Biological Functions of Autophagy Genes: A Disease Perspective

Cited by (1,006)

Items 601–700 of 1,006

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    Thomas Neill, Carolyn G. Chen, Simone Buraschi, Renato V. Iozzo · 2020 · Journal of Biological Chemistry
  2. PtdIns4P restriction by hydrolase SAC1 decides specific fusion of autophagosomes with lysosomes
    Hongjun Zhang, Jiao Zhou, Peng Xiao, Yong Lin, Xin Gong, Shiyan Liu, Qingjia Xu, Minjin Wang, Haiyan Ren, Mengji Lu et al. · 2020 · Autophagy
  3. Site-1 protease controls osteoclastogenesis by mediating LC3 transcription
    Zeyu Zheng, Xuyang Zhang, Bao Hua Huang, Junhui Liu, Xiaoan Wei, Zhi Shan, Hao Wu, Zhenhua Feng, Yilei Chen, Shunwu Fan et al. · 2021 · Cell Death and Differentiation
  4. Increased homocysteine regulated by androgen activates autophagy by suppressing the mammalian target of rapamycin pathway in the granulosa cells of polycystic ovary syndrome mice
    Ting Li, Guogang Dong, Yani Kang, Mei Zhang, Xiaoqiang Sheng, Zhilong Wang, Yang Liu, Na Kong, Haixiang Sun · 2022 · Bioengineered
  5. The Autophagy Machinery in Human-Parasitic Protists; Diverse Functions for Universally Conserved Proteins
    Hirokazu Sakamoto, Kumiko Nakada‐Tsukui, Sébastien Besteiro · 2021 · Cells
  6. Autophagy regulation in teleost fish: A double-edged sword
    Zhixia Zhou, Yanxin He, Shoushi Wang, Yin Wang, Peipei Shan, Peifeng Li · 2022 · Aquaculture
  7. Emerging mechanistic insights of selective autophagy in hepatic diseases
    Md. Abdul Alim Al‐Bari, Yuko Ito, Paul G. Thomes, Manoj B. Menon, Marina García Macia, Raouf Abdelrahman Fadel, Alfreda Stadlin, Nicholas Peake, MoezAlIslam E. Faris, Nabil A. S. Eid et al. · 2023 · Frontiers in Pharmacology
  8. HMGB1, angel or devil, in ischemic stroke
    Bin Gao, Shuwen Wang, Jiangfeng Li, Nannan Han, Hanming Ge, Gejuan Zhang, Mingze Chang · 2023 · Brain and Behavior
  9. Thymoquinone induces apoptosis and protective autophagy in gastric cancer cells by inhibiting the PI3K /Akt/ mTOR pathway
    Pengzhan He, Yang He, Jingjing Ma, Yinghui Liu, Chuan Liu, Baoping Yu, Dong Wei-guo · 2023 · Phytotherapy Research
  10. SDC1-TGM2-FLOT1-BHMT complex determines radiosensitivity of glioblastoma by influencing the fusion of autophagosomes with lysosomes
    Liang Zeng, Zheng Wang, Xinglong Liu, Yuchuan Zhou, Xiaoya Jin, Yuqi Xiao, Yang Bai, Yan Pan, Jianghong Zhang, Chunlin Shao · 2023 · Theranostics
  11. Oxidative stress drives vascular smooth muscle cell damage in acute Stanford type A aortic dissection through HIF-1α/HO-1 mediated ferroptosis
    Wenyu Song, Yifu Chen, Lieyang Qin, Xinyuan Xu, Yu Sun, Mingzhu Zhong, Yuntao Lu, Kui Ru Hu, Lai Wei, Jinmiao Chen · 2023 · Heliyon
  12. Human YKT6 forms priming complex with STX17 and SNAP29 to facilitate autophagosome-lysosome fusion
    Denghao Zheng, Mindan Tong, Shen Zhang, Yi Pan, Yanxiang Zhao, Qing Zhong, Xiaoxia Liu · 2024 · Cell Reports
  13. Proteostasis in neurodegenerative diseases
    Sumit Kinger, Yuvraj Anandrao Jagtap, Prashant Kumar, Akash Choudhary, Amit Prasad, Vijay Kumar Prajapati, Amit Kumar, Gunjan Mehta, Amit Mishra · 2024 · Advances in clinical chemistry
  14. Machine learning-based biomarker screening for acute myeloid leukemia prognosis and therapy from diverse cell-death patterns
    Yu Qin, Xuexue Pu, Dingtao Hu, Mingzhen Yang · 2024 · Scientific Reports
  15. Early host defense against virus infections
    Søren R. Paludan, Thomas Pradeu, Andreas Pichlmair, K. Brad Wray, Jacob Giehm Mikkelsen, David P. Olagnier, Trine Hyrup Mogensen · 2024 · Cell Reports
