Promoting Health and Longevity through Diet: From Model Organisms to Humans

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Items 801–900 of 1,001

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2. Antioxidant and Antiaging Properties of a Novel Synergistic Nutraceutical Complex: Readouts from an In Cellulo Study and an In Vivo Prospective, Randomized Trial
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3. Sexual dimorphism in the response to dietary restriction in mice: A systematic review of the literature
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4. Intermittent Fasting as an Anti-Aging Strategy
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5. Nutritional Programming of the Lifespan of Male Drosophila by Activating FOXO on Larval Low-Nutrient Diet
   Yue Gao, Xingyi Cheng, Yao Tian, Zhixiao Yuan, Xiaolan Fan, Deying Yang, Mingyao Yang · 2023 · Nutrients
6. Dietary restriction fails to extend lifespan of Drosophila model of Werner syndrome
   Eileen Sember, Ranga Chennakesavula, Breanna Beard, Mubaraq Opoola, Dae‐Sung Hwangbo · 2024 · G3 Genes Genomes Genetics
7. Life history trade-offs imposed by dragline use in two money spiders
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8. The curious case of dermal fibroblasts: cell identity loss may be a mechanism underlying cardiovascular aging
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9. Severe food restriction activates the central renin angiotensin system
   Aline M. A. de Souza, Andrea Linares, Robert Charles Speth, Glenda Viggiano Campos, Hong Ji, Deoclécio Alves Chianca, Kathryn L. Sandberg, Rodrigo Cunha Alvim de Menezes · 2020 · Physiological Reports
10. Preconditioning with Short-Term Dietary Restriction Attenuates Cardiac Oxidative Stress and Hypertrophy Induced by Chronic Pressure Overload
    Miyuki Kobara, Naseratun Nessa, Hiroe Toba, Tetsuo Nakata · 2021 · Nutrients
11. Revealing the antiaging effects of cereal- and food oil-derived active substances by a Caenorhabditis elegans model
    Danling Xu, Qinlu Lin, Wei Wu, Yixin Wu, Ying Liang · 2021 · Food & Function
12. Lifespan and Healthspan Extension by Nutraceuticals: An Overview
    Sergio Davinelli, Giovanni Scapagnini · 2019 · Springer eBooks
13. Public health research needs for molecular epidemiology and to emphasize homeostasis – could the omnipotent endopeptidase inhibitor α-2-macroglobulin be a meaningful biomarker?
    Frank Peter Schelp, Ratthaphol Kraiklang, Benja Muktabhant, Pornpimon Chupanit, Pattara Sanchaisuriya · 2019 · F1000Research
14. Calorie restriction breaks an epigenetic barrier to longevity
    Diego Molina‐Serrano, Antonis Kirmizis · 2017 · Cell Cycle
15. The hidden costs of dietary restriction: implications for its evolutionary and mechanistic origins
    Andrew W McCracken, Gracie Adams, Laura Hartshorne, Mirre J. P. Simons · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
16. The Effects of Bitter Melon (Mormordica charantia) on Lipid Profile: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials
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17. Aging Reduces Intestinal Stem Cell Activity in Killifish and Intermittent Fasting Reverses Intestinal Gene Expression Patterns
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18. Diet, nutrition, and healthy aging: Are miRNAs the link? A narrative review
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19. Concept and connotation of the geroprotective and anti-aging effects of metformin: From AMPK activation to SASP suppression
    Abdullah I. Aedh, Hayder M. Al‐kuraishy, Mustafa M Shokr, Mubarak Alruwaili, Gaber El‐Saber Batiha · 2026 · Molecular and Cellular Endocrinology
20. Aging in nonhuman primates
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21. The Influence of Non-Pharmacological and Pharmacological Interventions on the Course of Autosomal Dominant Polycystic Kidney Disease
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22. Systematic transcriptomics analysis of calorie restriction and rapamycin unveils their synergistic interaction in prolonging cellular lifespan
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23. Gene Expression, Epigenetics and Ageing
    Babukrishna Maniyadath, Namrata Shukla, Ullas Kolthur‐Seetharam · 2018 · Sub-cellular biochemistry/Subcellular biochemistry
24. Oxidative Stress, DNA Damage and Repair Pathways in Patients with Type 2 Diabetes Mellitus
