CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes

Gilbert, Luke A., Larson, Matthew H., Morsut, Leonardo, Liu, Zairan, Brar, Gloria A., Torres, Sandra E., Stern-Ginossar, Noam, Brandman, Onn +5 more·2013·Cell

Cited by (1,013)

Items 201–300 of 1,013

  1. Genome modification by CRISPR /Cas9
    Yuanwu Ma, Lianfeng Zhang, Xingxu Huang · 2014 · FEBS Journal
  2. The CRISPR/Cas Genome-Editing Tool: Application in Improvement of Crops
    Khatodia, Surender, Bhatotia, Kirti, Passricha, Nishat, Khurana, S. M. P., Tuteja, Narendra · 2016 · Frontiers in Plant Science
  3. Combinatorial optimization of CRISPR/Cas9 expression enables precision genome engineering in the methylotrophic yeast Pichia pastoris
    Astrid Weninger, Anna-Maria Hatzl, Christian Schmid, Thomas J. Vogl, Anton Glieder · 2016 · Journal of Biotechnology
  4. Repurposing CRISPR-Cas12b for mammalian genome engineering
    Fei Teng, Tongtong Cui, Guihai Feng, Lu Guo, Kai Xu, Qingqin Gao, Tianda Li, Jing Li, Qi Zhou, Wei Li · 2018 · Cell Discovery
  5. Corynebacterium glutamicum Metabolic Engineering with CRISPR Interference (CRISPRi)
    Sara Cleto, Jaide Vold Korgaard Jensen, Volker F. Wendisch, Timothy K. Lu · 2016 · ACS Synthetic Biology
  6. Lipid peroxidation increases membrane tension, Piezo1 gating, and cation permeability to execute ferroptosis
    Yusuke Hirata, Ruiqi Cai, Allen Volchuk, Benjamin Ethan Steinberg, Yoshiro Saito, Atsushi Matsuzawa, Sergio Grinstein, Spencer A. Freeman · 2023 · Current Biology
  7. Guide RNA Functional Modules Direct Cas9 Activity and Orthogonality
    Alexandra E. Briner, Paul D. Donohoue, Ahmed A. Gomaa, Kurt Selle, Euan M. Slorach, Christopher H. Nye, R.E. Haurwitz, Chase L. Beisel, Andrew P. May, Rodolphe Barrangou · 2014 · Molecular Cell
  8. CRISPR technologies for genome, epigenome and transcriptome editing
    Lukas Villiger, Julia Joung, Luke W. Koblan, Jonathan S. Weissman, Omar O. Abudayyeh, Jonathan S. Gootenberg · 2024 · Nature Reviews Molecular Cell Biology
  9. The roles of CRISPR–Cas systems in adaptive immunity and beyond
    Rodolphe Barrangou · 2015 · Current Opinion in Immunology
  10. Non-coding RNA: a new frontier in regulatory biology
    Xiang‐Dong Fu · 2014 · National Science Review
  11. Rewritable multi-event analog recording in bacterial and mammalian cells
    Weixin Tang, David R. Liu · 2018 · Science
  12. Delivery of CRISPR-Cas tools for in vivo genome editing therapy: Trends and challenges
    Taha, Eman A., Lee, Joseph, Hotta, Akitsu · 2022 · Journal of Controlled Release
  13. Circ-HuR suppresses HuR expression and gastric cancer progression by inhibiting CNBP transactivation
    Feng Yang, Anpei Hu, Dan Li, Jianqun Wang, Yanhua Guo, Yang Liu, Hongjun Li, Yajun Chen, Xiaojing Wang, Kai Huang et al. · 2019 · Molecular Cancer
  14. Improving prime editing with an endogenous small RNA-binding protein
    Jun Yan, Paul Oyler-Castrillo, Purnima Ravisankar, Carl C. Ward, Sébastien Levesque, Yangwode Jing, Danny Simpson, Anqi Zhao, Hui zi Li, Weihao Yan et al. · 2024 · Nature
  15. Multi‐input CRISPR/Cas genetic circuits that interface host regulatory networks