  16. Pharmacological Mechanisms of Cryptotanshinone: Recent Advances in Cardiovascular, Cancer, and Neurological Disease Applications
    Ziyao Zheng, Liyuan Ke, Shumin Ye, Peiying Shi, Hong Yao · 2024 · Drug Design Development and Therapy
  17. The Complex Role of Autophagy in Melanoma Evolution: New Perspectives From Mouse Models
    Luca Di Leo, Valérie Bodemeyer, Daniela De Zio · 2020 · Frontiers in Oncology
  18. Exaggerated Autophagy in Stanford Type A Aortic Dissection: A Transcriptome Pilot Analysis of Human Ascending Aortic Tissues
    Zeyi Zhou, Yan Liu, Xiyu Zhu, Xinlong Tang, Yali Wang, Junxia Wang, Can Xu, Dongjin Wang, Jie Du, Qing Zhou · 2020 · Genes
  19. The ubiquitin isopeptidase USP10 deubiquitinates LC3B to increase LC3B levels and autophagic activity
    Rui Jia, Juan S. Bonifacino · 2021 · Journal of Biological Chemistry
  20. TFEB regulates pluripotency transcriptional network in mouse embryonic stem cells independent of autophagy–lysosomal biogenesis
    Anderson Tan, Renuka Prasad, Eek‐hoon Jho · 2021 · Cell Death and Disease
  21. Aconiti Lateralis Radix Praeparata as Potential Anticancer Herb: Bioactive Compounds and Molecular Mechanisms
    Wen Zhang, Chaoying Lu, Shuhui Cai, Yaru Feng, Jinjun Shan, Liuqing Di · 2022 · Frontiers in Pharmacology
  22. A supramolecular self-assembled nanomaterial for synergistic therapy of immunosuppressive tumor
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  23. On the wake of metformin: Do anti-diabetic SGLT2 inhibitors exert anti-aging effects?
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  24. Acyl-CoA-binding protein (ACBP): the elusive ‘hunger factor’ linking autophagy to food intake
    José Manuel Bravo‐San Pedro, Valentina Sica, Frank Madeo, Guido Kroemer · 2019 · Cell Stress
  25. MK8722 initiates early-stage autophagy while inhibiting late-stage autophagy via FASN-dependent reprogramming of lipid metabolism
    Luhui Wang, Haiyan Zhu, Zhehao Shi, Bo Chen, Huirong Huang, Ganglian Lin, Jiacheng Li, Haitao Yu, Shihao Xu, Gang Chen et al. · 2023 · Theranostics
  26. Autophagy pathways in the treatment of prion diseases
    Dalia H. Abdelaziz, Basant Abdulrahman, Sabine Gilch, Hermann M. Schätzl · 2019 · Current Opinion in Pharmacology
  27. Autophagy Deficiency Leads to Impaired Antioxidant Defense via p62-FOXO1/3 Axis
    Lin Zhao, Hao Li, Yan Wang, Adi Zheng, Liu Cao, Jiankang Liu · 2019 · Oxidative Medicine and Cellular Longevity
  28. Ion Channels and Transporters in Autophagy
    Ruoxi Zhang, Rui Kang, Daniel J. Klionsky, Daolin Tang · 2021 · Autophagy
  29. DDRGK1, a crucial player of ufmylation system, is indispensable for autophagic degradation by regulating lysosomal function
    Yan Cao, Rongyang Li, Ming Shen, Chengyu Li, Yan Zou, Qiang Jiang, Shuo Liu, Chunwan Lu, Honglin Li, Honglin Liu et al. · 2021 · Cell Death and Disease
  30. The autophagy protein ATG16L1 cooperates with IFT20 and INPP5E to regulate the turnover of phosphoinositides at the primary cilium
    Asma Boukhalfa, Federica Roccio, Nicolas Dupont, Patrice Codogno, Étienne Morel · 2021 · Cell Reports
  31. Imperatorin induces autophagy and G0/G1 phase arrest via PTEN-PI3K-AKT-mTOR/p21 signaling pathway in human osteosarcoma cells in vitro and in vivo
    Minchao Lv, Qingxin Xu, Bei Zhang, Zhiqiang Yang, Jun Xie, Jinku Guo, Feixiong He, Wei Wang · 2021 · Cancer Cell International
  32. Evaluation of potential cardiotoxicity of ammonia: l-selenomethionine inhibits ammonia-induced cardiac autophagy by activating the PI3K/AKT/mTOR signaling pathway
    Zheng Cheng, Yufu Shu, Xin Li, Yutao Li, Sitong Zhou, Honggui Liu · 2022 · Ecotoxicology and Environmental Safety
