Mapping the Hallmarks of Lung Adenocarcinoma with Massively Parallel Sequencing

Imielinski, Marcin, Berger, Alice H., Hammerman, Peter S., Hernandez, Bryan, Pugh, Trevor J., Hodis, Eran, Cho, Jeonghee, Suh, James +37 more·2012·Cell

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Items 301–400 of 1,000

  1. Tobacco smoking and cessation and PD-L1 inhibitors in non-small cell lung cancer (NSCLC): a review of the literature
    Jan Norum, Carsten Nieder · 2018 · ESMO Open
  2. An LKB1–SIK Axis Suppresses Lung Tumor Growth and Controls Differentiation
    Murray, Christopher W., Brady, Jennifer J., Tsai, Min K., Li, Chuan, Winters, Ian P., Tang, Rui, Andrejka, Laura, Ma, Rosanna K., Kunder, Christian A., Chu, Pauline et al. · 2019 · Cancer Discovery
  3. Understanding mutagenesis through delineation of mutational signatures in human cancer
    Petljak, Mia, Alexandrov, Ludmil B. · 2016 · Carcinogenesis
  4. Aberrant transcriptional regulations in cancers: genome, transcriptome and epigenome analysis of lung adenocarcinoma cell lines
    Ayako Suzuki, Hideki Makinoshima, Hiroyuki Wakaguri, Hiroyasu Esumi, Sumio Sugano, Takashi Kohno, Katsuya Tsuchihara, Yutaka Suzuki · 2014 · Nucleic Acids Research
  5. Comprehensive Characterization of Oncogenic Drivers in Asian Lung Adenocarcinoma
    Shiyong Li, Yoon‐La Choi, Zhuolin Gong, Xiao Liu, Maruja E. Lira, Zhengyan Kan, Ensel Oh, Jian Wang, Jason C. Ting, X.S. Ye et al. · 2016 · Journal of Thoracic Oncology
  6. Role of CPS1 in Cell Growth, Metabolism, and Prognosis in LKB1-Inactivated Lung Adenocarcinoma
    Müge Çeliktaş, Ichidai Tanaka, S. C. Tripathi, Johannes Francois Fahrmann, Clemente Aguilar-Bonavides, Pamela Andrea Villalobos, Oliver Delgado, Dilsher S. Dhillon, Jennifer B. Dennison, Edwin Justin Ostrin et al. · 2016 · JNCI Journal of the National Cancer Institute
  7. Whole-genome sequencing revealed novel prognostic biomarkers and promising targets for therapy of ovarian clear cell carcinoma
    Hiroaki Itamochi, Tetsuro Oishi, Nao Oumi, Satoshi Takeuchi, Kosuke Yoshihara, Mikio Mikami, Nobuo Yaegashi, Yasuhisa Terao, Kazuhiro Takehara, Kimio Ushijima et al. · 2017 · British Journal of Cancer
  8. CDKN2A/p16 Inactivation Mechanisms and Their Relationship to Smoke Exposure and Molecular Features in Non–Small-Cell Lung Cancer
    Tam, Kit W., Zhang, Wei, Soh, Junichi, Stastny, Victor, Chen, Min, Sun, Han, Thu, Kelsie, Rios, Jonathan J., Yang, Chenchen, Marconett, Crystal N. et al. · 2013 · Journal of Thoracic Oncology
  9. Frequent alterations in cytoskeleton remodelling genes in primary and metastatic lung adenocarcinomas
    Kui Wu, Xin Zhang, Fuqiang Li, Dakai Xiao, Yong Hou, Shida Zhu, Dongbing Liu, Xiaofei Ye, Mingzhi Ye, Jie Yang et al. · 2015 · Nature Communications
  10. Genetic Diversity of Pancreatic Ductal Adenocarcinoma and Opportunities for Precision Medicine