    Alec A. K. Nielsen, Christopher A. Voigt · 2014 · Molecular Systems Biology
  16. Long Noncoding RNA Discovery in Cardiovascular Disease
    Tamer Sallam, Jaspreet Sandhu, Peter Tontonoz · 2018 · Circulation Research
  17. Non-coding RNAs in cancer: platforms and strategies for investigating the genomic “dark matter”
    Katia Grillone, Caterina Riillo, Francesca Scionti, Roberta Rocca, Giuseppe Tradigo, Pietro Hiram Guzzi, Stefano Alcaro, Maria Teresa Di Martino, Pierosandro Tagliaferri, Pierfrancesco Tassone · 2020 · Journal of Experimental & Clinical Cancer Research
  18. Interrogation of enhancer function by enhancer-targeting CRISPR epigenetic editing
    Kailong Li, Yuxuan Liu, Hui Cao, Yuannyu Zhang, Zhimin Gu, Xin Liu, Andy Yu, Pranita Kaphle, Kathryn E. Dickerson, Min Ni et al. · 2020 · Nature Communications
  19. High-content CRISPR screening
    Christoph Bock, Paul Datlinger, Florence M. Chardon, Matthew A. Coelho, Matthew B. Dong, Keith A. Lawson, Tian Lu, Laetitia Maroc, Thomas M. Norman, Bicna Song et al. · 2022 · Nature Reviews Methods Primers
  20. Partial DNA-guided Cas9 enables genome editing with reduced off-target activity
    Yin, Hao, Song, Chun-Qing, Suresh, Sneha, Kwan, Suet-Yan, Wu, Qiongqiong, Walsh, Stephen, Ding, Junmei, Bogorad, Roman L, Zhu, Lihua Julie, Wolfe, Scot A et al. · 2018 · Nature Chemical Biology
  21. Combined CRISPRi/a-Based Chemical Genetic Screens Reveal that Rigosertib Is a Microtubule-Destabilizing Agent
    Marco Jost, Yuwen Chen, Luke A. Gilbert, Max A. Horlbeck, Lenno Krenning, Grégory Menchon, Ankit Rai, Min Y. Cho, Jacob J. Stern, Andrea Enrico Prota et al. · 2017 · Molecular Cell
  22. Enabling genetic analysis of diverse bacteria with Mobile-CRISPRi
    Jason M. Peters, Byoung‐Mo Koo, Ramiro Patino, Gary E. Heussler, Cameron C. Hearne, Jiuxin Qu, Yuki F. Inclán, John S. Hawkins, Candy H. S. Lu, Melanie R. Silvis et al. · 2018 · Nature Microbiology
  23. Application of the CRISPR/Cas9-based gene editing technique in basic research, diagnosis, and therapy of cancer
    Huimin Zhang, Chunhong Qin, Changming An, Xiwang Zheng, Shuxin Wen, Wenjie Chen, Xianfang Liu, Zhenghua Lv, Ping–Chang Yang, Wei Xu et al. · 2021 · Molecular Cancer
  24. Genome Editing with mRNA Encoding ZFN, TALEN, and Cas9
    Hongxia Zhang, Ying Zhang, Hao Yin · 2019 · Molecular Therapy
  25. Cas9 versus Cas12a/Cpf1: Structure–function comparisons and implications for genome editing
    Swarts, Daan C., Jinek, Martin · 2018 · WIREs RNA
  26. Sumoylation on its 25th anniversary: mechanisms, pathology, and emerging concepts
    Arda B. Celen, Umut Şahin · 2020 · FEBS Journal
  27. Engineering human tumour-associated chromosomal translocations with the RNA-guided CRISPR–Cas9 system
    Raúl Torres-Ruiz, Marina Carrasco Martin, Angie Fernanda Rodriguez Garcia, Juan C. Cigudosa, Juan Carlos Ramı́rez, Sandra Rodríguez · 2014 · Nature Communications
  28. Repurposing endogenous type I CRISPR-Cas systems for programmable gene repression
    Michelle L. Luo, Adam S. Mullis, Ryan T. Leenay, Chase L. Beisel · 2014 · Nucleic Acids Research
  29. High-throughput mapping of regulatory DNA
