Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma

Lian, Christine Guo, Xu, Yufei, Ceol, Craig, Wu, Feizhen, Larson, Allison, Dresser, Karen, Xu, Wenqi, Tan, Li +23 more·2012·Cell

DOI 10.1016/j.cell.2012.07.033

Cited by (811)

Items 301–400 of 811

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High levels of 5-hydroxymethylcytosine (5hmC) is an adverse predictor of biochemical recurrence after prostatectomy in ERG-negative prostate cancer
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Clarence Yapp, Ajit J. Nirmal, Felix Zhou, Alex Y. H. Wong, Juliann B. Tefft, Yi Daniel Lu, Zhiguo Shang, Zoltan Maliga, Paula D.L.M. Montero Llopis, Gëorge F. Murphy et al. · 2025 · Nature Methods
Methylated DNA/RNA in Body Fluids as Biomarkers for Lung Cancer
Yan Lu, Shulin SL Li, Shiguo Zhu, Yabin Gong, J. Shi, Ling Xu · 2017 · Biological Procedures Online
The potential of DNA modifications as biomarkers and therapeutic targets in oncology
Anna Malgorzata Jankowska, Carl L. Millward, Charles W. Caldwell · 2015 · Expert Review of Molecular Diagnostics
Cytosine modifications in neurodevelopment and diseases
Bing Yao, Peng Jin · 2013 · Cellular and Molecular Life Sciences
The Role of Ten-Eleven Translocation Proteins in Inflammation
Christian Gerecke, Caue Egea Rodrigues, Thomas Homann, Burkhard Kleuser · 2022 · Frontiers in Immunology
Diagnostic utility of PRAME, p53 and 5-hmC immunostaining for distinguishing melanomas from naevi, neurofibromas, scars and other histological mimics
Robert V. Rawson, Eva R. Shteinman, Sameera Ansar, Ismael A. Vergara, John F. Thompson, Georgina Venetia Long, Richard A. Scolyer, James S. Wilmott · 2022 · Pathology
Diagnostic utility of 5‐hydroxymethylcytosine immunohistochemistry in melanocytic proliferations
Nemanja Rodić, John G. Zampella, Reema Sharma, Kathleen H. Burns, Janis Marie Taube · 2015 · Journal of Cutaneous Pathology
DNA Methylation Characteristics of Primary Melanomas with Distinct Biological Behaviour
Szilvia Ecsedi, Héctor Hernández‐Vargas, Sheila Coelho Soares‐Lima, Laura Vízkeleti, Réka Tóth, Viktória Lázár, Viktória Koroknai, Tímea Kiss, Gabriella Emri, Zdenko Herceg et al. · 2014 · PLoS ONE
Cytosine 5-Hydroxymethylation of the LZTS1 Gene Is Reduced in Breast Cancer
Matthias Wielscher, Willy Liou, Walter Pulverer, Christian Fridolin Singer, Christine Rappaport, Daniela Kandioler, Gerda Egger, Andreas Weinhäusel · 2013 · Translational Oncology
Decrease of 5hmC in gastric cancers is associated withTET1silencing due to with DNA methylation and bivalent histone marks atTET1CpG island 3′-shore
Jong‐Lyul Park, Hee-Jin Kim, Eun-Hye Seo, Oh-Hyung Kwon, Seon‐Young Kim, Seon‐Young Kim, Seon‐Young Kim, Kyu‐Sang Song, Gyeong Hoon Kang, Hyun Ja Kim et al. · 2015 · Oncotarget
Silencing HIF-1α induces TET2 expression and augments ascorbic acid induced 5-hydroxymethylation of DNA in human metastatic melanoma cells
Adam P. Fischer, Sarah L. Miles · 2017 · Biochemical and Biophysical Research Communications
The regulation of skeletal muscle fiber-type composition by betaine is associated with NFATc1/MyoD
Jingjing Du, Linyuan Shen, Peiwen Zhang, Zhendong Tan, Cheng Xiao, Jia Luo, Xue Zhao, Qiong Yang, Hao Gu, Anan Jiang et al. · 2018 · Journal of Molecular Medicine
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Yasuhiro Kyono, Samhitha Raj, Christopher J. Sifuentes, Nicolas Buisine, Laurent M. Sachs, Robert J. Denver · 2020 · Developmental Biology
Flanking sequences influence the activity of TET1 and TET2 methylcytosine dioxygenases and affect genomic 5hmC patterns
Sabrina Adam, Julia Bräcker, Viviane Klingel, Bernd Osteresch, Nicole Erika Radde, Jens Brockmeyer, Pavel Bashtrykov, Albert Jeltsch · 2022 · Communications Biology
Psoriatic Resolved Skin Epidermal Keratinocytes Retain Disease-Residual Transcriptomic and Epigenomic Profiles
