Quantitative Analysis of Hsp90-Client Interactions Reveals Principles of Substrate Recognition
Taipale, Mikko, Krykbaeva, Irina, Koeva, Martina, Kayatekin, Can, Westover, Kenneth D., Karras, Georgios I., Lindquist, Susan·2012·Cell
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- Additional file 3 of AFP-HSP90 mediated MYC/MET activation promotes tumor progression in hepatocellular carcinoma and gastric cancersLin, Ziqi, Rulu Pan, Liyue Wu, Fangsheng Zhu, Fang, Qiwei, Kwok, Hang Fai, Xincheng Lu · 2024 · Figshare
- Additional file 1 of AFP-HSP90 mediated MYC/MET activation promotes tumor progression in hepatocellular carcinoma and gastric cancersLin, Ziqi, Rulu Pan, Liyue Wu, Fangsheng Zhu, Fang, Qiwei, Kwok, Hang Fai, Xincheng Lu · 2024 · Figshare
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- Structural basis for the folding of PINK1 by the HSP90–CDC37 chaperone complexKei Okatsu, H Yamamoto, Akinori Okamoto, Simon Goto, Yumiko Nishimoto, Yukihiko Sugita, Takeshi Noda, Shuya Fukai · 2026 · eLife
- Structural basis for the folding of PINK1 by the HSP90–CDC37 chaperone complexKei Okatsu, H Yamamoto, Akinori Okamoto, Simon Goto, Yumiko Nishimoto, Yukihiko Sugita, Takeshi Noda, Shuya Fukai · 2026 · eLife
- Transmembrane effector substrates of type IV secretion systems: mechanisms of secretion and insertion into host cell membranesSarah-Maria Trenz, Ann-Kathrin Kuwertz, Josua Carl, Samuel Wagner · 2026 · microLife
- Comparative analysis of the impact of Heat shock protein 90 kDa or Cdc37 mutation on the yeast proteomeErick I. Rios, Jill L. Johnson · 2026 · Cell Stress and Chaperones
- A three generation family with VACTERL association is found to have a rare form of diamond-blackfan anaemiaIryna Leshchyns’ka, Debjani Das, Victoria C. O׳Reilly, Alena Sipka, Kavitha R. Iyer, Dimuthu Alankarage, Emma M. Rath, Akshita Kumar, Beth A. Kurt, Maria E. Voydanoff et al. · 2026 · European Journal of Human Genetics
- Heat shock protein Gp96 (Grp94) in malaria: functional insights at the host-parasite interface and therapeutic perspectivesDjibaba DJOUMOI, Abou Abdallah Malick Diouara, Mamadou Diop, Cheikh Momar Nguer, Babacar Mbengué, Fatou Thiam · 2026 · Frontiers in Cell and Developmental Biology
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- Étude de l’infection du système nerveux central par le virus de la rougeoleJérémy Welsch · 2016
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- NFYA regulates two sequential genome-wide transcriptional activation events during oocyte to embryo transitionQianying Yang, Shan Jiang, Boyan Wang, Yi Zhang · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- Identification of APOBEC-Associated Frequent Mutations and Characterization of FGFR3-Driven Signaling Pathways in Bladder CancerMingjun Shi · 2019
- Functional characterization of the TRRAP pseudokinase and its chaperone TTT during transcriptional regulation in colorectal cancerDylane Detilleux · 2018
- Etude des principes d’assemblage et de maturation des kinases de la famille des PIKKs chez Schizosaccharomyces pombeDamien Toullec · 2020 · theses.fr (ABES)
- Study of the effect of HSP90 inhibitors in the treatment of T-ALL and B-ALL, by suppressing the LCK and LYN signaling pathwaysRony Mshaik · 2021
- The stress protein GRP94, complement C3 and cathepsin L : expression, interactions, and contribution to pathophysiology in obesity and methamphetamine addictionFang-Min Wang · 2023 · theses.fr (ABES)
