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Cell Membranes Resist Flow
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Abstract
The fluid-mosaic model posits a liquid-like plasma membrane, which can flow in response to tension gradients. It is widely assumed that membrane flow transmits local changes in membrane tension across the cell in milliseconds, mediating long-range signaling. Here, we show that propagation of membrane tension occurs quickly in cell-attached blebs but is largely suppressed in intact cells. The failure of tension to propagate in cells is explained by a fluid dynamical model that incorporates the flow resistance from cytoskeleton-bound transmembrane proteins. Perturbations to tension propagate diffusively, with a diffusion coefficient D σ ∼0.024 μm 2/s in HeLa cells. In primary endothelial cells, local increases in membrane tension lead only to local activation of mechanosensitive ion channels and to local vesicle fusion. Thus, membrane tension is not a mediator of long-range intracellular signaling, but local variations in tension mediate distinct processes in sub-cellular domains.
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“Indeed, a substantial spatial gradient of membrane tension is thought to persist due to attachment of cytoskeleton to the membrane28.”
From Membrane compression by synaptic vesicle exocytosis triggers ultrafast endocytosis (2023) · cites this paper as [28]
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Cites
The Fluid Mosaic Model of the Structure of Cell Membranes
Singer, S. J., & Nicolson, G. L. (1972) · Science · doi:10.1126/science.175.4023.720 · Cited by 9,158
Ultrasensitive fluorescent proteins for imaging neuronal activity
Chen, T.-W., Wardill, T. J., Sun, Y., Pulver, S. R., Renninger, S. L., Baohan, A., Schreiter, E. R., Kerr, R. A., Orger, M. B., Jayaraman, V., et al. (2013) · Nature · doi:10.1038/nature12354 · Cited by 6,474
Brownian motion in biological membranes
Saffman, P. G., & Delbrück, M. (1975) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.72.8.3111 · Cited by 1,773
Micropipette aspiration of living cells
Hochmuth, R. M. (2000) · Journal of Biomechanics · doi:10.1016/s0021-9290(99)00175-x · Cited by 1,428
Piezo1 integration of vascular architecture with physiological force
Li, J., Hou, B., Tumova, S., Muraki, K., Bruns, A. F., Ludlow, M. J., Sedó, A., Hyman, A. J., McKeown, L., Young, R. S., et al. (2014) · Nature · doi:10.1038/nature13701 · Cited by 1,250
Phases and phase transitions of the phosphatidylcholines
Koynova, R. D., & Caffrey, M. (1998) · Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes · doi:10.1016/s0304-4157(98)00006-9 · Cited by 1,155
Entropy-driven tension and bending elasticity in condensed-fluid membranes
Evans, E., & Rawicz, W. (1990) · Physical Review Letters · doi:10.1103/physrevlett.64.2094 · Cited by 1,129
Kusumi, A., Nakada, C., Ritchie, K. P., Murase, K., Suzuki, K. G. N., Murakoshi, H., Kasai, R. S., Kondo, J., & Fujiwara, T. K. (2005) · Annual Review of Biophysics and Biomolecular Structure · doi:10.1146/annurev.biophys.34.040204.144637 · Cited by 1,122
Improving the photostability of bright monomeric orange and red fluorescent proteins
Shaner, N. C., Lin, M. Z., McKeown, M. R., Steinbach, P. A., Hazelwood, K. L., Davidson, M. W., & Tsien, R. Y. (2008) · Nature Methods · doi:10.1038/nmeth.1209 · Cited by 994
Emerging roles for lipids in shaping membrane-protein function
Phillips, R., Ursell, T. S., Wiggins, P. A., & Sens, P. (2009) · Nature · doi:10.1038/nature08147 · Cited by 988
Flagged first, then by citations
3 of the 95 references couldn’t be matched to a known paper.
