Cancer cell metabolism: warburg and beyond

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Items 401–500 of 1,006

1. Phosphoglycerate mutase 1 promotes cancer cell migration independent of its metabolic activity
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2. Cancer Metabolism: Fueling More than Just Growth
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3. T cells and their immunometabolism: A novel way to understanding sepsis immunopathogenesis and future therapeutics
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4. Metabolomics of human breast cancer: new approaches for tumor typing and biomarker discovery
   Carsten Denkert, Elmar Bucher, Mika Hilvo, Reza M. Salek, Matej Orešič, Julian Leether Griffin, Scarlet F. Brockmöller, Frederick Klauschen, Sibylle Loibl, Dinesh Kumar Barupal et al. · 2012 · Genome Medicine
5. MicroRNA-224 inhibits progression of human prostate cancer by downregulating TRIB1
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6. Proton transport inhibitors as potentially selective anticancer drugs.
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7. Predicting Drug Targets and Biomarkers of Cancer via Genome-Scale Metabolic Modeling
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8. L-lactic acidosis: pathophysiology, classification, and causes; emphasis on biochemical and metabolic basis
   Kamel S. Kamel, Man Seok Oh, Mitchell Lewis Halperin · 2019 · Kidney International
9. Could ketogenic diet “starve” cancer? Emerging evidence
   Luigi Barrea, Massimiliano Caprio, Dario Tuccinardi, Eleonora Moriconi, Laura Di Renzo, Giovanna Muscogiuri, Annamaria Colao, Silvia Savastano, on behalf of the Obesity Programs of nutrition, Education, Research and Assessment (OPERA) group · 2020 · Critical Reviews in Food Science and Nutrition
10. Platinum–Titania Schottky Junction as Nanosonosensitizer, Glucose Scavenger, and Tumor Microenvironment-Modulator for Promoted Cancer Treatment
    Yinmin Zhao, Jiahui Liu, Mengting He, Qi Dong, Lei Zhang, Zhigang Xu, Yuejun Kang, Peng Xue · 2022 · ACS Nano
11. Radiation induces senescence and a bystander effect through metabolic alterations
    E-C Liao, Y-T Hsu, Q-Y Chuah, Y. J. Lee, J-Y Hu, T-C Huang, Pei‐Ming Yang, S-J Chiu · 2014 · Cell Death and Disease
12. Chaetocin-induced ROS-mediated apoptosis involves ATM–YAP1 axis and JNK-dependent inhibition of glucose metabolism
    D. Dixit, R. Ghildiyal, N. P. Anto, Ellora Sen · 2014 · Cell Death and Disease
13. High Expression of CPT1A Predicts Adverse Outcomes: A Potential Therapeutic Target for Acute Myeloid Leukemia
    Jinlong Shi, Huaping Fu, Zhilong Jia, Kunlun He, Lin Na Fu, Weidong Wang · 2016 · EBioMedicine
14. Peroxiredoxin Involvement in the Initiation and Progression of Human Cancer
    Mark B. Hampton, Kate Angela Vick, John Skoko, Carola Anke Neumann · 2017 · Antioxidants and Redox Signaling
15. Metabolic flexibility in melanoma: A potential therapeutic target
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16. Nano-enabled theranostics for cancer
    Palani Sharmiladevi, Koyeli Girigoswami, Viswanathan Haribabu, Agnishwar Girigoswami · 2021 · Materials Advances
17. Metabolomics of B to plasma cell differentiation
    Garcia-Manteiga, Jose Manuel, Mari, Silvia, Godejohann, Markus, Spraul, Manfred, Napoli, Claudia, Cenci, Simone, Musco, Giovanna, Sitia, Roberto · 2011 · Journal of Proteome Research
18. Glyceraldehyde‐3‐phosphate dehydrogenase promotes liver tumorigenesis by modulating phosphoglycerate dehydrogenase
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19. pH-Responsive nanoparticles based on cholesterol/imidazole modified oxidized-starch for targeted anticancer drug delivery
    Yongbin Xu, Yaxin Zi, Jinfeng Lei, Xingyue Mo, Zilun Shao, Yuyao Wu, Ye Tian, Defu Li, Changdao Mu · 2020 · Carbohydrate Polymers
20. Consensus-Phenotype Integration of Transcriptomic and Metabolomic Data Implies a Role for Metabolism in the Chemosensitivity of Tumour Cells
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21. Magnetic nanoparticles for ferroptosis cancer therapy with diagnostic imaging
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22. The lactate sensor GPR81 regulates glycolysis and tumor growth of breast cancer