  33. Cholesterol suppresses GOLM1-dependent selective autophagy of RTKs in hepatocellular carcinoma
    Weiqing Shao, Wenwei Zhu, Meng-Jun Luo, Ming-Hao Fan, Qin Li, Shenghao Wang, Zhifei Lin, Jing Zhao, Yan Zheng, Qiongzhu Dong et al. · 2022 · Cell Reports
  34. Cleavage of the selective autophagy receptor SQSTM1/p62 by the SARS-CoV-2 main protease NSP5 prevents the autophagic degradation of viral membrane proteins
    Yabin Zhang, Shiyan Liu, Qingjia Xu, Huihui Li, Kefeng Lu · 2022 · Molecular Biomedicine
  35. Long non-coding RNA HOXA11-AS knockout inhibits proliferation and overcomes drug resistance in ovarian cancer
    Yuwei Chen, Zhaolei Cui, Qiaoling Wu, Huihui Helen Wang, Hongmei Xia, Yang Sun · 2022 · Bioengineered
  36. Molecular regulation and therapeutic implications of cell death in pulmonary hypertension
    Enze Wang, Sijing Zhou, Daxiong Zeng, Ran Wang · 2023 · Cell Death Discovery
  37. Recent Advances in the Role of Autophagy in Endocrine-Dependent Tumors
    Anvita Komarla, Suzanne Dufresne, Christina G. Towers · 2023 · Endocrine Reviews
  38. Melatonin inhibits fibroblast cell functions and hypertrophic scar formation by enhancing autophagy through the MT2 receptor-inhibited PI3K/Akt /mTOR signaling
    Yunxian Dong, Xiaoling Cao, Jinsheng Huang, Zhicheng Hu, Chufen Chen, Miao Chen, Long Qian, Zhongye Xu, Dongming Lv, Yanchao Rong et al. · 2023 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  39. Unraveling Histone Loss in Aging and Senescence
    Sushil Kumar Dubey, Rashmi Dubey, Mark Ellsworth Kleinman · 2024 · Cells
  40. TRIM27 elicits protective immunity against tuberculosis by activating TFEB-mediated autophagy flux
    Dongdong Zhao, Lihua Qiang, Zehui Lei, Pupu Ge, Zhe Lü, Yiru Wang, Xinwen Zhang, Yuyun Qiang, Bingxi Li, Yu Pang et al. · 2024 · Autophagy
  41. Sulfur-based fluorescent probes for biological analysis: A review
    Guodong Hu, Hua-dong Xu, Jianguo Fang · 2024 · Talanta
  42. Shaoyao-Gancao Decoction, a famous Chinese medicine formula, protects against APAP-induced liver injury by promoting autophagy/mitophagy
    Yuelan Wu, Wenxuan Li, Jinghao Zhang, Jiacheng Lin, Liping You, Jian Su, Chao Zheng, Yueqiu Gao, Xiaoni Kong, Xuehua Sun · 2024 · Phytomedicine
  43. Microfluidic chip and its application in autophagy detection
    Xiaobo Wang, Zixuan Liu, Fangfang Fan, Ya Hou, Hailing Yang, Xianli Meng, Yi Zhang, Fugang Ren · 2019 · TrAC Trends in Analytical Chemistry
  44. Simvastatin alleviated diabetes mellitus‐induced erectile dysfunction in rats by enhancing AMPK pathway‐induced autophagy
    Fan Ding, Changyu Shan, Hongwei Li, Yuping Zhang, Chunling Guo, Zhansong Zhou, Ji Zheng, Wenhao Shen, Qiang Dai, Qin Ouyang et al. · 2020 · Andrology
  45. The mito-QC Reporter for Quantitative Mitophagy Assessment in Primary Retinal Ganglion Cells and Experimental Glaucoma Models
    Ines Rosignol, Beatriz Villarejo‐Zori, Petra Terešak, Elena Sierra‐Filardi, Xandra Pereiro, Natalia Rodríguez‐Muela, Elena Vecino, Helena L.A. Vieira, Katharina Cornelia Bell, Patricia Boya · 2020 · International Journal of Molecular Sciences
  46. Secretory proteostasis of the retinal pigmented epithelium: Impairment links to age-related macular degeneration
    Luminita Paraoan, Umar Sharif, Emil Carlsson, Wasu Supharattanasitthi, Nur Musfirah Mahmud, Tengku Ain Kamalden, Paul Stephenson Hiscott, Malcolm Joseph Jackson, Ian Grierson · 2020 · Progress in Retinal and Eye Research
  47. Mechanisms of Action of Autophagy Modulators Dissected by Quantitative Systems Pharmacology Analysis