    Erik S. Knudsen, Eileen Mary O'Reilly, Jonathan Robert Brody, Agnieszka Katarzyna Witkiewicz · 2015 · Gastroenterology
  11. Salt-inducible kinases regulate growth through the Hippo signalling pathway in Drosophila
    Michael C. Wehr, Maxine V. Holder, Ieva Gailite, Rebecca E. Saunders, Tobias M Maile, Elena Ciirdaeva, Rachael Instrell, Ming Jiang, Michael T. Howell, Moritz J. Rossner et al. · 2012 · Nature Cell Biology
  12. A two-circular RNA signature as a noninvasive diagnostic biomarker for lung adenocarcinoma
    Xiaoxia Liu, Yie Yang, Xiao Liu, Mengyu Zhang, Rui Li, Yunhong Yin, Yi-Qing Qu · 2019 · Journal of Translational Medicine
  13. Mutation signatures of carcinogen exposure: genome-wide detection and new opportunities for cancer prevention
    Song Ling Poon, John Richard McPherson, Patrick B. O. Tan, Bin Tean Teh, Steve Rozen · 2014 · Genome Medicine
  14. Mapping the molecular determinants of BRAF oncogene dependence in human lung cancer
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  15. Exosomal lipids for classifying early and late stage non-small cell lung cancer
    Teresa W.‐M. Fan, Xiaofei Zhang, Chi Wang, Ye Yang, Woo-Young Kang, Susanne M. Arnold, Richard M. Higashi, Jinze Liu, Andrew N. Lane · 2018 · Analytica Chimica Acta
  16. Comparative Molecular Life History of Spontaneous Canine and Human Gliomas
    Samirkumar B. Amin, Kevin J. Anderson, C. Elizabeth Boudreau, Emmanuel Martínez-Ledesma, Emre Kocakavuk, Kevin C. Johnson, Floris P Barthel, Frederick S. Varn, Cynthia Kassab, Xiaoyang Ling et al. · 2020 · Cancer Cell
  17. CDKN2A loss-of-function predicts immunotherapy resistance in non-small cell lung cancer
    Stanley I. Gutiontov, William Tyler Turchan, Liam Flinn Spurr, Sherin Juliet Rouhani, Carolina Soto Chervin, George Steinhardt, Angela M. Lager, Pankhuri Wanjari, Renuka Malik, Philip P. Connell et al. · 2021 · Scientific Reports
  18. NetSig: network-based discovery from cancer genomes
    Horn, Heiko, Lawrence, Michael S, Chouinard, Candace R, Shrestha, Yashaswi, Hu, Jessica Xin, Worstell, Elizabeth, Shea, Emily, Ilic, Nina, Kim, Eejung, Kamburov, Atanas et al. · 2018 · Nature Methods
  19. Molecular Characterization of Acquired Resistance to the BRAF Inhibitor Dabrafenib in a Patient with BRAF-Mutant Non–Small-Cell Lung Cancer
    Charles M. Rudin, Kelvin K. Hong, Michael R. W. Streit · 2013 · Journal of Thoracic Oncology
  20. An epigenetic gateway to brain tumor cell identity
    Stephen C. Mack, Christopher G. Hubert, Tyler E. Miller, Michael D. Taylor, Jeremy N. Rich · 2015 · Nature Neuroscience
  21. Characterization of Somatic Mutations in Air Pollution-Related Lung Cancer
    Xianjun Yu, Minjun Yang, Bo Zhou, Guizhen Wang, Yunchao Huang, Lichuan Wu, Xin Cheng, Zhesheng Wen, Jin-Yan Huang, Yundong Zhang et al. · 2015 · EBioMedicine