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23. Molecular mechanisms of mTOR regulation by stress
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24. A novel self-lipid antigen targets human T cells against CD1c+ leukemias
    Marco Lepore, Claudia de Lalla, Seetaramanjaneyulu Gundimeda, Heiko Gsellinger, Michela Consonni, Claudio Garavaglia, Sebastiano Sansano, Francesco M. Piccolo, Andrea Scelfo, Daniel Häußinger et al. · 2014 · The Journal of Experimental Medicine
25. Tumor suppressor NDRG2 inhibits glycolysis and glutaminolysis in colorectal cancer cells by repressing c-Myc expression
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26. Imaging metabolic heterogeneity in cancer
    Debanti Sengupta, Guillem Pratx · 2016 · Molecular Cancer
27. Metabolic reprogramming identifies the most aggressive lesions at early phases of hepatic carcinogenesis
    Marta Anna Kowalik, Giulia Guzzo, Andrea Morandi, Andrea Perra, Silvia Menegon, Ionica Masgras, Elena Trevisan, Maria Maddalena Angioni, Francesca Fornari, Luca Quagliata et al. · 2016 · Oncotarget
28. Phenotypic Plasticity and Cell Fate Decisions in Cancer: Insights from Dynamical Systems Theory
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29. Beyond the Warburg Effect: Oxidative and Glycolytic Phenotypes Coexist within the Metabolic Heterogeneity of Glioblastoma
    Tomás Duraj, Noemí Garcia‐Romero, Josefa Carrión-Navarro, Rodrigo Madurga, Ana Ortiz de Méndivil, Ricardo Prat-Acín, Lina García‐Cañamaque, Ángel Ayuso‐Sacido · 2021 · Cells
30. The Role of Bioactive Compounds in Natural Products Extracted from Plants in Cancer Treatment and Their Mechanisms Related to Anticancer Effects
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31. Ferroptosis in life: To be or not to be
    Ling Xu, Yue Liu, Xi Chen, H. Zhong, Yi Wang · 2023 · Biomedicine & Pharmacotherapy
32. Induction of Glucose Metabolism in Stimulated T Lymphocytes Is Regulated by Mitogen-Activated Protein Kinase Signaling
    Aimee J. Marko, Rebecca Miller, Alina Kelman, Kenneth A. Frauwirth · 2010 · PLoS ONE
33. The Intercellular Metabolic Interplay between Tumor and Immune Cells
    Tingting Wang, Guangwei Liu, Ruoning Wang · 2014 · Frontiers in Immunology
34. Metabolic Reprogramming and Dependencies Associated with Epithelial Cancer Stem Cells Independent of the Epithelial-Mesenchymal Transition Program
    Esther Aguilar, Igor Marín de Mas, Erika Zodda, Silvia Marín, Fionnuala M. Morrish, Vitaly A. Selivanov, Óscar Meca‐Cortés, Hossain Delowar, Mònica Pons, Inés Izquierdo et al. · 2016 · Stem Cells
35. TOR and ageing: a complex pathway for a complex process
    Mark A. McCormick, Shih‐Yin Tsai, Brian Keith Kennedy · 2010 · Philosophical Transactions of the Royal Society B Biological Sciences
36. Glutamine Metabolism Regulates the Pluripotency Transcription Factor OCT4
    Glenn Marsboom, Guofang Zhang, Nicole M. Pohl-Avila, Yanmin Zhang, Yuan Yang, Hojin Kang, Bo Hao, Henri Brunengraber, Asrar B. Malik, Jalees Rehman · 2016 · Cell Reports
37. Apigenin Restrains Colon Cancer Cell Proliferation via Targeted Blocking of Pyruvate Kinase M2-Dependent Glycolysis
    Shuhua Shan, Jiangying Shi, Peng Yang, Bin Jia, Haili Wu, Xiaoli Zhang, Zhuoyu Li · 2017 · Journal of Agricultural and Food Chemistry
38. Identifying Tightly Regulated and Variably Expressed Networks by Differential Rank Conservation (DIRAC)
    James A. Eddy, Leroy Hood, Nathan D. Price, Donald Geman · 2010 · PLoS Computational Biology
39. Network Analysis of a Pkd1-Mouse Model of Autosomal Dominant Polycystic Kidney Disease Identifies HNF4α as a Disease Modifier
    Luís F. Menezes, Fang Zhou, Andrew D. Patterson, Klaus B. Piontek, Kristopher W. Krausz, Frank J. Gonzalez, Gregory George Germino · 2012 · PLoS Genetics
40. Combinatorial CRISPR-Cas9 Metabolic Screens Reveal Critical Redox Control Points Dependent on the KEAP1-NRF2 Regulatory Axis
    Dongxin Zhao, Mehmet G. Badur, Jens Luebeck, Jose H. Magaña, Amanda Birmingham, Roman Šášik, Christopher S. Ahn, Trey Ideker, Christian M. Metallo, Prashant Mali · 2018 · Molecular Cell
41. SLC2A5 promotes lung adenocarcinoma cell growth and metastasis by enhancing fructose utilization
    Yuanyuan Weng, Xueyu Fan, Yongfeng Bai, Siwei Wang, Hui Huang, Huimin Yang, Jin Zhu, Feng Zhang · 2018 · Cell Death Discovery