Research works printed but not linked: 2
- Ellefsen, 2018, Piezo1 calcium flickers localize to hotspots of cellular traction forces, bioRxiv
- Thottacherry, 2017, Mechanochemical feedback and control of endocytosis and membrane tension, bioRxiv
Cited by
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Items 201–300 of 355
He, W., Su, Y., Peng, H. B., & Tong, P. (2020) · Molecular Biology of the Cell · doi:10.1091/mbc.e19-08-0473 · Cited by 7
Self-Assembled Ru(II)-Coumarin Complexes for Selective Cell Membrane Imaging
Liu, J., Xie, X., Lu, J., He, Y., Shao, D., & Chen, F. (2022) · Pharmaceutics · doi:10.3390/pharmaceutics14112284 · Cited by 7
Sabri, E., & Brosseau, C. (2023) · Bioelectrochemistry · doi:10.1016/j.bioelechem.2023.108583 · Cited by 7
Regulation of global CD8+ T‐cell positioning by the actomyosin cytoskeleton
Stein, J. V., & Ruef, N. (2019) · Immunological Reviews · doi:10.1111/imr.12759 · Cited by 7
The impact of altered mechanobiology on aortic valve pathophysiology
Bardon, K. M., & Garelnabi, M. (2020) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2020.108463 · Cited by 9
Li, J., Lv, F., & Jin, T. (2022) · Frontiers in Neurology · doi:10.3389/fneur.2022.1024869 · Cited by 7
Adaptive actin organization buffers endocytosis against changes in membrane tensionPreprint
Kaplan, C., Kenny, S. J., Chen, S. C., Schöneberg, J., Sitarska, E., Diz-Muñoz, A., Akamatsu, M., Xu, K., & Drubin, D. (2020) · bioRxiv · doi:10.1101/2020.04.05.026559 · Cited by 4
Signaling and actin waves at a glance
Banerjee, T., Deng, Y., Pal, D. S., Zhan, H., Iglesias, P. A., & Devreotes, P. N. (2025) · Journal of Cell Science · doi:10.1242/jcs.263634 · Cited by 6
Adherent cells sustain membrane tension gradients independently of migration
ARCOS, J. M. G., Mehidi, A., Sánchez‐Velásquez, J. J., Guillamat, P., Tomba, C., Houzet, L., Capolupo, L., Espadas, J., D’Angelo, G., Colom, A., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-65571-9 · Cited by 6
Singh, V., Breton, V., de Lesegno, C. V., Macé, A., Bun, P., Blouin, C. M., Vishen, A. S., Sens, P., & Lamaze, C. (2025) · Nature Communications · doi:10.1038/s41467-025-67090-z · Cited by 6
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Ratajczak, A. M., Sasidharan, S., Gonzalez, X. I. R., Miller, E. J., Socrier, L., Anthony, A. A., & Honerkamp‐Smith, A. R. (2023) · Biophysical Journal · doi:10.1016/j.bpj.2023.03.042 · Cited by 6
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Fitz, G. N., & Tyska, M. J. (2024) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2024.107934 · Cited by 6
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Kostyk, S., Shybetskyy, V., Fesenko, S. V., & Povodzinskiy, V. (2019) · Eastern-European Journal of Enterprise Technologies · doi:10.15587/1729-4061.2019.156649 · Cited by 6
Microtubule-independent movement of the fission yeast nucleus
Ashraf, S., Tay, Y. D., Kelly, D. A., & Sawin, K. E. (2021) · Journal of Cell Science · doi:10.1242/jcs.253021 · Cited by 6
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Matsubayashi, H. T., Razavi, S., Tahara, Y. O., Akenuwa, O. H., Rock, T. W., Nakajima, D., Otsuka-Yamaguchi, R., Nakamura, H., Kramer, D. A., Matsuura, T., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.10.14.617543 · Cited by 6
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Lira, R. B., Cavalcanti, R. R. M., Riske, K. A., & Dimova, R. (2026) · Biophysical Journal · doi:10.1016/j.bpj.2026.07.012 · Cited by 7
Mechanical plasticity of cell membranes enhances epithelial wound closure