  22. Unraveling the clonal hierarchy of somatic genomic aberrations
    Davide Prandi, Sylvan C. Baca, Alessandro Romanel, Christopher E. Barbieri, Juan‐Miguel Mosquera, Jacqueline Fontugne, Himisha Beltran, Andrea Sboner, Levi A. Garraway, Mark A. Rubin et al. · 2014 · Genome biology
  23. RICTOR Amplification Defines a Novel Subset of Patients with Lung Cancer Who May Benefit from Treatment with mTORC1/2 Inhibitors
    Haiying Cheng, Yiyu Zou, Jeffrey S. Ross, Kai Wang, Xuewen Liu, Balázs Halmos, Siraj Mahamed Ali, Huijie Liu, Amit Verma, Cristina Montagna et al. · 2015 · Cancer Discovery
  24. STAT3: Versatile Functions in Non-Small Cell Lung Cancer
    Julian Mohrherr, Iris Z. Uras, Herwig Peter Moll, Emilio Casanova · 2020 · Cancers
  25. miR-6077 promotes cisplatin/pemetrexed resistance in lung adenocarcinoma via CDKN1A/cell cycle arrest and KEAP1/ferroptosis pathways
    Guoshu Bi, Jiaqi Liang, Mengnan Zhao, Huan Zhang, Xing Yu Jin, Tao Lu, Yuansheng Zheng, Yunyi Bian, Zhencong Chen, Yiwei Huang et al. · 2022 · Molecular Therapy — Nucleic Acids
  26. The splicing factor U2AF1 contributes to cancer progression through a noncanonical role in translation regulation
    Murali Palangat, Dimitrios G. Anastasakis, Dennis Liang Fei, Katherine E. Lindblad, Robert K. Bradley, Christopher Simon Hourigan, Markus Hafner, Daniel R. Larson · 2019 · Genes & Development
  27. A Cancer Theory Kerfuffle Can Lead to New Lines of Research
    S. G. Baker · 2014 · JNCI Journal of the National Cancer Institute
  28. Lung Cancer Cell Line Screen Links Fanconi Anemia/BRCA Pathway Defects to Increased Relative Biological Effectiveness of Proton Radiation
    Qi Liu, Priyanjali Ghosh, Nicole Magpayo, M Testa, Shikui Tang, Liliana Gheorghiu, Peter J. Biggs, Harald Paganetti, Jason Alexander Efstathiou, Hsiao‐Ming Lu et al. · 2015 · International Journal of Radiation Oncology*Biology*Physics
  29. Rho GTPases: Anti- or pro-neoplastic targets?
    Inuk Zandvakili, Yiwei Lin, J C Morris, Yunfei Zheng · 2016 · Oncogene
  30. Toward A variable RBE for proton beam therapy
    Henning Willers, Antiño R. Allen, David R. Grosshans, Stephen Joseph McMahon, Cläre von Neubeck, Claudia Wiese, Bhadrasain Vikram · 2018 · Radiotherapy and Oncology
  31. Impact of Soy Isoflavones on the Epigenome in Cancer Prevention
    Maria Pudenz, Kevin Roth, Clarissa Gerhäuser · 2014 · Nutrients
  32. WWOX at the crossroads of cancer, metabolic syndrome related traits and CNS pathologies
    C. Marcelo Aldaz, Brent W. Ferguson, Martı́n C. Abba · 2014 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
  33. Primase-polymerases are a functionally diverse superfamily of replication and repair enzymes
    Thomas A. Guilliam, Benjamin A. Keen, Nigel C. Brissett, Aidan J. Doherty · 2015 · Nucleic Acids Research
