Regulation of the Hippo-YAP Pathway by G-Protein-Coupled Receptor Signaling

Yu, Fa-Xing, Zhao, Bin, Panupinthu, Nattapon, Jewell, Jenna L., Lian, Ian, Wang, Lloyd H., Zhao, Jiagang, Yuan, Haixin +5 more·2012·Cell

DOI 10.1016/j.cell.2012.06.037

Cited by (1,002)

Items 301–400 of 1,002

Phosphorylation of the Hippo Pathway Component AMOTL2 by the mTORC2 Kinase Promotes YAP Signaling, Resulting in Enhanced Glioblastoma Growth and Invasiveness
Nicholas Artinian, Cheri Cloninger, Brent Holmes, Angelica Benavides-Serrato, Tariq Bashir, Joseph Gera · 2015 · Journal of Biological Chemistry
Oncogenic signaling pathways associated with immune evasion and resistance to immune checkpoint inhibitors in cancer
Yoshie Kobayashi, Seung‐Oe Lim, Hirohito Yamaguchi · 2019 · Seminars in Cancer Biology
The Hippo signal transduction network in skeletal and cardiac muscle
Wackerhage, Henning, Del Re, Dominic P., Judson, Robert N., Sudol, Marius, Sadoshima, Junichi · 2014 · Science Signaling
Multifaceted regulation and functions of YAP/TAZ in tumors (Review)
Huirong Liu, Suya Du, Tiantian Lei, Hailian Wang, Xia He, Rongsheng Tong, Yi Wang · 2018 · Oncology Reports
The Hippo Tumor Suppressor Pathway (YAP/TAZ/TEAD/MST/LATS) and EGFR-RAS-RAF-MEK in cancer metastasis
Mohammad Reza Zinatizadeh, Seyed Rouhollah Miri, Peyman Kheirandish Zarandi, Ghanbar Mahmoodi Chalbatani, Catarina Rapôso, Hamid Reza Mirzaei, Mohammad Esmaeil Akbari, Habibollah Mahmoodzadeh · 2019 · Genes & Diseases
LATS suppresses mTORC1 activity to directly coordinate Hippo and mTORC1 pathways in growth control
Wenjian Gan, Xiaoming Dai, Xiangpeng Dai, Jun Xie, Shasha Yin, Junjie Zhu, Chen Wang, Yuchen Liu, Jianping Guo, Min Wang et al. · 2020 · Nature Cell Biology
Regulation of Hippo-YAP signaling by insulin-like growth factor-1 receptor in the tumorigenesis of diffuse large B-cell lymphoma
Xiangxiang Zhou, Na Chen, Hongzhi Xu, Xiaoming Zhou, Jianhong Wang, Xiaosheng Fang, Ya Zhang, Ying Li, Juan Yang, Xin Wang · 2020 · Journal of Hematology & Oncology
The two sides of Hippo pathway in cancer
Fulong Li, Kun‐Liang Guan · 2021 · Seminars in Cancer Biology
The Hippo pathway is controlled by Angiotensin II signaling and its reactivation induces apoptosis in podocytes
Dirk Oliver Wennmann, Beate Vollenbröker, A K Eckart, Jakob Bonse, F Erdmann, Dirk Andreas Wolters, L K Schenk, Ulf Schulze, Joachim Kremerskothen, Thomas Weide et al. · 2014 · Cell Death and Disease
Neuro-Mesenchymal Interaction Mediated by a β2-Adrenergic Nerve Growth Factor Feedforward Loop Promotes Colorectal Cancer Progression
Hiroki Kobayashi, Tadashi Iida, Yosuke Ochiai, Ermanno Malagola, Xiaofei Zhi, Ruth Aroon White, Jin Qian, Feijing Wu, Quin T. Waterbury, Ru‐Hong Tu et al. · 2024 · Cancer Discovery
YAP and TAZ Take Center Stage in Cancer
Kun Zhang, Hai-Xia Qi, Zhimei Hu, Yanan Chang, Zhemin Shi, Xiaohui Han, Yawei Han, Ruixue Zhang, Zhen Zhang, Ting Chen et al. · 2015 · Biochemistry
The Hippo and Wnt signalling pathways: crosstalk during neoplastic progression in gastrointestinal tissue
