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Germline P Granules Are Liquid Droplets That Localize by Controlled Dissolution/Condensation

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Natively unfolded proteins: A point where biology waits for physics

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Eukaryotic Stress Granules: The Ins and Outs of Translation

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RNA-Binding Proteins Tia-1 and Tiar Link the Phosphorylation of Eif-2α to the Assembly of Mammalian Stress Granules

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Kinesin Transports RNA

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Stress Granule Assembly Is Mediated by Prion-like Aggregation of TIA-1

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Pleomorphic Ensembles: Formation of Large Clusters Composed of Weakly Interacting Multivalent Molecules

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Smad4 sequestered in SFPQ condensates prevents TGF-β tumor-suppressive signaling

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Functional specificity in biomolecular condensates revealed by genetic complementation

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Assessing amyloid fibrils and amorphous aggregates: A review

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Dynamics in the solid-state: perspectives for the investigation of amyloid aggregates, membrane proteins and soluble protein complexes

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The role of cold shock domain proteins in inflammatory diseases

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Molecular Origin of pH‐Dependent Fibril Formation of a Functional Amyloid

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Computational analysis of candidate prion-like proteins in bacteria and their role

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Binding of NUFIP2 to Roquin promotes recognition and regulation of ICOS mRNA

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Physiologically Important Electrolytes as Regulators of TDP-43 Aggregation and Droplet-Phase Behavior

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Sequence characteristics responsible for protein‐protein interactions in the intrinsically disordered regions of caseins, amelogenins, and small heat‐shock proteins

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Age‐related neurodegenerative diseases

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The expanding world of metabolic enzymes moonlighting as RNA binding proteins

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Targeted modulation of protein liquid–liquid phase separation by evolution of amino-acid sequence

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Biomolecular condensates in cancer biology

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Molecular Investigations of Protein Aggregation in the Pathogenesis of Amyotrophic Lateral Sclerosis

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Graphene Quantum Dots Modulate Stress Granule Assembly and Prevent Abnormal Phase Transition of Fused in Sarcoma Protein

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Heterologous Aggregates Promote De Novo Prion Appearance via More than One Mechanism

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Unmasking the messenger

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Primary transcripts: From the discovery of RNA processing to current concepts of gene expression ‐ Review

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Higher-order assemblies in innate immune and inflammatory signaling: A general principle in cell biology

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Amyotrophic Lateral Sclerosis Modifiers inDrosophilaReveal the Phospholipase D Pathway as a Potential Therapeutic Target

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Application of yeast to studying amyloid and prion diseases

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Subcompartmentalization of polyampholyte species in organelle-like condensates is promoted by charge-pattern mismatch and strong excluded-volume interaction

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Roles of protein arginine methyltransferase 1 (PRMT1) in brain development and disease

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Amyotrophic Lateral Sclerosis Genes in Drosophila melanogaster

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Distinct roles of hnRNPH1 low-complexity domains in splicing and transcription

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Age-dependent aggregation of ribosomal RNA-binding proteins links deterioration in chromatin stability with challenges to proteostasis

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Comparative analyses of vertebrate CPEB proteins define two subfamilies with coordinated yet distinct functions in post-transcriptional gene regulation

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Biomolecular condensation involving the cytoskeleton

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Towards sequence-based principles for protein phase separation predictions

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Comprehensive Protein Interactome Analysis of a Key RNA Helicase: Detection of Novel Stress Granule Proteins

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The Y-Box Binding Protein 1 Suppresses Alzheimer’s Disease Progression in Two Animal Models

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Idiosyncrasies of hnRNP A1-RNA recognition: Can binding mode influence function

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Protein phase separation in mitosis

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Amyloid and Amyloid-Like Aggregates: Diversity and the Term Crisis

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Determinants for intrinsically disordered protein recruitment into phase-separated protein condensates

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Proteostasis and RNA Binding Proteins in Synaptic Plasticity and in the Pathogenesis of Neuropsychiatric Disorders

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DEAD-box ATPases as regulators of biomolecular condensates and membrane-less organelles

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Synaptic control of local translation: the plot thickens with new characters

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An Atypical Tropomyosin in Drosophila with Intermediate Filament-like Properties

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Dynamics of the formation of a hydrogel by a pathogenic amyloid peptide: islet amyloid polypeptide