  34. Understanding genomic alterations in cancer genomes using an integrative network approach
    Edwin Wang · 2012 · Cancer Letters
  35. EZH2 in Cancer Progression and Potential Application in Cancer Therapy: A Friend or Foe?
    Ke-Sin Yan, Chia‐Yuan Lin, Tan-Wei Liao, Cheng-Ming Peng, Shou-Chun Lee, Yi‐Jui Liu, Wing Pong Chan, Ruey‐Hwang Chou · 2017 · International Journal of Molecular Sciences
  36. Differential Functions of Splicing Factors in Mammary Transformation and Breast Cancer Metastasis
    Sung‐Hee Park, Mattia Brugiolo, Martin Akerman, Shipra Das, Laura M. Urbanski, Adam Geier, Anil K Kesarwani, Martin Y. Fan, Nathan K. Leclair, Kuan‐Ting Lin et al. · 2019 · Cell Reports
  37. Early Events in the Molecular Pathogenesis of Lung Cancer
    Humam N. Kadara, Paul A. Scheet, Ignacio Ivan Wistuba, Avrum E. Spira · 2016 · Cancer Prevention Research
  38. The Spectrum and Clinical Impact of Epigenetic Modifier Mutations in Myeloma
    Charlotte Pawlyn, Martin Kaiser, Christoph Johann Heuck, Lorenzo Melchor, Christopher P. Wardell, Alex Murison, Shweta S. Chavan, David C. Johnson, Dil B Begum, Nasrin M. Dahir et al. · 2016 · Clinical Cancer Research
  39. Non-V600 BRAF mutations recurrently found in lung cancer predict sensitivity to the combination of Trametinib and Dabrafenib
    Maxim Noeparast, Erik Teugels, Philippe Giron, Gil Verschelden, Sylvia De Brakeleer, Lore Decoster, Jacques De Grève · 2016 · Oncotarget
  40. Activating de novo mutations in NFE2L2 encoding NRF2 cause a multisystem disorder
    Peter Huppke, Susann Weißbach, Joseph A. Church, Rhonda E. Schnur, Martina Krusen, Steffi F. Dreha‐Kulaczewski, W. Nikolaus Kühn‐Velten, Annika Wolf, Brenda Huppke, Francisca Millan et al. · 2017 · Nature Communications
  41. APOBEC Mutagenesis and Copy Number Alterations are Drivers of Proteogenomic Tumor Evolution and Heterogeneity in Metastatic Thoracic Tumors
    Nitin Roper, Shaojian Gao, Tapan Kumar Maity, Abdul Rouf Banday, Xu Zhang, Abhilash Karavattu Venugopalan, Constance M. Cultraro, Rajesh Patidar, Sivasish Sindiri, Anna‐Leigh Brown et al. · 2018 · Cell Reports
  42. Long noncoding RNA LINC00673-v4 promotes aggressiveness of lung adenocarcinoma via activating WNT/β-catenin signaling
    Hongyu Guan, Ting Zhu, Shanshan Wu, Shihua Liu, Bangdong Liu, Jueheng Wu, Junchao Cai, Xun Zhu, Xin Zhang, Mu‐Sheng Zeng et al. · 2019 · Proceedings of the National Academy of Sciences
  43. APOBEC-Induced Cancer Mutations Are Uniquely Enriched in Early-Replicating, Gene-Dense, and Active Chromatin Regions
    Marat D. Kazanov, Steven A. Roberts, Paz P Polak, John A. Stamatoyannopoulos, Leszek J. Klimczak, Dmitry A. Gordenin, Shamil R. Sunyaev · 2015 · Cell Reports
  44. Identification of cancer-cytotoxic modulators of PDE3A by predictive chemogenomics
    de Waal, Luc, Lewis, Timothy A, Rees, Matthew G, Tsherniak, Aviad, Wu, Xiaoyun, Choi, Peter S, Gechijian, Lara, Hartigan, Christina, Faloon, Patrick W, Hickey, Mark J et al. · 2016 · Nature Chemical Biology
  45. MicroRNA-29c functions as a tumor suppressor by targeting VEGFA in lung adenocarcinoma
    Lipin Liu, Nan Bi, Lihong Wu, Xiao Ding, Yu Men, Wei Zhou, Lin Li, Weimin Zhang, Susheng Shi, Yongmei Song et al. · 2017 · Molecular Cancer
  46. Transcriptome-wide splicing network reveals specialized regulatory functions of the core spliceosome
    Malgorzata Ewa Rogalska, Estefanía Mancini, Sophie Bonnal, André Gohr, Bryan M. Dunyak, Niccolò Arecco, Peter G. Smith, Frédéric H. Vaillancourt, Juan Valcárcel · 2024 · Science
  47. Modelling mutational landscapes of human cancers in vitro
    Magali Olivier, Annette Weninger, Maude Ardin, Hana Hušková, Xavier Castells, Maxime Vallée, James McKay, Tatiana Nedelko, Karl–Rudolf Muehlbauer, Hiroyuki Marusawa et al. · 2014 · Scientific Reports
  48. Surgery for NSCLC in the era of personalized medicine
    Tetsuya Mitsudomi, Kenichi Suda, Yasushi Yatabe · 2013 · Nature Reviews Clinical Oncology
  49. Implementation of Amplicon Parallel Sequencing Leads to Improvement of Diagnosis and Therapy of Lung Cancer Patients
    Katharina König, Martin Peifer, Jana Fassunke, Michaela A. Ihle, Helen Künstlinger, Carina Heydt, Katrin Stamm, Frank Ueckeroth, Claudia Vollbrecht, Marc Christiaan Allardt Bos et al. · 2015 · Journal of Thoracic Oncology
  50. SMARCA4/BRG1–Deficient Non–Small Cell Lung Carcinomas: A Case Series and Review of the Literature
    Aruna Nambirajan, Varsha Singh, Nishu Bhardwaj, Saurabh Mittal, Sunil Kumar, Deepali Jain · 2020 · Archives of Pathology & Laboratory Medicine