Nianshuang Li, Nonghua Lü, Chuan Xie · 2019 · FEBS Journal
Hippo and TGF-β interplay in the lung field
Akira Saito, Takeshi Nagase · 2015 · American Journal of Physiology-Lung Cellular and Molecular Physiology
YAP-mediated regulation of the chondrogenic phenotype in response to matrix elasticity
Weiliang Zhong, Ying Li, Linan Li, Weiguo Zhang, Shouyu Wang, Xifu Zheng · 2013 · Journal of Molecular Histology
Endothelial Cell Mechanotransduction in the Dynamic Vascular Environment
Frank W. Charbonier, Maedeh Zamani, Ngan Fong Huang · 2018 · Advanced Biosystems
S-nitrosylation-mediated coupling of G-protein alpha-2 with CXCR5 induces Hippo/YAP-dependent diabetes-accelerated atherosclerosis
Menglin Chao, Shanshan Luo, Chao Zhang, Xuechun Zhou, Miao Zhou, Junyan Wang, Chuiyu Kong, Jiyu Chen, Zhe Lin, Xin Tang et al. · 2021 · Nature Communications
Cross-talk between Wnt/β-catenin and Hippo signaling pathways: a brief review
Minseong Kim, Eek‐hoon Jho · 2014 · BMB Reports
The Tyrosine Phosphatase PTPN14 Is a Negative Regulator of YAP Activity
Chrysiis Michaloglou, Waltraut Lehmann, Typhaine Martin, Clara Delaunay, Andreas Hueber, Louise Barys, Honglin Niu, Éric Billy, Markus Wartmann, Moriko Ito et al. · 2013 · PLoS ONE
Reciprocal Crosstalk Between YAP1/Hippo Pathway and the p53 Family Proteins: Mechanisms and Outcomes in Cancer
Nitin Raj, Rakesh Bam · 2019 · Frontiers in Cell and Developmental Biology
Hippo signaling pathway and respiratory diseases
Weifeng Tang, Min Li, Xiaoting Yangzhong, Xifeng Zhang, Anju Zu, Yunjiao Hou, Lin Li, Shibo Sun · 2022 · Cell Death Discovery
ENO1 promotes liver carcinogenesis through YAP1-dependent arachidonic acid metabolism
Linchong Sun, Caixia Suo, Tong Zhang, Shengqi Shen, Xuemei Gu, Shiqiao Qiu, Pinggen Zhang, Haoran Wei, Wenhao Ma, Ronghui Yan et al. · 2023 · Nature Chemical Biology
Endothelial YAP/TAZ Signaling in Angiogenesis and Tumor Vasculature
Hooglugt, Aukie, van der Stoel, Miesje M., Boon, Reinier A., Huveneers, Stephan · 2021 · Frontiers in Oncology
The Hippo Signaling Pathway in Drug Resistance in Cancer
Zeng, Renya, Dong, Jixin · 2021 · Cancers
The Hippo pathway effector TAZ induces TEAD-dependent liver inflammation and tumors
Thijs J. Hagenbeek, Joshua D. Webster, Noelyn M. Kljavin, Matthew T. Chang, Trang Pham, Ho-June Lee, Christiaan N. Klijn, Allen G. Cai, Klára Tótpál, Buvana Ravishankar et al. · 2018 · Science Signaling
Cancer cell adaptation to hypoxia involves a HIF‐GPRC5A‐YAP axis
Alexander Greenhough, Clare Bagley, Kate J. Heesom, David Gurevich, David Michael Gay, Mark Bond, T J Collard, C Paraskeva, Paul B. Martin, Owen James Sansom et al. · 2018 · EMBO Molecular Medicine
Framework to function: mechanosensitive regulators of gene transcription
Finch-Edmondson, Megan, Sudol, Marius · 2016 · Cellular & Molecular Biology Letters
Transcription factor AP-2γ induces early Cdx2 expression and represses HIPPO signaling to specify the trophectoderm lineage
Zubing Cao, Timothy S. Carey, Avishek Ganguly, CATHERINE A. WILSON, Soumen Paul, Jason G. Knott · 2015 · Development
