Mapping the Hallmarks of Lung Adenocarcinoma with Massively Parallel Sequencing

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E-Cadherin Loss Accelerates Tumor Progression and Metastasis in a Mouse Model of Lung Adenocarcinoma

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Testing EGFR with Idylla on Cytological Specimens of Lung Cancer: A Review

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Integrated Analysis of Genomic and Immunological Features in Lung Adenocarcinoma With Micropapillary Component

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CNOT3 targets negative cell cycle regulators in non-small cell lung cancer development

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FUT4 is involved in PD-1-related immunosuppression and leads to worse survival in patients with operable lung adenocarcinoma

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Brahma‐Related Gene‐1 (BRG1) promotes the malignant phenotype of glioblastoma cells

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Understanding the significance of biological clock and its impact on cancer incidence

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Thoracic SMARCA4-deficient undifferentiated tumor: A clinicopathological and prognostic analysis of 35 cases and immunotherapy efficacy

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Human ortholog of Drosophila Melted impedes SMAD2 release from TGF-β receptor I to inhibit TGF-β signaling

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Novel EPHB4 Receptor Tyrosine Kinase Mutations and Kinomic Pathway Analysis in Lung Cancer

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LUADpp: an effective prediction model on prognosis of lung adenocarcinomas based on somatic mutational features

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LncRNA, PLXDC2-OT Promoted the Osteogenesis Potentials of MSCs by Inhibiting the Deacetylation Function of RBM6/SIRT7 Complex and OSX Specific Isoform

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Primary cilia and cancer: a tale of many faces

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Integrating genetic mutations and expression profiles for survival prediction of lung adenocarcinoma

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Engineering Multidimensional Evolutionary Forces to Combat Cancer

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Targeting the Bromodomain of BRG-1/BRM Subunit of the SWI/SNF Complex Increases the Anticancer Activity of Temozolomide in Glioblastoma

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Synonymous Variants: Necessary Nuance in Our Understanding of Cancer Drivers and Treatment Outcomes

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Distinct mutational features across preinvasive and invasive subtypes identified through comprehensive profiling of surgically resected lung adenocarcinoma

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Deletion ofPtprdandCdkn2acooperate to accelerate tumorigenesis

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Limited evidence that cancer susceptibility regions are preferential targets for somatic mutation

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S1‐1/RBM10: Multiplicity and cooperativity of nuclear localisation domains

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Lung Cancer Mutations and Use of Targeted Agents in Hispanics

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LAPTM4B is associated with poor prognosis in NSCLC and promotes the NRF2-mediated stress response pathway in lung cancer cells

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KLF15 suppresses cell growth and predicts prognosis in lung adenocarcinoma

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Effect of Coexisting KRAS and TP53 Mutations in Patients Treated With Chemotherapy for Non–small-cell Lung Cancer

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The candidate oncogene (MCRS1) promotes the growth of human lung cancer cells via the miR–155–Rb1 pathway

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Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins

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Preoperative clinical and tumor genomic features associated with pathologic lymph node metastasis in clinical stage I and II lung adenocarcinoma

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Mutations and clinical significance of calcium voltage-gated channel subunit alpha 1E (CACNA1E) in non-small cell lung cancer

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Whole-exome sequencing to identify novel somatic mutations in squamous cell lung cancers

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Contrasting responses of non‐small cell lung cancer to antiangiogenic therapies depend on histological subtype

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The enigmatic oncogene and tumor suppressor‐like properties of RAD54B: Insights into genome instability and cancer

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Distribution of circulating tumor DNA in lung cancer: analysis of the primary lung and bone marrow along with the pulmonary venous and peripheral blood

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Integrated analysis of dosage effect lncRNAs in lung adenocarcinoma based on comprehensive network

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Diagnostic and Predictive Immunohistochemistry for Non–Small Cell Lung Carcinomas

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DNA mismatch repair in the context of chromatin

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CCL25 promotes the migration and invasion of non‑small cell lung cancer cells by regulating VEGF and MMPs in a CCR9‑dependent manner

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Targeting PGM3 as a Novel Therapeutic Strategy in KRAS/LKB1 Co-Mutant Lung Cancer

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A triple exon-skipping luciferase reporter assay identifies a new CLK inhibitor pharmacophore

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Mechanism of error-free replication across benzo[a]pyrene stereoisomers by Rev1 DNA polymerase

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Novel genetic variants in HDAC2 and PPARGC1A of the CREB‐binding protein pathway predict survival of non‐small‐cell lung cancer

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Supervised mutational signatures for obesity and other tissue-specific etiological factors in cancer

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Early-Stage Lung Adenocarcinoma MDM2 Genomic Amplification Predicts Clinical Outcome and Response to Targeted Therapy

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DNA Methylation Malleability and Dysregulation in Cancer Progression: Understanding the Role of PARP1