  51. Cell-autonomous and non-cell-autonomous mechanisms of transformation by amplified FGFR1 in lung cancer.
    F. Malchers, F. Dietlein, Jakob Schöttle, Xin Lu, L. Nogova, K. Albus, L. Fernandez-Cuesta, J. Heuckmann, O. Gautschi, J. Diebold et al. · 2014 · Cancer Discovery
  52. Genetic Alterations of TRAF Proteins in Human Cancers
    Sining Zhu, Juan Jin, Samantha Gokhale, Angeli M. Lu, Haiyan Shan, Jian‐Jun Feng, Ping Xie · 2018 · Frontiers in Immunology
  53. Neurofibromin and suppression of tumorigenesis: beyond the GAP
    Juan Mo, Stefanie L. Moye, Renee M. McKay, L. Le · 2022 · Oncogene
  54. Mechanisms of genome instability induced by RNA-processing defects
    Yujia A. Chan, Philip Hieter, Peter C. Stirling · 2014 · Trends in Genetics
  55. Site-specific methylation of Notch1 controls the amplitude and duration of the Notch1 response
    Kerstin Hein, Gerhard Mittler, Wiebke Cizelsky, Michael Kühl, Francesca Ferrante, Robert Liefke, Ina M. Berger, Steffen Just, Eric Sträng, Hans Armin Kestler et al. · 2015 · Science Signaling
  56. KRAS and NKX2-1 Mutations in Invasive Mucinous Adenocarcinoma of the Lung
    David H. Hwang, Lynette Marie Sholl, Vanesa Rojas‐Rudilla, Dimity L. Hall, Priyanka Shivdasani, Elizabeth P. Garcia, Laura E. MacConaill, Marina Vivero, Jason L. Hornick, Frank C. Kuo et al. · 2016 · Journal of Thoracic Oncology
  57. Tumor B7-H3 (CD276) expression and smoking history in relation to lung adenocarcinoma prognosis
    Kentaro Inamura, Yusuke Yokouchi, Maki Kobayashi, Rie Sakakibara, Hironori Ninomiya, Sophia Subat, Hiroko Nagano, Kimie Nomura, Sakae Okumura, Tomoko Shibutani et al. · 2016 · Lung Cancer
  58. Wild-Type U2AF1 Antagonizes the Splicing Program Characteristic of U2AF1-Mutant Tumors and Is Required for Cell Survival
    Dennis Liang Fei, Hayley Motowski, Rakesh Chatrikhi, Sameer Prasad, Jovian Yu, Shaojian Gao, Clara L. Kielkopf, Robert K. Bradley, HAROLD E. VARMUS · 2016 · PLoS Genetics
  59. Hippo and TGF-β interplay in the lung field
    Akira Saito, Takeshi Nagase · 2015 · American Journal of Physiology-Lung Cellular and Molecular Physiology
  60. Comparison of Prevalence and Types of Mutations in Lung Cancers Among Black and White Populations
    Joshua David Campbell, Christopher S. Lathan, Lynette Marie Sholl, Matthew A. Ducar, Mikenah Vega, Ashwini Sunkavalli, Ling Lin, Megan Hanna, Laura Schubert, Aaron R. Thorner et al. · 2017 · JAMA Oncology
  61. In vivo CRISPR screening unveils histone demethylase UTX as an important epigenetic regulator in lung tumorigenesis
    Qibiao Wu, Yahui Tian, Jian Zhang, Xinyuan Tong, Hsin‐Yi Huang, Shuai Li, Hong Zhao, Ying Tang, Chongze Yuan, Kun Wang et al. · 2018 · Proceedings of the National Academy of Sciences
  62. Interpretable identification of cancer genes across biological networks via transformer-powered graph representation learning
    Xiaorui Su, Pengwei Hu, Dongxu Li, Bo-Wei Zhao, Zhaomeng Niu, Thomas Herget, Philip S. Yu, Lun Hu · 2025 · Nature Biomedical Engineering
