CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes

Gilbert, Luke A., Larson, Matthew H., Morsut, Leonardo, Liu, Zairan, Brar, Gloria A., Torres, Sandra E., Stern-Ginossar, Noam, Brandman, Onn +5 more·2013·Cell

DOI 10.1016/j.cell.2013.06.044

Cited by (1,013)

Items 401–500 of 1,013

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Phage-Encoded Anti-CRISPR Defenses
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CRISPR-Cas-mediated transcriptional modulation: The therapeutic promises of CRISPRa and CRISPRi
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Jinhuan Li, Jia Shou, Ya Guo, Yuanxiao Tang, Yonghu Wu, Zhilian Jia, Yanan Zhai, Zhifeng Chen, Quan Xu, Qiang Wu · 2015 · Journal of Molecular Cell Biology
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CRISPRi engineering E. coli for morphology diversification
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CRISPRi-based radiation modifier screen identifies long non-coding RNA therapeutic targets in glioma
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Tetsushi Yamagata, Matthieu Raveau, Kenta Kobayashi, Hiroyuki Miyamoto, Tetsuya Tatsukawa, Ikuo Ogiwara, Shigeyoshi Itohara, Takao K. Hensch, Kazuhiro Yamakawa · 2020 · Neurobiology of Disease
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Epigenetics and addiction
Hamilton, Peter J, Nestler, Eric J · 2019 · Current Opinion in Neurobiology
A curative combination cancer therapy achieves high fractional cell killing through low cross-resistance and drug additivity
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Enhancer reprogramming driven by high-order assemblies of transcription factors promotes phenotypic plasticity and breast cancer endocrine resistance
Mingjun Bi, Zhao Zhang, Yi‐Zhou Jiang, Pengya Xue, Hu Wang, Zhao Lai, Xiaoyong Fu, Carmine De Angelis, Yue Gong, Zhen Gao et al. · 2020 · Nature Cell Biology
In Vivo Transcriptional Activation Using CRISPR/Cas9 in Drosophila
Shuailiang Lin, Ben Ewen‐Campen, Xiaochun Ni, Benjamin E. Housden, Norbert Perrimon · 2015 · Genetics
RNA‐based medicine: from molecular mechanisms to therapy
Anke Sparmann, Jörg Vogel · 2023 · The EMBO Journal
Subpopulations of Projection Neurons in the Olfactory Bulb
Fumiaki Imamura, Ayako Ito, Brandon J. LaFever · 2020 · Frontiers in Neural Circuits
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Prabin Kumar Sharma, Manalisha Saharia, Richa Srivstava, Sanjeev Kumar, Lingaraj Sahoo · 2018 · Frontiers in Marine Science
Activating PTEN Tumor Suppressor Expression with the CRISPR/dCas9 System
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Potent and Targeted Activation of Latent HIV-1 Using the CRISPR/dCas9 Activator Complex
Sheena M. Saayman, Daniel C. Lazar, Tristan A. Scott, Jonathan Ross Hart, Mayumi M. Takahashi, John Burnett, Vicente Planelles, Kevin V. Morris, Marc S. Weinberg · 2015 · Molecular Therapy
The CRISPR/Cas revolution continues: From efficient gene editing for crop breeding to plant synthetic biology
Jochen Kumlehn, Janine Pietralla, Göetz Hensel, Michael Pacher, Holger Puchta · 2018 · Journal of Integrative Plant Biology
Specificity of RNAi, LNA and CRISPRi as loss-of-function methods in transcriptional analysis
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CRISPR/Cas-based genome engineering in natural product discovery
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Therapeutic approaches for Duchenne muscular dystrophy
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Impeding Transcription of Expanded Microsatellite Repeats by Deactivated Cas9