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Effects of Mutations on the Aggregation Propensity of the Human Prion-Like Protein hnRNPA2B1

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Prion-based nanomaterials and their emerging applications

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Transcriptional control of CBX5 by the RNA-binding proteins RBMX and RBMXL1 maintains chromatin state in myeloid leukemia

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The Alternative Splicing of Cytoplasmic Polyadenylation Element Binding Protein 2 Drives Anoikis Resistance and the Metastasis of Triple Negative Breast Cancer

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Vulnerability of microRNA biogenesis in FTD–ALS

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Prions, amyloids, and RNA: Pieces of a puzzle

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Regulation of nucleolus assembly by non-coding RNA polymerase II transcripts

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Mechanisms of Vertebrate Germ Cell Determination

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Arginine-rich Peptides Can Actively Mediate Liquid-liquid Phase Separation

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Self-Assembly of Spider Silk-Fusion Proteins Comprising Enzymatic and Fluorescence Activity

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A hydrophobic low-complexity region regulates aggregation of the yeast pyruvate kinase Cdc19 into amyloid-like aggregates in vitro

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Order/Disorder in Protein and Peptide‐Based Biomaterials

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Effect of additives on liquid droplets and aggregates of proteins

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Proteomic analysis reveals the direct recruitment of intrinsically disordered regions to stress granules in S. cerevisiae

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Antagonistic roles for Ataxin-2 structured and disordered domains in RNP condensation

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Mechanisms of Non-Vesicular Exchange of Lipids at Membrane Contact Sites: Of Shuttles, Tunnels and, Funnels

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Liquid-Liquid Phase Separation in Nucleation Process of Biomineralization

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Modulation of assembly of TDP-43 low-complexity domain by heparin: From droplets to amyloid fibrils

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Isoxazole Alters Metabolites and Gene Expression, Decreasing Proliferation and Promoting a Neuroendocrine Phenotype in β-Cells

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Hamiltonian Switch Metropolis Monte Carlo Simulations for Improved Conformational Sampling of Intrinsically Disordered Regions Tethered to Ordered Domains of Proteins

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Liquid-liquid phase separation as a major mechanism of plant abiotic stress sensing and responses

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Molecular Mechanisms of Protein Aggregation in ALS-FTD: Focus on TDP-43 and Cellular Protective Responses

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3′UTRs take a long shot in the brain

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Beyond the cytoskeleton: mesoscale assemblies and their function in spatial organization

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Modifiers of solid RNP granules control normal RNP dynamics and mRNA activity in early development

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How do the RNA-binding proteins TDP-43 and FUS relate to amyotrophic lateral sclerosis and frontotemporal degeneration, and to each other?

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A glass menagerie of low complexity sequences

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PRMT1-mediated methylation of the microprocessor-associated proteins regulates microRNA biogenesis

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Periphilin self-association underpins epigenetic silencing by the HUSH complex

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From Prions to Stress Granules: Defining the Compositional Features of Prion-Like Domains That Promote Different Types of Assemblies

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Emerging Roles for Phase Separation of RNA-Binding Proteins in Cellular Pathology of ALS

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Numerical Techniques for Applications of Analytical Theories to Sequence-Dependent Phase Separations of Intrinsically Disordered Proteins

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Phase separation in fungi

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Characterization of Soft Amyloid Cores in Human Prion-Like Proteins

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Liquid‐Liquid Phase Separation Promotes Protein Aggregation and Its Implications in Ferroptosis in Parkinson’s Disease Dementia

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RNA granules in flux: dynamics to balance physiology and pathology

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Characterization of DNA binding and pairing activities associated with the native SFPQ·NONO DNA repair protein complex

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Perspective on SOD1 mediated toxicity in Amyotrophic Lateral Sclerosis

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Targeting Tyro3 ameliorates a model of PGRN-mutant FTLD-TDP via tau-mediated synaptic pathology

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FMRP regulates presynaptic localization of neuronal voltage gated calcium channels

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Peptide-based Interaction Proteomics

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Cryo-EM structure of the nonameric CsgG-CsgF complex and its implications for controlling curli biogenesis in Enterobacteriaceae

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Advances in the phase separation-organized membraneless organelles in cells: a narrative review

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The adhesive skin exudate of Notaden bennetti frogs (Anura: Limnodynastidae) has similarities to the prey capture glue of Euperipatoides sp. velvet worms (Onychophora: Peripatopsidae)

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The role of FLI-1-EWS, a fusion gene reciprocal to EWS-FLI-1, in Ewing sarcoma

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Jim's View: Is the Golgi stack a phase‐separated liquid crystal?