Ton, A. T., MacKeith, A. K., Shattuck, M. D., & O’Hern, C. S. (2024) · Physical Review Research · doi:10.1103/physrevresearch.6.l012036 · Cited by 7
Li, S., Yan, Z., Huang, F. L., Zhang, X., & Yue, T. (2019) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2019.110651 · Cited by 5
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Zmurchok, C., & Holmes, W. R. (2022) · Bulletin of Mathematical Biology · doi:10.1007/s11538-022-00997-6 · Cited by 5
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Buwa, N., & Balasubramanian, N. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-90195-6.00019-x · Cited by 5
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Mierke, C. T. (2024) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/bs.mie.2023.12.007 · Cited by 6
Absolute vs Convective Instabilities and Front Propagation in Lipid Membrane Tubes
Tchoufag, J., Sahu, A., & Mandadapu, K. K. (2022) · Physical Review Letters · doi:10.1103/physrevlett.128.068101 · Cited by 5
Tupin, S., Saqr, K. M., Rashad, S., Niizuma, K., Ohta, M., & Tominaga, T. (2020) · arXiv (Cornell University) · doi:10.48550/arxiv.2001.08234 · Cited by 5
Rashid, F., & Wang, N. (2026) · Mechanobiology in medicine · doi:10.1016/j.mbm.2026.100179 · Cited by 4
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Xu, D., Yang, Y., Emmerich, L., Wang, Y., & Zhang, K. (2023) · Nature Communications · doi:10.1038/s41467-023-41738-0 · Cited by 4
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Xie, W., Kong, Y., Ren, C., Wen, Y., Ying, M., & Xing, H. (2024) · Chemical Communications · doi:10.1039/d4cc05186f · Cited by 4
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Raj, N., & Gerke, V. (2025) · Trends in Cell Biology · doi:10.1016/j.tcb.2025.05.005 · Cited by 4
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Català-Castro, F., Bonilla-Quintana, M., Sanfeliu-Cerdán, N., Rangamani, P., & Krieg, M. (2025) · Nature Physics · doi:10.1038/s41567-025-03037-x · Cited by 4
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Muncie, J. M., & Weaver, V. M. (2021) · Cell stem cell · doi:10.1016/j.stem.2021.01.008 · Cited by 4
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Shrestha, A., Pinaud, F. F., & Haselwandter, C. A. (2021) · Physical review. E · doi:10.1103/physreve.104.l022401 · Cited by 4
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Okada, S., Fukai, Y., Yoshimoto, F., & Saitoh, H. (2020) · Biotechnology Letters · doi:10.1007/s10529-020-02848-7 · Cited by 4
Varadarajan, S., Stephenson, R. E., Misterovich, E. R., Wu, J. L., Erofeev, I. S., Goryachev, A. B., & Miller, A. L. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.05.18.444663 · Cited by 5
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Su, R., Wang, S., McDargh, Z. A., & O’Shaughnessy, B. (2023) · Biophysical Journal · doi:10.1016/j.bpj.2023.08.021 · Cited by 3
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Jacobson, K., & Kapustina, M. (2019) · Biophysical Journal · doi:10.1016/j.bpj.2019.07.049 · Cited by 3
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Wang, X., Li, N., Zhang, Z., Qin, K., Zhang, H., Shao, S., & Liu, B. (2023) · Biology · doi:10.3390/biology12060889 · Cited by 3
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Alimohamadi, H., Vasan, R., Hassinger, J., Stachowiak, J. C., & Rangamani, P. (2017) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/157313 · Cited by 6
Osmani, N., Follain, G., García-León, M. J., Lefèbvre, O., Harlepp, S., & Goetz, J. G. (2018) · SSRN Electronic Journal · doi:10.2139/ssrn.3272239 · Cited by 3
