Genome Organization Drives Chromosome Fragility

Cited by (383)

Items 201–300 of 383

  1. Disease-associated mutations in topoisomerase IIβ result in defective NK cells
    Lori Broderick, Gwendolyn M. Clay, Robert H. Blum, Yang Liu, Rachael N. McVicar, Fábio Papes, Laela M. Booshehri, Ian G. Cowell, Caroline A. Austin, Christopher D. Putnam et al. · 2022 · Journal of Allergy and Clinical Immunology
  2. Rearrangement of macronucleus chromosomes correspond to TAD-like structures of micronucleus chromosomes in Tetrahymena thermophila
    Zhengyu Luo, Tengfei Hu, Hong Jiang, Ruoyu Wang, Qianlan Xu, Simo V. Zhang, Jun Cao, Xiaoyuan Song · 2020 · Genome Research
  3. Broken by the Cut: A Journey into the Role of Topoisomerase II in DNA Fragility
    Naomi D. Atkin, Heather M. Raimer, Yuh‐Hwa Wang · 2019 · Genes
  4. Preserving genome integrity: The vital role of SUMO-targeted ubiquitin ligases
    Jinhua Han, Yanhua Mu, Jun Huang · 2023 · Cell Insight
  5. Rewiring cancer: 3D genome determinants of cancer hallmarks
    Maria Elisa Amodeo, Christine Elissa Eyler, Sarah E. Johnstone · 2025 · Current Opinion in Genetics & Development
  6. Perfecting DNA double-strand break repair on transcribed chromatin
    Xin Yi Tan, Michael S.Y. Huen · 2020 · Essays in Biochemistry
  7. Canonical non-homologous end-joining promotes genome mutagenesis and translocations induced by transcription-associated DNA topoisomerase 2 activity
    Joaquín Olmedo-Pelayo, Diana Rubio-Contreras, Fernando Gómez-Herreros · 2020 · Nucleic Acids Research
  8. Transcription-associated DNA breaks and cancer: A matter of DNA topology.
    Agnese Cristini, Mathéa Geraud, O. Sordet · 2021 · International Review of Cell and Molecular Biology
  9. Take a Break to Repair: A Dip in the World of Double-Strand Break Repair Mechanisms Pointing the Gaze on Archaea
    Mariarosaria De Falco, Mariarita De Felice · 2021 · International Journal of Molecular Sciences
  10. The human RNA polymerase I structure reveals an HMG-like docking domain specific to metazoans
    Julia L. Daiß, Michael Pilsl, Kristina Straub, Andrea Bleckmann, Mona Höcherl, Florian B. Heiss, Guillermo Abascal-Palacios, Ewan Phillip Ramsay, Katarína Tlučková, Jean-Clément Mars et al. · 2022 · Life Science Alliance
  11. DNA fragility at the KMT2A / MLL locus: insights from old and new technologies
    Ian G. Cowell, Caroline A. Austin · 2023 · Open Biology
  12. Modeling three-dimensional genomic organization in evolution and pathogenesis
    Alon Diament, Tamir Tuller · 2018 · Seminars in Cell and Developmental Biology
  13. Applications of advanced technologies for detecting genomic structural variation
    Vincent A. Laufer, Thomas W. Glover, Thomas E. Wilson · 2023 · Mutation Research/Reviews in Mutation Research
  14. Stratifying TAD boundaries pinpoints focal genomic regions of regulation, damage, and repair
    Bijia Chen, Chao Ren, Zhangyi Ouyang, Jingxuan Xu, Kang Xu, Yaru Li, Hejiang Guo, Xuemei Bai, Mengge Tian, Xiang Xu et al. · 2024 · Briefings in Bioinformatics
  15. Identification of Malignancy-Associated Changes in Histologically Normal Tumor-Adjacent Epithelium of Patients with HPV-Positive Oropharyngeal Cancer
    James Jabalee, Anita Carraro, Tony Ng, Eitan Prisman, Cathie Garnis, Martial D. Guillaud · 2018 · Analytical Cellular Pathology
  16. An evolutionary perspective of regulatory landscape dynamics in development and disease
    Martin Franke, José Luis Gómez-Skármeta · 2018 · Current Opinion in Cell Biology
  17. Chromatin Domains Go on Repeat in Disease
    Benoit G. Bruneau, Elphège Pierre Nora · 2018 · Cell
  18. DNA fragility at topologically associated domain boundaries is promoted by alternative DNA secondary structure and topoisomerase II activity