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Paradoxical Behavior of Oncogenes Undermines the Somatic Mutation Theory

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Comprehensive landscape of the ST3GAL family reveals the significance of ST3GAL6-AS1/ST3GAL6 axis on EGFR signaling in lung adenocarcinoma cell invasion

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The Impact of ETV6-NTRK3 Oncogenic Gene Fusions on Molecular and Signaling Pathway Alterations

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Mutations in the Serine/Threonine Kinase BRAF: Oncogenic Drivers in Solid Tumors

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RAD51 variant proteins from human lung and kidney tumors exhibit DNA strand exchange defects

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Non-invasive urine testing of EGFR activating mutation and T790M resistance mutation in non-small cell lung cancer

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A quantitative method for assessing smoke associated molecular damage in lung cancers

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Blood‐based circulating tumor DNA mutations as a diagnostic and prognostic biomarker for lung cancer

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Long non-coding RNA LINC01116 is activated by EGR1 and facilitates lung adenocarcinoma oncogenicity via targeting miR-744-5p/CDCA4 axis

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HaloPlex Targeted Resequencing for Mutation Detection in Clinical Formalin-Fixed, Paraffin-Embedded Tumor Samples

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Nuclear Magnetic Resonance Structure of a Novel Globular Domain in RBM10 Containing OCRE, the Octamer Repeat Sequence Motif

Martin, B. T., Serrano, P., Geralt, M., & Wüthrich, K. (2015) · Structure · doi:10.1016/j.str.2015.10.029 · Cited by 20

The genomic landscape of lung cancer in never-smokers from the Women’s Health Initiative

Moorthi, S., Paguirigan, A. L., Itagi, P., Ko, M., Pettinger, M. B., Hoge, A. C. H., Nag, A., Patel, N. A., Wu, F., Sather, C. L., et al. (2024) · JCI Insight · doi:10.1172/jci.insight.174643 · Cited by 21

Genetic Clonality as the Hallmark Driving Evolution of Non-Small Cell Lung Cancer

Nicoś, M., & Krawczyk, P. A. (2022) · Cancers · doi:10.3390/cancers14071813 · Cited by 21

Pyrazine Moiety: Recent Developments in Cancer Treatment

Sahu, R., Shah, K., Gautam, Y., & Sahu, K. (2023) · Current Organic Chemistry · doi:10.2174/1385272827666230816105317 · Cited by 19

Discovery of SMD-3236: A Potent, Highly Selective and Efficacious SMARCA2 Degrader for the Treatment of SMARC4-Deficient Human Cancers

Yang, L., Tu, W., Leng, L., Huang, L., Jiang, W., Wang, M., Wang, Y., Meagher, J. L., Chinnaswamy, K., Stuckey, J. A., et al. (2025) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.4c01904 · Cited by 19

Differential downregulation of Rbm5 and Rbm10 during skeletal and cardiac differentiation

Loiselle, J. J., & Sutherland, L. C. (2013) · In Vitro Cellular & Developmental Biology - Animal · doi:10.1007/s11626-013-9708-z · Cited by 19

From mice to men: GEMMs as trial patients for new NSCLC therapies

Hayes, S. A., Hudson, A. L., Clarke, S. J., Molloy, M. P., & Howell, V. M. (2014) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2014.04.002 · Cited by 19

Genomic aberrations guiding treatment of non-small cell lung cancer patients

Saber, A., van der Wekken, A. J., Hiltermann, T. J. N., Kok, K., van den Berg, A., & Groen, H. J. M. (2015) · Cancer Treatment Communications · doi:10.1016/j.ctrc.2015.03.005 · Cited by 19

Molecular Pathology of Lung Cancer: Current Status and Future Directions

Roh, M. S. (2014) · Tuberculosis & respiratory diseases · doi:10.4046/trd.2014.77.2.49 · Cited by 20

SF3A1 and pancreatic cancer: new evidence for the association of the spliceosome and cancer

Tian, J., Liu, Y., Zhu, B., Tian, Y., Zhong, R., Chen, W., Lu, X., Zou, L., Shen, N., Qian, J., et al. (2015) · Oncotarget · doi:10.18632/oncotarget.5647 · Cited by 19

Identification of lung cancer histology-specific variants applying Bayesian framework variant prioritization approaches within the TRICL and ILCCO consortia

Brenner, D. R., Amos, C. I., Brhane, Y., Timofeeva, M. N., Caporaso, N. E., Wang, Y., Christiani, D. C., Bickeböller, H., Yang, P., Albanes, D., et al. (2015) · Carcinogenesis · doi:10.1093/carcin/bgv128 · Cited by 20

Inhibition of fibroblast growth factor receptor 3-dependent lung adenocarcinoma with a human monoclonal antibody

Yin, Y., Ren, X., Smith, C. S., Guo, Q., Malabunga, M., Guernah, I., Zhang, Y., Shen, J., Sun, H. D., Chehab, N. H., et al. (2016) · Disease Models & Mechanisms · doi:10.1242/dmm.024760 · Cited by 21

