Haldar, Saptarsi M.

Ketogenic Diet Reduces Midlife Mortality and Improves Memory in Aging Mice

Newman, J. C., Covarrubias, A. J., Zhao, M., Yu, X., Gut, P., Ng, C.-P., Huang, Y., Haldar, S., & Verdin, E. (2017) · Cell Metabolism

Genetics, Aging, and Longevity in Model OrganismsDiet and metabolism studies

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BET Bromodomains Mediate Transcriptional Pause Release in Heart Failure

Anand, P., Brown, J. D., Lin, C. Y., Qi, J., Zhang, R., Artero, P. C., Alaiti, M. A., Bullard, J., Alazem, K., Margulies, K. B., et al. (2013) · Cell

Protein Degradation and InhibitorsGenomics and Chromatin Dynamics

Cited by 406

Circadian rhythms govern cardiac repolarization and arrhythmogenesis

Jeyaraj, D., Haldar, S. M., Wan, X., McCauley, M. D., Ripperger, J. A., Hu, K., Lu, Y., Eapen, B. L., Sharma, N., Ficker, E., et al. (2012) · Nature

Cardiac electrophysiology and arrhythmiasCircadian rhythm and melatonin

Cited by 343

Myocardial Gene Expression Signatures in Human Heart Failure With Preserved Ejection Fraction

Hahn, V. S., Knutsdottir, H., Luo, X., Bedi, K., Margulies, K. B., Haldar, S. M., Stolina, M., Yin, J., Khakoo, A. Y., Vaishnav, J., et al. (2021) · Circulation

Cardiovascular Function and Risk FactorsHeart Failure Treatment and Management

Cited by 291

BET bromodomain inhibition suppresses innate inflammatory and profibrotic transcriptional networks in heart failure

Duan, Q., McMahon, S., Anand, P., Shah, H., Thomas, S., Salunga, H. T., Huang, Y., Zhang, R., Sahadevan, A., Lemieux, M. E., et al. (2017) · Science Translational Medicine

Protein Degradation and InhibitorsCardiac Fibrosis and Remodeling

Cited by 262

Preclinical development and phase 1 trial of a novel siRNA targeting lipoprotein(a)

Koren, M. J., Moriarty, P. M., Baum, S. J., Neutel, J., Hernandez-Illas, M., Weintraub, H. S., Florio, M., Kassahun, H., Melquist, S., Varrieur, T., et al. (2022) · Nature Medicine

Lipoproteins and Cardiovascular HealthRNA Interference and Gene Delivery

Cited by 239

A transcriptional switch governs fibroblast activation in heart disease

Alexanian, M., Przytycki, P. F., Micheletti, R., Padmanabhan, A., Ye, L., Travers, J. G., Gonzalez-Teran, B., Silva, A. C., Duan, Q., Ranade, S. S., et al. (2021) · Nature

Cardiac Fibrosis and RemodelingCongenital heart defects research

Cited by 238

Dynamic Chromatin Targeting of BRD4 Stimulates Cardiac Fibroblast Activation

Stratton, M. S., Bagchi, R. A., Felisbino, M. B., Hirsch, R. A., Smith, H. E., Riching, A. S., Enyart, B. Y., Koch, K. A., Cavasin, M. A., Alexanian, M., et al. (2019) · Circulation Research

Cardiac Fibrosis and RemodelingCongenital heart defects research

Cited by 179

Klf15 orchestrates circadian nitrogen homeostasis

Jeyaraj, D., Scheer, F. A. J. L., Ripperger, J. A., Haldar, S. M., Lu, Y., Prosdocimo, D. A., Eapen, S. J., Eapen, B. L., Cui, Y., Mahabeleshwar, G. H., et al. (2012) · Cell Metabolism

Circadian rhythm and melatoninKruppel-like factors research

Cited by 154

Chromatin remodelling drives immune cell–fibroblast communication in heart failure

Alexanian, M., Padmanabhan, A., Nishino, T., Travers, J. G., Ye, L., Pelonero, A., Lee, C. Y., Sadagopan, N., Huang, Y., Auclair, K., et al. (2024) · Nature

Cardiac Fibrosis and RemodelingCongenital heart defects research

Cited by 140

BRD4 (Bromodomain-Containing Protein 4) Interacts with GATA4 (GATA Binding Protein 4) to Govern Mitochondrial Homeostasis in Adult Cardiomyocytes

Padmanabhan, A., Alexanian, M., Linares-Saldana, R., González-Terán, B., Andreoletti, G., Huang, Y., Connolly, A. J., Kim, W., Hsu, A., Duan, Q., et al. (2020) · Circulation

Protein Degradation and InhibitorsCongenital heart defects research

Cited by 60

BET bromodomain proteins regulate transcriptional reprogramming in genetic dilated cardiomyopathy

Antolic, A., Wakimoto, H., Jiao, Z., Gorham, J. M., DePalma, S. R., Lemieux, M. E., Conner, D. A., Lee, D. Y., Qi, J., Seidman, J. G., et al. (2020) · JCI Insight

Cardiac Fibrosis and RemodelingCardiomyopathy and Myosin Studies

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