- Dissecting the role of long non-coding RNA in multiple myelomaSimone Zocchi · 2024 · theses.fr (ABES)
- Attempts to Achieve Targeted Covalent Inhibition of Hsp90 βTerin D’Amico, Tyelor S. Reynolds, Michael A. Serwetnyk, Brian S. J. Blagg · 2026 · Chemical Biology & Drug Design
- Eupalinolide B Ameliorates Diabetic Kidney Disease via Inhibition of Cell Division Cycle 37–Mediated Inflammatory PathwaysHuiying Li, Guanjun Li, Ling Huang, Tianyun Fan, Ying Zhang, Junzhe Zhang, Liwei Gu, Jianyou Wang, Li Hu, Hui Tang et al. · 2026 · Journal of the American Society of Nephrology
- Distinct cellular and subcellular distributions of the alpha and beta isoforms of Heat Shock Protein 90 in the mouse cerebral cortexHiroki Umeshima, Teruyoshi Hirayama, Ryosuke Adachi, Koichi Tomita · 2026 · Gene Expression Patterns
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- Microcolin A, a lipopeptide from marine cyanobacteria, suppresses the non-small cell lung carcinoma by regulating the C-terminal of Hsp90α and ROS/ERK signaling pathwaysZhanying Lu, Jie Wang, Song Li, Wenli Jiang, Xinlu Zhang, Yaodong Ning, Yao Xu, 焦炳华, Bo Hu, Haobing Yu et al. · 2026 · Biochemical Pharmacology
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- BindingDB Entry 50009799: Development of Heat Shock Protein (Hsp90) Inhibitors To Combat Resistance to Tyrosine Kinase Inhibitors through Hsp90-Kinase Interactions.BindingDB · 2021 · UC San Diego
- BindingDB Entry 50013045: Design, synthesis and bioevaluation of inhibitors targeting HSP90-CDC37 protein-protein interaction based on a hydrophobic core.BindingDB · 2022 · UC San Diego
- BindingDB Entry 50000704: Design, synthesis and pharmacological evaluation of 4,5-diarylisoxazols bearing amino acid residues within the 3-amido motif as potent heat shock protein 90 (Hsp90) inhibitors.BindingDB · 2019 · UC San Diego
- BindingDB Entry 50006714: C-terminal modulators of heat shock protein of 90 kDa (HSP90): State of development and modes of action.BindingDB · 2021 · UC San Diego
- BindingDB Entry 50022317: Elucidation of novel TRAP1-Selective inhibitors that regulate mitochondrial processes.BindingDB · 2025 · UC San Diego
- BindingDB Entry 50018167: Recent advances toward the development of Hsp90 C-terminal inhibitors.BindingDB · 2024 · UC San Diego
- BindingDB Entry 50018217: Natural heat shock protein 90 inhibitors in cancer and inflammation.BindingDB · 2024 · UC San Diego
- BindingDB Entry 50016614: Structure-activity relationship for the folding intermediate-selective inhibition of DYRK1A.BindingDB · 2023 · UC San Diego
- BindingDB Entry 50022152: Heat Shock Protein 90 Interactome-Mediated Proteolysis Targeting Chimera (HIM-PROTAC) Degrading Glutathione Peroxidase 4 to Trigger Ferroptosis.BindingDB · 2025 · UC San Diego
- BindingDB Entry 50019179: Targeted Protein Degradation Induced by HEMTACs Based on HSP90.BindingDB · 2024 · UC San Diego
- BindingDB Entry 50015063: Thermodynamic Dissection of Potency and Selectivity of Cytosolic Hsp90 Inhibitors.BindingDB · 2023 · UC San Diego
- BindingDB Entry 50045693: Structural investigation of B-Raf paradox breaker and inducer inhibitors.BindingDB · 2016 · UC San Diego
- BindingDB Entry 50008550: Discovery and Optimization of Small Molecules Targeting the Protein-Protein Interaction of Heat Shock Protein 90 (Hsp90) and Cell Division Cycle 37 as Orally Active Inhibitors for the Treatment of Colorectal Cancer.BindingDB · 2021 · UC San Diego
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