The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.
Interferon-inducible effector mechanisms in cell-autonomous immunity
Open accessAbstract
Interferons (IFNs) induce the expression of hundreds of genes as part of an elaborate antimicrobial programme designed to combat infection in all nucleated cells — a process termed cell-autonomous immunity. As described in this Review, recent genomic and subgenomic analyses have begun to assign functional properties to novel IFN-inducible effector proteins that restrict bacteria, protozoa and viruses in different subcellular compartments and at different stages of the pathogen life cycle. Several newly described host defence factors also participate in canonical oxidative and autophagic pathways by spatially coordinating their activities to enhance microbial killing. Together, these IFN-induced effector networks help to confer vertebrate host resistance to a vast and complex microbial world.
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Activation and evasion of type I interferon responses by SARS-CoV-2
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Asthma Exacerbations: Pathogenesis, Prevention, and Treatment
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Metadata
- Authors
- MacMicking, J. D.
- Venue
- Nature Reviews Immunology
- Published
- 2012-04-25
- Volume
- 12
- Issue
- 5
- Pages
- 367-382
- ISSN
- 1474-1733 (ISSN-L)
- 1474-1741
- OpenAlex
- W2058235794
- Cited by
- 579
- References
- 19
- FWCI
- 2.03
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