    Heather M. Raimer, Pei‐Chi Hou, Anna R. Bartosik, Naomi D. Atkin, Lixin Wang, Zhenjia Wang, Aakrosh Ratan, Chongzhi Zang, Yuh‐Hwa Wang · 2024 · Nucleic Acids Research
  19. Topoisomerase 2β and DNA topology during B cell development
    Olivier Papapietro, Sergey Nejentsev · 2022 · Frontiers in Immunology
  20. The Autonomous Parvovirus Minute Virus of Mice Localizes to Cellular Sites of DNA Damage Using ATR Signaling
    Clairine I. S. Larsen, Kinjal Majumder · 2023 · Viruses
  21. The impact of chromatin on double-strand break repair: Imaging tools and discoveries
    Marit Amber Elze van Bueren, Aniek Janssen · 2023 · DNA repair
  22. Intra-Vκ Cluster Recombination Shapes the Ig Kappa Locus Repertoire
    Kenta Shinoda, Yaakov Maman, Andrés Canela, David G. Schatz, Ferenc Livák, André Nussenzweig · 2019 · Cell Reports
  23. The Contribution of Pluripotent Stem Cell (PSC)-Based Models to the Study of Fragile X Syndrome (FXS)
    Manar Abu Diab, Rachel Eiges · 2019 · Brain Sciences
  24. Topoisomerases in Immune Cell Development and Function
    Prerana Muralidhara, Amit Kumar, Mukesh Kumar Chaurasia, Kushagra Bansal · 2023 · The Journal of Immunology
  25. Enhancers dysfunction in the 3D genome of cancer cells
    Giulia Della Chiara, Carlos Jiménez, Mohit Virdi, Nicola Crosetto, Magda Bienko · 2023 · Frontiers in Cell and Developmental Biology
  26. TOP2B Enzymatic Activity on Promoters and Introns Modulates Multiple Oncogenes in Human Gliomas
    Edgar González-Buendía, Junfei Zhao, Lu Wang, Subhas Mukherjee, Daniel Yang Zhang, Victor Andrés Arrieta, Eric Feldstein, JOSHUA ROBERT KANE, Seong Jae Kang, Catalina Lee-Chang et al. · 2021 · Clinical Cancer Research
  27. Secondary structure of the human mitochondrial genome affects formation of deletions
    Victor Shamanskiy, Alina A. Mikhailova, Evgenii O. Tretiakov, Kristina Ushakova, Alina G. Mikhailova, Sergey Oreshkov, Дмитрий Алексеевич Кнорре, Natalia Ree, Jonathan B. Overdevest, Samuel W. Lukowski et al. · 2023 · BMC Biology
  28. Keeping intracellular DNA untangled: A new role for condensin?
    Joaquim Roca, Sílvia Dyson, Joana Segura, Antonio Valdés, Belén Martínez-García · 2021 · Bioessays
  29. A Drosophila Insulator Interacting Protein Suppresses Enhancer-Blocking Function and Modulates Replication Timing
    Emily C. Stow, James Ryan Simmons, Ran An, Todd Andrew Schoborg, Nastasya M. Davenport, Mariano Labrador · 2019 · Gene
  30. Double-strand break repair and mis-repair in 3D
    Jennifer Zagelbaum, Jean Gautier · 2022 · DNA repair
  31. Toward understanding the dynamic state of 3D genome
    Soya Shinkai, Shuichi Onami, Ryuichiro Nakato · 2020 · Computational and Structural Biotechnology Journal
  32. Colibactin DNA damage signature indicates causative role in colorectal cancer
    Paulina J. Dziubańska-Kusibab, Hilmar Berger, Federica Battistini, Britta A. M. Bouwman, Amina Iftekhar, Riku Katainen, Nicola Crosetto, Modesto Orozco, Lauri A. Aaltonen, Thomas F. Meyer · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
  33. Genome-wide CRISPR off-target DNA break detection by the BLISS method
    Ballarino, Roberto, Bouwman, Britta A. M., Crosetto, Nicola · 2021 · Methods in molecular biology
  34. Causes and consequences of DNA double-stranded breaks in cardiovascular disease
    Ali J. Marian · 2024 · Molecular and Cellular Biochemistry
  35. 3D Genome Constrains Breakpoints of Inversions That Can Act as Barriers to Gene Flow in the Stickleback
    Yo Y. Yamasaki, Atsushi Toyoda, Mitsutaka Kadota, Shigehiro Kuraku, Jun Kitano · 2025 · Molecular Ecology