    Rajagopal, Nisha, Srinivasan, Sharanya, Kooshesh, Kameron, Guo, Yuchun, Edwards, Matthew D, Banerjee, Budhaditya, Syed, Tahin, Emons, Bart J M, Gifford, David K, Sherwood, Richard I · 2016 · Nature Biotechnology
  30. dCas9-based epigenome editing suggests acquisition of histone methylation is not sufficient for target gene repression
    Henriette O’Geen, Chonghua Ren, Charles M. Nicolet, Andrew A. Perez, Julian A. N. M. Halmai, Victoria M. Le, Joel P. Mackay, Peggy Farnham, David Jay Segal · 2017 · Nucleic Acids Research
  31. CRISPR Mediated Biosensing Toward Understanding Cellular Biology and Point‐of‐Care Diagnosis
    Yifan Dai, Yanfang Wu, Guozhen Liu, J. Justin Gooding · 2020 · Angewandte Chemie International Edition
  32. Engineered CAR-Macrophages as Adoptive Immunotherapies for Solid Tumors
    D. Christopher Sloas, Saar I. Gill, Michael Klichinsky · 2021 · Frontiers in Immunology
  33. Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM
    Alan S.L. Wong, Gigi C.G. Choi, Cheryl H. Cui, Gabriela Pregernig, Pamela Milani, Miriam Adam, Samuel David Perli, Samuel W. Kazer, Aleth Gaillard, Mario Hermann et al. · 2016 · Proceedings of the National Academy of Sciences
  34. Robust Transcriptional Activation in Plants Using Multiplexed CRISPR-Act2.0 and mTALE-Act Systems
    Lowder, Levi G., Zhou, Jianping, Zhang, Yingxiao, Malzahn, Aimee, Zhong, Zhaohui, Hsieh, Tzung-Fu, Voytas, Daniel F., Zhang, Yong, Qi, Yiping · 2018 · Molecular Plant
  35. A transcriptional switch governs fibroblast activation in heart disease
    Alexanian, Michael, Przytycki, Pawel F., Micheletti, Rudi, Padmanabhan, Arun, Ye, Lin, Travers, Joshua G., Gonzalez-Teran, Barbara, Silva, Ana Catarina, Duan, Qiming, Ranade, Sanjeev S. et al. · 2021 · Nature
  36. The ZSWIM8 ubiquitin ligase mediates target-directed microRNA degradation
    Charlie Y. Shi, Elena R. Kingston, Benjamin Kleaveland, Daniel H. Lin, Michael W. Stubna, David P. Bartel · 2020 · Science
  37. Targeted mRNA demethylation using an engineered dCas13b-ALKBH5 fusion protein
    Jiexin Li, Zhuojia Chen, Feng Chen, Guoyou Xie, Yu‐Yi Ling, Yanxi Peng, Lin Yu, Nan Luo, Cheng‐Ming Chiang, Hongsheng Wang · 2020 · Nucleic Acids Research
  38. Digital logic circuits in yeast with CRISPR-dCas9 NOR gates
    Miles W. Gander, Justin D. Vrana, William E. Voje, James M. Carothers, Eric Klavins · 2017 · Nature Communications
  39. Exploiting endogenous CRISPR-Cas system for multiplex genome editing in Clostridium tyrobutyricum and engineer the strain for high-level butanol production
    Jie Zhang, Wenming Zong, Wei Hong, Zhong-Tian Zhang, Yi Wang · 2018 · Metabolic Engineering
  40. Synergistic effects of common schizophrenia risk variants
    Nadine Schrode, Seok‐Man Ho, Kazuhiko Yamamuro, Amanda L. Dobbyn, Laura M. Huckins, Marliette R. Matos, Esther Cheng, P. J. Michael Deans, Erin K. Flaherty, Natalie Barretto et al. · 2019 · Nature Genetics
  41. Regulation of lifespan by neural excitation and REST
    Joseph Zullo, Derek Drake, Liviu Aron, Patrick O’Hern, Sameer C. Dhamne, Noah Davidsohn, Chai‐An Mao, William H. Klein, Alexander Rotenberg, David Alan Bennett et al. · 2019 · Nature