    Jéssica Ellen Barbosa de Freitas Lima, Danilo J. Xavier, Elza Tiemi Sakamoto‐Hojo · 2019 · IntechOpen eBooks
25. Compositional variation between high and low prokaryotic diversity coral reef biotopes translates to different predicted metagenomic gene content
    Daniel F. R. Cleary, Ana R. M. Polónia, Yusheng M. Huang, Thomas Swierts · 2019 · Antonie van Leeuwenhoek
26. Effects of caloric restriction on retinal aging and neurodegeneration
    Annagrazia Adornetto, Luigi Antonio Morrone, Andrea Satriano, Maria Luisa Laganà, Ester Licastro, Carlo Nucci, Maria Tiziana Corasaniti, Paolo Tonin, Giacinto Bagetta, Rossella Russo · 2020 · Progress in brain research
27. The genetic predisposition to longevity acts through behavioral phenotypes in females
    Sandra Van der Auwera, Linda Garvert, Georg Fuellen, Matthias A. Nauck, Henry Völzke, Uwe Völker, Hans Jörgen Grabe · 2021 · European Neuropsychopharmacology
28. Corticosterone and Glucocorticoid Receptor in the Cortex of Rats during Aging—The Effects of Long-Term Food Restriction
    Vesna Tešić, Jelena Ciric, Irena Jovanović Macura, Nevena S. Zogovic, Desanka Milanović, Selma Kanazir, Milka Perović · 2021 · Nutrients
29. Fasting and cancer: from yeast to mammals
    Maira Di Tano, Valter Daniel Longo · 2022 · International review of cytology
30. Protein-rich diet decreases survival, but does not alter reproduction, in fertile ant workers
    Marina Choppin, Miriam Schall, Barbara Feldmeyer, Susanne Foitzik · 2023 · Frontiers in Ecology and Evolution
31. Intermittent protein restriction improves glucose homeostasis in Zucker diabetic fatty rats and single-cell sequencing reveals distinct changes in β cells
    Chenchen Li, Jing Fei Zhu, Siying Wei, Xiaoyi Ye, Lanzexin Yang, Zinan Wang, Yan Chen · 2023 · The Journal of Nutritional Biochemistry
32. New Possibilities for Evaluating the Development of Age-Related Pathologies Using the Dynamical Network Biomarkers Theory
    Kazutaka Akagi, Keiichi Koizumi, Makoto Kadowaki, Isao Kitajima, Shigeru Saito · 2023 · Cells
33. Diversity, plasticity and asynchrony of actuarial and reproductive senescence in the Collembola Folsomia candida (Willem, 1902)
    Tully T. · 2023 · Frontiers in Ecology and Evolution
34. Dietary restriction and hepatic cancer: Systematic review and meta-analysis of animal studies
    Dallyla Jennifer Morais de Sousa, Kynnara Gabriella Feitosa de Oliveira, Irislene Costa Pereira, Glauto Tuquarre Melo do Nascimento, Clênio Oliveira Barrense, Jorddam Almondes Martins, Beatriz de Mello Pereira Rêgo, Tiago Eugênio Oliveira da Silva, Felipe Cavalcanti Carneiro da Silva, Francisco Leonardo Torres‐Leal · 2024 · Critical Reviews in Oncology/Hematology
35. A Nutrigenomic View on the Premature-Aging Disease Fanconi Anemia
    Eunike Velleuer, Carsten Carlberg · 2024 · Nutrients
36. Chrononutrition – ‘The Clock Makes Good Food’
    Christian E. W. Steinberg · 2018 · Springer eBooks
37. Improving Health in Later Life: How a Life Course Approach Could Improve Health and Well-Being in Old Age
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38. Sustainable Fishing Families: Developing industry human capital through health, wellbeing, safety and resilience
    Tanya J. King, Kirsten Abernethy, Susan A. Brumby, Tracey Hatherell, Sue Kilpatrick, Katarina Munksgaard, Rachel A. Turner · 2019 · eCite Digital Repository (University of Tasmania)
39. Aging and Age-Related Disorders: From Molecular Mechanisms to Therapies
    Vladimir I. Titorenko · 2019 · International Journal of Molecular Sciences
40. Intermittent fasting in athletes: PROs and CONs
    Valeria Laza · 2020 · Health Sports & Rehabilitation Medicine
41. Ways to become old: Role of lifestyle in modulation of the hallmarks of aging
    Giulia Accardi, Anna Aiello · 2021 · Elsevier eBooks
42. Cysteine Restriction in Murine L929 Fibroblasts as an Alternative Strategy to Methionine Restriction in Cancer Therapy
    Werner Schmitz, Elena Ries, Corinna Koderer, Maximilian Friedrich Völter, Anna Chiara Wünsch, Mohamed El‐Mesery, Kyra Frackmann, Alexander Christian Kübler, Christian Linz, Axel Seher · 2021 · International Journal of Molecular Sciences
43. New Roles for MicroRNAs in Old Worms
    Corrina R. Elder, Amy E. Pasquinelli · 2022 · Frontiers in Aging
44. A moderate static magnetic field promotes C. elegans longevity through cytochrome P450s
    Mengjiao Song, Shiming Dong, Xiang-Fei Zhang, Yumin Dai, Xin Zhang, Yidong Shen · 2022 · Scientific Reports
