Cancer cell metabolism: warburg and beyond

AKT/PKB signaling: navigating downstream

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The Rag GTPases Bind Raptor and Mediate Amino Acid Signaling to mTORC1

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Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis

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Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-α prolyl hydroxylase

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TIGAR, a p53-Inducible Regulator of Glycolysis and Apoptosis

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p53 Regulates Mitochondrial Respiration

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Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance

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A Mitochondria-K+ Channel Axis Is Suppressed in Cancer and Its Normalization Promotes Apoptosis and Inhibits Cancer Growth

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Regulation of TORC1 by Rag GTPases in nutrient response

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Oncogenic alterations of metabolism

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c-Myc transactivation of <i>LDH-A</i> : Implications for tumor metabolism and growth

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ATP citrate lyase inhibition can suppress tumor cell growth

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Increased Expression of Genes Converting Adrenal Androgens to Testosterone in Androgen-Independent Prostate Cancer

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Pyruvate kinase M2 is a phosphotyrosine-binding protein

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HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: Novel role of fumarate in regulation of HIF stability

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Accumulation of Krebs cycle intermediates and over-expression of HIF1α in tumours which result from germline FH and SDH mutations

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Hypoxia-inducible Factor 1 Activation by Aerobic Glycolysis Implicates the Warburg Effect in Carcinogenesis

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Pyruvate kinase type M2 and its role in tumor growth and spreading

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HIF and c-Myc: Sibling Rivals for Control of Cancer Cell Metabolism and Proliferation

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p53 regulates glucose metabolism through an IKK-NF-κB pathway and inhibits cell transformation

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GAPDH and Autophagy Preserve Survival after Apoptotic Cytochrome c Release in the Absence of Caspase Activation

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Comparison of Metabolic Pathways between Cancer Cells and Stromal Cells in Colorectal Carcinomas: a Metabolic Survival Role for Tumor-Associated Stroma

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Hypoxia and acidosis independently up-regulate vascular endothelial growth factor transcription in brain tumors in vivo.

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Perturbational profiling of a cell-line model of tumorigenesis by using metabolic measurements

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Lactate – a signal coordinating cell and systemic function

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Constitutive activation of hypoxia-inducible genes related to overexpression of hypoxia-inducible factor-1alpha in clear cell renal carcinomas.

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Targeting Vacuolar H+-ATPases as a New Strategy against Cancer

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Regulation of vascular endothelial growth factor expression by acidosis in human cancer cells

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Transformation of human mesenchymal stem cells increases their dependency on oxidative phosphorylation for energy production

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Colocalization of MCT1, CD147, and LDH in mitochondrial inner membrane of L6 muscle cells: evidence of a mitochondrial lactate oxidation complex

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House cleaning, a part of good housekeeping

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The H+-Linked Monocarboxylate Transporter (MCT1/SLC16A1): A Potential Therapeutic Target for High-Risk Neuroblastoma

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Negligible direct lactate oxidation in subsarcolemmal and intermyofibrillar mitochondria obtained from red and white rat skeletal muscle

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Small Interfering RNA-Mediated Suppression of dUTPase Sensitizes Cancer Cell Lines to Thymidylate Synthase Inhibition

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Hallmarks of Cancer: The Next Generation

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Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

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mTOR: from growth signal integration to cancer, diabetes and ageing

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Otto Warburg's contributions to current concepts of cancer metabolism

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Reactive oxygen species in cancer

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Photothermal therapy and photoacoustic imaging via nanotheranostics in fighting cancer

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Cellular Fatty Acid Metabolism and Cancer

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Chemodynamic Therapy: Tumour Microenvironment‐Mediated Fenton and Fenton‐like Reactions

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Functional genomics reveal that the serine synthesis pathway is essential in breast cancer

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Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression

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Tumor-selective catalytic nanomedicine by nanocatalyst delivery

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The Control of the Metabolic Switch in Cancers by Oncogenes and Tumor Suppressor Genes

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Smart cancer nanomedicine

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Nanomaterials for Theranostics: Recent Advances and Future Challenges

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Metabolic requirements for the maintenance of self-renewing stem cells

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Targeting Metabolism for Cancer Therapy

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Links between metabolism and cancerPreprint

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Targeting cellular metabolism to improve cancer therapeutics

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Energy metabolism of cancer: Glycolysis versus oxidative phosphorylation (Review)

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p53 and metabolism

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Cancer Cell Metabolism: One Hallmark, Many Faces

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ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect

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Glucose Deprivation Contributes to the Development of <i>KRAS</i> Pathway Mutations in Tumor Cells

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Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function

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PKM2 Phosphorylates Histone H3 and Promotes Gene Transcription and Tumorigenesis

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Metabolic Regulation of Hematopoietic Stem Cells in the Hypoxic Niche

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Constraint-based models predict metabolic and associated cellular functions

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JAK/STAT3-Regulated Fatty Acid β-Oxidation Is Critical for Breast Cancer Stem Cell Self-Renewal and Chemoresistance

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The world of protein acetylation

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SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress

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An Integrated Metabolic Atlas of Clear Cell Renal Cell Carcinoma

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The Warburg effect in tumor progression: Mitochondrial oxidative metabolism as an anti-metastasis mechanism

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Regional aerobic glycolysis in the human brain

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Lactate Regulates Metabolic and Pro-inflammatory Circuits in Control of T Cell Migration and Effector Functions

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Activation of SAT1 engages polyamine metabolism with p53-mediated ferroptotic responses

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Biomedicine Meets Fenton Chemistry

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Shifts in growth strategies reflect tradeoffs in cellular economics

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Extracellular vesicle-packaged HIF-1α-stabilizing lncRNA from tumour-associated macrophages regulates aerobic glycolysis of breast cancer cells

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Amino acids rather than glucose account for the majority of cell mass in proliferating mammalian cells

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Phosphofructokinase 1 Glycosylation Regulates Cell Growth and Metabolism

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Glycine decarboxylase activity drives non-small cell lung cancer tumor-initiating cells and tumorigenesis

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Metabolites and the Tumour Microenvironment: From Cellular Mechanisms to Systemic Metabolism

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Metabolomics in cancer research and emerging applications in clinical oncology

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