  63. Molecular mechanisms and regulation of inflammasome activation and signaling: sensing of pathogens and damage molecular patterns
    Sagar R. Dubey, Cynthia Turnbull, Abhimanu Pandey, Anyang Zhao, Melan Kurera, Radhwan Nidal Al-Zidan, Cheng Xing Shen, Manjul Gautam, Shreya Mahajan, Poonam S. Jadhav et al. · 2025 · Cellular and Molecular Immunology
  64. Oncogenes in non-small-cell lung cancer: emerging connections and novel therapeutic dynamics
    Giulia Maria Stella, Maurizio Luisetti, Ernesto Pozzi, Paolo Maria Comoglio · 2013 · The Lancet Respiratory Medicine
  65. Laying a solid foundation for Manhattan – ‘setting the functional basis for the post-GWAS era’
    Xiaoyang Zhang, Swneke Donovan Bailey, Mathieu Lupien · 2014 · Trends in Genetics
  66. Effects of Charged Particles on Human Tumor Cells
    Kathryn D. Held, Hidemasa Kawamura, Takuya Kaminuma, Athena Paz, Yukari Yoshida, Qi Liu, Henning Willers, Akihisa Takahashi · 2016 · Frontiers in Oncology
  67. An integrative analysis of colon cancer identifies an essential function for PRPF6 in tumor growth
    Adam S. Adler, Mark L. McCleland, Sharon Fong Yee, Murat Yaylaoglu, Sofia Hussain, Ely Cosino, Gabriel Quiñones, Zora D. Modrusan, Somasekar Seshagiri, Eric Torres et al. · 2014 · Genes & Development
  68. SETting the Stage for Cancer Development: SETD2 and the Consequences of Lost Methylation
    Catherine C. Fahey, Ian J. Davis · 2017 · Cold Spring Harbor Perspectives in Medicine
  69. Gene mutations in primary tumors and corresponding patient-derived xenografts derived from non-small cell lung cancer
    Chuncheng Hao, Li Wang, Shaohua Peng, Mengru Cao, Hongyu Li, Jing Hu, Xiao Huang, Wei Liu, Hui Zhang, Shuhong Wu et al. · 2014 · Cancer Letters
  70. Functional analysis reveals that RBM10 mutations contribute to lung adenocarcinoma pathogenesis by deregulating splicing
    Jiawei Zhao, Yue Sun, Yin Huang, Fan Song, Zengshu Huang, Yufang Bao, Ji Zuo, David W. Saffen, Zhen Shao, Wen Liu et al. · 2017 · Scientific Reports
  71. Mutation profile of non-small cell lung cancer revealed by next generation sequencing
    Ya‐Sian Chang, Siang-Jyun Tu, Yu‐Chia Chen, Ting‐Yuan Liu, Ya-Ting Lee, Ju-Chen Yen, Hsin‐Yuan Fang, Jan‐Gowth Chang · 2021 · Respiratory Research
  72. The Changing Landscape of Hepatocellular Carcinoma
    Erik S. Knudsen, Purva Gopal, Amit G. Singal · 2014 · American Journal Of Pathology
  73. An Integrative Analysis of the Tumorigenic Role of TAZ in Human Non–Small Cell Lung Cancer
    Satoshi F. Noguchi, Akira Saito, Masafumi Horie, Yu Mikami, Hiroshi I. Suzuki, Yasuyuki Morishita, Mitsuhiro Ohshima, Yoshimitsu Abiko, Johanna Sofia Margareta Mattsson, Helena König et al. · 2014 · Clinical Cancer Research
  74. Prognostic and predictive biomarkers in lung cancer. A review
    Erik Thunnissen, Kimberly Van der Oord, Michael den Bakker · 2014 · Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin
