The Dynamic Landscape of Open Chromatin during Human Cortical Neurogenesis
de la Torre-Ubieta, Luis, Stein, Jason L., Won, Hyejung, Opland, Carli K., Liang, Dan, Lu, Daning, Geschwind, Daniel H.·2018·Cell
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Items 101–200 of 354
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- Histone Variants and Histone Modifications in NeurogenesisMengtian Zhang, Jinyue Zhao, Yuqing Lv, Wenwen Wang, Chao Feng, Wenzheng Zou, Libo Su, Jianwei Jiao · 2020 · Trends in Cell Biology
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- 3D spatial genome organization in the nervous system: From development and plasticity to diseaseYuki Fujita, Sarshan R. Pather, Guo‐li Ming, Hongjun Song · 2022 · Neuron
- De novo human brain enhancers created by single-nucleotide mutationsShan Li, Sridhar S. Hannenhalli, Ivan Ovcharenko · 2023 · Science Advances
- Looking at neurodevelopment through a big data lensJames Briscoe, Óscar Marín · 2020 · Science
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- Evaluating brain structure traits as endophenotypes using polygenicity and discoverabilityNana Matoba, Michael I. Love, Jason L. Stein · 2020 · Human Brain Mapping
- The Evolutionary History of Common Genetic Variants Influencing Human Cortical Surface AreaAmanda K. Tilot, Ekaterina A. Khramtsova, Dan Liang, Katrina L. Grasby, Neda Jahanshad, Jodie N. Painter, Lucía Colodro‐Conde, Janita Bralten, Derrek P. Hibar, Penelope A. Lind et al. · 2020 · Cerebral Cortex
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- Lineage specific 3D genome structure in the adult human brain and neurodevelopmental changes in the chromatin interactomeSamir Rahman, Pengfei Dong, Pasha Apontes, Michael B. Fernando, Roman Kosoy, Kayla G. Townsley, Kiran Girdhar, Jaroslav M. Bendl, Zhiping Shao, Ruth Misir et al. · 2023 · Nucleic Acids Research
- Evolution of new miRNAs and cerebro-cortical developmentKosik, Kenneth S., Nowakowski, Tomasz · 2018 · Annual Review of Neuroscience
- Single cell epigenomic atlas of the developing human brain and organoidsZiffra, Ryan S., Kim, Chang N., Wilfert, Amy, Turner, Tychele N., Haeussler, Maximilian, Casella, Alex M., Przytycki, Pawel F., Kreimer, Anat, Pollard, Katherine S., Ament, Seth A. et al. · 2019
- Temporal analysis of enhancers during mouse cerebellar development reveals dynamic and novel regulatory functionsMiguel Ramirez, Yuliya Badayeva, Joanna Yeung, Joshua Wu, Ayasha Abdalla-Wyse, Erin Yang, Brett Trost, Stephen W. Scherer, Dan Goldowitz · 2022 · eLife
- Polygenic profiles define aspects of clinical heterogeneity in attention deficit hyperactivity disorderSonja LaBianca, Isabell Brikell, Dorte Helenius, Robert J. Loughnan, Joel Mefford, Clare E. Palmer, Rebecca L. Walker, Jesper R. Gådin, Morten Dybdahl Krebs, Vivek Appadurai et al. · 2023 · Nature Genetics
- PsychENCODE and beyond: transcriptomics and epigenomics of brain development and organoidsAlexandre Jourdon, Soraya Scuderi, Davide Capauto, Alexej S. Abyzov, Flora Maria Vaccarino · 2020 · Neuropsychopharmacology
- Variation of Human Neural Stem Cells Generating Organizer States In Vitro before Committing to Cortical Excitatory or Inhibitory Neuronal FatesMicali, Nicola, Kim, Suel-Kee, Diaz-Bustamante, Marcelo, Stein-O’Brien, Genevieve, Seo, Seungmae, Shin, Joo-Heon, Rash, Brian G., Ma, Shaojie, Wang, Yanhong, Olivares, Nicolas A. et al. · 2020 · Cell Reports