The Hippo Pathway Effectors YAP/TAZ-TEAD Oncoproteins as Emerging Therapeutic Targets in the Tumor Microenvironment
Reza Bayat Mokhtari, Neda Ashayeri, Leili Baghaie, Manpreet Sambi, Kosar Satari, Narges Baluch, Dmitriy A. Bosykh, Myron R. Szewczuk, Sayan Chakraborty · 2023 · Cancers
Antiproliferative and Antimigratory Effects of a Novel YAP–TEAD Interaction Inhibitor Identified Using in Silico Molecular Docking
Sarah Ann Smith, Richard Barry Sessions, Deborah K. Shoemark, Christopher Williams, Reza Ebrahimighaei, Madeleine C. McNeill, Matthew P. Crump, Tristan R. McKay, Gemma Harris, Andrew C. Newby et al. · 2019 · Journal of Medicinal Chemistry
Emerging role of Hippo pathway in gastric and other gastrointestinal cancers
Wei Kang · 2016 · World Journal of Gastroenterology
The Hippo signaling pathway provides novel anti-cancer drug targets
June Sung Bae, Sun Mi Kim, Ho Lee · 2016 · Oncotarget
The posttranslational modifications of Hippo-YAP pathway in cancer
Fangjie Yan, Meijia Qian, Qiaojun He, Hong Zhu, Bo Yang · 2019 · Biochimica et Biophysica Acta (BBA) - General Subjects
Geranylgeranylation signals to the Hippo pathway for breast cancer cell proliferation and migration
Wenyi Mi, Qiong Lin, Chandra Childress, Marius Sudol, Janet D. Robishaw, Catherine H. Berlot, Mohsen M. Shabahang, Wannian Yang · 2014 · Oncogene
Angiomotin decreases lung cancer progression by sequestering oncogenic YAP/TAZ and decreasing Cyr61 expression
Y-L Hsu, J-Y. Hung, S. H. Chou, M.-Y. Huang, M-J Tsai, Y S Lin, S-Y Chiang, Y-W Ho, C-Y Wu, P-L Kuo · 2014 · Oncogene
Targeting the Hippo Signaling Pathway for Tissue Regeneration and Cancer Therapy
Wen Chun Juan, Wanjin Hong · 2016 · Genes
A reciprocal regulatory loop between TAZ/YAP and G-protein Gαs regulates Schwann cell proliferation and myelination
Yaqi Deng, Lai Man Natalie Wu, Shujun Bai, Chuntao Zhao, Haibo Wang, Jincheng Wang, Lingli Xu, Masahide Sakabe, Wenhao Zhou, Mei Xin et al. · 2017 · Nature Communications
Deregulation of Hippo–TAZ pathway during renal injury confers a fibrotic maladaptive phenotype
Sandybell Anorga, Jessica M. Overstreet, Lucas L. Falke, Jiaqi Tang, Roel Goldschmeding, Paul J. Higgins, Rohan Samarakoon · 2018 · The FASEB Journal
The Hippo Pathway Regulates Caveolae Expression and Mediates Flow Response via Caveolae
Valentina Rausch, Jonathan R. Bostrom, Jiwon Park, Isabel Ribeiro Bravo, Yi Feng, David C. Hay, Brian A. Link, Carsten Gram Hansen · 2018 · Current Biology
The Hippo Pathway in Prostate Cancer
Omar Salem, Carsten Gram Hansen · 2019 · Cells
Angiogenesis in gynecological cancers and the options for anti-angiogenesis therapy
Bahar Yetkin-Arik, Arnoud W. Kastelein, Ingeborg Klaassen, Charlotte H. J. R. Jansen, Yani P. Latul, Miloš Vittori, Aydan Bırı, Korhan Kahraman, Arjan W. Griffioen, Frédéric C. Amant et al. · 2020 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
Deacetylation of tumor-suppressor MST1 in Hippo pathway induces its degradation through HBXIP-elevated HDAC6 in promotion of breast cancer growth
Lu-Shen Li, Runping Fang, Baotang Liu, Hui Shi, Yaming Wang, Wenjing Zhang, Xiaoqing Zhang, L Ye · 2015 · Oncogene