Development of a robust DNA quality and quantity assessment qPCR assay for targeted next-generation sequencing library preparation

Dang, J., Méndez, P., Lee, S. C. L., Kim, J. W., Yoon, J., Kim, T. W., Sailey, C., Jablons, D. M., & Kim, I.-J. (2016) · International Journal of Oncology · doi:10.3892/ijo.2016.3654 · Cited by 19

Co-dependency of PKCδ and K-Ras: inverse association with cytotoxic drug sensitivity in KRAS mutant lung cancer

Ohm, A. M., Tan, A. C., Heasley, L. E., & Reyland, M. E. (2017) · Oncogene · doi:10.1038/onc.2017.27 · Cited by 19

Established, emerging and elusive molecular targets in the treatment of lung cancer

Gallant, J., & Lovly, C. M. (2018) · The Journal of Pathology · doi:10.1002/path.5038 · Cited by 22

Spindle Epithelial Tumor with Thymus-Like Differentiation (SETTLE): A Next-Generation Sequencing Study

Stevens, T. M., Morlote, D. M., Swensen, J. J., Ellis, M., Harada, S., Spencer, S. A., Granada, C. N. P., Folpe, A. L., & Gatalica, Z. (2018) · Head and Neck Pathology · doi:10.1007/s12105-018-0927-1 · Cited by 19

Human transcription factor and protein kinase gene fusions in human cancer

Salokas, K., Weldatsadik, R. G., & Varjosalo, M. T. (2020) · Scientific Reports · doi:10.1038/s41598-020-71040-8 · Cited by 19

Mechanisms of autoregulation of C3G, activator of the GTPase Rap1, and its catalytic deregulation in lymphomas

Carabias, A., Gómez-Hernández, M., de Cima, S., Rodríguez-Blázquez, A., Morán-Vaquero, A., González-Sáenz, P., Guerrero, C., & de Pereda, J. M. (2020) · Science Signaling · doi:10.1126/scisignal.abb7075 · Cited by 19

Mutational landscape of primary pulmonary salivary gland-type tumors through targeted next-generation sequencing

Wang, F., Xi, S., Hao, W., Yang, X., Deng, L., Xu, Y., Wu, X., Zeng, L., Guo, K., & Wang, H. (2021) · Lung Cancer · doi:10.1016/j.lungcan.2021.07.011 · Cited by 19

Multiple roles of extracellular fibroblast growth factors in lung cancer cells

Suzuki, T., Yasuda, H., FUNAISHI, K., Arai, D., Ishioka, K., Ohgino, K., Tani, T., Hamamoto, J., Ohashi, A., Naoki, K., et al. (2014) · International Journal of Oncology · doi:10.3892/ijo.2014.2718 · Cited by 19

Abstract 1112: Whole exome and whole genome sequence analysis of lung adenocarcinoma.

Chmielecki, J., Rosenberg, M. W., Imielinski, M. B., Hernandez, B., Lawrence, M. S., Sivachenko, A., Cibulskis, K., Voet, D., Sougnez, C. L., Gabriel, S., et al. (2013) · Cancer Research · doi:10.1158/1538-7445.am2013-1112

Somatic mutations affect key pathways in lung adenocarcinoma

Ding, L., Getz, G., Wheeler, D. A., Mardis, E. R., McLellan, M. D., Cibulskis, K., Sougnez, C., Greulich, H., Muzny, D. M., Morgan, M. B., et al. (2008) · Nature · doi:10.1038/nature07423 · Cited by 2,681

Abstract 1113: The comprehensive mutational profiling of lung adenocarcinoma through large-scale RNA sequencing analysis.

Lee, W., Ju, Y. S., Shin, J.-Y., Lee, J. J.-K., Bleazard, T., Lee, J.-H., Kim, J.-O., Yu, S.-B., Kim, J., Rhee, H., et al. (2013) · Cancer Research · doi:10.1158/1538-7445.am2013-1113

Abstract 1682: Uncovering signals of somatic selection through whole exome and whole genome sequencing of lung adenocarcinoma

Imielinski, M. B., Hernandez, B., Lawrence, M. S., Hodis, E., Kryukov, G., Stojanov, P., Sivachenko, A., Cibulskis, K., Sougnez, C. L., Auclair, D., et al. (2012) · Cancer Research · doi:10.1158/1538-7445.am2012-1682

The transcriptional landscape and mutational profile of lung adenocarcinomaPreprint

Seo, J., Ju, Y. S., Lee, W., Shin, J.-Y., Lee, J. J.-K., Bleazard, T., Lee, J., Jung, Y. J., Kim, J. O., Shin, J.-Y., et al. (2012) · Genome Research · doi:10.1101/gr.145144.112 · Cited by 603