42. Serine and one-carbon metabolism, a bridge that links mTOR signaling and DNA methylation in cancer.
    Ju-Deng Zeng, W. Wu, Hui-Yun Wang, Xiao-Xing Li · 2019 · Pharmacological Research
43. Metabolomics, metabolic flux analysis and cancer pharmacology
    Lingfan Liang, Fei Sun, Hongbo Wang, Zeping Hu · 2021 · Pharmacology & Therapeutics
44. Cellular O-Glycome Reporter/Amplification to explore O-glycans of living cells
    Matthew R. Kudelka, Aristotelis Antonopoulos, Yingchun Wang, Duc Minh Duong, Xuezheng Song, Nicholas T. Seyfried, Anne Dell, Stuart M. Haslam, Richard D. Cummings, Tongzhong Ju · 2015 · Nature Methods
45. The reciprocal function and regulation of tumor vessels and immune cells offers new therapeutic opportunities in cancer
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46. MicroRNA-124 Reduces the Pentose Phosphate Pathway and Proliferation by Targeting PRPS1 and RPIA mRNAs in Human Colorectal Cancer Cells
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47. Herpesviruses shape tumour microenvironment through exosomal transfer of viral microRNAs
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48. Long noncoding RNA DIO3OS induces glycolytic-dominant metabolic reprogramming to promote aromatase inhibitor resistance in breast cancer
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49. The novel hypoxia-inducible factor-1α inhibitor IDF-11774 regulates cancer metabolism, thereby suppressing tumor growth
    Hyun Seung Ban, Bo‐Kyung Kim, Hongsub Lee, Hwan Mook Kim, Dipesh S. Harmalkar, Miso Nam, Song‐Kyu Park, Kiho Lee, Joon-Tae Park, Inhyub Kim et al. · 2017 · Cell Death and Disease
50. LDH-A promotes malignant behavior via activation of epithelial-to-mesenchymal transition in lung adenocarcinoma
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51. Enzyme‐Engineered Conjugated Polymer Nanoplatform for Activatable Companion Diagnostics and Multistage Augmented Synergistic Therapy
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52. Identification of substituted 2-thio-6-oxo-1,6-dihydropyrimidines as inhibitors of human lactate dehydrogenase
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53. Choline kinase inhibition in rheumatoid arthritis
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54. Delineating metabolic signatures of head and neck squamous cell carcinoma: Phospholipase A, a potential therapeutic target
    Pratima Tripathi, Pachiyappan Kamarajan, Bagganahalli S. Somashekar, Neil MacKinnon, Arul M. Chinnaiyan, Yvonne Lorraine Kapila, Thekkelnaycke M. Rajendiran, Ayyalusamy Ramamoorthy · 2012 · The International Journal of Biochemistry & Cell Biology
55. Metabolic defects provide a spark for the epigenetic switch in cancer
    Michael James Hitchler, Frederick E. Domann · 2009 · Free Radical Biology and Medicine
56. Isotopically nonstationary 13C flux analysis of Myc-induced metabolic reprogramming in B-cells
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57. The biological activities of protein/oleic acid complexes reside in the fatty acid
    Angelo Fontana, Barbara Spolaore, Patrizia Polverino de Laureto · 2013 · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
58. Mitochondrial recoupling: a novel therapeutic strategy for cancer
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59. Glucose starvation induces cell death in K-ras-transformed cells by interfering with the hexosamine biosynthesis pathway and activating the unfolded protein response
    Roberta Palorini, Francesco Paolo Cammarata, Chiara Balestrieri, Andrea Monestiroli, Michele Vasso, Cecilia Gelfi, Lilia Alberghina, Ferdinando Chiaradonna · 2013 · Cell Death and Disease
60. High throughput estimation of functional cell activities reveals disease mechanisms and predicts relevant clinical outcomes
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61. New method for algae comprehensive utilization: Algae-derived biochar enhances algae anaerobic fermentation for short-chain fatty acids production
