Metabolomics of B to plasma cell differentiation

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

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On the origin of cancer cells

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Cancer cell metabolism: warburg and beyond

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Metabonomics: a platform for studying drug toxicity and gene function

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Metabonomics

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HMDB: a knowledgebase for the human metabolome

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[1] Preparation of monoclonal antibodies: Strategies and procedures

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Uric Acid and Oxidative Stress

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Targeted Profiling: Quantitative Analysis of 1 H NMR Metabolomics Data

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Regulation of plasma-cell development

Shelef, M. A., & Calame, K. L. (2005) · Nature reviews. Immunology · doi:10.1038/nri1572 · Cited by 881 · see citing works

Fuel feeds function: energy metabolism and the T-cell response

Fox, C. J., Hammerman, P. S., & Thompson, C. B. (2005) · Nature reviews. Immunology · doi:10.1038/nri1710 · Cited by 841 · see citing works

Mammalian polyamine metabolism and function

Pegg, A. E. (2009) · IUBMB Life · doi:10.1002/iub.230 · Cited by 786 · see citing works

Measuring Protein Concentrations by NMR Spectroscopy

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Metabolic footprinting and systems biology: the medium is the message

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Immunoglobulin gene expression in transformed lymphoid cells.

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Antigen-presenting dendritic cells provide the reducing extracellular microenvironment required for T lymphocyte activation

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Sequential Waves of Functionally Related Proteins Are Expressed When B Cells Prepare for Antibody Secretion

van Anken, E., Romijn, E. P., Maggioni, C., Mezghrani, A., Sitia, R., Braakman, I., & Heck, A. J. R. (2003) · Immunity · doi:10.1016/s1074-7613(03)00024-4 · Cited by 352 · see citing works

A 1H‐NMR thermometer suitable for cryoprobes

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Ethanol: Novel End Product of Vertebrate Anaerobic Metabolism

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Developmental regulation of IgM secretion: The role of the carboxy-terminal cysteine

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Methylthioadenosine

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MetaboMiner – semi-automated identification of metabolites from 2D NMR spectra of complex biofluids

Xia, J., Bjorndahl, T. C., Tang, P., & Wishart, D. S. (2008) · BMC Bioinformatics · doi:10.1186/1471-2105-9-507 · Cited by 205 · see citing works

Mesenteric lymph nodes are critical for the induction of high-dose oral tolerance in the absence of Peyer's patches

Spahn, T. W., Weiner, H. L., Rennert, P. D., Lügering, N., Fontana, A., Domschke, W., & Kucharzik, T. F. (2002) · European Journal of Immunology · doi:10.1002/1521-4141(200204)32:4 · Cited by 194 · see citing works

A plasma signature of human mitochondrial disease revealed through metabolic profiling of spent media from cultured muscle cells

Shaham, O., Slate, N. G., Goldberger, O., Xu, Q., Ramanathan, A., Souza, A. L., Clish, C. B., Sims, K. B., & Mootha, V. K. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0906039107 · Cited by 146 · see citing works

Serum metabolome analysis by 1H-NMR reveals differences between chronic lymphocytic leukaemia molecular subgroups

MacIntyre, D. A., Jiménez, B., Lewintre, E. J., et al. (2010) · Leukemia · doi:10.1038/leu.2009.295 · Cited by 146 · see citing works

Metabolic footprinting in microbiology: methods and applications in functional genomics and biotechnology

Mapelli, V., Lisbeth Olsson, A., & Nielsen, J. (2008) · Trends in biotechnology · doi:10.1016/j.tibtech.2008.05.008 · Cited by 138 · see citing works

B- to Plasma-Cell Terminal Differentiation Entails Oxidative Stress and Profound Reshaping of the Antioxidant Responses

Bertolotti, M., Yim, S. H., García-Manteiga, J. M., Masciarelli, S., Kim, Y., Kang, M.-H., Iuchi, Y., Fujii, J., Venè, R., Rubartelli, A., et al. (2010) · Antioxidants and Redox Signaling · doi:10.1089/ars.2009.3079 · Cited by 125 · see citing works

The essential role of L‐glutamine in lymphocyte differentiation in vitro

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Formation of reversible disulfide bonds with the protein matrix of the endoplasmic reticulum correlates with the retention of unassembled Ig light chains.

Reddy, P. S., Sparvoli, A., Fagioli, C., Fassina, G., & Sitia, R. (1996) · The EMBO Journal · doi:10.1002/j.1460-2075.1996.tb00561.x · Cited by 125 · see citing works

Regulation of membrane IgM expression in secretory B cells: translational and post‐translational events.