- Comparative chromatin accessibility upon BDNF stimulation delineates neuronal regulatory elementsIgnacio L. Ibarra, Vikram Singh Ratnu, Lucia Gordillo, In‐Young Hwang, Luca Mariani, Kathryn Weinand, Henrik M. Hammarén, Jennifer Heck, Martha L. Bulyk, Mikhail M. Savitski et al. · 2022 · Molecular Systems Biology
- Enhancer Dysfunction in 3D Genome and DiseaseJi‐Han Xia, Gong‐Hong Wei · 2019 · Cells
- Dynamic chromatin accessibility profiling reveals changes in host genome organization in response to baculovirus infectionXiangshuo Kong, Guisheng Wei, Nan Chen, Shudi Zhao, Yunwang Shen, Jianjia Zhang, Yang Li, Xiaoqun Zeng, Xiaofeng Wu · 2020 · PLoS Pathogens
- Comprehensive multi-omics integration identifies differentially active enhancers during human brain development with clinical relevanceSoheil Yousefi, Ruizhi Deng, Kristina Lanko, Eva Medico Salsench, Anita Nikoncuk, Herma C. van der Linde, Elena Perenthaler, Tjakko J. van Ham, Eskeatnaf Mulugeta, Tahsin Stefan Barakat · 2021 · Genome Medicine
- Heterogeneous fates of simultaneously-born neurons in the cortical ventricular zoneElia Magrinelli, Natalia Baumann, Robin Jan Wagener, Christelle Glangetas, Camilla Bellone, Denis Jabaudon, Esther Klingler · 2022 · Scientific Reports
- Neuroepigenetics of ageing and neurodegeneration-associated dementia: An updated reviewFayaz Ahmad Mir, Ayeman Amanullah, Buddhi Prakash Jain, Zeeshan Hyderi, Akash Gautam · 2023 · Ageing Research Reviews
- Development and evolution of the primate neocortex from a progenitor cell perspectiveColette Dehay, Wieland Β. Huttner · 2024 · Development
- Neuronal enhancers fine-tune adaptive circuit plasticityEric C. Griffith, Anne E. West, Michael E. Greenberg · 2024 · Neuron
- Consensus molecular environment of schizophrenia risk genes in coexpression networks shifting across age and brain regionsGiulio Pergola, Madhur Parihar, Leonardo Sportelli, Rahul A. Bharadwaj, Christopher Borcuk, Eugenia Radulescu, Loredana Bellantuono, Giuseppe Blasi, Qiang Chen, Joel E. Kleinman et al. · 2023 · Science Advances
- Multiple genes in a single GWAS risk locus synergistically mediate aberrant synaptic development and function in human neuronsZhang, Siwei, Zhang, Hanwen, Forrest, Marc P., Zhou, Yifan, Sun, Xiaotong, Bagchi, Vikram A., Kozlova, Alena, Santos, Marc Dos, Piguel, Nicolas H., Dionisio, Leonardo E. et al. · 2023 · Cell Genomics
- Molecular signatures of cortical expansion in the human foetal brainGareth Ball, Stuart Oldham, Vanessa Kyriakopoulou, Logan Z. J. Williams, Vyacheslav R. Karolis, Anthony N. Price, Jana Maria Hutter, Marc L. Seal, Aaron F. Alexander‐Bloch, Joseph V. Hajnal et al. · 2024 · Nature Communications
- Resolving the three-dimensional interactome of human accelerated regions during human and chimpanzee neurodevelopmentAtreyo Pal, Mark A. Noble, Matheo Morales, Richik Pal, Marybeth Baumgartner, Je Won Yang, Kristina Yim, Severin Uebbing, James P. Noonan · 2025 · Cell