    Xu Duan, Yunzhi Chen, Yuanyuan Yan, Leiyu Feng, Yinguang Chen, Qi Zhou · 2019 · Bioresource Technology
62. Regulators of glucose uptake in thyroid cancer cell lines
    Shabnam Heydarzadeh, Ali Asghar Moshtaghie, Maryam Sadat Daneshpoor, Mehdi Hedayati · 2020 · Cell Communication and Signaling
63. Monitoring Mitochondrial Pyruvate Carrier Activity in Real Time Using a BRET-Based Biosensor: Investigation of the Warburg Effect
    Vincent Compan, Sandra Pierredon, Benoît Vanderperre, Petra Krznar, Ibtissam Marchiq, Nicola Zamboni, Jacques Pouysségur, Jean‐Claude Martinou · 2015 · Molecular Cell
64. Extracellular Lumican Inhibits Pancreatic Cancer Cell Growth and Is Associated with Prolonged Survival after Surgery
    Xinqun Li, Mark A. Truty, Ya’an Kang, Xavier Chopin‐Laly, Ran Zhang, David Roife, Deyali Chatterjee, E. H. Lin, Ryan Michael Thomas, Huamin Wang et al. · 2014 · Clinical Cancer Research
65. Small compound inhibitors of basal glucose transport inhibit cell proliferation and induce apoptosis in cancer cells via glucose-deprivation-like mechanisms
    Yi Liu, Weihe Zhang, Yanyan Cao, Yan Liu, Stephen C. Bergmeier, Xiaozhuo Chen · 2010 · Cancer Letters
66. Solute carriers (SLCs) in cancer
    Sara El-Gebali, Susanne Bentz, Matthias A. Hediger, Pascale Anderle · 2013 · Molecular Aspects of Medicine
67. Phosphoglycerate dehydrogenase is dispensable for breast tumor maintenance and growth
    Chen, Jinyun, Chung, Franklin, Yang, Guizhi, Pu, Minying, Gao, Hui, Jiang, Wei, Yin, Hong, Capka, Vladimir, Kasibhatla, Shailaja, Laffitte, Bryan et al. · 2013 · Oncotarget
68. Oncoprotein HBXIP Modulates Abnormal Lipid Metabolism and Growth of Breast Cancer Cells by Activating the LXRs/SREBP-1c/FAS Signaling Cascade
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69. Non-coding RNAs in the reprogramming of glucose metabolism in cancer
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70. Anti-Warburg effect of rosmarinic acid via miR-155 in gastric cancer cells
    Li Zhou, Shuai Han, Shaohua Yang, Zhai Cai, Dongyue Pan, Zong-hai Huang, Pusheng Zhang, Huijuan Zhu, Lijun Lei, Weiwei Wang · 2015 · Drug Design Development and Therapy
71. Redox-Based Escape Mechanism from Death: The Cancer Lesson
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72. Cross-talk between HIF and p53 as mediators of molecular responses to physiological and genotoxic stresses
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73. The incredible ULKs
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74. Dichloroacetate shifts the metabolism from glycolysis to glucose oxidation and exhibits synergistic growth inhibition with cisplatin in HeLa cells
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75. One-pot synthesis of pH-responsive charge-switchable PEGylated nanoscale coordination polymers for improved cancer therapy
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76. Silencing PFKP inhibits starvation-induced autophagy, glycolysis, and epithelial mesenchymal transition in oral squamous cell carcinoma
    Guanhui Chen, Haichao Liu, Yadong Zhang, Jianfeng Liang, Yue Zhu, Ming Zhang, Dongsheng Yu, Cheng Wang, Jinsong Hou · 2018 · Experimental Cell Research
77. Exploring the Influence of Cell Metabolism on Cell Fate through Protein Post-translational Modifications
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78. A mitochondrial unfolded protein response inhibitor suppresses prostate cancer growth in mice via HSP60
    Rahul Kumar, Ajay Kumar Chaudhary, Jordan Woytash, Joseph R. Inigo, Abhiram Gokhale, Wiam Bshara, Kristopher M. Attwood, Jianmin Wang, Joseph A. Spernyak, Eva Rath et al. · 2022 · Journal of Clinical Investigation
79. The regulatory roles and clinical significance of glycolysis in tumor
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80. Paradoxical role of autophagy in the dysplastic and tumor-forming stages of hepatocarcinoma development in rats
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81. Metabolic consequences of LDHA inhibition by epigallocatechin gallate and oxamate in MIA PaCa-2 pancreatic cancer cells
