotes ranging from Tetrahymena and Chlamydomonas to humans. Here we review the diverse in vivo functions of these proteins and the recent significant advances in deciphering the biophysical mechanism of microtubule severing.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
An Essential Role for Katanin in Severing Microtubules in the Neuron
Ahmad, F. J., Yu, W., McNally, F. J., & Baas, P. W. (1999) · The Journal of Cell Biology · doi:10.1083/jcb.145.2.305 · Cited by 253
Self-citation
Cited by
Zempel, H., Luedtke, J., Kumar, Y., Biernat, J., Dawson, H., Mandelkow, E., & Mandelkow, E. (2013) · The EMBO Journal · doi:10.1038/emboj.2013.207 · Cited by 283
Severing enzymes amplify microtubule arrays through lattice GTP-tubulin incorporation
Vemu, A., Szczesna, E., Zehr, E. A., Spector, J. O., Grigorieff, N., Deaconescu, A. M., & Roll-Mecak, A. (2018) · Science · doi:10.1126/science.aau1504 · Cited by 210
Self-citationAurora at the pole and equator: overlapping functions of Aurora kinases in the mitotic spindle
Hochegger, H., Hégarat, N., & Pereira-Leal, J. B. (2013) · Open Biology · doi:10.1098/rsob.120185 · Cited by 112
The postmitotic midbody: Regulating polarity, stemness, and proliferation
Peterman, E., & Prekeris, R. (2019) · Journal of Cell Biology · doi:10.1083/jcb.201906148 · Cited by 60
The evolutionary history of human spindle genes includes back-and-forth gene flow with Neandertals
Peyrégne, S., Kelso, J., Peter, B. M., & Pääbo, S. (2022) · eLife · doi:10.7554/elife.75464 · Cited by 24
Metadata
- Authors
- Roll-Mecak, A., & McNally, F. J.
- Venue
- Current Opinion in Cell Biology
- Publisher
- Elsevier BV
- Published
- 2010-02
- Volume
- 22
- Issue
- 1
- Pages
- 96-103
- ISSN
- 0955-0674 (ISSN-L)
- OpenAlex
- W2048586937
- Cited by
- 285
- References
- 1
- FWCI
- 0.84
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Microtubule-severing enzymes. https://app.cochat.ai/papers/10.1016/j.ceb.2009.11.001
- The paper
- Roll-Mecak, A., & McNally, F. J. (2010). Microtubule-severing enzymes. Current Opinion in Cell Biology. https://doi.org/10.1016/j.ceb.2009.11.001
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.