45. Azot expression in the Drosophila gut modulates organismal lifespan
    Marisa M. Merino · 2022 · Communicative & Integrative Biology
46. Natural Products in the Promotion of Healthspan and Longevity.
    Mireia Niso‐Santano, Rosa A. González‐Polo, Marta Paredes-Barquero, José Manuel Fuentes, Michael Aschner · 2019 · PubMed
47. Age-dependent effects of reduced mTor signalling on life expectancy through distinct physiology
    Mirre J. P. Simons, Laura Hartshorne, Suzan Trooster, Jessica Thomson, Marc Tatar · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
48. Resistance and Resilience to Alzheimer's Disease
    Caitlin S. Latimer, Katherine E. Prater, Nadia O. Postupna, Christopher Dirk Keene · 2023 · Cold Spring Harbor Perspectives in Medicine
49. Food touch limits lifespan through bioamine and neuroendocrine signaling
    Elizabeth S. Kitto, Safa Beydoun, Scott F. Leiser · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
50. Intense Caloric Restriction from Birth Protects the Heart Against Ischemia/Reperfusion Injury and Reduces Reactive Oxygen Species in Ovariectomized Rats
    Vinícius Lopes Cantuária, Cíntia Maria Rodrigues, Isabella Rocha Dias, Vinícius de Oliveira Ottone, Bruna Oliveira Costa, Lourdes Fernanda Godinho, Gabriela Silva, Marco Antônio Alves Schetino, Etel Rocha‐Vieira, Marco Fabrício Dias‐Peixoto et al. · 2025 · Antioxidants
51. Metabolic regulation of behavior by the intestinal enzyme FMO-2
    Elizabeth S. Kitto, Safa Beydoun, Ella Henry, Megan L. Schaller, Mira Bhandari, Sarah A. Easow, Angela M. Tuckowski, Marshall B. Howington, Ajay Bhat, Aditya Sridhar et al. · 2025 · Science Advances
52. Dietary Protein Restriction Ameliorates Cardiac Inflammaging via AMPK ‐ ULK1 ‐Mediated Mitochondrial Quality Control
    Wagner S. Dantas, Elizabeth R. M. Zunica, Elizabeth C. Heintz, Charles L. Hoppel, Cristal M. Hill, Christopher D. Morrison, Christopher L. Axelrod, Gangarao Davuluri, John P. Kirwan · 2026 · Aging Cell
53. Intermittent fasting: a comprehensive review of cellular mechanisms, metabolic processes, and organ health
    Jamil Adnan Samkari · 2025 · Journal of Umm Al-Qura University for Medical Sciences
54. Diet-induced metabolic and faecal microbiome responses in pet dogs fed a minimally processed versus extruded kibble diet
    L. C. CAMPBELL, Mary Thompson, Matthew Muir, David Raubenheimer, Andrew J. Holmes · 2026 · Frontiers in Veterinary Science
55. Calorie restriction and rapamycin distinctly restore non-canonical ORF translation in the muscles of aging mice
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56. Caloric Restriction Preserves BBB Integrity After Transient Focal Cerebral Ischemia Through Reducing Neutrophil Infiltration
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57. Immunomodulatory effects of calorie restriction and its mimetics: A new potential therapeutic approach for autoimmune diseases
    Monokesh Kumer Sen, Eileen Liao, Duan Ni, Anjie Ge, Laura M. Piccio · 2025 · Pharmacological Reviews
58. Stem Cell Aging and Rejuvenation in the Skeletal Muscle System
    Michela Libergoli, Albert E. Almada · 2025 · Rejuvenation Research
59. Nutritional associations with decelerated epigenetic aging: vegan diet in a Dutch population
    Georges E. Janssens, Jenny van Dongen, Lannie Ligthart, Eco J. C. de Geus, Gajja Sophi Salomons · 2025 · Clinical Epigenetics
60. A Pilot Study on the Urine Proteome of Cats Fed a High-Protein Complete Diet, Supplemented with or without Arginine, Ornithine or Zeolite
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61. Intermittent fasting shifts the diurnal transcriptome atlas of transcription factors
    Min Fu, Siyu Lu, Lijun Gong, Yiming Zhou, Fang Wei, Zhigui Duan, Rong Xiang, Frank J. Gonzalez, Guolin Li · 2024 · Molecular and Cellular Biochemistry
62. MONITTR allows real-time imaging of transcription and endogenous proteins in C. elegans
    Xiaofan Liu, Zhi Chang, Pingping Sun, Beibei Cao, Yuzhi Wang, Jie Fang, Yechun Pei, Baohui Chen, Wei Zou · 2024 · The Journal of Cell Biology
63. L’autophagie, l’homéostasie intestinale et ses pathologies
    Coralie Trentesaux, Marie Fraudeau, Béatrice Romagnolo · 2017 · médecine/sciences
64. Metabolic Aspects of Aging
