CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes

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Items 301–400 of 1,013

1. A CRISPR/Cas9-Based System for Reprogramming Cell Lineage Specification
   Syandan Chakraborty, HaYeun Ji, Ami M. Kabadi, Charles A. Gersbach, Nicolas Christoforou, Kam W. Leong · 2014 · Stem Cell Reports
2. Comparison of TALE designer transcription factors and the CRISPR/dCas9 in regulation of gene expression by targeting enhancers
   Xuefei Gao, Jason C.H. Tsang, Fortis Gaba, Donghai Wu, Liming Lu, Pentao Liu · 2014 · Nucleic Acids Research
3. Quantitative CRISPR interference screens in yeast identify chemical-genetic interactions and new rules for guide RNA design
   Justin Smith, Sundari Suresh, Ulrich Schlecht, Manhong Wu, Omar Wagih, Gary Peltz, Ronald Wayne Davis, Lars Michael Steinmetz, Leopold Parts, Robert P. St.Onge · 2016 · Genome biology
4. CRISPR Cpf1 proteins: structure, function and implications for genome editing
   Fatemeh Safari, Khadijeh Zare, Manica Negahdaripour, Mazyar Barekati‐Mowahed, Younes Ghasemi · 2019 · Cell & Bioscience
5. Mapping the genetic landscape of DNA double-strand break repair
   Jeffrey A. Hussmann, Ling Jia, Purnima Ravisankar, Jun Yan, Ann Cirincione, Albert Xu, Danny Simpson, Dian Yang, Anne Bothmer, Cecilia Cotta‐Ramusino et al. · 2021 · Cell
6. CRISPR interference as a titratable, trans-acting regulatory tool for metabolic engineering in the cyanobacterium Synechococcus sp. strain PCC 7002
   Gina C. Gordon, Travis C. Korosh, Jeffrey C. Cameron, Andrew L. Markley, Matthew B. Begemann, Brian F. Pfleger · 2016 · Metabolic Engineering
7. HOTTIP lncRNA Promotes Hematopoietic Stem Cell Self-Renewal Leading to AML-like Disease in Mice
   Huacheng Luo, Ganqian Zhu, Jianfeng Xu, Qian Lai, Bowen Yan, Ying Guo, Tsz Kan Fung, Bernd B. Zeisig, Ya Cui, Jie Zha et al. · 2019 · Cancer Cell
8. Gene editing and CRISPR in the clinic: current and future perspectives
   Matthew P. Hirakawa, Raga Krishnakumar, Jerilyn A. Timlin, James P. Carney, Kimberly S. Butler · 2020 · Bioscience Reports
9. CRISPR-Cas Tools and Their Application in Genetic Engineering of Human Stem Cells and Organoids
   Delilah F. G. Hendriks, Hans C. Clevers, Benedetta Artegiani · 2020 · Cell stem cell
10. A CRISPR toolbox to study virus–host interactions
    Andreas S. Puschnik, Karim Majzoub, Yaw Shin Ooi, Jan E. Carette · 2017 · Nature Reviews Microbiology
11. High-Level dCas9 Expression Induces Abnormal Cell Morphology in Escherichia coli
    Suhyung Cho, Donghui Choe, Eun‐Ju Lee, Sun Chang Kim, Bernhard Ørn Palsson, Byung‐Kwan Cho · 2018 · ACS Synthetic Biology
12. Systematic perturbation of retroviral LTRs reveals widespread long-range effects on human gene regulation
    Daniel Fuentes, Tomek Swigut, Joanna Wysocka · 2018 · eLife
13. Delivery and Specificity of CRISPR/Cas9 Genome Editing Technologies for Human Gene Therapy
    Jennifer L. Gori, Patrick D. Hsu, Morgan L. Maeder, Shen Shen, G. Grant Welstead, David A. Bumcrot · 2015 · Human Gene Therapy
14. Progress and Prospects of CRISPR/Cas Systems in Insects and Other Arthropods
    Dan Sun, Zhaojiang Guo, Yong Liu, Youjun Zhang · 2017 · Frontiers in Physiology
15. Platforms for Investigating LncRNA Functions
    John Lalith Charles Richard, Pieter J.A. Eichhorn · 2018 · SLAS TECHNOLOGY