  42. Engineering prokaryotic transcriptional activators as metabolite biosensors in yeast.
    Mette L Skjoedt, T. Snoek, K. R. Kildegaard, Dushica Arsovska, M. Eichenberger, T. Goedecke, Arun S. Rajkumar, Jie Zhang, M. Kristensen, B. Lehka et al. · 2016 · Nature Chemical Biology
  43. dCas9-Based Scn1a Gene Activation Restores Inhibitory Interneuron Excitability and Attenuates Seizures in Dravet Syndrome Mice
    Gaia Colasante, Gabriele Lignani, Simone Brusco, Claudia Di Berardino, Jenna C. Carpenter, Serena Gea Giannelli, Nicholas Valassina, Simone Bido, Raffaele Ricci, Valerio Castoldi et al. · 2019 · Molecular Therapy
  44. Nucleosome breathing and remodeling constrain CRISPR-Cas9 function
    Isaac, R Stefan, Jiang, Fuguo, Doudna, Jennifer A, Lim, Wendell A, Narlikar, Geeta J, Almeida, Ricardo · 2016 · eLife
  45. Methods and Applications of CRISPR-Mediated Base Editing in Eukaryotic Genomes
    Hess, Gaelen T., Tycko, Josh, Yao, David, Bassik, Michael C. · 2017 · Molecular Cell
  46. NAD metabolic dependency in cancer is shaped by gene amplification and enhancer remodelling
    Sudhir Chowdhry, Ciro Zanca, Utkrisht Rajkumar, Tomoyuki Koga, Yarui Diao, Ramya Raviram, Feng Liu, Kristen M. Turner, Huijun Yang, Elizabeth Brunk et al. · 2019 · Nature
  47. ABC Transporter-Mediated Multidrug-Resistant Cancer
    Haneen A. Amawi, Hong‐May Sim, Amit Kumar Tiwari, Suresh V. Ambudkar, Suneet Shukla · 2019 · Advances in experimental medicine and biology
  48. CRISPR–Cas9 screens in human cells and primary neurons identify modifiers of C9ORF72 dipeptide-repeat-protein toxicity
    Kramer, Nicholas J., Haney, Michael S., Morgens, David W., Jovičić, Ana, Couthouis, Julien, Li, Amy, Ousey, James, Ma, Rosanna, Bieri, Gregor, Tsui, C. Kimberly et al. · 2018 · Nature Genetics
  49. The New State of the Art: Cas9 for Gene Activation and Repression
    Marie F. La Russa, Lei S. Qi · 2015 · Molecular and Cellular Biology
  50. A CRISPR view of development
    Melissa M. Harrison, Brian Jenkins, Kate M. O’Connor-Giles, Jill Wildonger · 2014 · Genes & Development
  51. A genome-wide analysis of Cas9 binding specificity using ChIP-seq and targeted sequence capture
    O'Geen, Henriette, Henry, Isabelle M., Bhakta, Mital S., Meckler, Joshua F., Segal, David J. · 2015 · Nucleic Acids Research
  52. Data storage in DNA with fewer synthesis cycles using composite DNA letters.
    Anavy, Leon, Vaknin, Inbal, Atar, Orna, Amit, Roee, Yakhini, Zohar · 2019 · Nature Biotechnology
  53. Evaluating Enhancer Function and Transcription
    Andrew R. Field, Karen Adelman · 2020 · Annual Review of Biochemistry
  54. Rapid characterization of CRISPR-Cas9 protospacer adjacent motif sequence elements
    Tautvydas Karvelis, Giedrius Gasiūnas, Joshua K. Young, Greta Bigelyte, Arūnas Šilanskas, Mark Cigan, Virginijus Šikšnys · 2015 · Genome biology
  55. CRISPR‐Cas9 Genome Editing in Drosophila
    Scott J. Gratz, Clifford Dustin Rubinstein, Melissa M. Harrison, Jill Wildonger, Kate M. O’Connor-Giles · 2015 · Current Protocols in Molecular Biology
  56. The ER membrane protein complex interacts cotranslationally to enable biogenesis of multipass membrane proteins
    Matthew J. Shurtleff, Daniel N. Itzhak, Jeffrey A. Hussmann, Nicole T Schirle Oakdale, Elizabeth A. Boydston, Martin C. Jonikas, Jimena Weibezahn, Katerina D. Popova, Calvin H. Jan, Pavel G. Sinitcyn et al. · 2018 · eLife