  36. Epigenetic priming promotes tyrosine kinase inhibitor resistance and oncogene amplification
    Rebecca M. Starble, Eric G. Sun, Rana Gbyli, Jonathan S. D. Radda, Jiuwei Lu, Tyler B Jensen, Ning Sun, Nelli Khudaverdyan, Ting Sheng Zhao, Bomiao Hu et al. · 2025 · Nature Structural & Molecular Biology
  37. DEtail-seq is an ultra-efficient and convenient method for meiotic DNA break profiling in multiple organisms
    Wei Min Xu, Chao Liu, Zhe Zhang, Changbin Sun, Qin Li, Kuan Li, Hui Jiang, Wei Li, Qianwen Sun · 2023 · Science China Life Sciences
  38. Genomes of the autonomous parvovirus minute virus of mice induce replication stress through RPA exhaustion
    MegAnn K. Haubold, Jessica N. Pita-Aquino, Sarah R. Rubin, Isabella K. Jones, Clairine I. S. Larsen, Edward Pham, Kinjal Majumder · 2023 · PLoS Pathogens
  39. Role of chromosomal architecture in germinal center B cells and lymphomagenesis
    Martín A. Rivas, Ari M. Melnick · 2019 · Current Opinion in Hematology
  40. Three-dimensional genome organization in normal and malignant haematopoiesis
    Sergi Cuartero, Matthias Merkenschlager · 2018 · Current Opinion in Hematology
  41. Encounters in Three Dimensions: How Nuclear Topology Shapes Genome Integrity
    Robin Sebastian, Mirit I. Aladjem, Philipp Oberdoerffer · 2021 · Frontiers in Genetics
  42. Chromosomal domain formation by archaeal SMC, a roadblock protein, and DNA structure
    2025
  43. High-throughput mapping of spontaneous mitotic crossover and genome instability events with sci-L3-Strand-seq
    Peter Chovanec, Trevor Ridgley, Yi Yin · 2026 · Nucleic Acids Research
  44. Evolutionary analysis of gene ages across TADs associates chromatin topology with whole-genome duplications
    Caelinn James, Marco Trevisán-Herraz, David Juan, Daniel Rico · 2024 · Cell Reports
  45. 3C methods in cancer research: recent advances and future prospects
    Insoo Yoon, Uijin Kim, Kyung Oh Jung, Yousuk Song, Taesoo Park, Dong-Sung Lee · 2024 · Experimental & Molecular Medicine
  46. Recurrent Germline Variant in RAD21 Predisposes Children to Lymphoblastic Leukemia or Lymphoma
    Anne Schedel, Ulrike Anne Friedrich, Mina N.F. Morcos, Rabea Wagener, Juha Mehtonen, Titus Watrin, Claudia Saitta, Triantafyllia Brozou, Pia Michler, Carolin Walter et al. · 2022 · International Journal of Molecular Sciences
  47. Single-cell diploid Hi-C reveals the role of spatial aggregations in complex rearrangements and KMT2A fusions in leukemia
    Zhihao Xing, Huirong Mai, Xiaorong Liu, Xiaoying Fu, Xingliang Zhang, Lichun Xie, Yunsheng Chen, Adam Shlien, Feiqiu Wen · 2022 · Genome biology
  48. The Contribution of Double-strand Break Repair Radiation Sensitive Protein 51 Genotypes to Lung Cancer in Taiwan
    Kuo-Liang Chiu, Shou-Cheng Wang, Chia-Hsiang Li, Te‐Chun Shen, LI-HSIOU CHEN, Yi‐Cheng Shen, WEN-SHIN CHANG, Chia-Wen Tsai, Te‐Chun Hsia, DA-TIAN BAU · 2024 · Anticancer Research
  49. Genetic, Environmental, and Nuclear Factors Governing Genomic Rearrangements
    Susmita Gurjar Ramanand, Ram Shankar Mani · 2019 · Advances in experimental medicine and biology
  50. Mutations in the insulator protein Suppressor of Hairy wing induce genome instability
    Shih-Jui Hsu, Emily C. Stow, James Ryan Simmons, Heather A. Wallace, Andrea A. Lopez, Shannon Stroud, Mariano Labrador · 2020 · Chromosoma
  51. Transcriptional Regulation of RUNX1: An Informatics Analysis
    Amarni Thomas, Judith Marsman, Jisha Antony, W. Schierding, J. O'Sullivan, Julia A. Horsfield · 2021 · Genes
  52. Osmotic disruption of chromatin induces Topoisomerase 2 activity at sites of transcriptional stress
    William H. Gittens, Rachal M. Allison, Ellie M. Wright, George G. B. Brown, Matthew J. Neale · 2024 · Nature Communications