16. Durable and efficient gene silencing in vivo by hit-and-run epigenome editing
    Martino Alfredo Cappelluti, Valeria Mollica Poeta, Sara Valsoni, Piergiuseppe Quarato, S. Merlin, I. Merelli, A. Lombardo · 2024 · Nature
17. Implementation of the CRISPR-Cas9 system in fission yeast
    Jake Z. Jacobs, Keith M. Ciccaglione, Vincent Tournier, Mikel Zaratiegui · 2014 · Nature Communications
18. Genome Editing in Plants: Exploration of Technological Advancements and Challenges
    Sanskriti Vats, Surbhi Kumawat, Virender Kumar, Gunvant Patil, Trupti Joshi, Humira Sonah, Tilak Raj Sharma, Rupesh Kailasrao Deshmukh · 2019 · Cells
19. Efficient programmable gene silencing by Cascade
    Devashish Rath, Lina Amlinger, Mirthe Hoekzema, Praneeth Reddy Devulapally, Magnus Lundgren · 2014 · Nucleic Acids Research
20. Paired Design of dCas9 as a Systematic Platform for the Detection of Featured Nucleic Acid Sequences in Pathogenic Strains
    Yihao Zhang, Long Qian, Weijia Wei, Yu Wang, Beining Wang, Pingping Lin, Wenchao Liu, Luze Xu, Xiang Li, Dongming Liu et al. · 2016 · ACS Synthetic Biology
21. Controlling CRISPR-Cas9 with ligand-activated and ligand-deactivated sgRNAs
    Kale Kundert, James E. Lucas, Kyle E. Watters, Christof Fellmann, Andrew H. Ng, Benjamin Murray Heineike, Christina M. Fitzsimmons, Benjamin L. Oakes, Jiuxin Qu, Neha K. Prasad et al. · 2019 · Nature Communications
22. Spatiotemporal control of CRISPR/Cas9 gene editing
    Chenya Zhuo, Jiabin Zhang, Jung‐Hwan Lee, Ju Jiao, Du Cheng, Li Liu, Hae‐Won Kim, Yu Tao, Mingqiang Li · 2021 · Signal Transduction and Targeted Therapy
23. Recent progress in genetically modified microalgae for enhanced carbon dioxide sequestration
    Bahram Barati, Kuo Zeng, Jan Baeyens, Shuang Wang, Min Addy, Sook Yee Gan, Abdelfatah Abomohra · 2020 · Biomass and Bioenergy
24. Expanding the CRISPR imaging toolset withStaphylococcus aureusCas9 for simultaneous imaging of multiple genomic loci
    Baohui Chen, Jeffrey Hu, Ricardo Almeida, Harrison Liu, Sanjeev Balakrishnan, Christian Covill‐Cooke, Wendell A. Lim, Bo Huang · 2016 · Nucleic Acids Research
25. Rational designs of in vivo CRISPR-Cas delivery systems
    Cong‐Fei Xu, Guojun Chen, Ying‐Li Luo, Yue Zhang, Gui Zhao, Zi-Dong Lu, Anna Czarna, Zhen Gu, Jun Wang · 2019 · Advanced Drug Delivery Reviews
26. Pooled Knockin Targeting for Genome Engineering of Cellular Immunotherapies
    Roth, Theodore L., Li, P. Jonathan, Blaeschke, Franziska, Nies, Jasper F., Apathy, Ryan, Mowery, Cody, Yu, Ruby, Nguyen, Michelle L.T., Lee, Youjin, Truong, Anna et al. · 2020 · Cell
27. Dynamics and Context-Dependent Roles of DNA Methylation
    Christina M. Ambrosi, Massimiliano Manzo, Tuncay Baubec · 2017 · Journal of Molecular Biology
28. Parallel shRNA and CRISPR-Cas9 screens enable antiviral drug target identification
    Richard M. Deans, D. Morgens, Ayşe Ökesli, S. Pillay, M. Horlbeck, M. Kampmann, Luke A. Gilbert, Amy Li, Roberto Mateo, Mark Smith et al. · 2016 · Nature Chemical Biology
29. Structural Mechanism of a Rag GTPase Activation Checkpoint by the Lysosomal Folliculin Complex
    R. Lawrence, S. Fromm, Yang-Xue Fu, A. Yokom, Do Jin Kim, Ashley M. Thelen, Lindsey N. Young, Chun-Yan Lim, Avi J. Samelson, J. Hurley et al. · 2019 · Science