Two distinct trophectoderm lineage stem cells from human pluripotent stem cells
Adam Mischler, Victoria Karakis, Jessica Mahinthakumar, Celeste K. Carberry, Adriana San‐Miguel, Julia E. Rager, Rebecca C. Fry, Balaji M. Rao · 2021 · Journal of Biological Chemistry
The Hippo pathway in colorectal cancer
Piotr Wierzbicki, Agnieszka Rybarczyk · 2015 · Folia Histochemica et Cytobiologica
Concerted localization-resets precede YAP-dependent transcription
John M. Franklin, Rajarshi P. Ghosh, Quanming Shi, Michael P. Reddick, Jan Liphardt · 2020 · Nature Communications
Mechanotransduction at the Plasma Membrane-Cytoskeleton Interface
Iván P. Uray, Karen Uray · 2021 · International Journal of Molecular Sciences
New insights into the ambivalent role of YAP/TAZ in human cancers
Juan Luo, Liang Deng, Hailin Zou, Yibo Guo, Tongyu Tong, Mingli Huang, Gengqiang Ling, Peng Li · 2023 · Journal of Experimental & Clinical Cancer Research
Atheroprotective laminar flow inhibits Hippo pathway effector YAP in endothelial cells
Suowen Xu, Marina Koroleva, Meimei Yin, Zheng Gen Jin · 2016 · Translational research
Irbesartan overcomes gemcitabine resistance in pancreatic cancer by suppressing stemness and iron metabolism via inhibition of the Hippo/YAP1/c-Jun axis
Tianxing Zhou, Yongjie Xie, Xupeng Hou, Weiwei Bai, Xueyang Li, Ziyun Liu, Quan Man, Jingyan Sun, Danqi Fu, Jingrui Yan et al. · 2023 · Journal of Experimental & Clinical Cancer Research
The MST1/2-SAV1 complex of the Hippo pathway promotes ciliogenesis
Miju Kim, Minchul Kim, Mi‐Sun Lee, Cheol‐Hee Kim, Dae‐Sik Lim · 2014 · Nature Communications
Kaposi sarcoma-associated herpesvirus promotes tumorigenesis by modulating the Hippo pathway
Gao Liu, Fa‐Xing Yu, Young Chul Kim, Zhipeng Meng, Julián Naipauer, David J. Looney, Xiangguo Liu, Jorge Silvio Gutkind, Enrique A. Mesri, K-L Guan · 2014 · Oncogene
Par‐ aPKC ‐dependent and ‐independent mechanisms cooperatively control cell polarity, Hippo signaling, and cell positioning in 16‐cell stage mouse embryos
Yoshikazu Hirate, Shino Hirahara, Ken-ichi Inoue, Hiroshi Kiyonari, Hiroshi Niwa, Hiroshi Sasaki · 2015 · Development Growth & Differentiation
Molecular Pathways: Hippo Signaling, a Critical Tumor Suppressor
Ana Sebio, Heinz‐Josef Lenz · 2015 · Clinical Cancer Research
Understanding Membrane Protein Drug Targets in Computational Perspective
Jianting Gong, Yongbing Chen, Feng Pu, Pingping Sun, Fei He, Li Zhang, Yanwen Li, Zhiqiang Ma, Han Wang · 2018 · Current Drug Targets
CD44 acts through RhoA to regulate YAP signaling
Yuchen Zhang, Hongwei Xia, Xiaojun Ge, Qingjuan Chen, Dandan Yuan, Qi Chen, Weibing Leng, Liang Chen, Qiulin Tang, Feng Bi · 2014 · Cellular Signalling
Hippo–YAP and mTOR pathways collaborate to regulate organ size
Alfred Csibi, John Blenis · 2012 · Nature Cell Biology
Hippo-YAP/TAZ signaling in angiogenesis
Jeong Ae Park, Young‐Guen Kwon · 2018 · BMB Reports
LIM-domain protein AJUBA suppresses malignant mesothelioma cell proliferation via Hippo signaling cascade
