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Emerging Role of ISG15 in Antiviral Immunity
Open accessAbstract
Cells express a plethora of interferon-stimulated genes (ISGs) in response to viral infection. Among these is ISG15, a ubiquitin-like protein (UBL), that can be covalently attached to both host and viral proteins. Here we review recent advances towards understanding the role and mechanism of ISG15 modification in antiviral defense.
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Cited by
Systematic and Quantitative Assessment of the Ubiquitin-Modified Proteome
Kim, W., Bennett, E. J., Huttlin, E. L., Guo, A., Li, J., Possemato, A., Sowa, M. E., Rad, R., Rush, J., Comb, M. J., et al. (2011) · Molecular Cell · doi:10.1016/j.molcel.2011.08.025 · Cited by 1,613
Interferon-stimulated genes and their antiviral effector functions
Schoggins, J. W., & Rice, C. M. (2011) · Current Opinion in Virology · doi:10.1016/j.coviro.2011.10.008 · Cited by 1,289
The broad-spectrum antiviral functions of IFIT and IFITM proteins
Diamond, M. S., & Farzan, M. (2013) · Nature Reviews Immunology · doi:10.1038/nri3344 · Cited by 849
HIV-1 assembly, budding, and maturation
Sundquist, W. I., & Krausslich, H.-G. (2012) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a006924 · Cited by 814
Interferon-inducible effector mechanisms in cell-autonomous immunity
MacMicking, J. D. (2012) · Nature Reviews Immunology · doi:10.1038/nri3210 · Cited by 579
Metadata
- Authors
- Skaug, B., & Chen, Z. J.
- Venue
- Cell
- Publisher
- Elsevier BV
- Published
- 2010-10
- Volume
- 143
- Issue
- 2
- Pages
- 187-190
- ISSN
- 0092-8674 (ISSN-L)
- OpenAlex
- W1977105782
- Cited by
- 222
- References
- 0
- FWCI
- 8.78
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
