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Cited by 506

The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.

Secretory autophagy

Open access
Ponpuak, Marisa, Mandell, Michael A, Kimura, Tomonori, Chauhan, Santosh, Cleyrat, Cédric, Deretic, Vojo·2015·Current Opinion in Cell Biology

Abstract

Autophagy, once viewed exclusively as a cytoplasmic auto-digestive process, has its less intuitive but biologically distinct non-degradative roles. One manifestation of these functions of the autophagic machinery is the process termed secretory autophagy. Secretory autophagy facilitates unconventional secretion of the cytosolic cargo such as leaderless cytosolic proteins, which unlike proteins endowed with the leader (N-terminal signal) peptides cannot enter the conventional secretory pathway normally operating via the endoplasmic reticulum and the Golgi apparatus. Secretory autophagy may also export more complex cytoplasmic cargo and help excrete particulate substrates. Autophagic machinery and autophagy as a process also affect conventional secretory pathways, including the constitutive and regulated secretion, as well as promote alternative routes for trafficking of integral membrane proteins to the plasma membrane. Thus, autophagy and autophagic factors are intimately intertwined at many levels with secretion and polarized sorting in eukaryotic cells.

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Crossref · 10.1016/j.ceb.2015.04.016

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Metadata

Authors
Ponpuak, M., Mandell, M. A., Kimura, T., Chauhan, S., Cleyrat, C., & Deretic, V.
Venue
Current Opinion in Cell Biology
Publisher
Elsevier BV
Published
2015-08
Volume
35
Pages
106-116
ISSN
0955-0674 (ISSN-L)
OpenAlex
W4243182520
Cited by
506
References
19
FWCI
6.40
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Secretory autophagy. https://app.cochat.ai/papers/10.1016/j.ceb.2015.04.016
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Ponpuak, M., Mandell, M. A., Kimura, T., Chauhan, S., Cleyrat, C., & Deretic, V. (2015). Secretory autophagy. Current Opinion in Cell Biology. https://doi.org/10.1016/j.ceb.2015.04.016

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.