Ichidai Tanaka, Hiroyuki Osada, Makiko Fujii, A Fukatsu, Toyoaki Hida, Yoshitsugu Horio, Yutaka Kondo, Ayuko Sato, Yoshinori Hasegawa, Tohru Tsujimura et al. · 2013 · Oncogene
Regulation of the Hippo pathway in cancer biology
Sungho Moon, So Yeon Park, Hyun Woo Park · 2018 · Cellular and Molecular Life Sciences
Role of RhoA and Rho-associated kinase in phenotypic switching of vascular smooth muscle cells: Implications for vascular function
Tedy Sawma, Abdullah A. Shaito, Nicolas Najm, Munir Sidani, Alexander Nikolaevich Orekhov, Ahmed Fawzy EL‐Yazbi, Rabah Iratni, Ali Hussein Eid · 2022 · Atherosclerosis
Hippo Pathway in Mammalian Adaptive Immune System
Takayoshi Yamauchi, Toshiro Moroishi · 2019 · Cells
New insights into posttranslational modifications of Hippo pathway in carcinogenesis and therapeutics
Mingjing He, Zhuan Zhou, Anil A. Shah, Yang Hong, Qianming Chen, Yong Wan · 2016 · Cell Division
YAP/TAZ Activation Drives Uveal Melanoma Initiation and Progression
Huapeng Li, Qi Li, Kyvan Dang, Shan Ma, Jennifer L. Cotton, Sun Yang, Lihua Julie Zhu, APRIL C. DENG, Yicktung Tony Ip, Randy L. Johnson et al. · 2019 · Cell Reports
The Hippo Pathway as a Driver of Select Human Cancers
Aishwarya Kulkarni, Matthew T. Chang, Joseph H.A. Vissers, Anwesha Dey, Kieran F. Harvey · 2020 · Trends in cancer
The role of the Hippo pathway in the pathogenesis of inflammatory bowel disease
Zhuo Xie, Ying Wang, Guang Yang, Jing Han, Liguo Zhu, Li Li, Shenghong Zhang · 2021 · Cell Death and Disease
The history and regulatory mechanism of the Hippo pathway
Wantae Kim, Eek‐hoon Jho · 2018 · BMB Reports
Loss of Mob1a/b in mice results in chondrodysplasia due to YAP1/TAZ-TEAD-dependent repression of SOX9
Hiroki Goto, Miki Nishio, Yoko To, Tatsuya Oishi, Yosuke Miyachi, Tomohiko Maehama, Hiroshi Nishina, Haruhiko Akiyama, Tak W. Mak, Yuma Makii et al. · 2018 · Development
PTEN lipid phosphatase inactivation links the hippo and PI3K/Akt pathways to induce gastric tumorigenesis
Wen-ting Xu, Zhen Yang, C. Xie, Yin Zhu, X. Shu, Zhe Zhang, Nian-Shuang Li, Na Chai, Song Zhang, Kai-Chun Wu et al. · 2018 · Journal of experimental & clinical cancer research : CR
A gain-of-functional screen identifies the Hippo pathway as a central mediator of receptor tyrosine kinases during tumorigenesis
Taha Azad, Kazem Nouri, Helena J. Janse van Rensburg, Sarah M. Maritan, Liqing Wu, Yawei Hao, Tess Montminy, Jihang Yu, Prem Khanal, Lois M. Mulligan et al. · 2019 · Oncogene
Secreted stromal protein ISLR promotes intestinal regeneration by suppressing epithelial Hippo signaling
Jiuzhi Xu, Yang Tang, Xiaole Sheng, Yuhua Tian, Min Deng, Sujuan Du, Cong Lv, Guili Li, Yuwei Pan, Yongli Song et al. · 2020 · The EMBO Journal
YAP activates the Hippo pathway in a negative feedback loop
Xiaoming Dai, Huan Liu, Shuying Shen, Xiaocan Guo, Huan Yan, Xinyan Ji, Li Li, Jun Huang, Xin‐Hua Feng, Bin Zhao · 2015 · Cell Research
The CalcR-PKA-Yap1 Axis Is Critical for Maintaining Quiescence in Muscle Stem Cells
Lidan Zhang, Yu-taro Noguchi, Hiroyuki Nakayama, Takayuki Kaji, Kazutake Tsujikawa, Madoka Ikemoto‐Uezumi, Akiyoshi Uezumi, Yoshiaki Okada, Takefumi Doi, Shuichi Watanabe et al. · 2019 · Cell Reports