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Péter István Kulcsár, András Tálas, Krisztina Huszár, Zoltán Ligeti, Eszter Tóth, Nóra Weinhardt, Elfrieda Fodor, Ervin Welker · 2017 · Genome biology
Mismatch-CRISPRi Reveals the Co-varying Expression-Fitness Relationships of Essential Genes in Escherichia coli and Bacillus subtilis
John S. Hawkins, Melanie R. Silvis, Byoung‐Mo Koo, Jason M. Peters, Hendrik Osadnik, Marco Jost, Cameron C. Hearne, Jonathan S. Weissman, Horia Todor, Carol A. Gross · 2020 · Cell Systems
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Aleksandra Majchrzak‐Celińska, Anna Szoszkiewicz, Mikołaj Szoszkiewicz · 2021 · Genes
Recent Advances in Genome Editing Using CRISPR/Cas9
Yuduan Ding, Hong Li, Ling‐Ling Chen, Kabin Xie · 2016 · Frontiers in Plant Science
Multiplexed Gene Editing and Protein Overexpression Using a Tobacco mosaic virus Viral Vector
Will B. Cody, Herman B. Scholthof, Theodore Erik Mirkov · 2017 · PLANT PHYSIOLOGY
Editing the microbiome the CRISPR way
Gayetri Ramachandran, David Bikard · 2019 · Philosophical Transactions of the Royal Society B Biological Sciences
Engineered CRISPRa enables programmable eukaryote-like gene activation in bacteria
Yang Liu, Xinyi Wan, Baojun Wang · 2019 · Nature Communications
Versatile detection with CRISPR/Cas system from applications to challenges
Hui Wu, Xiaoyun Chen, Mengyao Zhang, Xiaofu Wang, Yanju Chen, Cheng Qian, Jian Feng Wu, Junfeng Xu · 2020 · TrAC Trends in Analytical Chemistry
Stabilization of Foxp3 expression by CRISPR-dCas9-based epigenome editing in mouse primary T cells
Masahiro Okada, Mitsuhiro Kanamori, Kazue Someya, Hiroko Nakatsukasa, Akihiko Yoshimura · 2017 · Epigenetics & Chromatin
Engineering Synthetic Gene Circuits in Living Cells with CRISPR Technology
Barbara Jusiak, Sara Cleto, Pablo Pérez‐Piñera, Timothy K. Lu · 2016 · Trends in biotechnology
Synthetic hormone-responsive transcription factors can monitor and re-program plant development
Arjun Khakhar, Alexander R. Leydon, Andrew C Lemmex, Eric Klavins, Jennifer L. Nemhauser · 2018 · eLife
CRISPR/Cas9 gene-editing: Research technologies, clinical applications and ethical considerations
Fani Memi, Aglaia Ntokou, Irinna Papangeli · 2018 · Seminars in Perinatology
CRISPR-Cas: Converting A Bacterial Defence Mechanism into A State-of-the-Art Genetic Manipulation Tool
Loureiro, Alexandre, da Silva, Gabriela Jorge · 2019 · Antibiotics
Dead Cas Systems: Types, Principles, and Applications
Sergey Brezgin, Anastasiya Kostyusheva, Dmitry S. Kostyushev, Vladimir Chulanov · 2019 · International Journal of Molecular Sciences
CRISPR/Cas9 systems: Delivery technologies and biomedical applications
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Genome-wide specificity of DNA binding, gene regulation, and chromatin remodeling by TALE- and CRISPR/Cas9-based transcriptional activators
Lauren R. Polstein, Pablo Pérez‐Piñera, D. Dewran Koçak, Christopher M. Vockley, Peggy J. Bledsoe, Lingyun Song, Alexias Safi, Gregory E. Crawford, Timothy E. Reddy, Charles A. Gersbach · 2015 · Genome Research
CRISPR/Cas9‐mediated genome editing: From basic research to translational medicine
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CRISPR/dCas-mediated transcriptional and epigenetic regulation in plants
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Cut Site Selection by the Two Nuclease Domains of the Cas9 RNA-guided Endonuclease
Hongfan Chen, Jihoon Choi, Scott Bailey · 2014 · Journal of Biological Chemistry
Characterization of noncoding regulatory DNA in the human genome
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Protospacer adjacent motif (PAM)-distal sequences engage CRISPR Cas9 DNA target cleavage
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