- Global and Regional Development of the Human Cerebral Cortex: Molecular Architecture and Occupational AptitudesJean Shin, Shaojie Ma, Edith Hofer, Yash Patel, Daniel E. Vosberg, Steven Tilley, Gennady V. Roshchupkin, André M. M. Sousa, Xueqiu Jian, Rebecca Gottesman et al. · 2020 · Cerebral Cortex
- Joint epigenome profiling reveals cell-type-specific gene regulatory programmes in human cortical organoidsFlorian Noack, Silvia Vangelisti, Nora Ditzer, Faye Chong, Mareike Albert, Boyan Bonev · 2023 · Nature Cell Biology
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- The dynamics of chromatin architecture in brain development and functionIzabela Harabula, Ana Pombo · 2021 · Current Opinion in Genetics & Development
- Transcriptional-regulatory convergence across functional MDD risk variants identified by massively parallel reporter assaysBernard Mulvey, Joseph D. Dougherty · 2021 · Translational Psychiatry
- Epigenetic regulation during human cortical development: Seq-ing answers from the brain to the organoidEmily M. A. Lewis, Komal Kaushik, Luke A. Sandoval, Irene Antony, Sabine Dietmann, Kristen L. Kroll · 2021 · Neurochemistry International
- Analysis of chromatin accessibility in p53 deficient spermatogonial stem cells for high frequency transformation into pluripotent stateSitong Liu, Rui Wei, Hongyang Liu, Ruiqi Liu, Pengxiao Li, Xiaoyu Zhang, Wei Wei, Xiaodong Zhao, Xiaomeng Li, Yang Yang et al. · 2022 · Cell Proliferation
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- Molecular drivers of human cerebral cortical evolutionIkuo Suzuki · 2019 · Neuroscience Research
- Modern human changes in regulatory regions implicated in cortical developmentJuan Moriano, Cedric A. Boeckx · 2020 · BMC Genomics
- The growth factor EPIREGULIN promotes basal progenitor cell proliferation in the developing neocortexPaula Cubillos, Nora Ditzer, Annika Kolodziejczyk, Gustav Schwenk, Janine Hoffmann, Theresa M. Schütze, Răzvan Petru Derihaci, Cahit Birdir, Johannes E. M. Köllner, Andreas Petzold et al. · 2024 · The EMBO Journal
- Radionuclide partitioning coefficients in soils and plants and their correlation.Marsha I. Sheppard · 1985 · PubMed
- Single-cell multiomics atlas of organoid development uncovers longitudinal molecular programs of cellular diversification of the human cerebral cortexAna Uzquiano, Amanda J. Kedaigle, Martina Pigoni, Bruna da Silveira Paulsen, Xian Adiconis, Kwanho Kim, Tyler Faits, Surya Nagaraja, Noelia Antón-Bolaños, Chiara Gerhardinger et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- Normalization benchmark of ATAC-seq datasets shows the importance of accounting for GC-content effectsKoen Van den Berge, Hsin-Jung Chou, Hector Roux de Bézieux, Kelly Street, Davide Risso, John Ngai, Sandrine Dudoit · 2022 · Cell Reports Methods
- Massively parallel disruption of enhancers active in human neural stem cellsEvan T. Geller, Mark A. Noble, Matheo Morales, Jake Gockley, Deena Emera, Severin Uebbing, Justin L. Cotney, James P. Noonan · 2024 · Cell Reports
- Cortical cellular diversity and development in schizophreniaAmanda J. Price, Andrew E. Jaffe, Daniel R. Weinberger · 2020 · Molecular Psychiatry
- Schizophrenia-Linked Protein tSNARE1 Regulates Endosomal Trafficking in Cortical NeuronsMelissa Plooster, Guendalina Rossi, Martilias S. Farrell, Jessica C. McAfee, Jessica L. Bell, Michael Ye, Graham H. Diering, Hyejung Won, Stephanie L. Gupton, Patrick Brennwald · 2021 · Journal of Neuroscience