The Hippo Pathway and Viral Infections
Zhilong Wang, Wanhang Lu, Yiling Zhang, Feng Zou, Zhigang Jin, Tiejun Zhao · 2020 · Frontiers in Microbiology
PI3K functions as a hub in mechanotransduction
Mickaël Di‐Luoffo, Zacchari Ben Meriem, Pauline M. Lefebvre, Morgan Delarue, Julie Guillermet‐Guibert · 2021 · Trends in Biochemical Sciences
Cadherin signaling: keeping cells in touch
Olga Klezovitch, Valeri I. Vasioukhin · 2015 · F1000Research
The Hippo-Salvador signaling pathway regulates renal tubulointerstitial fibrosis
Eunjeong Seo, Wan‐Young Kim, Jeongmi Hur, Hanbyul Kim, Sun Ah Nam, Arum Choi, Yumi Kim, Sang Hee Park, Chaeuk Chung, Jin Kim et al. · 2016 · Scientific Reports
Deregulated Lysophosphatidic Acid Metabolism and Signaling in Liver Cancer
Eleanna Kaffe, Christiana Magkrioti, Vassilis Aidinis · 2019 · Cancers
Recent Advances of the Hippo/YAP Signaling Pathway in Brain Development and Glioma
Taohui Ouyang, Wei Meng, Meihua Li, Tao Hong, Na Zhang · 2019 · Cellular and Molecular Neurobiology
YAP and TAZ protect against white adipocyte cell death during obesity
Lei Wang, Shengpeng Wang, Yue Xi Shi, Rui Li, Stefan Günther, Yu Ting Ong, Michael Potente, Zuyi Yuan, Enqi Liu, Stefan Offermanns · 2020 · Nature Communications
Gαs–Protein Kinase A (PKA) Pathway Signalopathies: The Emerging Genetic Landscape and Therapeutic Potential of Human Diseases Driven by Aberrant Gαs-PKA Signaling
Dana J. Ramms, Francesco Raimondi, Nadia Arang, Friedrich W. Herberg, Susan Serota Taylor, Jorge Silvio Gutkind · 2021 · Pharmacological Reviews
A Review: Molecular Aberrations within Hippo Signaling in Bone and Soft-Tissue Sarcomas
Michael D. Deel, Jing Li, Lisa E.S. Crose, Corinne Mary Linardic · 2015 · Frontiers in Oncology
HDL activation of endothelial sphingosine-1-phosphate receptor-1 (S1P1) promotes regeneration and suppresses fibrosis in the liver
Bi‐Sen Ding, Catherine H. Liu, Yue Sun, Yutian Chen, Steven L. Swendeman, Bongnam Jung, Deebly Chavez, Zhongwei Cao, Christina Christoffersen, Lars B. Nielsen et al. · 2016 · JCI Insight
Deubiquitinase YOD1 potentiates YAP/TAZ activities through enhancing ITCH stability
Youngeun Kim, Wantae Kim, Yonghee Song, Jeong‐Rae Kim, Kyungjoo Cho, Hyuk Moon, Simon Weonsang Ro, Eunjeong Seo, Yeon‐Mi Ryu, Seung‐Jae Myung et al. · 2017 · Proceedings of the National Academy of Sciences
Regulation of follicle growth through hormonal factors and mechanical cues mediated by Hippo signaling pathway
Ikko Kawashima, Kazuhiro Kawamura · 2017 · Systems Biology in Reproductive Medicine
The Ambivalent Function of YAP in Apoptosis and Cancer
Xianbin Zhang, Ahmed Abdelrahman, Brigitte Vollmar, Dietmar Zechner · 2018 · International Journal of Molecular Sciences
Hippo Gains Weight: Added Insights and Complexity to Pathway Control
Leonie Enderle, Helen McNeill · 2013 · Science Signaling
Transcriptome analysis of tetraploid cells identifies cyclin D2 as a facilitator of adaptation to genome doubling in the presence of p53