30. Inhibition of NGLY1 Inactivates the Transcription Factor Nrf1 and Potentiates Proteasome Inhibitor Cytotoxicity
    Frederick M. Tomlin, Ulla I. M. Gerling‐Driessen, Yi-Chang Liu, Ryan A. Flynn, Janakiram Reddy Vangala, Christian Stephan Lentz, Sandra Clauder-Muenster, Petra Jakob, William F. Mueller, Diana Ordoñez‐Rueda et al. · 2017 · ACS Central Science
31. Application of CRISPR/Cas9-Based Gene Editing in HIV-1/AIDS Therapy
    Qiaoqiao Xiao, Deyin Guo, Shuliang Chen · 2019 · Frontiers in Cellular and Infection Microbiology
32. Development of CRISPR-Cas systems for genome editing and beyond
    F. Zhang · 2019 · Quarterly Reviews of Biophysics
33. Insert, remove or replace: A highly advanced genome editing system using CRISPR/Cas9
    Stanislaus Antony Ceasar, Vinothkumar Rajan, Sergey V. Prykhozhij, Jason N. Berman, Savarimuthu Ignacimuthu S.J. · 2016 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
34. CRISPR/Cas9 Immune System as a Tool for Genome Engineering
    Magdalena Hryhorowicz, Daniel Lipiński, Joanna Zeyland, Ryszard Słomski · 2016 · Archivum Immunologiae et Therapiae Experimentalis
35. A Muscle-Specific Enhancer RNA Mediates Cohesin Recruitment and Regulates Transcription In trans
    Pei-Fang Tsai, Stefania Dell’Orso, Joseph Rodriguez, Karinna O. Vivanco, Kyung-Dae Ko, Kan Jiang, Aster H. Juan, Aishe A. Sarshad, Laura Vian, Michelle D Tran et al. · 2018 · Molecular Cell
36. CRISPR–Cas: a tool for cancer research and therapeutics
    Hao Yin, Wen Xue, Daniel G. Anderson · 2019 · Nature Reviews Clinical Oncology
37. CRISPR/Cas: a Nobel Prize award-winning precise genome editing technology for gene therapy and crop improvement
    Chao Li, Eleanor J. Brant, Hikmet Budak, Baohong Zhang · 2021 · Journal of Zhejiang University SCIENCE B
38. Conditionally Stabilized dCas9 Activator for Controlling Gene Expression in Human Cell Reprogramming and Differentiation
    Diego Balboa, Jere Weltner, Solja Eurola, Ras Trokovic, Kirmo Wartiovaara, Timo Otonkoski · 2015 · Stem Cell Reports
39. RNA-guided transcriptional silencing in vivo with S. aureus CRISPR-Cas9 repressors
    Pratiksha I. Thakore, Jennifer B. Kwon, Christopher E. Nelson, Douglas C. Rouse, Matthew P. Gemberling, Matthew L. Oliver, Charles A. Gersbach · 2018 · Nature Communications
40. Recent Progress in CRISPR/Cas9 Technology
    Yue Mei, Yan Wang, Huiqian Chen, Zhong Sheng Sun, Xing‐Da Ju · 2016 · Journal of genetics and genomics/Journal of Genetics and Genomics
41. CRISPR/Cas system for yeast genome engineering: advances and applications
    Vratislav Šťovíček, Carina Holkenbrink, Irina Borodina · 2017 · FEMS Yeast Research
42. Cohesin-Dependent and -Independent Mechanisms Mediate Chromosomal Contacts between Promoters and Enhancers
    Thiecke, Michiel J., Wutz, Gordana, Muhar, Matthias, Tang, Wen, Bevan, Stephen, Malysheva, Valeriya, Stocsits, Roman, Neumann, Tobias, Zuber, Johannes, Fraser, Peter et al. · 2020 · Cell Reports
43. A catalogue of biochemically diverse CRISPR-Cas9 orthologs
    Giedrius Gasiūnas, Joshua K. Young, Tautvydas Karvelis, Darius Kazlauskas, Tomas Urbaitis, Monika Jasnauskaitė, Mantvyda M. Grusyte, Sushmitha Paulraj, Po-Hao Wang, Zhenglin Hou et al. · 2020 · Nature Communications
44. Advances in CRISPR therapeutics
    Michael Chavez, Xinyi Chen, Paul B. Finn, Lei S. Qi · 2022 · Nature Reviews Nephrology