- Early developmental origins of cortical disorders modeled in human neural stem cellsXoel Mato-Blanco, Suel–Kee Kim, Alexandre Jourdon, Shaojie Ma, Sang-Hun Choi, Alice Maria Giani, Miguel I. Paredes, Andrew T.N. Tebbenkamp, Fuchen Liu, Alvaro Duque et al. · 2025 · Nature Communications
- Parsing the Functional Impact of Noncoding Genetic Variants in the Brain EpigenomeSamuel K. Powell, Callan P. O’Shea, Kristen Brennand, Schahram Akbarian · 2020 · Biological Psychiatry
- Artificial intelligence and placental DNA methylation: newborn prediction and molecular mechanisms of autism in preterm childrenRay O Bahado-Singh, Sangeetha Vishweswaraiah, Buket Aydas, Uppala Radhakrishna · 2021 · The Journal of Maternal-Fetal & Neonatal Medicine
- Using a comprehensive atlas and predictive models to reveal the complexity and evolution of brain-active regulatory elementsHenry Pratt, Gregory Andrews, Nicole Shedd, Nishigandha N. Phalke, T. Li, Anusri Pampari, Matthew Jensen, Cindy H. Wen, Michael J. Gandal, Daniel H. Geschwind et al. · 2024 · Science Advances
- Stimulating Wnt signaling reveals context-dependent genetic effects on gene regulation in primary human neural progenitorsNana Matoba, Brandon D. Le, Jordan M. Valone, Justin M. Wolter, Jessica T. Mory, Dan Liang, Nil Aygün, K. Alaine Broadaway, Marielle L. Bond, Karen L. Mohlke et al. · 2024 · Nature Neuroscience
- Oncogenic K-Ras suppresses global miRNA functionBing Shui, Tyler S. Beyett, Zhengyi Chen, Xiaoyi Li, Gaspare La Rocca, William Gazlay, Michael J. Eck, Ken S. Lau, Andrea Ventura, Kevin M. Haigis · 2023 · Molecular Cell
- Three‐dimensional genome structure and functionHao Liu, Hsiangyu Tsai, Maoquan Yang, Guozhi Li, Qian Bian, Gang Ding, Dandan Wu, Jiewen Dai · 2023 · MedComm
- Focus on Causality in ESC/iPSC-Based Modeling of Psychiatric DisordersAnke Hoffmann, Michael J. Ziller, Dietmar Spengler · 2020 · Cells
- Unveiling the Pathogenesis of Psychiatric Disorders Using Network ModelsYanning Zuo, Wei Don, Carissa Zhu, Ormina Naveed, Weizhe Hong, Xia Yang · 2021 · Genes
- Haplotype-specific MAPK3 expression in 16p11.2 deletion contributes to variable neurodevelopmentFang Liu, Liang Chen, Zhengchang Li, Sen Zhao, Haiming Yuan, Ruen Yao, Zailong Qin, Shaofang Shangguan, Shujie Zhang, Li‐Ping Zou et al. · 2023 · Brain
- Chromatin Remodeling in the Brain-a NuRDevelopmental OdysseySarah Larrigan, Sujay J. Shah, José Alex Lourenço Fernandes, Pierre A. Mattar · 2021 · International Journal of Molecular Sciences
- Comment on: What genes are differentially expressed in individuals with schizophrenia? A systematic reviewGabriel E. Hoffman, Andrew E. Jaffe, Michael J. Gandal, Leonardo Collado‐Torres, Solveig K. Sieberts, Bernie Devlin, Daniel H. Geschwind, Daniel R. Weinberger, Panos Roussos · 2022 · Molecular Psychiatry
- Orderly specification and precise laminar deployment of cortical glutamatergic projection neuron types through intermediate progenitorsDhananjay Huilgol, Jesse Maurica Levine, William Galbavy, Bor‐Shuen Wang, Z. Josh Huang · 2024 · Developmental Cell
- Regulatory landscape in brain development and diseaseKeeley Spiess, Hyejung Won · 2020 · Current Opinion in Genetics & Development
