Biological Functions of Autophagy Genes: A Disease Perspective

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Items 301–400 of 1,006

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2. Isoginkgetin, a potential CDK6 inhibitor, suppresses SLC2A1/GLUT1 enhancer activity to induce AMPK-ULK1-mediated cytotoxic autophagy in hepatocellular carcinoma
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3. Cell deaths: Involvement in the pathogenesis and intervention therapy of COVID-19
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4. Diabetes mellitus and the impairment of male reproductive function: Possible signaling pathways
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5. Mitophagy Receptors in Tumor Biology
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6. Epg5 deficiency leads to primary ovarian insufficiency due to WT1 accumulation in mouse granulosa cells
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7. Mechanisms of sepsis-induced acute liver injury: a comprehensive review
   Yongjing Guo, Wanxu Guo, Huimin Chen, Jian Sun, Yongjie Yin · 2025 · Frontiers in Cellular and Infection Microbiology
8. Essential role for autophagy protein ATG7 in the maintenance of intestinal stem cell integrity
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9. Regulation and repurposing of nutrient sensing and autophagy in innate immunity
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10. The Role of Autophagy in Gastric Cancer Chemoresistance: Friend or Foe?
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11. Autophagy deficiency in neurodevelopmental disorders
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12. Selective Autophagy of the Protein Homeostasis Machinery: Ribophagy, Proteaphagy and ER-Phagy
    Carsten Jörn Beese, Sólveig Hlín Brynjólfsdóttir, Lisa B. Frankel · 2020 · Frontiers in Cell and Developmental Biology
13. Comprehensive autophagy evaluation in cardiac disease models
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14. Autophagy–virus interplay in plants: from antiviral recognition to proviral manipulation
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15. Potential benefits of combination of Nigella sativa and Zn supplements to treat COVID-19
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16. A thermosensitive, reactive oxygen species-responsive, MR409-encapsulated hydrogel ameliorates disc degeneration in rats by inhibiting the secretory autophagy pathway
    Qiangqiang Zheng, Haotian Shen, Zongrui Tong, Linxiang Cheng, Yuzi Xu, Zhiyun Feng, Shiyao Liao, Xiaojian Hu, Zongyou Pan, Zhengwei Mao et al. · 2020 · Theranostics
17. Autophagy regulation using luteolin: new insight into its anti-tumor activity
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18. Sirtuin 4 activates autophagy and inhibits tumorigenesis by upregulating the p53 signaling pathway
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19. NR3C1/Glucocorticoid receptor activation promotes pancreatic β-cell autophagy overload in response to glucolipotoxicity
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20. PCDH17 Increases the Sensitivity of Colorectal Cancer to 5-Fluorouracil Treatment by Inducing Apoptosis and Autophagic Cell Death
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21. Therapeutic modulation of autophagy: which disease comes first?
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22. Mechanical Stress-Dependent Autophagy Component Release via Extracellular Nanovesicles in Tumor Cells
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23. Autophagy Is Required for Maturation of Surfactant-Containing Lamellar Bodies in the Lung and Swim Bladder
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24. Autophagy in liver diseases
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25. Cross talk between autophagy and oncogenic signaling pathways and implications for cancer therapy
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26. Autophagic elimination of ribosomes during spermiogenesis provides energy for flagellar motility
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27. Ajugol enhances TFEB-mediated lysosome biogenesis and lipophagy to alleviate non-alcoholic fatty liver disease
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28. Therapeutic targeting of the USP2-E2F4 axis inhibits autophagic machinery essential for zinc homeostasis in cancer progression
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29. Adipose mesenchymal stem cell-derived exosomes promote skin wound healing in diabetic mice by regulating epidermal autophagy
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30. The Aging Heart: Mitophagy at the Center of Rejuvenation
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31. Role of mTOR-Regulated Autophagy in Synaptic Plasticity Related Proteins Downregulation and the Reference Memory Deficits Induced by Anesthesia/Surgery in Aged Mice
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32. Atg8ylation as a general membrane stress and remodeling response
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33. Regulation of Autophagy by the Glycogen Synthase Kinase-3 (GSK-3) Signaling Pathway
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34. Emerging Roles and Mechanism of m6A Methylation in Cardiometabolic Diseases
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35. PI(18:1/18:1) is a SCD1-derived lipokine that limits stress signaling
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36. Biomedical application of aggregation-induced emission luminogen-based fluorescent sensors
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37. New insights into autophagy in hepatocellular carcinoma: mechanisms and therapeutic strategies.