45. Multidimensional control of therapeutic human cell function with synthetic gene circuits
    Hui-Shan Li, Divya V. Israni, Keith A. Gagnon, Kok Ann Gan, Michael H. Raymond, Jeffry D. Sander, Kole T. Roybal, J. Keith Joung, Wilson W. Wong, Ahmad S. Khalil · 2022 · Science
46. Design of a programmable biosensor-CRISPRi genetic circuits for dynamic and autonomous dual-control of metabolic flux in Bacillus subtilis
    Yaokang Wu, Taichi Chen, Yanfeng Liu, Rongzhen Tian, Xueqin Lv, Jianghua Li, Guocheng Du, Jian Chen, Rodrigo Ledesma‐Amaro, Long Liu · 2019 · Nucleic Acids Research
47. LRP8-Reelin-regulated neuronal enhancer signature underlying learning and memory formation
    Telese, Francesca, Ma, Qi, Perez, Patricia Montilla, Notani, Dimple, Oh, Soohwan, Li, Wenbo, Comoletti, Davide, Ohgi, Kenneth A., Taylor, Havilah, Rosenfeld, Michael G. · 2015 · Neuron
48. Evolutionary Convergence of Pathway-Specific Enzyme Expression Stoichiometry
    Jean‐Benoît Lalanne, James Taggart, Monica S. Guo, Lydia Herzel, Ariel Schieler, Gene‐Wei Li · 2018 · Cell
49. CRISPR/dCas9 Tools: Epigenetic Mechanism and Application in Gene Transcriptional Regulation
    Ruijie Cai, Runyu Lv, Xin’e Shi, Gongshe Yang, Jianjun Jin · 2023 · International Journal of Molecular Sciences
50. Linking RNA biology to lncRNAs
    Loyal A. Goff, John L. Rinn · 2015 · Genome Research
51. The lncRNA TP73-AS1 is linked to aggressiveness in glioblastoma and promotes temozolomide resistance in glioblastoma cancer stem cells
    Gal Mazor, Liron Levin, Daniel J. Picard, Ulvi Ahmadov, Helena Carén, Arndt Borkhardt, Guido Reifenberger, Gabriel Leprivier, Marc Remke, Barak Rotblat · 2019 · Cell Death and Disease
52. PRMT5 methylome profiling uncovers a direct link to splicing regulation in acute myeloid leukemia
    Aliaksandra Radzisheuskaya, Pavel V. Shliaha, Vasily V. Grinev, Eugenia Lorenzini, Sergey I. Kovalchuk, Daria Shlyueva, Vladimir Gorshkov, Ronald C. Hendrickson, Ole Nørregaard Jensen, Kristian Helin · 2019 · Nature Structural & Molecular Biology
53. Genome editing of crops: A renewed opportunity for food security
    Fawzy Georges, Heather Ray · 2017 · GM crops & food
54. Functional validation of cadherin as a receptor of Bt toxin Cry1Ac in Helicoverpa armigera utilizing the CRISPR/Cas9 system
    Jing Wang, Haonan Zhang, Huidong Wang, Shan Zhao, Yayun Zuo, Yihua Yang, Yidong Wu · 2016 · Insect Biochemistry and Molecular Biology
55. The importance of DNA methylation of exons on alternative splicing
    Ronna Shayevitch, Dan Askayo, Ifat Keydar, Gil Ast · 2018 · RNA
56. 3′ end formation of pre-mRNA and phosphorylation of Ser2 on the RNA polymerase II CTD are reciprocally coupled in human cells
    Lee Davidson, Lisa Muniz, Steven West · 2014 · Genes & Development
57. Ezh2-dCas9 and KRAB-dCas9 enable engineering of epigenetic memory in a context-dependent manner
    Henriette O’Geen, Sofie L. Bates, Sakereh Carter, Karly Nisson, Julian A. N. M. Halmai, Kyle D. Fink, Suhn K. Rhie, Peggy Farnham, David Jay Segal · 2019 · Epigenetics & Chromatin
58. CRISPR-Based Chromatin Remodeling of the Endogenous Oct4 or Sox2 Locus Enables Reprogramming to Pluripotency
    Peng Liu, Meng Chen, Yanxia Liu, Lei S. Qi, Sheng Ding · 2018 · Cell stem cell
59. Applications of CRISPR/Cas System to Bacterial Metabolic Engineering
