β-Catenin-Driven Cancers Require a YAP1 Transcriptional Complex for Survival and Tumorigenesis
Rosenbluh, Joseph, Nijhawan, Deepak, Cox, Andrew G., Li, Xingnan, Neal, James T., Schafer, Eric J., Zack, Travis I., Wang, Xiaoxing, Tsherniak, Aviad, Schinzel, Anna C., Shao, Diane D., Schumacher, Steven E., Weir, Barbara A., Vazquez, Francisca, Cowley, Glenn S., Root, David E., Mesirov, Jill P., Beroukhim, Rameen, Kuo, Calvin J., Goessling, Wolfram, Hahn, William C.·2012·Cell
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- LINC00689 participates in proliferation, chemoresistance and metastasis via miR-31-5p/YAP/β-catenin axis in colorectal cancerYongliang Du, Yan Liang, Guang-Qing Shi, Yan Wei Cao, Juan Qiu, Yuan Li, Zhong Yong, Le Liu, Jian Li · 2020 · Experimental Cell Research
- A Driver Never Works Alone—Interplay Networks of Mutant p53, MYC, RAS, and Other Universal Oncogenic Drivers in Human CancerMaria Grzes, Magdalena Oroń, Zuzanna Staszczak, Akanksha Jaiswar, Magdalena Nowak-Niezgoda, Dawid Walerych · 2020 · Cancers
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- Tyrosine phosphorylation-mediated YAP1-TFAP2A interactions coordinate transcription and trastuzumab resistance in HER2+ breast cancerHailin Zou, Juan Luo, Yibo Guo, Liang Deng, Leli Zeng, Yihang Pan, Peng Li · 2024 · Drug Resistance Updates
- An optogenetic method for interrogating YAP1 and TAZ nuclear–cytoplasmic shuttlingAnna M. Dowbaj, Robert P. Jenkins, Daniel Williamson, John M. Heddleston, Alessandro Ciccarelli, Todd L. Fallesen, Klaus M. Hahn, Reuben D. O’Dea, John R. King, Marco Montagner et al. · 2021 · Journal of Cell Science
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- Long noncoding RNA DUXAP8 regulates proliferation and apoptosis of ovarian cancer cells via targeting miR-590-5pQingyou Meng, Zhongliang Li, Jiaxue Pan, Xiaorong Sun · 2020 · Human Cell
- Polyomavirus Small t Antigen Interacts with Yes-Associated Protein To Regulate Cell Survival and DifferentiationJustin H. Hwang, Arun T. Pores‐Fernando, Nathalie Faure, Shaida Andrabi, William C. Hahn, Brian S. Schaffhausen, Thomas M. Roberts · 2014 · Journal of Virology
- Cytokinesis Failure Leading to Chromosome Instability in v-Src-Induced OncogenesisYuji Nakayama, Shuhei Soeda, Masayoshi Ikeuchi, Keiko Kakae, Naoto Yamaguchi · 2017 · International Journal of Molecular Sciences
- YAP1 is essential for tumor growth and is a potential therapeutic target for EGFR-dependent lung adenocarcinomasTing‐Fang Lee, Yu-Chi Tseng, Wei‐Chin Chang, Yi‐Chen Chen, Yu-Rung Kao, Teh‐Ying Chou, Chao‐Chi Ho, Cheng‐Wen Wu · 2017 · Oncotarget
- Ascl2 activation by YAP1/KLF5 ensures the self-renewability of colon cancer progenitor cellsXiaolong Wei, Jun Ye, Yangyang Shang, Haoyuan Chen, Shanxi Liu, Li Liu, Rongquan Wang · 2017 · Oncotarget
- Scribble sub-cellular localization modulates recruitment of YES1 to regulate YAP1 phosphorylationZhao, Dongyu, Yin, Zhangyuan, Soellner, Matthew B., Martin, Brent R. · 2021 · Cell Chemical Biology
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- Aspirin attenuates YAP and β-catenin expression by promoting β-TrCP to overcome docetaxel and vinorelbine resistance in triple-negative breast cancerJi Ma, Zhenhai Fan, Qiulin Tang, Hongwei Xia, Tao Zhang, Feng Bi · 2020 · Cell Death and Disease
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- How Phosphofructokinase-1 Promotes PI3K and YAP/TAZ in Cancer: Therapeutic PerspectivesLuca Simula, Marco Alifano, Philippe Icard · 2022 · Cancers
- Epidermal YAP2-5SA-ΔC Drives β-Catenin Activation to Promote Keratinocyte Proliferation in Mouse Skin In VivoBassem Akladios, Veronica Mendoza‐Reinoso, Michael Susithiran Samuel, Edna C. Hardeman, Kiarash Khosrotehrani, Brian Key, Annemiek Beverdam · 2016 · Journal of Investigative Dermatology