  75. RADIA: RNA and DNA Integrated Analysis for Somatic Mutation Detection
    Amie Radenbaugh, Singer Ma, Adam D. Ewing, Joshua M. Stuart, Eric A. Collisson, Jingchun Zhu, David H. Haussler · 2014 · PLoS ONE
  76. Structural and functional analyses of the mammalian TIN2-TPP1-TRF2 telomeric complex
    Chunyi Hu, Rekha Rai, Chenhui Huang, Cayla Broton, Juanjuan Long, Ying Ming Xu, Jing Xue, Ming Lei, Sandy S. Chang, Yong Chen · 2017 · Cell Research
  77. Molecular heterogeneity of non-small cell lung carcinoma patient-derived xenografts closely reflect their primary tumors
    Dennis Y.Q. Wang, Nhu‐An Pham, Jiefei Tong, Shingo Sakashita, Ghassan Allo, Lucia Kim, Naoki Yanagawa, Vibha Raghavan, Yuhong Wei, Christine To et al. · 2016 · International Journal of Cancer
  78. STK11 (LKB1) mutations in metastatic NSCLC: Prognostic value in the real world
    Shire, Norah J., Klein, Alyssa B., Golozar, Asieh, Collins, Jenna M., Fraeman, Kathy H., Nordstrom, Beth L., McEwen, Robert, Hembrough, Todd, Rizvi, Naiyer A. · 2020 · PLOS ONE
  79. Resistance to Durvalumab and Durvalumab plus Tremelimumab Is Associated with Functional <i>STK11</i> Mutations in Patients with Non–Small Cell Lung Cancer and Is Reversed by STAT3 Knockdown
    Pore, Nabendu, Wu, Song, Standifer, Nathan, Jure-Kunkel, Maria, de los Reyes, Melissa, Shrestha, Yashaswi, Halpin, Rebecca, Rothstein, Raymond, Mulgrew, Kathy, Blackmore, Stephen et al. · 2021 · Cancer Discovery
  80. Individualized network-based drug repositioning infrastructure for precision oncology in the panomics era
    Feixiong Cheng, Huixiao Hong, Shengyong Yang, Yuquan Wei · 2016 · Briefings in Bioinformatics
  81. HP1γ Promotes Lung Adenocarcinoma by Downregulating the Transcription-Repressive Regulators NCOR2 and ZBTB7A
    Hunain Alam, Na Li, Shilpa S. Dhar, Sarah J. Wu, Jie Lv, Kaifu Chen, Elsa Renee Flores, Laura J. Baseler, Min Gyu Lee · 2018 · Cancer Research
  82. High-throughput screening with nucleosome substrate identifies small-molecule inhibitors of the human histone lysine methyltransferase NSD2
    Nathan P. Coussens, Stephen C. Kales, Mark J. Henderson, Olivia W. Lee, Kurumi Y. Horiuchi, Yuren Wang, Qing Chen, Ekaterina Kuznetsova, Jianghong Wu, Sirisha Chakka et al. · 2018 · Journal of Biological Chemistry
  83. Different prognostic impact ofSTK11mutations in non-squamous non-small-cell lung cancer
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  84. Lung cancer: potential targets for immunotherapy
    Éric Tartour, Laurence Zitvogel · 2013 · The Lancet Respiratory Medicine
  85. A cancer-testis non-coding RNA LIN28B-AS1 activates driver gene LIN28B by interacting with IGF2BP1 in lung adenocarcinoma
    Cheng Wang, Yayun Gu, Erbao Zhang, Kai Zhang, Na Qin, Juncheng Dai, Meng Zhu, Jia Liu, Kaipeng Xie, Yue Jiang et al. · 2018 · Oncogene
  86. Mutations in spliceosome genes and therapeutic opportunities in myeloid malignancies
    Justin Taylor, Stanley Chun-Wei Lee · 2019 · Genes Chromosomes and Cancer