- Investigation of Schizophrenia with Human Induced Pluripotent Stem CellsSamuel K. Powell, Callan P. O’Shea, Sara Rose Shannon, Schahram Akbarian, Kristen Brennand · 2020 · Advances in neurobiology
- Novel Approaches for Identifying the Molecular Background of SchizophreniaArkadiy K. Golov, Nikolay V. Kondratyev, Georgiy P. Kostyuk, and Vera E. Golimbet · 2020 · Cells
- Targeted chromatin conformation analysis identifies novel distal neural enhancers of ZEB2 in pluripotent stem cell differentiationJudith C. Birkhoff, Rutger W. W. Brouwer, Petros Kolovos, Anne L. Korporaal, Ana Bermejo-Santos, Ilias Boltsis, Karol Nowosad, Mirjam C. G. N. van den Hout, Frank G. Grosveld, Wilfred F. J. van IJcken et al. · 2020 · Human Molecular Genetics
- The Landscape of Shared and Divergent Genetic Influences across 14 Psychiatric DisordersAndrew David Grotzinger, Josefin Werme, Wouter J. Peyrot, Oleksandr Frei, Christiaan A. de Leeuw, Lucy K. Bicks, Qiuyu Guo, Michael P. Margolis, Brandon J. Coombes, Anthony J. Batzler et al. · 2025 · medRxiv
- Three-dimensional chromatin organization in brain function and dysfunctionDileep, Vishnu, Tsai, Li-Huei · 2021 · Current Opinion in Neurobiology
- Characterization of De Novo Promoter Variants in Autism Spectrum Disorder with Massively Parallel Reporter AssaysJustin Koesterich, Joon‐Yong An, Fumitaka Inoue, Ajuni Sohota, Nadav Ahituv, Stephan Sanders, Anat Kreimer · 2023 · International Journal of Molecular Sciences
- High-mobility group nucleosomal binding domain 2 protects against microcephaly by maintaining global chromatin accessibility during corticogenesisXue-Ling Gao, Wen‐Jia Tian, Bofeng Liu, Jingyi Wu, Wei Xie, Qin Shen · 2019 · Journal of Biological Chemistry
- Transcriptome Analysis Identifies SenZfp536, a Sense LncRNA that Suppresses Self-renewal of Cortical Neural ProgenitorsKuan Tian, Andi Wang, Junbao Wang, Wei Li, Wenchen Shen, Yamu Li, Zhiyuan Luo, Ying Liu, Yan Zhou · 2020 · Neuroscience Bulletin
- Reorganization of postmitotic neuronal chromatin accessibility for maturation of serotonergic identityXinrui L. Zhang, W. Clay Spencer, Nobuko Tabuchi, Meagan M. Kitt, Evan S. Deneris · 2022 · eLife
- A multi-omics approach to visualize early neuronal differentiation from hESCs in 4DATHINA A. SAMARA, Mari Spildrejorde, Ankush Sharma, Martin Falck, Magnus Leithaug, Stefania Modafferi, P. M. Bjørnstad, Ganesh Acharya, Kristina Gervin, Robert Lyle et al. · 2022 · iScience
- Chromatin accessibility differences between alpha, beta, and delta cells identifies common and cell type-specific enhancersAlex M. Mawla, Talitha van der Meulen, Mark O. Huising · 2023 · BMC Genomics
- Genome scans of dog behavior implicate a gene network underlying psychopathology in mammals, including humansIsain Zapata, Erin E. Hecht, James A. Serpell, Carlos E. Alvarez · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- A single-cell multiomic analysis identifies molecular and gene-regulatory mechanisms dysregulated in developing Down syndrome neocortexCeline K. Vuong, Alexis Weber, Patrick Seong, Nana Matoba, Yu-Jen Chen, Jordan Peyer, Shahab Younesi, Angelo Salinda, Daniel Gomez, Gabriella Rivas et al. · 2026 · Science