    Suhyung Cho, Jongoh Shin, Byung‐Kwan Cho · 2018 · International Journal of Molecular Sciences
60. CRISPR‐based genome editing and expression control systems in Clostridium acetobutylicum and Clostridium beijerinckii
    Qi Li, Jun Chen, Nigel Peter Minton, Ying Zhang, Zhiqiang Wen, Jinle Liu, Haifeng Yang, Zhe Zeng, Xiaodan Ren, Junjie Yang et al. · 2016 · Biotechnology Journal
61. Large, Diverse Population Cohorts of hiPSCs and Derived Hepatocyte-like Cells Reveal Functional Genetic Variation at Blood Lipid-Associated Loci
    Evanthia E. Pashos, YoSon Park, Xiao Wang, Avanthi Raghavan, Wenli Yang, Deepti Abbey, Derek Peters, Juan Arbelaez, Mayda Hernandez, Nicolas Kuperwasser et al. · 2017 · Cell stem cell
62. Transgenic Breeding Approaches for Improving Abiotic Stress Tolerance: Recent Progress and Future Perspectives
    Ali Anwar, Ju‐Kon Kim · 2020 · International Journal of Molecular Sciences
63. Leveraging Physiology for Precision Drug Delivery
    Sun, Wujin, Hu, Quanyin, Ji, Wenyan, Wright, Grace, Gu, Zhen · 2017 · Physiological Reviews
64. Advances in CRISPR-Cas9 genome engineering: lessons learned from RNA interference
    Rodolphe Barrangou, Amanda Birmingham, Stefan Wiemann, Roderick L. Beijersbergen, Veit Hornung, Anja van Brabant Smith · 2015 · Nucleic Acids Research
65. Casilio: a versatile CRISPR-Cas9-Pumilio hybrid for gene regulation and genomic labeling
    Albert W. Cheng, Nathaniel Jillette, Phoebe L. Lee, Dylan M. Plaskon, Yasuhiro Fujiwara, Wenbo Wang, Aziz Taghbalout, Haoyi Wang · 2016 · Cell Research
66. Genetic interaction mapping in mammalian cells using CRISPR interference
    Dan Du, Assen Roguev, David Ezra Gordon, Meng Chen, Sihan Chen, Michael Shales, John Paul Shen, Trey E. Ideker, Prashant Mali, Lei S. Qi et al. · 2017 · Nature Methods
67. Implementing CRISPR-Cas technologies in conventional and non-conventional yeasts: Current state and future prospects
    Hana Raschmanová, Astrid Weninger, Anton Glieder, Karin Kovar, Thomas J. Vogl · 2018 · Biotechnology Advances
68. Titrating gene expression using libraries of systematically attenuated CRISPR guide RNAs
    Jost, Marco, Santos, Daniel A., Saunders, Reuben A., Horlbeck, Max A., Hawkins, John S., Scaria, Sonia M., Norman, Thomas M., Hussmann, Jeffrey A., Liem, Christina R., Gross, Carol A. et al. · 2020 · Nature Biotechnology
69. CRISPR-based functional genomics for neurological disease
    Kampmann, Martin · 2020 · Nature Reviews Neurology
70. CRISPR/gRNA-directed synergistic activation mediator (SAM) induces specific, persistent and robust reactivation of the HIV-1 latent reservoirs
    Yonggang Zhang, Chaoran Yin, Ting Zhang, Fang Li, Wensheng Yang, Rafal Kaminski, Philip Regis Fagan, Raj Putatunda, Won‐Bin Young, Kamel Khalili et al. · 2015 · Scientific Reports
71. A Precision Medicine Approach to the Rescue of Function on Malignant Calmodulinopathic Long-QT Syndrome
    Worawan B. Limpitikul, Ivy E. Dick, David J. Tester, Nicole J. Boczek, Pattraranee Limphong, Wanjun Yang, Myoung Hyun Choi, Jennifer Babich, Deborah A. DiSilvestre, Ronald J. Kanter et al. · 2016 · Circulation Research
72. Exploring the potential of genome editing CRISPR-Cas9 technology
    Vijai Singh, Darren Braddick, Pawan Kumar Dhar · 2016 · Gene