Sitia, R., Neuberger, M. S., & Milstein, C. (1987) · The EMBO Journal · doi:10.1002/j.1460-2075.1987.tb02739.x · Cited by 123 · see citing works

Ethanol Metabolism and Effects: Nitric Oxide and its Interaction

Deng, X., & Deitrich, R. A. (2007) · Current Clinical Pharmacology · doi:10.2174/157488407780598135 · Cited by 121 · see citing works

Metabolic footprinting as a tool for discriminating between brewing yeasts

Pope, G. A., MacKenzie, D. A., Defernez, M., Aroso, M., Fuller, L. J., Mellon, F. A., Dunn, W. B., Brown, M., Goodacre, R., Kell, D. B., et al. (2007) · Yeast · doi:10.1002/yea.1499 · Cited by 112 · see citing works

Extracellular metabolomics: A metabolic footprinting approach to assess fiber degradation in complex media

Villas-Bôas, S. G., Noel, S. J., Lane, G. A., Attwood, G. T., & Cookson, A. L. (2005) · Analytical Biochemistry · doi:10.1016/j.ab.2005.11.019 · Cited by 108 · see citing works

Redox Remodeling Allows and Controls B-Cell Activation and Differentiation

Venè, R., Delfino, L., Castellani, P., Balza, E., Bertolotti, M., Sitia, R., & Rubartelli, A. (2010) · Antioxidants and Redox Signaling · doi:10.1089/ars.2009.3078 · Cited by 102 · see citing works

Changes in the Metabolic Footprint of Placental Explant-Conditioned Culture Medium Identifies Metabolic Disturbances Related to Hypoxia and Pre-Eclampsia

Dunn, W. B., Brown, M., Worton, S. A., Crocker, I. P., Broadhurst, D., Horgan, R., Kenny, L. C., Baker, P. N., Kell, D. B., & Heazell, A. E. P. (2009) · Placenta · doi:10.1016/j.placenta.2009.08.008 · Cited by 87 · see citing works

Metabolic acclimation to hypoxia revealed by metabolite gradients in melon fruit

Biais, B., Beauvoit, B. P., Allwood, J. W., et al. (2009) · Journal of Plant Physiology · doi:10.1016/j.jplph.2009.08.010 · Cited by 80 · see citing works

Expression Clustering Reveals Detailed Co-expression Patterns of Functionally Related Proteins during B Cell Differentiation

Romijn, E. P., Christis, C., Wieffer, M., Gouw, J. W., Fullaondo, A., van der Sluijs, P., Braakman, I., & Heck, A. J. R. (2005) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m500123-mcp200 · Cited by 71 · see citing works

Direct demonstration of no formation in vivo from organic nitrites and nitrates, and correlation to effects on blood pressure and to in vitro effects

Cederqvist, B., Persson, M. G., & Gustafsson, L. E. (1994) · Biochemical Pharmacology · doi:10.1016/0006-2952(94)90416-2 · Cited by 65 · see citing works

Mice Heterozygous for Germ-line Mutations in Methylthioadenosine Phosphorylase ( MTAP ) Die Prematurely of T-Cell Lymphoma

Kadariya, Y., Yin, B., Tang, B., Shinton, S. A., Quinlivan, E. P., Xiang, H., Klein–Szanto, A. J., Al‐Saleem, T., Bassing, C. H., Hardy, R. R., et al. (2009) · Cancer Research · doi:10.1158/0008-5472.can-09-0145 · Cited by 50 · see citing works

Nuclear Magnetic Resonance (NMR)-Based Metabolomics

Keun, H. C., & Athersuch, T. J. (2010) · Methods in molecular biology · doi:10.1007/978-1-61737-985-7_19 · Cited by 38 · see citing works

Statistical integration of 1H NMR and MRS data from different biofluids and tissues enhances recovery of biological information from individuals with HIV-1 infection.

Maher, A. D., Cysique, L., Brew, B., & Rae, C. (2011) · Journal of Proteome Research · doi:10.1021/pr1010263 · Cited by 34 · see citing works

Glutamate signaling through the kainate receptor enhances human immunoglobulin production

Sturgill, J., Mathews, J. A., Scherle, P., & Conrad, D. H. (2011) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2010.11.014 · Cited by 32 · see citing works

Differentiation in the murine B cell lymphoma I.29: individual μ+ clones may be induced by lipopolysaccharide to both IgM secretion and isotype switching

Alberini, C. M., Biassoni, R., Deambrosis, S., Vismara, D., & Sitia, R. (1987) · European Journal of Immunology · doi:10.1002/eji.1830170419 · Cited by 30 · see citing works