    Qingya Shi, Fen Pei, Gary A. Silverman, Stephen C. Pak, David H. Perlmutter, Bing Liu, İvet Bahar · 2020 · International Journal of Molecular Sciences
  48. Biological Factors, Metals, and Biomaterials Regulating Osteogenesis through Autophagy
    Viviana di Giacomo, Amelia Cataldi, Silvia Sancilio · 2020 · International Journal of Molecular Sciences
  49. Friend or Enemy: A Dual Role of Autophagy in Plant Virus Infection
    Xiuqin Huang, Siping Chen, Xiaorong Yang, Xin Yang, Tong Zhang, Guohui Zhou · 2020 · Frontiers in Microbiology
  50. A conserved myotubularin-related phosphatase regulates autophagy by maintaining autophagic flux
    Elizabeth A. Allen, Clelia Amato, Tina M. Fortier, Panagiotis D. Velentzas, Will Wood, Eric H. Baehrecke · 2020 · The Journal of Cell Biology
  51. Plant Rho GTPase signaling promotes autophagy
    Youshun Lin, Yonglun Zeng, Ying Zhu, Jinbo Shen, Hao Ye, Liwen Jiang · 2021 · Molecular Plant
  52. Phosphorylation of the LIR Domain of SCOC Modulates ATG8 Binding Affinity and Specificity
    Martina Wirth, Stéphane Mouilleron, Wenxin Zhang, Eva Sjøttem, Yakubu Princely Abudu, Ashish Jain, Hallvard Lauritz Olsvik, Jack‐Ansgar Bruun, Minoo Razi, Harold B.J. Jefferies et al. · 2021 · Journal of Molecular Biology
  53. Esomeprazole inhibits hypoxia/endothelial dysfunction–induced autophagy in preeclampsia
    Shengyi Gu, Chenchen Zhou, Jindan Pei, Yuelin Wu, Sheng Wan, Xiaobo Zhao, Junhao Hu, Xiaolin Hua · 2022 · Cell and Tissue Research
  54. Adenosine A2a Receptor Regulates Autophagy Flux and Apoptosis to Alleviate Ischemia-Reperfusion Injury via the cAMP/PKA Signaling Pathway
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  55. Impaired autophagy promotes hair loss in the C3H/HeJ mouse model of alopecia areata
    Rupali Gund, Angela M. Christiano · 2022 · Autophagy
  56. NLRP3 Inflammasome in Atherosclerosis: Putting Out the Fire of Inflammation
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  57. Targeting the ATG5-ATG16L1 Protein–Protein Interaction with a Hydrocarbon-Stapled Peptide Derived from ATG16L1 for Autophagy Inhibition
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  58. How autophagy, a potential therapeutic target, regulates intestinal inflammation
    Shuang-Lan Chen, Chunmeng Li, Wei Li, Qingsong Liu, Shuangyuan Hu, Maoyuan Zhao, Dong-Sen Hu, Yanwei Hao, Jinhao Zeng, Yi Zhang · 2023 · Frontiers in Immunology
  59. Hesperidin Reversed Long-Term N-methyl-N-nitro-N-Nitroguanidine Exposure Induced EMT and Cell Proliferation by Activating Autophagy in Gastric Tissues of Rats
    Zhaofeng Liang, Jiajia Song, Yumeng Xu, Xinyi Zhang, Yue Zhang, Hui Qian · 2022 · Nutrients
  60. Photodynamic Therapy for Inflammatory and Cancerous Diseases of the Intestines: Molecular Mechanisms and Prospects for Application
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  61. Biomimetic Metal–Organic Framework Combats Biofilm‐Associated Infections via Hyperthermia‐Enhanced Bacterial Metabolic Interference and Autophagy‐Promoted Adaptive Immunity
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  92. Stromal cell‐derived small extracellular vesicles enhance radioresistance of prostate cancer cells via interleukin‐8‐induced autophagy
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  94. Therapeutic potential of autophagy in immunity and inflammation: current and future perspectives
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  95. Autophagy-mediated ferroptosis involved in nickel-induced nephrotoxicity in the mice
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  100. Mitophagy: A New Player in Stem Cell Biology
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