Ameneh Ghaffarinia, Ferhan Ayaydin, Szilárd Póliska, Máté Manczinger, Beáta Szilvia Bolla, Lili Borbála Flink, Fanni Balogh, Zoltán Veréb, Renáta Bozó, Kornélia Szabó et al. · 2023 · International Journal of Molecular Sciences
Oct4 and the small molecule inhibitor, SC1, regulates Tet2 expression in mouse embryonic stem cells
Yongyan Wu, Zekun Guo, Ye Liu, Bo Tang, Yi Wang, Liping Yang, Juan Du, Yong Zhang · 2012 · Molecular Biology Reports
Induction of chronic oxidative stress, chronic inflammation and aberrant patterns of DNA methylation in the liver of titanium-exposed CBA/CaJ mice
Witawat Jangiam, Montree Tungjai, Kanokporn Noy Rithidech · 2015 · International Journal of Radiation Biology
Loss of 5hmC identifies a new type of aberrant DNA hypermethylation in glioma
Agustín F. Fernández, Gustavo F. Bayón, Marta Sierra, Rocío G. Urdinguio, Estela G. Toraño, Maria G García, Antonella Carella, Virginia López, Pablo Santamarina‐Ojeda, Raúl F. Pérez et al. · 2018 · Human Molecular Genetics
5-Hydroxymethylcytosine Expression in Proliferative Nodules Arising within Congenital Nevi Allows Differentiation from Malignant Melanoma
Olesya Pavlova, Sylvie Fraitag, Daniel Hohl · 2016 · Journal of Investigative Dermatology
TET2-Dependent Hydroxymethylome Plasticity Reduces Melanoma Initiation and Progression
Elise Bonvin, Enrico Radaelli, Martin Bizet, Flavie Luciani, Emilie Calonne, Pascale Putmans, David Nittner, Nitesh Kumar Singh, Sara Francesca Santagostino, Valérie Petit et al. · 2018 · Cancer Research
Overcoming BET Inhibitor Resistance in Malignant Peripheral Nerve Sheath Tumors
Jonathan M. Cooper, Amish J. Patel, Zhiguo Chen, Chung-Ping Liao, Kun Chen, Juan Mo, Yong Wang, Lu Q. Le · 2019 · Clinical Cancer Research
Epitranscriptomic systems regulate the translation of reactive oxygen species detoxifying and disease linked selenoproteins
Andrea Leonardi, Sara Evke, May Lee, Juan Andres Melendez, Thomas J. Begley · 2019 · Free Radical Biology and Medicine
Rapid and Label‐Free Detection of 5‐Hydroxymethylcytosine in Genomic DNA Using an Au/ZnO Nanorods Hybrid Nanostructure‐Based Electrochemical Sensor
Kiesar Sideeq Bhat, Hyejin Kim, Asrar Alam, Myunggon Ko, Jungeun An, Sooman Lim · 2021 · Advanced Healthcare Materials
Diverse antitumor effects of ascorbic acid on cancer cells and the tumor microenvironment
Takeru Maekawa, Toru Miyake, Masaji Tani, Shinji Üemoto · 2022 · Frontiers in Oncology
Decreased expression of ten-eleven translocation 1 protein is associated with some clinicopathological features in gastric cancer
Bartosz Adam Frycz, Dawid Murawa, Maciej Borejsza‐Wysocki, Ryszard Marciniak, P. Murawa, Michał Drews, Anna S Kolodziejczak, Katarzyna Tomela, Paweł Piotr Jagodziński · 2014 · Biomedicine & Pharmacotherapy
The potential role of O-GlcNAc modification in cancer epigenetics
Ewa Forma, Paweł Jóźwiak, Magdalena Bryś, Anna Krześlak · 2014 · Cellular & Molecular Biology Letters
5-Hydroxymethylcytosine expression is associated with poor survival in cervical squamous cell carcinoma
Liying Zhang, Changsong Han, Peiling Li, Xinchen Zhang · 2016 · Japanese Journal of Clinical Oncology
Initiation of inflammatory tumorigenesis by CTLA4 insufficiency due to type 2 cytokines
Jason M. Miska, Jen Bon Lui, Kevin H. Toomer, Priyadharshini Devarajan, Xiaodong Cai, JeanMarie Houghton, Diana M. Lopez, Maria Teresa Abreu, Gaofeng Wang, Zhibin Chen · 2018 · The Journal of Experimental Medicine
Age-Dependent Decrease of DNA Hydroxymethylation in Human T Cells
Thiên Phú Trương, Mamiko Sakata‐Yanagimoto, Momoko Yamada, Genta Nagae, Terukazu Enami, Rie Nakamoto-Matsubara, Hiroyuki Aburatani, Shigeru Chiba · 2015 · Journal of the Japan Society of the Reticuloendothelial System
5-Hydroxymethylcytosine discriminates between parathyroid adenoma and carcinoma