  53. Small Genomes, Big Disruptions: Parvoviruses and the DNA Damage Response
    Rhiannon R. Abrahams, Kinjal Majumder · 2025 · Viruses
  54. Epigenomic signatures associated with spontaneous and replication stress-induced DNA double strand breaks
    Sravan Kodali, Silvia Meyer‐Nava, Stephen Landry, Arijita Chakraborty, Juan Carlos Rivera‐Mulia, Wenyi Feng · 2022 · Frontiers in Genetics
  55. Lessons from Using Genetically Engineered Mouse Models of MYC-Induced Lymphoma
    René Winkler, Eva-Maria Piskor, Christian Kosan · 2022 · Cells
  56. Chromatin dynamics and RNA metabolism are double-edged swords for the maintenance of plant genome integrity
    Clara Bergis, Meega Reji, David Latrasse, Catherine Bergounioux A, Moussa Benhamed, Cécile Raynaud · 2024 · Nature Plants
  57. Break Check: Transcription-Driven Topoisomerase II Collisions near Chromatin Loop Anchors Are Hotspots for DNA Damage and Translocations
    Liis Uusküla-Reimand, Michael D. Wilson · 2019 · Molecular Cell
  58. High Temperature Drives Topoisomerase Mediated Chromosomal Break Repair Pathway Choice
    Mohamed E. Ashour, Walaa Ramadan Allam, Waheba Elsayed, Reham Atteya, Menattallah Elserafy, Sameh Magdeldin, Mohamed Kamel Hassan, Sherif F. El‐Khamisy · 2021 · Cancers
  59. Topoisomerase IIβ targets DNA crossovers formed between distant homologous sites to induce chromatin opening
    Mary Miyaji, Ryohei Furuta, Osamu Hosoya, Kuniaki Sano, Norikazu Hara, Ryozo Kuwano, Jiyoung Kang, Masaru Tateno, Kimiko Tsutsui, Ken Tsutsui · 2020 · Scientific Reports
  60. Identification and characterization of eccDNA-driven genes in humans
    Yuxi Gu, Yidan Song, Jun Liu · 2025 · PLoS ONE
  61. Adeno-Associated Virus 2 (AAV2) - Induced RPA exhaustion generates cellular DNA damage and restricts viral gene expression
    Monnette F. Summers, MegAnn K. Haubold, Marcel Morgenstern, Phoenix M. Shepherd, Clairine I. S. Larsen, Ava E. Bartz, Gopishankar Thirumoorthy, Robert N. Kirchdoerfer, Joshua J. Coon, Kavi P.M. Mehta et al. · 2025 · PLoS Pathogens
  62. Topoisomerase IIb binding delineates localized mutational processes and driver mutations in cancer genomes
    Liis Uusküla-Reimand, Christian A. Lee, Robin H. Oh, Zoe P. Klein, Nina Adler, Sana Akhtar Alvi, Ellen Langille, Elisa Pasini, Kevin C. L. Cheng, Evgenija Serafimova et al. · 2025 · Nature Communications
  63. The centromere: the punching bag of the chromosome
    Annapaola Angrisani, Daniele Fachinetti · 2025 · Chromosome Research
  64. SRBD1 facilitates chromosome segregation by promoting topoisomerase IIα localization to mitotic chromosomes
    Courtney A. Lovejoy, Sarah R. Wessel, Rahul Bhowmick, Yuki Hatoyama, Masato T. Kanemaki, Runxiang Zhao, David Cortez · 2025 · Nature Communications
  65. The relationship between chimeric RNAs and gene fusions: Potential implications of reciprocity in cancer
    Justin Elfman, Lam-Phong Pham, Hui Li · 2020 · Journal of genetics and genomics/Journal of Genetics and Genomics
  66. Optimized methods for mapping DNA double-strand-break ends and resection tracts and application to meiotic recombination in mouse spermatocytes
    Soonjoung Kim, Shintaro Yamada, Kaku Maekawa, Scott Keeney · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  67. The MRE11-RAD50-NBS1 complex both starts and extends DNA end resection in mouse meiosis
    Soonjoung Kim, Shintaro Yamada, Tao Li, Claudia Canasto‐Chibuque, Jun Hyun Kim, Marina Marcet-Ortega, Jiaqi Xu, Diana Y. Eng, Laura Feeney, John H.J. Petrini et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  68. MDM2 provides TOP2 poison resistance by promoting proteolysis of TOP2βcc in a p53-independent manner