    Qing‐Yi Lu, Lifeng Zhang, Jennifer K. Yee, Vay‐Liang W. Go, Wai‐Nang Paul Lee · 2014 · Metabolomics
82. Pyruvate Kinase M2 Expression, but Not Pyruvate Kinase Activity, Is Up-Regulated in a Grade-Specific Manner in Human Glioma
    Joydeep Mukherjee, Joanna J. Phillips, Shichun Zheng, John K. Wiencke, Sabrina M. Ronen, Russell O. Pieper · 2013 · PLoS ONE
83. Metabolic Alterations in Lung Cancer–Associated Fibroblasts Correlated with Increased Glycolytic Metabolism of the Tumor
    Virendra K. Chaudhri, Gregory G. Salzler, Salihah A. Dick, Melanie S. Buckman, Raffaella Sordella, Edward D. Karoly, Robert P. Mohney, Brendon Matthew Stiles, Olivier Elemento, Nasser Khaled Altorki et al. · 2013 · Molecular Cancer Research
84. Photodynamic Therapy Based on Nanoscale Metal–Organic Frameworks: From Material Design to Cancer Nanotherapeutics
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85. De novo synthesis and salvage pathway coordinately regulate polyamine homeostasis and determine T cell proliferation and function
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86. Breast Cancer Stem Cells Secrete MIF to Mediate Tumor Metabolic Reprogramming That Drives Immune Evasion
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87. Prognostic Significance of Serum Lactic Acid, Lactate Dehydrogenase, and Albumin Levels in Patients with Metastatic Colorectal Cancer
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88. Role of the gut microbiome for cancer patients receiving immunotherapy: Dietary and treatment implications
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89. LncRNAs in tumor metabolic reprogramming and immune microenvironment remodeling
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90. The role of p53 in glucose metabolism
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91. Glutamine deprivation stimulates mTOR-JNK-dependent chemokine secretion
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92. Respiratory chain complex II as general sensor for apoptosis
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93. Mouse Genetics Suggests Cell-Context Dependency for Myc-Regulated Metabolic Enzymes during Tumorigenesis
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94. Metformin increases PDH and suppresses HIF-1α under hypoxic conditions and induces cell death in oral squamous cell carcinoma
    Talita Antunes Guimarães, Lucyana Conceição Farias, Eliane Sobrinho Santos, Carlos Alberto de Carvalho Fraga, Lissur Azevedo Orsine, Leandro de Freitas Teles, John David Feltenberger, Sabrina Ferreira de Jesus, Marcela Gonçalves de Souza, Sérgio Henrique Sousa Santos et al. · 2016 · Oncotarget
95. Effects of canagliflozin on growth and metabolic reprograming in hepatocellular carcinoma cells: Multi-omics analysis of metabolomics and absolute quantification proteomics (iMPAQT)
    Dan Nakano, Takumi Kawaguchi, Hideki Iwamoto, Masako Hayakawa, Hironori Koga, Takuji Torimura · 2020 · PLoS ONE
96. OSMR controls glioma stem cell respiration and confers resistance of glioblastoma to ionizing radiation
    Ahmad Sharanek, Audrey Burban, Matthew Laaper, Émilie Heckel, Jean‐Sébastien Joyal, Vahab D. Soleimani, Arezu Jahani‐Asl · 2020 · Nature Communications
97. Fragment Growing and Linking Lead to Novel Nanomolar Lactate Dehydrogenase Inhibitors
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98. Dlx-2 and glutaminase upregulate epithelial-mesenchymal transition and glycolytic switch
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99. A metabolomic approach to identifying platinum resistance in ovarian cancer
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100. Magnetic Resonance Imaging of Glucose Uptake and Metabolism in Patients with Head and Neck Cancer
     Jihong Wang, Joseph Weygand, Ken‐Pin Hwang, Abdallah Mohamed, Yao Ding, Clifton David Fuller, Stephen Yenzen Lai, Steven Jay Frank, Jinyuan Zhou · 2016 · Scientific Reports