Growth Differentiation Factor 11 Is a Circulating Factor that Reverses Age-Related Cardiac Hypertrophy

Loffredo, Francesco S., Steinhauser, Matthew L., Jay, Steven M., Gannon, Joseph, Pancoast, James R., Yalamanchi, Pratyusha, Sinha, Manisha, Dall’Osso, Claudia +12 more·2013·Cell

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  6. Association of growth differentiation factor 11/8, putative anti-ageing factor, with cardiovascular outcomes and overall mortality in humans: analysis of the Heart and Soul and HUNT3 cohorts
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  11. Systemic induction of senescence in young mice after single heterochronic blood exchange
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  12. GDF11 Protects against Endothelial Injury and Reduces Atherosclerotic Lesion Formation in Apolipoprotein E-Null Mice
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  13. Structural basis for potency differences between GDF8 and GDF11
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  14. Beyond antibodies: New affinity reagents to unlock the proteome
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  15. Protein damage, ageing and age-related diseases
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  16. Senescence and senolytics in cardiovascular disease: Promise and potential pitfalls
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  17. Exogenous GDF11 induces cardiac and skeletal muscle dysfunction and wasting
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  18. Regulation of inflammation as an anti‐aging intervention
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  19. Geroprotectors: A Unified Concept and Screening Approaches
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  21. Reduced Circulating GDF11 Is Unlikely Responsible for Age-Dependent Changes in Mouse Heart, Muscle, and Brain
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  22. Cell non-autonomous regulation of health and longevity
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    Nadine Biesemann, Luca Mendler, Astrid Wietelmann, Sven Hermann, Michael Andreas Schäfers, Marcus Krüger, Thomas Boettger, Thilo Borchardt, Thomas W Braun · 2014 · Circulation Research
  24. Regulation of GDF-11 and myostatin activity by GASP-1 and GASP-2
    Yun‐Sil Lee, Se‐Jin Lee · 2013 · Proceedings of the National Academy of Sciences
  25. Growth Differentiation Factor 11 treatment leads to neuronal and vascular improvements in the hippocampus of aged mice
    Ceren Ozek, Richard C. Krolewski, Sean M. Buchanan, Lee L. Rubin · 2018 · Scientific Reports
  26. Targeted myocardial delivery of GDF11 gene rejuvenates the aged mouse heart and enhances myocardial regeneration after ischemia–reperfusion injury
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  27. GDF11 promotes wound healing in diabetic mice via stimulating HIF-1ɑ-VEGF/SDF-1ɑ-mediated endothelial progenitor cell mobilization and neovascularization
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  28. A proteomic surrogate for cardiovascular outcomes that is sensitive to multiple mechanisms of change in risk
    Williams, Stephen A., Ostroff, Rachel, Hinterberg, Michael A., Coresh, Josef, Ballantyne, Christie M., Matsushita, Kunihiro, Mueller, Christian E., Walter, Joan, Jonasson, Christian, Holman, Rury R. et al. · 2022 · Science Translational Medicine
  29. Stem cell bioengineering: building from stem cell biology
    Mukul Tewary, Nika Shakiba, Peter W. Zandstra · 2018 · Nature Reviews Genetics
  30. Aging and Regeneration in Vertebrates
    Konstantinos Sousounis, Joelle Baddour, Panagiotis A. Tsonis · 2014 · Current topics in developmental biology/Current Topics in Developmental Biology
  31. Vinculin network–mediated cytoskeletal remodeling regulates contractile function in the aging heart
    Gaurav N. Kaushik, Alice Spenlehauer, Ayla O. Sessions, Adriana S. Trujillo, Alexander Fuhrmann, Zongming Fu, Vidya Venkatraman, Danielle Pohl, Jeremy Tuler, Mingyi Wang et al. · 2015 · Science Translational Medicine
  32. Advancements to the Axolotl Model for Regeneration and Aging
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  34. Extracellular vesicles and aging
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  35. Aging as an Epigenetic Phenomenon
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  46. Aging and brain rejuvenation as systemic events
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  48. Differentially expressed microRNAs in bone marrow mesenchymal stem cell-derived microvesicles in young and older rats and their effect on tumor growth factor-β1-mediated epithelial-mesenchymal transition in HK2 cells