    Jianfeng Shu, Jinni Jiang, Xiaofang Wang, Xuejie Yang, Guofang Zhao, Ting Cai · 2024 · Cell Death and Disease
  69. Unfolding neural diversity: how dynamic three-dimensional genome architecture regulates brain function and disease
    Brandon L. Logeman, Steven F. Grieco, Todd C. Holmes, Xiangmin Xu · 2025 · Molecular Psychiatry
  70. DNA Damage Meets Neurotrophin Signaling: A Delicate Balancing AKT to Maintain Virus Latency
    Anna Ruth Cliffe · 2019 · Molecular Cell
  71. Assessing acute myeloid leukemia susceptibility in rearrangement‐driven patients by DNA breakage at topoisomerase II and CCCTC‐binding factor/cohesin binding sites
    Naomi D. Atkin, Heather M. Raimer, Zhenjia Wang, Chongzhi Zang, Yuh‐Hwa Wang · 2021 · Genes Chromosomes and Cancer
  72. Chromatin accessibility shapes meiotic recombination in mouse primordial germ cells through assisting double-strand breaks and loop formation
    Guoqing Liu, Yu Sun, Lumeng Jia, Ruifeng Li, Yongchun Zuo · 2022 · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
  73. The 3D genome landscape: Diverse chromosomal interactions and their functional implications
    Katherine Fleck, Romir Raj, Jelena Erceg · 2022 · Frontiers in Cell and Developmental Biology
  74. Innovative Tools for DNA Topology Probing in Human Cells Reveal a Build-Up of Positive Supercoils Following Replication Stress at Telomeres and at the FRA3B Fragile Site
    Claire Ghilain, Olivia Vidal-Cruchez, Aurélia Joly, Michelle Debatisse, Éric Gilson, Marie-Josèphe E. Giraud-Panis · 2024 · Cells
  75. The genomic false shuffle: epigenetic maintenance of topological domains in the rearranged gibbon genome
    Nathan H. Lazar, Kimberly A. Nevonen, Brendan L. O’Connell, Richard Edward Green, Thomas Joshua Meyer, Mariam Okhovat, Lucia Carbone · 2017 · bioRxiv (Cold Spring Harbor Laboratory)
  76. Mapping the breakome reveals tight regulation on oncogenic super-enhancers
    Sara K. Oster, Rami I. Aqeilan · 2020 · Molecular & Cellular Oncology
  77. Multi-contact 3C data reveal that the human genome is largely unentangled
    Filipe Tavares-Cadete, Davood Norouzi, Bastiaan Dekker, Yu Liu, Job Dekker · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  78. Identifying regulatory and spatial genomic architectural elements using cell type independent machine and deep learning models
    Laura D. Martens, Oisín Faust, Liviu Pirvan, Dóra Bihary, Shamith Samarajiwa · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  79. Association of hepatitis B virus genomes with active chromatin hubs challenges host replication fidelity, leading to DNA damage
    Gavin J. Marcoe, Clairine I. S. Larsen, Monnette F. Summers, Kinjal Majumder · 2025 · Journal of Virology
  80. LRRC59 cooperates with nuclear transporters to restrain the nuclear envelope repair machinery and safeguard genome integrity
    Romy Timmer, Aurélie Bellanger, Sarah Peeters, Hokyoung Kim, Laura Rodríguez de la Ballina, Sissel Eikvar, Annemijn J. Arns, Esmée Oortgijs, Nikolina Sekulić, Winnok Harald De Vos et al. · 2025 · Nature Communications
  81. Epigenetic aging and rejuvenation of the brain: drivers, consequences, and interventions
    Seunghyun Lee, SeungA Cho, Seung-Kyoon Kim, Jae-Hyun Yang · 2026 · BMB Reports
  82. ERCC6L2 ensures repair fidelity for staggered-end DNA double-strand breaks
    Eric J. Aird, Almudena Serrano-Benítez, Sebastian M. Siegner, Elda Cannavò, Rimma Belotserkovskaya, Nadia Gueorguieva, John Fielden, Grégoire Cullot, Sandra Ammann, Aldo S. Bader et al. · 2026 · Nature Communications
  83. Fibrillarin promotes homologous recombination repair by facilitating the recruitment of recombinase RAD51 to DNA damage sites