- Hippo vs. Crab: tissue‐specific functions of the mammalian Hippo pathwayMiki Nishio, Tomohiko Maehama, Hiroki Goto, Keisuke Nakatani, Wakako Kato, Hirofumi Omori, Yosuke Miyachi, Hideru Togashi, Yohei Shimono, Akira Suzuki · 2017 · Genes to Cells
- Non-secreting pituitary tumours characterised by enhanced expression of YAP/TAZParaskevi Xekouki, Emily J. Lodge, Jakob Matschke, Alice Santambrogio, John Richard Apps, Ariane Sharif, Thomas S. Jacques, Simon J B Aylwin, Vincent Prévot, Ran Li et al. · 2018 · Endocrine Related Cancer
- The Hippo pathway: Horizons for innovative treatments of peripheral nerve diseasesM. Laura Feltri, Michael R. Weaver, Sophie Belin, Yannick Poitelon · 2021 · Journal of the Peripheral Nervous System
- Pharmacological regulators of Hippo pathway: Advances and challenges of drug developmentZhaobai Lao, Xin Chen, Bin Pan, Bin Fang, Wanlei Yang, Yu Qian · 2025 · The FASEB Journal
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- Molecular and Metabolic Reprogramming: Pulling the Strings Toward Tumor MetastasisAna Hipólito, Filipa Martins, Cindy Mendes, Filipa Lopes‐Coelho, Jacinta Serpa · 2021 · Frontiers in Oncology
- Hippo-YAP signaling in digestive system tumors.Feng Yin, Jixin Dong, Liang‐I Kang, Xiuli Liu · 2021 · PubMed Central
- Loss of HOXA10 causes endometrial hyperplasia progressing to endometrial cancerAnuradha Mishra, Nirmalya Ganguli, Subeer S. Majumdar, Deepak N. Modi · 2022 · Journal of Molecular Endocrinology
- The T-box transcription factor 3 is a promising biomarker and a key regulator of the oncogenic phenotype of a diverse range of sarcoma subtypesWillmer, T, Cooper, A, Sims, D, Govender, D, Prince, S · 2016 · Oncogenesis
- YES oncogenic activity is specified by its SH4 domain and regulates RAS/MAPK signaling in colon carcinoma cells.Fanny Dubois, Cédric Leroy, Valérie Simon, Christine Bénistant, Serge Roche · 2015 · Europe PMC (PubMed Central)
- A mouse SWATH-MS reference spectral library enables deconvolution of species-specific proteomic alterations in human tumour xenograftsLukáš Krásný, Philip J. Bland, Jessica Burns, Nadia Carvalho Lima, Peter T. Harrison, Laura Pacini, Mark L. Elms, Jian Ning, Víctor G. Martínez, Yi-Ru Yu et al. · 2020 · Disease Models & Mechanisms
- Expression of YAP1 and pSTAT3-S727 and their prognostic value in gliomaWei Sang, Jing Xue, Li-Ping Su, Gulinar Abulajiang, Qian Wang, Yang-Yang Zhai, Yanran Hu, Haixia Gao, Xinxia Li, Qiao-Xing Li et al. · 2020 · Journal of Clinical Pathology
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- PIN1 facilitates ubiquitin-mediated degradation of serine/threonine kinase 3 and promotes melanoma development via TAZ activationGaram Kim, Poshan Yugal Bhattarai, Sung‐Chul Lim, Jin Young Kim, Hong Seok Choi · 2020 · Cancer Letters
- Spatiotemporal model of cellular mechanotransduction via Rho and YAPJavor K. Novev, Mathias Luidor Heltberg, Mogens H. Jensen, Amin Doostmohammadi · 2021 · Integrative Biology
- TROP2 Represents a Negative Prognostic Factor in Colorectal Adenocarcinoma and Its Expression Is Associated with Features of Epithelial–Mesenchymal Transition and InvasivenessJiří Švec, Monika Šťastná, Lucie Janečková, Dušan Hrčkulák, Martina Vojtěchová, Jakub Onhajzer, Vı́tězslav Křı́ž, Kateřina Galušková, Eva Šloncová, Jan Kubovčiak et al. · 2022 · Cancers
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- Elevated MST1 leads to apoptosis via depletion of YAP1 in cardiomyocytes exposed to high glucoseSu, Dongmei, Li, Yanhua, Guan, Lina, Li, Qian, Shi, Cuige, Ma, Xu, Song, Yonghui · 2021 · Molecular Medicine
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- Emerging roles for the YAP/TAZ transcriptional regulators in brain tumour pathology and targeting optionsDimitrios Strepkos, Mariam Markouli, Kostas A. Papavassiliou, Athanasios G. Papavassiliou, Christina Piperi · 2021 · Neuropathology and Applied Neurobiology
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