- A single-cell survey unveils cellular heterogeneity and sensitive responses in mouse cortices induced by oral exposure to triphenyl phosphateDi Ji, Yuejin Yu, Qicheng Zhu, Xianjie Li, Xiali Zhong, Zhuyi Zhang, Weijian Ke, Congying Niu, Can Wang, Jingwei Wu et al. · 2022 · Archives of Toxicology
- Spatial genome exploration in the context of cognitive and neurological diseasePrashanth Rajarajan, Tyler M. Borrman, Will Liao, Sergio Espeso‐Gil, Sandhya Chandrasekaran, Yan Jiang, Zhiping Weng, Kristen Brennand, Schahram Akbarian · 2019 · Current Opinion in Neurobiology
- Cortical Neuron Migration and Dendrite Morphology are Regulated by Carboxypeptidase ELiang Chen, Damien Carrel, Anton Omelchenko, Hyuck Kim, Aashini Patel, Isabelle Fanget, Bonnie L. Firestein · 2018 · Cerebral Cortex
- Neurodevelopmental disorders and neurotoxicity: MicroRNA in focusAbhishek Jauhari, Tanisha Singh, Sanjay Yadav · 2022 · Journal of Chemical Neuroanatomy
- Improved single-cell ATAC-seq reveals chromatin dynamics of in vitro corticogenesisRyan M. Mulqueen, Brooke A. DeRosa, Casey A. Thornton, Zeynep Sayar, Kristof A. Torkenczy, Andrew J. Fields, Kevin M. Wright, Xiaolin Nan, Ramesh Ramji, Frank J. Steemers et al. · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
- Human-gained heart enhancers are associated with species-specific cardiac attributesEugin Destici, Fugui Zhu, Shaina Tran, Sebastian Preißl, Elie N. Farah, Yanxiao Zhang, Xiameng Hou, Olivier Poirion, Ah Young Lee, Jonathan D. Grinstein et al. · 2022 · Nature Cardiovascular Research
- A multi-regional human brain atlas of chromatin accessibility and gene expression facilitates promoter-isoform resolution genetic fine-mappingPengfei Dong, Liting Song, Jaroslav M. Bendl, Ruth Misir, Zhiping Shao, Jonathan Edelstien, David A. Davis, Vahram H. Haroutunian, William K. Scott, Susanne Acker et al. · 2024 · Nature Communications
- Individual-Level Identification of Gene Expression Associated with Volume Differences among Neocortical AreasJilian Fu, Feng Liu, Wen Qin, Qiang Xu, Chunshui Yu, Alzheimer’s Disease Neuroimaging Initiative · 2019 · Cerebral Cortex
- Lessons from single cell sequencing in CNS cell specification and functionZhen Li, William A. Tyler, Tarik F. Haydar · 2020 · Current Opinion in Genetics & Development
- A multi-layered integrative analysis reveals a cholesterol metabolic program in outer radial glia with implications for human brain evolutionJuan Moriano, Oliviero Leonardi, Alessandro Vitriolo, Giuseppe Testa, Cedric A. Boeckx · 2024 · Development
- Functional genomics links genetic origins to pathophysiology in neurodegenerative and neuropsychiatric diseaseBrie Wamsley, Daniel H. Geschwind · 2020 · Current Opinion in Genetics & Development
- Transcription Factor Motifs Associated with Anterior Insula Gene Expression Underlying Mood Disorder PhenotypesDhivya Arasappan, Simon Bodo Eickhoff, Charles B. Nemeroff, Hans A. Hofmann, Mbemba Jabbi · 2021 · Molecular Neurobiology
- Annotating functional effects of non-coding variants in neuropsychiatric cell types by deep transfer learningBen Lai, Sheng Qian, Hanwei Zhang, Siwei Zhang, Alena Kozlova, Jubao Duan, Xin He, Jinbo Xu · 2022 · PLoS Computational Biology