  57. CRISPR base editors: genome editing without double-stranded breaks
    Ayman Eid, Sahar Abdulaziz Alshareef, Magdy M. Mahfouz · 2018 · Biochemical Journal
  58. Distinct mechanisms of microRNA sorting into cancer cell-derived extracellular vesicle subtypes
    Morayma M. Temoche-Diaz, Matthew J. Shurtleff, Ryan M. Nottingham, Jun Yao, Raj P. Fadadu, Alan M. Lambowitz, Randy W. Schekman · 2019 · eLife
  59. Tau Internalization is Regulated by 6-O Sulfation on Heparan Sulfate Proteoglycans (HSPGs)
    Rauch, Jennifer N., Chen, John J., Sorum, Alexander W., Miller, Gregory M., Sharf, Tal, See, Stephanie K., Hsieh-Wilson, Linda C., Kampmann, Martin, Kosik, Kenneth S. · 2018 · Scientific Reports
  60. Genetic engineering of microalgae for enhanced biorefinery capabilities
    Fayyaz, Mehmooda, Chew, Kit Wayne, Show, Pau Loke, Ling, Tau Chuan, Ng, I-Son, Chang, Jo-Shu · 2020 · Biotechnology Advances
  61. Synthetic CRISPR-Cas gene activators for transcriptional reprogramming in bacteria
    Chen Dong, Jason T. Fontana, Anika Patel, James M. Carothers, Jesse G. Zalatan · 2018 · Nature Communications
  62. Potential of Genome Editing to Improve Aquaculture Breeding and Production
    Remi L. Gratacap, Anna Wargelius, Rolf B. Edvardsen, Ross D. Houston · 2019 · Trends in Genetics
  63. Application of CRISPR/Cas9 in plant biology
    Xuan Liu, Surui Wu, Jiao Xu, Chun Sui, Jianhe Wei · 2017 · Acta Pharmaceutica Sinica B
  64. Targeted Epigenetic Remodeling of Endogenous Loci by CRISPR/Cas9-Based Transcriptional Activators Directly Converts Fibroblasts to Neuronal Cells
    Joshua B. Black, Andrew F. Adler, Hong‐Gang Wang, Anthony M. D’Ippolito, Hunter Hutchinson, Timothy E. Reddy, Geoffrey S. Pitt, Kam W. Leong, Charles A. Gersbach · 2016 · Cell stem cell
  65. RNA-guided endonuclease provides a therapeutic strategy to cure latent herpesviridae infection
    Wang, Jianbin, Quake, Stephen R. · 2014 · Proceedings of the National Academy of Sciences
  66. Loss-of-function genetic tools for animal models: cross-species and cross-platform differences
    Benjamin E. Housden, Matthias Muhar, Matthew P. Gemberling, Charles A. Gersbach, Didier Y. R. Stainier, Géraldine Seydoux, Stephanie Elizabeth Mohr, Johannes A. Zuber, Norbert Perrimon · 2016 · Nature Reviews Genetics
  67. The Discovery, Mechanisms, and Evolutionary Impact of Anti-CRISPRs
    Adair L. Borges, Alan R. Davidson, Joseph Bondy‐Denomy · 2017 · Annual Review of Virology
  68. CRISPR/Cas9 advances engineering of microbial cell factories
    Tadas Jakočiūnas, Michael Krogh Jensen, Jay D. Keasling · 2015 · Metabolic Engineering
  69. Advances in Industrial Biotechnology Using CRISPR-Cas Systems
    Paul D. Donohoue, Rodolphe Barrangou, Andrew P. May · 2017 · Trends in biotechnology
  70. Hacking the Cancer Genome: Profiling Therapeutically Actionable Long Non-coding RNAs Using CRISPR-Cas9 Screening
    Roberta Esposito, Núria Bosch, Andrés Lanzós, Taisia Polidori, Carlos Pulido-Quetglas, Rory Johnson · 2019 · Cancer Cell
  71. Aptazyme-embedded guide RNAs enable ligand-responsive genome editing and transcriptional activation
    Weixin Tang, Johnny H. Hu, David R. Liu · 2017 · Nature Communications