  87. Lung Stem and Progenitor Cells in Tissue Homeostasis and Disease
    Kristen Tropea Leeman, Christine F. Brainson, Carla F. Kim · 2014 · Current topics in developmental biology/Current Topics in Developmental Biology
  88. Targeted next generation sequencing of parotid gland cancer uncovers genetic heterogeneity
    Inga Grünewald, Claudia Vollbrecht, Jeannine Meinrath, Moritz Friedo Meyer, Lukas Carl Heukamp, Uta Drebber, Alexander Quaas, Dirk Beutner, Karl‐Bernd Hüttenbrink, Eva Wardelmann et al. · 2015 · Oncotarget
  89. Oncogenic RIT1 mutations in lung adenocarcinoma
    Berger Ah, Marcin B. Imielinski, Fujiko F. Duke, Jeremiah A. Wala, Nathan O. Kaplan, Shi Gx, Douglas Andres, Matthew M. Meyerson · 2014 · Oncogene
  90. KRASoncogene in lung cancer: focus on molecularly driven clinical trials
    Emmanuelle Kempf, Benoı̂t Rousseau, Benjamin Besse, Luis G Paz-Ares · 2016 · European Respiratory Review
  91. Comprehensive molecular profiling of lung adenocarcinoma
    Eric S. Lander · 2014 · DSpace@MIT (Massachusetts Institute of Technology)
  92. Identification and Characterization of MCM3 as a Kelch-like ECH-associated Protein 1 (KEAP1) Substrate
    Kathleen M. Mulvaney, Jacob P. Matson, Priscila F. Siesser, Tigist Y. Tamir, Dennis Goldfarb, Timothy M. Jacobs, Erica W. Cloer, Joseph S. Harrison, Cyrus Vaziri, Jeanette Gowen Cook et al. · 2016 · Journal of Biological Chemistry
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    David R. Gandara, Tianhong Li, Primo N. Lara, Karen L. Kelly, Jonathan Wesley Riess, Mary Weber Redman, Philip C. Mack · 2013 · Clinical Lung Cancer
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    Octavio A. Romero, Montse Sánchez‐Céspedes · 2013 · Oncogene
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    Kanika S. Arora, Thinh Ngoc Tran, Yelena M. Kemel, Miika M. Mehine, Ying L. Liu, Subhiksha Nandakumar, Shaleigh A. Smith, Angela Rose Brannon, Irina Ostrovnaya, Konrad Hermann Stopsack et al. · 2022 · Cancer Discovery
  96. Molecular impact of mutations in RNA splicing factors in cancer
    Qian Zhang, Yuxi Ai, Omar Ibrahim Abdel-Wahab · 2024 · Molecular Cell
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    Helena Alexandra Yu, Maria E. Arcila, Megan Harlan Fleischut, Zsofia Kinga Stadler, Marc Ladanyi, Michael F. Berger, Mark E. Robson, Gregory J. Riely · 2014 · Journal of Thoracic Oncology
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    Qianhe Zhou, Adnan Derti, David A. Ruddy, Daniel P. Rakiec, Iris Kao, Michelle Lira, Veronica Gibaja, Homan Chan, Yi Yang, Junxia Min et al. · 2015 · Cancer Research
  99. Targeted therapies in development for non-small cell lung cancer
    Grace Kho Dy, Thanyanan Reungwetwattana · 2013 · Journal of Carcinogenesis
  100. Relapse-related long non-coding RNA signature to improve prognosis prediction of lung adenocarcinoma
    Meng Zhou, Wanying Xu, Yue X, Hengqiang Zhao, Zhenzhen Wang, Hongbo Shi, Liang Cheng, Jie Sun · 2016 · Oncotarget