Tamara Potapova, Christopher W. Seidel, Andrew Box, Giulia Irene Rancati, Rong Li · 2016 · Molecular Biology of the Cell
Biomechanical relationships between the corneal endothelium and Descemet's membrane
Maryam Ali, Vijay Krishna Raghunathan, Jennifer Y. Li, Christopher John Murphy, Sara M. Thomasy · 2016 · Experimental Eye Research
The polycystic ovary syndrome-associated gene Yap1 is regulated by gonadotropins and sex steroid hormones in hyperandrogenism-induced oligo-ovulation in mouse
Shu‐Yan Ji, Xiaoman Liu, Bo-Tai Li, Yinli Zhang, Hongbin Liu, Yuchao Zhang, Zi‐Jiang Chen, Junping Liu, Heng‐Yu Fan · 2017 · Molecular Human Reproduction
S1P Stimulates Proliferation by Upregulating CTGF Expression through S1PR2-Mediated YAP Activation
Jung‐Chien Cheng, Evan Y. Wang, Yuyin Yi, Avinash Thakur, Shu‐Huei Tsai, Pamela A. Hoodless · 2018 · Molecular Cancer Research
Hippo/YAP pathway for targeted therapy
Emanuela Felley‐Bosco, Rolf Arno Stahel · 2014 · Europe PMC (PubMed Central)
Loss of VGLL4 suppresses tumor PD‐L1 expression and immune evasion
Ailing Wu, Qingzhe Wu, Yujie Deng, Yuning Liu, Jinqiu Lu, Liansheng Liu, Xiaoling Li, Cheng Lin Liao, Bin Zhao, Hai Xin Song · 2018 · The EMBO Journal
β-arrestin1/YAP/mutant p53 complexes orchestrate the endothelin A receptor signaling in high-grade serous ovarian cancer
Piera Tocci, Roberta Cianfrocca, Valeriana Di Castro, Laura Rosanò, Andrea Sacconi, Sara Donzelli, Silvia Bonfiglio, Gabriele Bucci, Enrico Vizza, Gabriella Ferrandina et al. · 2019 · Nature Communications
Hepatic Hippo signaling inhibits development of hepatocellular carcinoma
Yu-Chen Liu, Xiao-Hui L. Wang, Ying-Zi Yang · 2020 · Clinical and Molecular Hepatology
Evolutionary and Molecular Facts Link the WWC Protein Family to Hippo Signaling
Dirk Oliver Wennmann, Jürgen Schmitz, Michael C. Wehr, Michael P. Krahn, Nora Koschmal, Sascha Gromnitza, Ulf Schulze, Thomas Weide, Anil K. Chekuri, Boris V. Skryabin et al. · 2014 · Molecular Biology and Evolution
Implications of Nonphysiological Ovarian Primordial Follicle Activation for Fertility Preservation
Johanne Grosbois, Melody Devos, Isabelle Demeestere · 2020 · Endocrine Reviews
Mechanical Feed-Forward Loops Contribute to Idiopathic Pulmonary Fibrosis
M.A.T. Freeberg, Apostolos Perelas, Jane K. Rebman, Richard P. Phipps, Thomas H. Thatcher, Patricia J. Sime · 2020 · American Journal Of Pathology
EGFR Regulates the Hippo pathway by promoting the tyrosine phosphorylation of MOB1
Toshinori Ando, Nadia Arang, Zhiyong Wang, Daniela Elena Costea, Xiaodong Feng, Yusuke Goto, Hiroki Izumi, Mara Gilardi, Kazuyo Ando, Jorge Silvio Gutkind · 2021 · Communications Biology
The role of angiomotin phosphorylation in the Hippo pathway during preimplantation mouse development
Yoshikazu Hirate, Hiroshi Sasaki · 2014 · Tissue Barriers
Actin Cytoskeleton Regulates Hippo Signaling
Pradeep Reddy, Masashi Deguchi, Yuan Cheng, Aaron J.W. Hsueh · 2013 · PLoS ONE
Hippo pathway in mammary gland development and breast cancer
Peiguo Shi, Jing Chun Feng, Ceshi Chen · 2014 · Acta Biochimica et Biophysica Sinica