    Yanhua Mu, Jinhua Han, Mingjie Wu, Zongfang Li, Ke Du, Yameng Wei, Mengjie Wu, Jun Huang · 2023 · Journal of Zhejiang University SCIENCE B
  84. Local Genomic Instability of the SpTransformer Gene Family in the Purple Sea Urchin Inferred from BAC Insert Deletions
    Megan A. Barela Hudgell, F. Momtaz, Abiha Jafri, Max A. Alekseyev, L. Smith · 2024 · Genes
  85. The fork protection complex generates DNA topological stress–induced DNA damage while ensuring full and faithful genome duplication
    Andrea Keszthelyi, Sahar Mansoubi, Alex J. Whale, Jonathan M. Houseley, Jonathan Baxter · 2024 · Proceedings of the National Academy of Sciences
  86. Downstream transcription promotes human recurrent CNV associated AT-rich sequence mediated genome rearrangements in yeast
    Feng-Yun Xie, Xiao-Guohui Zhang, Juan Chen, Xin Xu, Sen Li, Tian-Jin Xia, Lei-Ning Chen, Shen Yin, Xiang‐Hong Ou, Jun‐Yu Ma · 2024 · iScience
  87. Adding a twist to the loops: the role of DNA superhelicity in the organization of chromosomes by SMC protein complexes
    Antonio Valdés, Christian H. Haering · 2024 · Biochemical Society Transactions
  88. Epstein-Barr Virus and host cell 3D genome organization
    Chong Wang, Bo Zhao · 2023 · Journal of Medical Virology
  89. Stromal Rigidity Stress Accelerates Pancreatic Intraepithelial Neoplasia Progression and Chromosomal Instability via Nuclear Protein Tyrosine Kinase 2 Localization
    Li-Yun Ding, Chih‐Han Chang, Szu-Ying Chen, Kuan-Lin Chen, Yueh-Shan Li, Y.R. Wu, Ting-Yi Hsu, Hsin-Yu Ying, Hsin‐Yi Wu, Michael Warren Hughes et al. · 2024 · American Journal Of Pathology
  90. Aclarubicin Reduces the Nuclear Mobility of Human DNA Topoisomerase IIβ
    Keiko Morotomi‐Yano, Ken-ichi Yano · 2024 · International Journal of Molecular Sciences
  91. Safeguarding genomic integrity in beta-cells: implications for beta-cell differentiation, growth, and dysfunction
    Sneha S. Varghese, Alessandro Giovanni Hernandez-De La Peña, Sangeeta Dhawan · 2024 · Biochemical Society Transactions
  92. One ring to rule them all
    Ferenc Livák, André Nussenzweig · 2019 · Nature
  93. Transcription of carbonyl reductase 1 is regulated by DNA topoisomerase II beta
    Mushtaq M. Khazeem, Ian G. Cowell, Lauren F. Harkin, John Casement, Caroline A. Austin · 2020 · FEBS Letters
  94. Breaking the paradigm: early insights from mammalian DNA breakomes
    Xanita Saayman, Fumiko Esashi · 2021 · FEBS Journal
  95. Coolpup.py – a versatile tool to perform pile-up analysis of Hi-C data
    Ilya M. Flyamer, Robert Scott Illingworth, Wendy A. Bickmore · 2019 · Figshare
  96. BLM-dependent Break-Induced Replication handles DSBs in transcribed chromatin upon impaired RNA:DNA hybrids dissolution
    S Cohen, Aude Guénolé, Aline Marnef, Thomas Clouaire, Nadine Puget, Vincent Rocher, Coline Arnould, Marion Aguirrebengoa, Matthieu Genais, Dipti Vinayak Vernekar et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  97. Dynamic and facilitated binding of topoisomerase accelerates topological relaxation.
    Davide Michieletto, Yair Augusto Gutiérrez Fosado, Elias Melas, Marco Baiesi, Luca Tubiana, Enzo Orlandini · 2022 · PubMed Central
  98. The Biological Function of Genome Organization
    Xin Yang, Hongni Zhu, Yajie Liu, Jinhong Wang, Yi Song, Shasha Liao, Peng Dong · 2025 · International Journal of Molecular Sciences
  99. Processing of DNA Topoisomerase II – DNA –Protein Crosslinks Associated With Anticancer Drugs
    Ryo Sakasai, Kuniyoshi Iwabuchi · 2025 · Genes to Cells
  100. CTCF/cohesin-binding sites are susceptible to replication-associated DNA damage and genomic instability in cancer cells
    Elangoli Ebrahimkutty Faseela, Dimple Notani, Radhakrishnan Sabarinathan · 2026 · iScience