  72. Enabling plant synthetic biology through genome engineering
    Nicholas J. Baltes, Daniel F. Voytas · 2014 · Trends in biotechnology
  73. CRISPR-Mediated Programmable 3D Genome Positioning and Nuclear Organization
    Haifeng Wang, Xiaoshu Xu, Cindy M. Nguyen, Yanxia Liu, Yuchen Gao, Xueqiu Lin, Timothy Daley, Nathan H. Kipniss, Marie F. La Russa, Lei S. Qi · 2018 · Cell
  74. Efficient C•G-to-G•C base editors developed using CRISPRi screens, target-library analysis, and machine learning
    Luke W. Koblan, Mandana Arbab, Max W. Shen, Jeffrey A. Hussmann, Andrew V. Anzalone, Jordan L. Doman, Gregory A. Newby, Dian Yang, Beverly Y. Mok, Joseph M. Replogle et al. · 2021 · Nature Biotechnology
  75. Application of CRISPR-Cas9 genome editing technology in various fields: A review
    Arif Nur Muhammad Ansori, Yulanda Antonius, Raden Joko Kuncoroningrat Susilo, Suhailah Hayaza, Viol Dhea Kharisma, Arli Aditya Parikesit, Rahadian Zainul, Vikash Jakhmola, Taru Saklani, Максим Борисович Ребезов et al. · 2023 · Narra J
  76. Epigenetics and the regulation of stress vulnerability and resilience
    Zannas, A.S., West, A.E. · 2014 · Neuroscience
  77. CRISPR/Cas9 and Genome Editing in Drosophila
    Andrew Roger Bassett, Ji‐Long Liu · 2013 · Journal of genetics and genomics/Journal of Genetics and Genomics
  78. Heterochromatin anomalies and double-stranded RNA accumulation underlie C9orf72 poly(PR) toxicity
    Yong‐Jie Zhang, Lin E. Guo, Patrick K. Gonzales, Tania F. Gendron, Yanwei Wu, Karen R. Jansen‐West, Aliesha D. O’Raw, Sarah R. Pickles, Mercedes Prudencio, Yari Carlomagno et al. · 2019 · Science
  79. Delivery of CRISPR/Cas systems for cancer gene therapy and immunotherapy
    Xiangrong Song, Chao Liu, Ning Wang, Hai Huang, Siyan He, Changyang Gong, Yuquan Wei · 2020 · Advanced Drug Delivery Reviews
  80. CRISPR-ERA: a comprehensive design tool for CRISPR-mediated gene editing, repression and activation: Fig. 1.
    Honglei Liu, Wei Zheng, Antonia A. Dominguez, Yanda Li, Xiaowo Wang, Lei S. Qi · 2015 · Computer applications in the biosciences
  81. Widespread Inducible Transcription Downstream of Human Genes
    Vilborg, Anna, Passarelli, Maria C., Yario, Therese A., Tycowski, Kazimierz T., Steitz, Joan A. · 2015 · Molecular Cell
  82. Assessing sufficiency and necessity of enhancer activities for gene expression and the mechanisms of transcription activation
    Rui R. Catarino, Alexander Stark · 2018 · Genes & Development
  83. CRISPR Activation Screens Systematically Identify Factors that Drive Neuronal Fate and Reprogramming
    Yanxia Liu, Yu Chen, Timothy Daley, Fangyuan Wang, William Cao, Salil S. Bhate, Xueqiu Lin, Chris Still, Honglei Liu, Dehua Zhao et al. · 2018 · Cell stem cell
  84. Recent advances in systems and synthetic biology approaches for developing novel cell-factories in non-conventional yeasts
    Pradipta Patra, Manali Das, Pritam Kundu, Amit Ghosh · 2021 · Biotechnology Advances
  85. CRISPR-Cas: New Tools for Genetic Manipulations from Bacterial Immunity Systems
    Wenyan Jiang, Luciano A. Marraffini · 2015 · Annual Review of Microbiology
  86. Downregulation of SNCA Expression by Targeted Editing of DNA Methylation: A Potential Strategy for Precision Therapy in PD