73. Brd4 and P300 Confer Transcriptional Competency during Zygotic Genome Activation
    Shun Hang Chan, Yin Tang, Liyun Miao, Hiba Darwich‐Codore, Charles E. Vejnar, Jean-Denis Beaudoin, Damir Musaev, Juan Pablo Fernández, Maria D.J. Benitez, Ariel Bazzini et al. · 2019 · Developmental Cell
74. The RNA Atlas expands the catalog of human non-coding RNAs
    Lorenzi, Lucia, Chiu, Hua-Sheng, Avila Cobos, Francisco, Gross, Stephen, Volders, Pieter-Jan, Cannoodt, Robrecht, Nuytens, Justine, Vanderheyden, Katrien, Anckaert, Jasper, Lefever, Steve et al. · 2021 · Nature Biotechnology
75. In Situ Gene Therapy via AAV-CRISPR-Cas9-Mediated Targeted Gene Regulation
    Moreno, Ana M., Fu, Xin, Zhu, Jie, Katrekar, Dhruva, Shih, Yu-Ru V., Marlett, John, Cabotaje, Jessica, Tat, Jasmine, Naughton, John, Lisowski, Leszek et al. · 2018 · Molecular Therapy
76. Structural basis for the altered PAM specificities of engineered CRISPR-cas9
    Hirano, Seiichi, Nishimasu, Hiroshi, Ishitani, Ryuichiro, Nureki, Osamu · 2016 · Molecular Cell
77. A microRNA-inducible CRISPR–Cas9 platform serves as a microRNA sensor and cell-type-specific genome regulation tool
    Xiwen Wang, Lu‐Feng Hu, Jing Hao, Le‐Qi Liao, Ya-Tzu Chiu, Ming Shi, Yangming Wang · 2019 · Nature Cell Biology
78. A renaissance in RNA synthetic biology: new mechanisms, applications and tools for the future
    James Chappell, Kyle E. Watters, Melissa K. Takahashi, Julius B. Lucks · 2015 · Current Opinion in Chemical Biology
79. Rapid and reversible epigenome editing by endogenous chromatin regulators
    Simon M. G. Braun, Jacob G. Kirkland, Emma J. Chory, Dylan Husmann, Joseph P. Calarco, Gerald R. Crabtree · 2017 · Nature Communications
80. CRISPR interference-based specific and efficient gene inactivation in the brain
    Yi Zheng, Wei Shen, Jian Zhang, Bo Yang, Yaonan Liu, Huihui Qi, Xia Yu, Si‐Yao Lu, Yun Chen, Yuzhou Xu et al. · 2018 · Nature Neuroscience
81. EBV Noncoding RNA Binds Nascent RNA to Drive Host PAX5 to Viral DNA
    Nara Lee, Walter N. Moss, Therese A. Yario, JOAN ARGETSINGER STEITZ · 2015 · Cell
82. Synthetic far-red light-mediated CRISPR-dCas9 device for inducing functional neuronal differentiation
    Jiawei Shao, Meiyan Wang, Guiling Yu, Sucheng Zhu, Yuanhuan Yu, Boon Chin Heng, Jiali Wu, Haifeng Ye · 2018 · Proceedings of the National Academy of Sciences
83. Current status and perspectives of genome editing technology for microalgae
    Jeon, Seungjib, Lim, Jong-Min, Lee, Hyung-Gwan, Shin, Sung-Eun, Kang, Nam Kyu, Park, Youn-Il, Oh, Hee-Mock, Jeong, Won-Joong, Jeong, Byeong-ryool, Chang, Yong Keun · 2017 · Biotechnology for Biofuels
84. CRISPR-Cas9/Cas12a biotechnology and application in bacteria
    Ruilian Yao, Di Liu, Xiao Jia, Yuan Zheng, Wei Yong Liu, Yi Xiao · 2018 · Synthetic and Systems Biotechnology
85. Optimizing sgRNA position markedly improves the efficiency of CRISPR/dCas9-mediated transcriptional repression
    Aliaksandra Radzisheuskaya, Daria Shlyueva, I. Müller, K. Helin · 2016 · Nucleic Acids Research
86. Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors
    Joseph M. Replogle, Jessica L. Bonnar, Angela N. Pogson, Christina R. Liem, Nolan K. Maier, Yufang Ding, Baylee J. Russell, Xingren Wang, Kun Leng, Alina Guna et al. · 2022 · eLife
87. Revolutionizing plant biology: multiple ways of genome engineering by CRISPR/Cas