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Self-assembly of promoter DNA and RNA Pol II machinery into transcriptionally active biomolecular condensates

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Long non-coding RNAs: roles in cellular stress responses and epigenetic mechanisms regulating chromatin

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Phase Separation and Aggregation of α‐Synuclein Diverge at Different Salt Conditions

Sternke‐Hoffmann, R., Sun, X., Menzel, A., Pinto, M. D. S., Venclovaitė, U., Wördehoff, M. M., Hoyer, W., Zheng, W., & Luo, J. (2024) · Advanced Science · doi:10.1002/advs.202308279 · Cited by 30

Translation and silencing in RNA granules: a tale of sand grains

Pimentel, J. N., & Boccaccio, G. L. (2014) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2014.00068 · Cited by 30

SCD6 induces ribonucleoprotein granule formation in trypanosomes in a translation-independent manner, regulated by its Lsm and RGG domains

Krüger, T., Hofweber, M., & Krämer, S. (2013) · Molecular Biology of the Cell · doi:10.1091/mbc.e13-01-0068 · Cited by 30

Nucleoli and Stress Granules: Connecting Distant Relatives

Mahboubi, H., & Stochaj, U. (2014) · Traffic · doi:10.1111/tra.12191 · Cited by 33

The acute myeloid leukemia‐associated Nucleophosmin 1 gene mutations dictate amyloidogenicity of the C‐terminal domain

Manna, S. L., Scognamiglio, P. L., Roviello, V., Borbone, F., Florio, D., Natale, C. D., Bigi, A., Cecchi, C., Cascella, R., Giannini, C., et al. (2019) · FEBS Journal · doi:10.1111/febs.14815 · Cited by 30

Exploiting Replication Stress as a Novel Therapeutic Intervention

Martin, J. C., Hoegel, T. J., Lynch, M. L., Woloszynska‐Read, A., Melendy, T., & Ohm, J. E. (2020) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-20-0651 · Cited by 32

Altered Phase Separation and Cellular Impact in C9orf72-Linked ALS/FTD

Solomon, D. A., Smikle, R., Reid, M. J., & Mizielinska, S. (2021) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2021.664151 · Cited by 33

Identification of a Region in the Common Amino-terminal Domain of Hendra Virus P, V, and W Proteins Responsible for Phase Transition and Amyloid Formation

Salladini, E., Gondelaud, F., Nilsson, J. F., Pesce, G., Bignon, C., Murrali, M. G., Fabre, R., Pierattelli, R., Kajava, A. V., Horvat, B., et al. (2021) · Biomolecules · doi:10.3390/biom11091324 · Cited by 30

Cell-free Formation of RNA Granules: Bound RNAs Identify Features and Components of Cellular Assemblies

Han, T. W., Kato, M., Xie, S., Wu, L. C., Mirzaei, H., Pei, J., Chen, M., Xie, Y., Allen, J. D., Xiao, G., et al. (2012) · Cell · doi:10.1016/j.cell.2012.04.016 · Cited by 773

Getting RNA and Protein in Phase

Weber, S. C., & Brangwynne, C. P. (2012) · Cell · doi:10.1016/j.cell.2012.05.022 · Cited by 468

Intracellular production of hydrogels and synthetic RNA granules by multivalent molecular interactions

Nakamura, H., Lee, A. A., Afshar, A. S., Watanabe, S., Rho, E., Razavi, S., Suarez, A., Lin, Y., Tanigawa, M., Huang, B., et al. (2017) · Nature Materials · doi:10.1038/nmat5006 · Cited by 131

Secrets of RNA granules

Baker, M. (2012) · Nature Methods · doi:10.1038/nmeth.2090 · Cited by 2

Formation of synthetic RNA protein granules using engineered phage-coat-protein -RNA complexes

Granik, N., Katz, N., Willinger, O., Goldberg, S., & Amit, R. (2022) · Nature Communications · doi:10.1038/s41467-022-34644-4 · Cited by 10