Elham Barazeghi, Anthony James Gill, Stan B. Sidhu, Olov Norlén, Roberto E. Dina, Fausto F Palazzo, Per Hellman, Peter L. H. Stalberg, Gunnar Westin · 2016 · Clinical Epigenetics
Dynamic interplay between locus-specific DNA methylation and hydroxymethylation regulates distinct biological pathways in prostate carcinogenesis
Shivani N. Kamdar, Linh Ho, Ken J. Kron, Ruth Isserlin, Theodorus van der Kwast, Alexandre R. Zlotta, Neil Eric Fleshner, Gary D. Bader, Bharati V. Bapat · 2016 · Clinical Epigenetics
Alterations of regulatory factors and DNA methylation pattern in thyroid cancer
Iulia Virginia Iancu, Anca Botezatu, Adriana Plesa, Irina Huică, Alina Fudulu, Adrian Albulescu, Marinela Bostan, Mirela Antonela Mihaila, Camelia Grancea, Dana Alice Manda et al. · 2020 · Cancer Biomarkers
Fatty Acid Synthase and Acetyl-CoA Carboxylase Are Expressed in Nodal Metastatic Melanoma But Not in Benign Intracapsular Nodal Nevi
Jad Saab, Maria Laureana Santos‐Zabala, Massimo F. Loda, Edward C. Stack, Travis J. Hollmann · 2017 · American Journal of Dermatopathology
3,6-Dihydroxyflavone regulates microRNA-34a through DNA methylation
Xiaoli Peng, Hui Chang, Junli Chen, Qianyong Zhang, Xiaoping Yu, Mantian Mi · 2017 · BMC Cancer
Genetic Characterization of Ten-Eleven-Translocation Methylcytosine Dioxygenase Alterations in Human Glioma
Theo F. J. Kraus, Andrea Greiner, Martina Steinmaurer, Vanessa Dietinger, Virginie Guibourt, Hans A. Kretzschmar · 2015 · Journal of Cancer
Hypersensitive quantification of global 5-hydroxymethylcytosine by chemoenzymatic tagging
Tamar Shahal, Omri Koren, Gabi Shefer, Naftali Stern, Yuval Ebenstein · 2018 · Analytica Chimica Acta
Effects of airborne particulate matter (PM10) from dust storm and thermal inversion on global DNA methylation in human peripheral blood mononuclear cells (PBMCs) in vitro
Maryam Faraji, Zahra Pourpak, Kazem Naddafi, Ramin Nabizadeh, Mohammad Hossein Nicknam, Mansour Shamsipour, Soheila Rezaei, Mohammad Ghanbari Ghozikali, Maryam Ghanbarian, Alireza Mesdaghinia · 2018 · Atmospheric Environment
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Feng Li, Christine Wan-Yin Yuan, Shuyun Xu, Tingjian Zu, Yvon Woappi, Catherine A. A. Lee, Phammela Abarzua, Michael Wells, Matthew R. Ramsey, Natasha Y. Frank et al. · 2019 · Journal of Investigative Dermatology
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Chris M. Li, Zhibin Chen · 2021 · Frontiers in Cell and Developmental Biology
Loss of 5-hydroxymethylcytosine induces chemotherapy resistance in hepatocellular carcinoma via the 5-hmC/PCAF/AKT axis
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Xuejiao Shi, Yue Yu, Mei Luo, Zhirong Zhang, Susheng Shi, Xiaoli Feng, Zhaoli Chen, Jie He · 2016 · PLoS ONE
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TET1 upregulation drives cancer cell growth through aberrant enhancer hydroxymethylation of HMGA2 in hepatocellular carcinoma
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Irina Pereira, Carina Monteiro, Miguel Pereira‐Silva, Diana Peixoto, Cláudia Nunes, Salette Reis, Francisco Veiga, Michael Richard Hamblin, Ana Cláudia Paiva‐Santos · 2023 · European Journal of Pharmaceutics and Biopharmaceutics
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Hao Huang, Xi Jiang, Jinhua Wang, Yuan-Yuan Li, Chun-Xiao Song, Ping Chen, Shenglai Li, S. Gurbuxani, S. Arnovitz, Yun-Gui Wang et al. · 2016 · Cancer Letters
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Loss of 5-Hydroxymethylcytosine Is an Epigenetic Biomarker in Cutaneous T-Cell Lymphoma
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Yuling Zhang, Yan Li, Yingying Wei, Huiping Sun, Huan Wang · 2017 · Talanta
Epigenetic Regulators of DNA Cytosine Modification: Promising Targets for Cancer Therapy
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