The CCPN Metabolomics Project: a fast protocol for metabolite identification by 2D-NMR

Chignola, F., Mari, S., Stevens, T. J., et al. (2011) · Bioinformatics · doi:10.1093/bioinformatics/btr013 · Cited by 28 · see citing works

Effects of hypoxia, anoxia, and endogenous ethanol on thermoregulation in goldfish,Carassius auratus

Rausch, R. N., Crawshaw, L. I., & Wallace, H. L. (2000) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.2000.278.3.r545 · Cited by 25 · see citing works

Uric acid and the immune response

Gersch, M. S., & Johnson, R. J. (2006) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gfl226 · Cited by 22 · see citing works

1H-NMR studies of cerebrospinal fluid: endogenous ethanol in patients with cervical myelopathy

Meshitsuka, S., Morio, Y., Nagashima, H., et al. (2001) · Clinica Chimica Acta · doi:10.1016/s0009-8981(01)00587-3 · Cited by 15 · see citing works

Synthesis and release of deoxycytidine by human B and T lymphoblasts

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Metabolomic Study on Vitamins B1, B2, and PP Supplementation to Improve Serum Metabolic Profiles in Mice under Acute Hypoxia Based on 1H NMR Analysis

Liu, J., Jian-Quan, W. U., Ji-Jun, Y. A. N. G., et al. (2010) · Biomedical and Environmental Sciences · doi:10.1016/s0895-3988(10)60069-4 · Cited by 10 · see citing works

CLINICALLY RELEVANT DEOXYCYTIDINE LEVELS ARE HIGH ENOUGH TO PROFOUNDLY ALTER 9-beta-D-ARABINOFURANOSYLGUANINE CYTOTOXICITY FOR HUMAN T-CELL ACUTE LEUKEMIA CELLS IN VITRO

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Mitochondria in the Regulation of Innate and Adaptive Immunity

Weinberg, S. E., Sena, L. A., & Chandel, N. S. (2015) · Immunity · doi:10.1016/j.immuni.2015.02.002 · Cited by 960 · see citing works

Defective glucose metabolism in polycystic kidney disease identifies a new therapeutic strategy

Rowe, I., Chiaravalli, M., Mannella, V., Ulisse, V., Quilici, G., Pema, M., Song, X. W., Xu, H., Mari, S., Qian, F., et al. (2013) · Nature Medicine · doi:10.1038/nm.3092 · Cited by 503 · see citing works

Glucose-dependent de Novo Lipogenesis in B Lymphocytes

Dufort, F. J., Gumina, M. R., Ta, N. L., Tao, Y., Heyse, S. A., Scott, D. A., Richardson, A. D., Seyfried, T. N., & Chiles, T. C. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m114.551051 · Cited by 160 · see citing works

Metabolic control of the epigenome in systemic Lupus erythematosus

Oaks, Z., & Perl, A. (2014) · Autoimmunity · doi:10.3109/08916934.2013.834495 · Cited by 76 · see citing works

Human 293 Cell Metabolism in Low Glutamine-Supplied Culture: Interpretation of Metabolic Changes through Metabolic Flux Analysis

Nadeau, I., Sabatié, J., Koehl, M., et al. (2000) · Metabolic Engineering · doi:10.1006/mben.2000.0152 · Cited by 50 · see citing works

Therapeutic effect and mechanism of danshensu on coronary heart disease using liquid chromatography combined with mass spectrometry metabolomics

Zhou, P., An, B., Zhang, X., et al. (2022) · Journal of Chromatography B · doi:10.1016/j.jchromb.2022.123400 · Cited by 5 · see citing works

Global Metabolomic Profiling of Mice Brains following Experimental Infection with the Cyst-Forming Toxoplasma gondii

Zhou, C., Zhou, D., Elsheikha, H. M., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0139635 · Cited by 43 · see citing works

Ultra-Performance Liquid Chromatography/Mass Spectrometry-Based Metabolomics for Discovering Potential Biomarkers and Metabolic Pathways of Colorectal Cancer in Mouse Model (ApcMin/+) and Revealing the Effect of Honokiol

Chen, X., Shi, B., Qi, R., Chang, X., & Zheng, H. (2021) · Frontiers in Oncology · doi:10.3389/fonc.2021.671014 · Cited by 7 · see citing works

Dynamics of growth and metabolism controlled by glutamine availability in Chinese hamster ovary cells

Wahrheit, J., Nicolae, A., & Heinzle, E. (2013) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-013-5452-2 · Cited by 49 · see citing works