BET Bromodomains Mediate Transcriptional Pause Release in Heart Failure

Anand, Priti, Brown, Jonathan D., Lin, Charles Y., Qi, Jun, Zhang, Rongli, Artero, Pedro Calderon, Alaiti, M. Amer, Bullard, Jace, Alazem, Kareem, Margulies, Kenneth B., Cappola, Thomas P., Lemieux, Madeleine, Plutzky, Jorge, Bradner, James E., Haldar, Saptarsi M.·2013·Cell
DOI 10.1016/j.cell.2013.07.013

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  8. BindingDB Entry 50012675: 4-Acyl Pyrroles as Dual BET-BRD7/9 Bromodomain Inhibitors Address BETi Insensitive Human Cancer Cell Lines.
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  9. BindingDB Entry 50002118: Structure-Based Discovery of 4-(6-Methoxy-2-methyl-4-(quinolin-4-yl)-9H-pyrimido[4,5-b]indol-7-yl)-3,5-dimethylisoxazole (CD161) as a Potent and Orally Bioavailable BET Bromodomain Inhibitor.
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  10. BindingDB Entry 50008116: Discovery, structural insight, and bioactivities of BY27 as a selective inhibitor of the second bromodomains of BET proteins.
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  11. BindingDB Entry 50000746: Drug Discovery Targeting Bromodomain-Containing Protein 4.
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  12. BindingDB Entry 50006935: Synthesis and elaboration of N-methylpyrrolidone as an acetamide fragment substitute in bromodomain inhibition.
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  13. BindingDB Entry 50000043: BET Bromodomain Inhibitors with One-Step Synthesis Discovered from Virtual Screen.
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  14. BindingDB Entry 50018743: Novel strategies targeting bromodomain-containing protein 4 (BRD4) for cancer drug discovery.
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  15. BindingDB Entry 50009340: Discovery of 8-Methyl-pyrrolo[1,2-
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  16. BindingDB Entry 50000864: Discovery of novel [1,2,4]triazolo[4,3-a]quinoxaline aminophenyl derivatives as BET inhibitors for cancer treatment.
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