    Yih-Woei C. Fridell, Felipe Sierra · 2018 · Progress in molecular biology and translational science
65. Effects of timing of food intake and fat/carbohydrate ratio on insulin sensitivity and preconditioning against renal ischemia reperfusion injury by calorie restriction
    Justin S. Reynolds, Wei Peng, Timothy Chu, James R. Mitchell · 2018 · Nutrition and Healthy Aging
66. Children’s understanding of food and activities on body size
    Lakshmi Raman, Kristan A. Marchak, Susan A. Gelman · 2020 · Cognitive Development
67. Fasting increases investment in soma upon refeeding at the cost of gamete quality in zebrafish
    Edward R. Ivimey‐Cook, David S. Murray, Jean‐Charles de Coriolis, Nathan Edden, Simone Immler, Alexei A. Maklakov · 2023 · Proceedings of the Royal Society B Biological Sciences
68. Activation of brown adipose tissue by a low-protein diet ameliorates hyperglycemia in a diabetic lipodystrophy mouse model
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69. ecl family genes: Factors linking starvation and lifespan extension in Schizosaccharomyces pombe
    Hokuto Ohtsuka, Yoko Otsubo, Takafumi Shimasaki, Akira Yamashita, Hirofumi Aiba · 2023 · Molecular Microbiology
70. Changes in micronutrient intake and factors associated with this change among older Australian men: the Concord Health and Ageing in Men Project
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71. Effects of caloric and time restriction diets on kidney health in rat model of postmenopausal acute kidney injury: An apoptosis and histopathological study.
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72. Investigating the Impact of a Curse: Diseases, Population Isolation, Evolution and the Mother’s Curse
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73. Fasting for stem cell rejuvenation
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74. Sexual identity of enterocytes regulates rapamycin-mediated intestinal homeostasis and lifespan extension
    Jennifer C. Regan, Yuxuan Lu, Enric Ureña, Ralf Leslie Meilenbrock, James H. Catterson, Disna Kißler, Linda Partridge · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
75. Nuclear receptor signaling via NHR-49/MDT-15 regulates stress resilience and proteostasis in response to reproductive and metabolic cues
    Ambre Julie Sala, Rogan A. Grant, Ghania Imran, Claire M. Morton, Renée M. Brielmann, Szymon Gorgoń, Jennifer L. Watts, Laura C. Bott, Richard I. Morimoto · 2024 · Genes & Development
76. Low protein-induced-FGF-21 signaling remodels adipose tissue on reduced markers of senescence during aging
    José A. Godoy-Lugo, Khristina E. Young, Prerana Vaddi, Yvann Batamack, Jolaiya Aldridge, Sun Ok Fernandez‐Kim, Diana C. Albarado, Susan J. Burke, Jacqueline M. Stephens, Christopher D. Morrison et al. · 2025 · GeroScience
77. Bacterial RNA promotes proteostasis through inter-tissue communication in C. elegans
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78. Deficiencies in methionine, tryptophan, and niacin remodels intestinal transcriptome and gut microbiota in female mice
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79. Angiogenesis-independent VEGF signaling enhances exercise capacity by increasing fat oxidation in mice fed sulfur amino acid-restricted diets
    Charlotte G. Mann, Michael Robert MacArthur, Jing Zhang, Songlin Gong, Jenna E. AbuSalim, Craig J. Hunter, Wenyun Lu, Thomas Agius, Alban Longchamp, Florent Allagnat et al. · 2025 · iScience
80. Diet quality and nutritional adequacy during a 2-year calorie restriction intervention: the Comprehensive Assessment of Long-Term Effects of Reducing Intake of Energy 2 trial
    Susan B. Racette, Rachel E. Silver, Valene Garr Barry, Jasmyn DeGraff, Jordan A. Gunning, Maryam Kebbe, Cheryl H. Gilhooly, Sai Krupa Das · 2025 · American Journal of Clinical Nutrition
81. Angel or demon? The dual role of branched-chain amino acids in chronic inflammatory and injury-related diseases
    Jiaxin Li, Hurong Chen, Ying Zhou, Liya Sun, Yao Xing, Yue Sun, Yufeng Yang, Yan Shi · 2026 · Frontiers in Immunology
82. Lsp2 links mTORC1 to TOP mRNA translation and lifespan in Drosophila
    Jun Wang, Zixin Cai, Jiaojiao Gu, Shiqi Xiong, Jianhan Yi, Meng Yang, Kexin Chang, Xinrui Ning, Yilin Wen, Yan Yan et al. · 2026 · Nature
