The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Establishing Chromatin Regulatory Landscape during Mouse Preimplantation Development
Open accessAbstract
SUMMARY How the chromatin regulatory landscape in the inner cell mass cells is established from differentially packaged sperm and egg genomes during preimplantation development is unknown. Here we develop a low-input DNase I sequencing (liDNase-seq) method that allows us to generate maps of DNase I-hypersensitive site (DHS) of mouse preimplantation embryos from 1-cell to morula stage. The DHS landscape is progressively established with a drastic increase at the 8-cell stage. Paternal chromatin accessibility is quickly reprogrammed after fertilization to the level similar to maternal chromatin, while imprinted genes exhibit allelic accessibility bias. We demonstrate that transcription factor Nfya contributes to zygotic genome activation and DHS formation at the 2-cell stage and that Oct4 contributes to the DHSs gained at the 8-cell stage. Our study reveals the dynamic chromatin regulatory landscape during early development and identifies key transcription factors important for DHS establishment in mammalian embryos.
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Buenrostro, J. D., Giresi, P. G., Zaba, L. C., Chang, H. Y., & Greenleaf, W. J. (2013) · Nature Methods · doi:10.1038/nmeth.2688 · Cited by 6,422
The accessible chromatin landscape of the human genome
Thurman, R. E., Rynes, E., Humbert, R., Vierstra, J., Maurano, M. T., Haugen, E., Sheffield, N. C., Stergachis, A. B., Wang, H., Vernot, B., et al. (2012) · Nature · doi:10.1038/nature11232 · Cited by 2,679
Single-cell chromatin accessibility reveals principles of regulatory variation
Buenrostro, J. D., Wu, B., Litzenburger, U. M., Ruff, D., Gonzales, M. L., Snyder, M. P., Chang, H. Y., & Greenleaf, W. J. (2015) · Nature · doi:10.1038/nature14590 · Cited by 2,308
Multiplex single-cell profiling of chromatin accessibility by combinatorial cellular indexing
Cusanovich, D. A., Daza, R., Adey, A., Pliner, H. A., Christiansen, L., Gunderson, K. L., Steemers, F. J., Trapnell, C., & Shendure, J. (2015) · Science · doi:10.1126/science.aab1601 · Cited by 1,248
Genetic programs in human and mouse early embryos revealed by single-cell RNA sequencing
Xue, Z., Huang, K., Cai, C., Cai, L., Jiang, C.-Y., Feng, Y., Liu, Z., Zeng, Q., Cheng, L., Sun, Y. E., et al. (2013) · Nature · doi:10.1038/nature12364 · Cited by 963
The zinc-finger protein Zelda is a key activator of the early zygotic genome in Drosophila
Liang, H.-L., Nien, C.-Y., Liu, H.-Y., Metzstein, M. M., Kirov, N., & Rushlow, C. (2008) · Nature · doi:10.1038/nature07388 · Cited by 478
Genome-wide detection of DNase I hypersensitive sites in single cells and FFPE tissue samples
Jin, W., Tang, Q., Wan, M., Cui, K., Zhang, Y., Ren, G., Ni, B., Sklar, J., Przytycka, T. M., Childs, R., et al. (2015) · Nature · doi:10.1038/nature15740 · Cited by 332
Self-citation
Cited by
Mechanisms regulating zygotic genome activation
Schulz, K. N., & Harrison, M. M. (2019) · Nature Reviews Genetics · doi:10.1038/s41576-018-0087-x · Cited by 555
The maternal-to-zygotic transition revisited
Vastenhouw, N. L., Cao, W. X., & Lipshitz, H. D. (2019) · Development · doi:10.1242/dev.161471 · Cited by 445
Dynamics of the epigenetic landscape during the maternal-to-zygotic transition
Eckersley-Maslin, M. A., Alda-Catalinas, C., & Reik, W. (2018) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-018-0008-z · Cited by 431
Single-cell multi-omics sequencing of mouse early embryos and embryonic stem cells
Guo, F., Li, L., Li, J., Wu, X., Hu, B., Zhu, P., Wen, L., & Tang, F. (2017) · Cell Research · doi:10.1038/cr.2017.82 · Cited by 374
King, H. W., & Klose, R. J. (2017) · eLife · doi:10.7554/elife.22631 · Cited by 270
Metadata
- Authors
- Lu, F., Liu, Y., Inoue, A., Suzuki, T., Zhao, K., & Zhang, Y.
- Venue
- Cell
- Publisher
- Elsevier BV
- Published
- 2016-06
- Volume
- 165
- Issue
- 6
- Pages
- 1375-1388
- ISSN
- 0092-8674 (ISSN-L)
- OpenAlex
- W2409806253
- Cited by
- 340
- References
- 7
- FWCI
- 15.05
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Lu, F., Liu, Y., Inoue, A., Suzuki, T., Zhao, K., & Zhang, Y. (2016). Establishing Chromatin Regulatory Landscape during Mouse Preimplantation Development. Cell. https://doi.org/10.1016/j.cell.2016.05.050
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