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HSF-1 Regulators DDL-1/2 Link Insulin-like Signaling to Heat-Shock Responses and Modulation of Longevity

Chiang, Wei-Chung, Ching, Tsui-Ting, Lee, Hee Chul, Mousigian, Carol, Hsu, Ao-Lin·2012·Cell
DOI 10.1016/j.cell.2011.12.019PMC PMC3615449
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  • Activation of the master regulator of the heat-shock response, the transcription factor HSF-1, increases longevity and thermotolerance in nematodes.

    “Moreover, activation of the master regulator of the heat-shock response, the transcription factor HSF-1, increases longevity and thermotolerance in nematodes (Chiang et al., 2012; Hsu et al., 2003), while amyloid-binding components can maintain proteostasis during aging and extend lifespan (Alavez et al., 2011).”

    From The Hallmarks of Aging (2013) · cites this paper as Chiang et al., 2012

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Research works printed but not linked: 36

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Metadata

Authors
Chiang, W.-C., Ching, T.-T., Lee, H. C., Mousigian, C., & Hsu, A.-L.
Venue
Cell
Publisher
Elsevier BV
Published
2012-01
Volume
148
Issue
1-2
Pages
322-334
ISSN
0092-8674
DOI
10.1016/j.cell.2011.12.019
PMC
PMC3615449
Cited by
219
References
1
Language
en
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