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  49. Regulation of neurogenesis in the adult and aging brain
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  50. Supraphysiologic Administration of GDF11 Induces Cachexia in Part by Upregulating GDF15
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  51. Blood-Borne Revitalization of the Aged Brain
    Castellano, Joseph M., Kirby, Elizabeth D., Wyss-Coray, Tony · 2015 · JAMA Neurology
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    Jiangling Dong, Yanjun Dong, Zihong Chen, William E. Mitch, Liping Zhang · 2016 · Kidney International
  53. Age-associated pro-inflammatory remodeling and functional phenotype in the heart and large arteries
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  54. GDF11 promotes osteogenesis as opposed to MSTN, and follistatin, a MSTN/GDF11 inhibitor, increases muscle mass but weakens bone
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  55. The application of Aptamer in biomarker discovery
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  56. Role of growth differentiation factor 11 in development, physiology and disease
    Yonghui Zhang, Yong Shuai Wei, Dan Liu, Feng Liu, Xiaoshan Austin Li, Lianhong Pan, Yi Pang, Dilong Chen · 2017 · Oncotarget
  57. Proteomics in non-model organisms: a new analytical frontier
    M. Heck, Benjamin A. Neely · 2020 · Journal of Proteome Research
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  60. Anti-Aging Strategies Based on Cellular Reprogramming
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  62. The TGF-β Family inCaenorhabditis elegans
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  63. Large scale plasma proteomics identifies novel proteins and protein networks associated with heart failure development
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  65. Reversible Age-Related Phenotypes Induced during Larval Quiescence in C. elegans
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  66. Relationship of muscle function to circulating myostatin, follistatin and GDF11 in older women and men
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  67. Untitled work
    Harper · 2016 · 10.1161/circresaha.116.307962
  68. Adipose Tissue Senescence and Inflammation in Aging is Reversed by the Young Milieu
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  70. Ageing research: Blood to blood
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  71. Extracellular vesicles extracted from young donor serum attenuate inflammaging via partially rejuvenating aged T‐cell immunotolerance
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  76. Heterochronic parabiosis regulates the extent of cellular senescence in multiple tissues
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  77. Lack of evidence for GDF 11 as a rejuvenator of aged skeletal muscle satellite cells
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  78. Cellular cross-talks in the diseased and aging heart
    Julian U. G. Wagner, Stefanie Dimmeler · 2019 · Journal of Molecular and Cellular Cardiology
  79. Decline in muscle strength and running endurance in klotho deficient C57BL/6 mice
    Michael Phelps, Christina Pettan-Brewer, Warren Ladiges, Zipora Yablonka‐Reuveni · 2013 · Biogerontology
  80. Transcutaneous auricular vagus nerve stimulation regulates expression of growth differentiation factor 11 and activin-like kinase 5 in cerebral ischemia/reperfusion rats
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  81. Growth and differentiation factor 11 (GDF11): Functions in the regulation of erythropoiesis and cardiac regeneration
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  82. Young plasma reverses age‐dependent alterations in hepatic function through the restoration of autophagy
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  84. Growth Differentiation Factor-15 in Immunity and Aging
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  85. The Spectrum of Fundamental Basic Science Discoveries Contributing to Organismal Aging
    Joshua N. Farr, Maria Almeida · 2018 · Journal of Bone and Mineral Research
  86. Heart Failure with Preserved Ejection Fraction in Older Adults
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  89. Exogenous GDF11 attenuates non-canonical TGF-β signaling to protect the heart from acute myocardial ischemia–reperfusion injury
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  91. A revival of parabiosis in biomedical research
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