    Simon Schiml, Holger Puchta · 2016 · Plant Methods
88. CRISPR/Cas9 in insects: Applications, best practices and biosafety concerns
    Clauvis Nji Tizi Taning, Benigna Van Eynde, Na Yu, Sanyuan Ma, Guy J. Smagghe · 2017 · Journal of Insect Physiology
89. Rewiring human cellular input–output using modular extracellular sensors
    Kelly A. Schwarz, Nichole M. Daringer, Taylor B. Dolberg, Joshua N. Leonard · 2016 · Nature Chemical Biology
90. Genome and metabolic engineering in non-conventional yeasts: Current advances and applications
    Ann‐Kathrin Löbs, Cory Schwartz, Ian R. Wheeldon · 2017 · Synthetic and Systems Biotechnology
91. Programmable base editing of mutated TERT promoter inhibits brain tumour growth
    Xinjian Li, Xu Qian, Bin Wang, Yan Xia, Yanhua Zheng, Linyong Du, Daqian Xu, Dongming Xing, Ronald Anthony DePinho, Zhimin Lu · 2020 · Nature Cell Biology
92. Mitigation of off-target toxicity in CRISPR-Cas9 screens for essential non-coding elements
    Josh Tycko, Michael Wainberg, Georgi K. Marinov, Oana Ursu, Gaelen T. Hess, Braeden K. Ego, Aradhana, Amy Li, Alisa Truong, Alexandro E. Trevino et al. · 2019 · Nature Communications
93. CRISPR technologies for bacterial systems: Current achievements and future directions
    Kyeong Rok Choi, Sang Yup Lee · 2016 · Biotechnology Advances
94. Anti-CRISPR-mediated control of gene editing and synthetic circuits in eukaryotic cells
    Muneaki Nakamura, Prashanth Srinivasan, Michael Chavez, Matthew Carter, Antonia A. Dominguez, Marie F. La Russa, Matthew B. Lau, Timothy R. Abbott, Xiaoshu Xu, Dehua Zhao et al. · 2019 · Nature Communications
95. KnockTF: a comprehensive human gene expression profile database with knockdown/knockout of transcription factors
    Feng, Chenchen, Song, Chao, Liu, Yuejuan, Qian, Fengcui, Gao, Yu, Ning, Ziyu, Wang, Qiuyu, Jiang, Yong, Li, Yanyu, Li, Meng et al. · 2020 · Nucleic Acids Research
96. Direct activation of human and mouse Oct4 genes using engineered TALE and Cas9 transcription factors
    Jiabiao Hu, Yong Lei, Wing-Ki Wong, Senquan Liu, Kai-Chuen Lee, Xijing He, Wenxing You, Rui Zhou, Jun‐tao Guo, Xiongfong Chen et al. · 2014 · Nucleic Acids Research
97. HOTTIP-dependent R-loop formation regulates CTCF boundary activity and TAD integrity in leukemia
    Huacheng Luo, Ganqian Zhu, Melanie A. Eshelman, Tsz Kan Fung, Qian Lai, Fei Wang, Bernd B. Zeisig, Julia Lesperance, Xiaoyan Ma, Chen Shi et al. · 2022 · Molecular Cell
98. Targeted DNA integration in human cells without double-strand breaks using CRISPR-associated transposases
    George D. Lampe, Rebeca T. King, Tyler S. Halpin-Healy, Sanne E. Klompe, Marcus I. Hogan, Phuc Leo H. Vo, Stephen Tang, Alejandro Chavez, Samuel H. Sternberg · 2023 · Nature Biotechnology
99. CRISPR-GPT for agentic automation of gene-editing experiments
    Yuan-Hao Qu, Kai-Xuan Huang, Ming Yin, Kang-Hong Zhan, Dyllan Liu, Di Yin, Henry C. Cousins, William A. Johnson, Xiao-Tong Wang, Mihir M. Shah et al. · 2024 · Nature Biomedical Engineering
100. Structure and specificity of the RNA-guided endonuclease Cas9 during DNA interrogation, target binding and cleavage
     Eric A. Josephs, D. Dewran Koçak, Christopher J. Fitzgibbon, Joshua McMenemy, Charles A. Gersbach, Piotr E. Marszałek · 2015 · Nucleic Acids Research