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38. The interplay between emerging human coronavirus infections and autophagy
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39. PLK1 Inhibition Sensitizes Breast Cancer Cells to Radiation via Suppressing Autophagy
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40. Current insights into the implications of m6A RNA methylation and autophagy interaction in human diseases
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41. USP19 (ubiquitin specific peptidase 19) promotes TBK1 (TANK-binding kinase 1) degradation via chaperone-mediated autophagy
    Xibao Zhao, Qianqian Di, Juan Yu, Jiazheng Quan, Yue Xiao, Huihui Zhu, Hongrui Li, Ling Jing, Weilin Chen · 2021 · Autophagy
42. The Interplay between Autophagy and NLRP3 Inflammasome in Ischemia/Reperfusion Injury
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43. Mucopolysaccharidoses: Cellular Consequences of Glycosaminoglycans Accumulation and Potential Targets
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44. Lysosomes as a Target of Anticancer Therapy
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45. Analysis of multiple programmed cell death-related prognostic genes and functional validations of necroptosis-associated genes in oesophageal squamous cell carcinoma
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46. A switch element in the autophagy E2 Atg3 mediates allosteric regulation across the lipidation cascade
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47. Interfering with Autophagy: The Opposing Strategies Deployed by Legionella pneumophila and Coxiella burnetii Effector Proteins
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48. Heparan sulfate is a clearance receptor for aberrant extracellular proteins
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49. Phytopathogen Effectors Use Multiple Mechanisms to Manipulate Plant Autophagy
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50. ATG16L1 functions in cell homeostasis beyond autophagy
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51. Exosomes, autophagy and ER stress pathways in human diseases: Cross-regulation and therapeutic approaches
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52. Autophagosome biogenesis machinery.
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53. Targeting Autophagy to Treat Cancer: Challenges and Opportunities
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54. Advances in indole-containing alkaloids as potential anticancer agents by regulating autophagy
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55. Copper Toxicity in Animals: A Review
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56. Autophagy in Myelinating Glia
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57. TLR9 in MAFLD and NASH: At the Intersection of Inflammation and Metabolism
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58. Mammalian Atg8 proteins regulate lysosome and autolysosome biogenesis through SNAREs
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59. Development of Prognostic Indicator Based on Autophagy‐Related lncRNA Analysis in Colon Adenocarcinoma
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60. A review: Pharmacology and pharmacokinetics of Schisandrin A
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61. Interaction between autophagy and the NLRP3 inflammasome in Alzheimer’s and Parkinson’s disease
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62. Effects of Time-Restricted Feeding and Ramadan Fasting on Body Weight, Body Composition, Glucose Responses, and Insulin Resistance: A Systematic Review of Randomized Controlled Trials
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63. Mass spectrometry proteomics reveals a function for mammalian CALCOCO1 in MTOR-regulated selective autophagy
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64. Autophagy in cancers including brain tumors: role of MicroRNAs
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65. The role of TRIM family proteins in autophagy, pyroptosis, and diabetes mellitus
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66. Pharmacological inhibition of USP30 activates tissue‐specific mitophagy
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67. Structural basis for membrane recruitment of ATG16L1 by WIPI2 in autophagy
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70. Selective autophagy of AKAP11 activates cAMP/PKA to fuel mitochondrial metabolism and tumor cell growth
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71. Autophagy sustains glutamate and aspartate synthesis in Saccharomyces cerevisiae during nitrogen starvation
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72. Targeting reactive oxygen species in stem cells for bone therapy
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73. Evidence for Lysosomal Dysfunction within the Epidermis in Psoriasis and Atopic Dermatitis
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74. BNIP3-Dependent Mitophagy via PGC1α Promotes Cartilage Degradation
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75. Regulation of Endoplasmic Reticulum Stress-Autophagy: A Potential Therapeutic Target for Ulcerative Colitis
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78. Dexmedetomidine Ameliorates Cardiac Ischemia/Reperfusion Injury by Enhancing Autophagy Through Activation of the AMPK/SIRT3 Pathway
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79. The Role of ATG9 Vesicles in Autophagosome Biogenesis
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80. ZDHHC7-mediated S -palmitoylation of ATG16L1 facilitates LC3 lipidation and autophagosome formation
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89. Selective Autophagy by Close Encounters of the Ubiquitin Kind
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90. Autophagy in Multiple Sclerosis: Two Sides of the Same Coin
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91. Let-7f miRNA regulates SDF-1α- and hypoxia-promoted migration of mesenchymal stem cells and attenuates mammary tumor growth upon exosomal release
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95. Degrons: defining the rules of protein degradation
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96. Autophagy: New Insights into Mechanisms of Action and Resistance of Treatment in Acute Promyelocytic leukemia
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97. Promoting Reactive Oxygen Species Generation: A Key Strategy in Nanosensitizer-Mediated Radiotherapy
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98. Mechanisms of TLR4-Mediated Autophagy and Nitroxidative Stress
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99. Intrinsic Mechanisms Regulating Neuronal Migration in the Postnatal Brain
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100. Tumor Cell Derived Lnc‐FSD2‐31:1 Contributes to Cancer‐Associated Fibroblasts Activation in Pancreatic Ductal Adenocarcinoma Progression through Extracellular Vesicles Cargo MiR‐4736
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