83. Dietary Restriction in C. elegans
    Yue Zhang, William B. Mair · 2016 · Healthy ageing and longevity
84. Low-protein diet in cancer: ready for prime time?
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85. Methods to Determine Lysosomal AMPK Activation
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86. Consequences of senotherapies for tissue repair and reprogramming
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87. Synergetic effects between fasting, well-being and anti-consumption within the walls of Orthodox monasteries and outside them
    Teodora Kiryakova-Dineva, Ruska Krasteva, Yana Chankova · 2019 · British Food Journal
88. Molecular Biomarkers of Health
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89. Epithelial Cell Transformation and Senescence as Indicators of Genome Aging: Current Advances and Unanswered Questions
    Masatoshi Kitakaze, Ryota Chijimatsu, Andrea M. Vecchione, Toru Kitagawa, Yuichiro� Doki, Hidetoshi Eguchi, Hideshi Ishii · 2021 · International Journal of Molecular Sciences
90. Modestly Increased Incidence of Ketosis in Caloric Restriction Does not Significantly Alter the Effects of Caloric Restriction
    Bradley S. Ferguson, P. Sahoo, Erin McGrail, A. Francois, Matthew S. Stratton · 2022 · The journal of nutrition health & aging
91. Functional fiber enhances the effect of every-other-day fasting on insulin sensitivity by regulating the gut microecosystem
    Jianwei Gao, Chuanhui Xu, Mengdi Zhang, Jianhua Liu, Xiaoyu Wu, Chenbin Cui, Hongkui Wei, Jian Peng, Rong Zheng · 2022 · The Journal of Nutritional Biochemistry
92. Mitochondrial modulators
    Nataliia Naumova, Alexander K. Koliada, Nataliia Kuzub, Alexander M. Vaiserman · 2023 · Elsevier eBooks
93. Multigenerational mistimed feeding drives circadian reprogramming with an impaired unfolded protein response
    Kai Huang, Tao Zhang, Wenjun Zhang, Yue Gu, Yu Pan, Lanqing Sun, Zhiwei Liu, Tao Wang, Ying Xu · 2023 · Frontiers in Endocrinology
94. Does dietary nitrate boost the effects of caloric restriction on brain health? Potential physiological mechanisms and implications for future research
    Mushari Alharbi, Blossom C. M. Stephan, Oliver Michael Shannon, Mario Siervo · 2023 · Nutrition & Metabolism
95. Polr3b heterozygosity in mice induces both beneficial and deleterious effects on health during ageing with no effect on lifespan
    Gillian Borland, Stephen E. Wilkie, Jackie Thomson, Zhe Wang, Jennifer M. A. Tullet, Nazif Alic, Colin Selman · 2024 · Aging Cell
96. Maternal Brown Rice Diet during Pregnancy Promotes Adipose Tissue Browning in Offspring via Reprogramming PKA Signaling and DNA Methylation
    Lamei Xue, Juan Sun, Yujie Sun, Yu Wang, Kuiliang Zhang, Mingcong Fan, Haifeng Qian, Yan Li, Li Wang · 2024 · Molecular Nutrition & Food Research
97. Fueling the success of transplantation through nutrition: recent insights into nutritional interventions, their interplay with gut microbiota and cellular mechanisms
    Felix Carlo Koehler, Martin Richard Späth, Anna Maria Meyer, Roman‐Ulrich Müller · 2024 · Current Opinion in Organ Transplantation
98. Serum metabolomics reveals the anti-aging effect of royal jelly in D-galactose induced aging mice
    Han Hu, Guoda Lv, Qiaohong Wei, Xizi Liu, Fan Wu, Xuyuan Chao, Bin Han · 2024 · Journal of Functional Foods
99. Associations of dietary oxidative balance score with sarcopenia in adults: an NHANES-based cross-sectional study
    Qiang Zhou, Shang Zhou, Zuo-xi Chen, Wu-jie Zhou, Jia Su, Y. Claire Wang · 2025 · Nutrition & Metabolism
100. Findings from a UK–Morocco training programme to improve capacity in nutrition surveillance, research and education
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