- Neuronal and glial 3D chromatin architecture illustrates cellular etiology of brain disordersBenxia Hu, Hyejung Won, Won Mah, Royce Park, Bibi S. Kassim, Keeley Spiess, Alexey Kozlenkov, Cheynna Crowley, Sirisha Pochareddy, Yun Li et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- Genetic and Epigenetic Regulation of Brain OrganoidsYouwei Wang, Nan Hu, Xiao-Hong Li · 2022 · Frontiers in Cell and Developmental Biology
- Dose rate dependent reduction in chromatin accessibility at transcriptional start sites long time after exposure to gamma radiationHildegunn Dahl, Jarle Ballangby, Torstein Tengs, Marcin Wlodzimierz Wojewodzic, Dag M. Eide, Dag Anders Brede, Anne Graupner, Nur Duale, Ann-Karin Hardie Olsen · 2023 · Epigenetics
- Functional genomics and systems biology in human neuroscienceGeneviève Konopka, Aparna Bhaduri · 2023 · Nature
- Druggable Transcriptional Networks in the Human Neurogenic EpigenomeGerald A. Higgins, Aaron M. Williams, Alex S. Ade, Hasan Badre Alam, Brian D. Athey · 2019 · Pharmacological Reviews
- Sites of active gene regulation in the prenatal frontal cortex and their role in neuropsychiatric disordersManuela R. Kouakou, Darren Cameron, Eilis J. Hannon, Emma Louise Dempster, Jonathan S. Mill, Matthew Hill, Nicholas J. Bray · 2021 · American Journal of Medical Genetics Part B Neuropsychiatric Genetics
- DeepGWAS: Enhance GWAS Signals for Neuropsychiatric Disorders via Deep Neural NetworkYun Li, Jia Wen, Gang Li, Jiawen Carmen Chen, Quan Sun, Weifang Liu, Wyliena Guan, Ben Lai, Jin Szatkiewicz, Xin He et al. · 2023 · Research Square
- Chromatin accessibility provides a window into the genetic etiology of human brain diseaseJaroslav M. Bendl, John F. Fullard, Kiran Girdhar, Pengfei Dong, Roman Kosoy, Biao Zeng, Gabriel E. Hoffman, Panos Roussos · 2025 · Trends in Genetics
- Single-nucleus multi-omics identifies shared and distinct pathways in Pick’s and Alzheimer’s diseaseZechuan Shi, Sudeshna Das, Samuel Morabito, Jennifer T. Stocksdale, Emily Miyoshi, Shushrruth Sai Srinivasan, Nora Emerson, Arshi Shahin, Negin Rahimzadeh, Zhenkun Cao et al. · 2025 · Science Advances
- Fetal alcohol spectrum disorder (FASD) affects the hippocampal levels of histone variant H2A.Z-2Taylor L. Gretzinger, Monica Varun Tyagi, Christine J. Fontaine, Manjinder S. Cheema, María González-Pérez, Melissa E. Freeman, Brian R. Christie, Juan Ausió · 2019 · Biochemistry and Cell Biology
- Comparison of chromatin accessibility landscapes during early development of prefrontal cortex between rhesus macaque and humanXuelong Yao, Zongyang Lu, Zhanying Feng, Lei Gao, Xin Zhou, Min Li, Suijuan Zhong, Qian Wu, Zhenbo Liu, Haofeng Zhang et al. · 2022 · Nature Communications
- Multiplexed functional genomic assays to decipher the noncoding genomeYonatan A. Cooper, Qiuyu Guo, Daniel H. Geschwind · 2022 · Human Molecular Genetics
- Regulatory and coding sequences of TRNP1 co-evolve with brain size and cortical folding in mammalsZane Kliesmete, Lucas Esteban Wange, Beate Vieth, Miriam Esgleas, Jessica Radmer, Matthias Hülsmann, Johanna Geuder, Daniel Richter, Mari Ohnuki, Magdalena Götz et al. · 2023 · eLife
- Massively parallel characterization of regulatory dynamics during neural inductionFumitaka Inoue, Anat Kreimer, Tal Ashuach, Nadav Ahituv, Nir Yosef · 2018 · bioRxiv (Cold Spring Harbor Laboratory)