    Boris Kantor, Lidia Tagliafierro, Jeffrey T. Gu, Madison E. Zamora, Ekaterina Ilich, Carole Grenier, Zhiqing Y. Huang, Susan K. Murphy, Ornit Chiba‐Falek · 2018 · Molecular Therapy
  87. Simple and Rapid In Vivo Generation of Chromosomal Rearrangements using CRISPR/Cas9 Technology
    Rafael B. Blasco, Elif Karaca, Chiara Ambrogio, Taek-Chin Cheong, Emre Karayol, Valerio Giacomo Minero, Claudia Voena, Roberto Chiarle · 2014 · Cell Reports
  88. Challenges of CRISPR/Cas9 applications for long non-coding RNA genes
    Ashish Goyal, Ksenia Myacheva, Matthias Groß, Marcel Klingenberg, Berta Duran Arqué, Sven Diederichs · 2016 · Nucleic Acids Research
  89. Automated multiplex genome-scale engineering in yeast
    Tong Si, Ran Chao, Yuhao Min, Yuying Wu, Wen Ren, Huimin Zhao · 2017 · Nature Communications
  90. Recent advances in the CRISPR genome editing tool set
    Su Bin Moon, Do Yon Kim, Jeong‐Heon Ko, Yong-Sam Kim · 2019 · Experimental & Molecular Medicine
  91. Structural Plasticity of PAM Recognition by Engineered Variants of the RNA-Guided Endonuclease Cas9
    Anders, Carolin, Bargsten, Katja, Jinek, Martin · 2016 · Molecular Cell
  92. Cholesterol Pathway Inhibition Induces TGF-β Signaling to Promote Basal Differentiation in Pancreatic Cancer
    Linara Gabitova-Cornell, Aizhan Surumbayeva, Suraj Peri, Janusz Franco‐Barraza, Diana Restifo, Nicole Weitz, Charline Ogier, Aaron R. Goldman, Tiffiney R. Hartman, Ralph Francescone et al. · 2020 · Cancer Cell
  93. Profiling of engineering hotspots identifies an allosteric CRISPR-Cas9 switch
    Benjamin L. Oakes, Dana C Nadler, Avi I. Flamholz, Christof Fellmann, Brett T. Staahl, J. Doudna, D. Savage · 2016 · Nature Biotechnology
  94. Genome-wide CRISPR Screens in T Helper Cells Reveal Pervasive Crosstalk between Activation and Differentiation
    Johan Henriksson, Xi Xian Chen, Tomás Gomes, Ubaid Ullah, Kerstin B. Meyer, Ricardo J. Miragaia, Graham Duddy, Jhuma Pramanik, Kosuke Yusa, Riitta Lahesmaa et al. · 2019 · Cell
  95. Sequence features associated with the cleavage efficiency of CRISPR/Cas9 system
    Xiaoxi Liu, Ayaka Homma, Jamasb Joshua Sayadi, Shu Yang, Jun Ohashi, Toru Takumi · 2016 · Scientific Reports
  96. Compromised function of the ESCRT pathway promotes endolysosomal escape of tau seeds and propagation of tau aggregation
    Chen, John J., Nathaniel, Diane L., Raghavan, Preethi, Nelson, Maxine, Tian, Ruilin, Tse, Eric, Hong, Jason Y., See, Stephanie K., Mok, Sue-Ann, Hein, Marco Y. et al. · 2019 · Journal of Biological Chemistry
  97. Multiplex gene regulation by CRISPR-ddCpf1
    Xiaochun Zhang, Jingman Wang, Qiuxiang Cheng, Xuan Zheng, Guoping Zhao, Jin Wang · 2017 · Cell Discovery
  98. Efficient oligo nucleotide mediated CRISPR-Cas9 gene editing in Aspergilli
    Christina Spuur Nødvig, Jakob Blæsbjerg Nielsen, Martin E. Kogle, Zofia Dorota Jarczynska, Jan T. Lehmbeck, Dorte K. Klitgaard, Uffe Hasbro Mortensen · 2018 · Fungal Genetics and Biology
  99. CRISPR-Cas9: a new and promising player in gene therapy
    Xiao-Jie, Lu, Hui-Ying, Xue, Zun-Ping, Ke, Jin-Lian, Chen, Li-Juan, Ji · 2015 · Journal of Medical Genetics
  100. Strategies for nonviral nanoparticle‐based delivery of CRISPR/Cas9 therapeutics
    Chen, Fengqian, Alphonse, Martin, Liu, Qi · 2020 · WIREs Nanomedicine and Nanobiotechnology