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Meo, D. D., Kundu, T., Ravindran, P., Shah, B., & Püschel, A. W. (2024) · Life Science Alliance · doi:10.26508/lsa.202302383 · Cited by 2
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Srinivasan, V., Wang, W., & Camley, B. A. (2026) · Physical review. E · doi:10.1103/z9xd-xbw5 · Cited by 1
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Ye, M., Li, X., Huang, L., Mei, X., Yu, H., Cao, K., Chen, F., & Zhao, Y. (2025) · Journal of the American Chemical Society · doi:10.1021/jacs.5c16545 · Cited by 2
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Liu, X., Wang, Y., Lin, L., Liu, N., Yang, Z., Wang, P., Yan, X., Guo, J., DongDong, J. I. N., & Ma, X. (2026) · Nature Communications · doi:10.1038/s41467-026-70052-8 · Cited by 2
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Locarno, M., Dong, Q., Post, M., Meng, X., Glessi, C., Hettema, N. M., Brandsma, N., Blokhuizen, S., Garcia, A. C., Ganapathy, S., et al. (2026) · Advanced Materials · doi:10.1002/adma.202501944 · Cited by 2
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Kay, A. R., & Aminzare, Z. (2025) · doi:10.63204/15102.4 · Cited by 2
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Sakuma, Y., Yamamoto, K., Ichihara, S., Kawakatsu, T., Haga, K., Imai, M., & Kimura, A. (2025) · Biophysical Journal · doi:10.1016/j.bpj.2025.09.005 · Cited by 2
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Offermanns, S., Wang, S., Shi, Y. X., Möller, T., Stegmeyer, R. I., Strilić, B., Xu, L., Yuan, Z., Wettschureck, N., & Vestweber, D. (2021) · Research Square · doi:10.21203/rs.3.rs-208666/v1 · Cited by 2
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Lachuer, H., Le, L., Lévêque‐Fort, S., Goud, B., & Schauer, K. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.04.22.489160 · Cited by 2
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Hsu, Y.-Y., Irizarry, A. M. R., Fu, J., & Liu, A. P. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.10.04.510821 · Cited by 2
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Brosseau, C. (2023) · Studies in mechanobiology, tissue engineering and biomaterials · doi:10.1007/978-3-031-37981-9_2 · Cited by 2
Javed, A., Stubb, A., Villeneuve, C., Peters, F., Rübsam, M., Niessen, C. M., Biggs, L. C., & Wickström, S. A. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.11.20.624378 · Cited by 2
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Henze, E., Burkhardt, R. N., Fox, B. W., Schwertfeger, T. J., Gelsleichter, E., Michalski, K., Kramer, L., Lenfest, M., Boesch, J. M., Lin, H., et al. (2025) · doi:10.63204/10771.3 · Cited by 2
Ramirez‐Diaz, D. A., Yin, L., Albanesi, D., Zheng, J., de Mendoza, D., & Garner, E. C. (2025) · eLife · doi:10.7554/elife.107679 · Cited by 2
Bocu, R. (2024) · Biosensors · doi:10.3390/bios14080380 · Cited by 1
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Goodband, R. J., & Staykova, M. (2025) · Soft Matter · doi:10.1039/d4sm01410c · Cited by 1
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Sahu, A. (2025) · Journal of Fluid Mechanics · doi:10.1017/jfm.2025.10553 · Cited by 1
Ghosh, T., Majhi, A., Kundu, A., Banerjee, A., & Sinha, B. (2026) · Cell Reports Physical Science · doi:10.1016/j.xcrp.2025.103046 · Cited by 1
Pan, X., Si, H., Yuan, S., Li, R., Liao, G., Wang, W., Zhang, J., Song, J., Chen, S., Liao, S., et al. (2026) · Pesticide Biochemistry and Physiology · doi:10.1016/j.pestbp.2026.107027 · Cited by 1
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Witte, K., Luo, J., Walker, M., Cantini, M., Seib, F. P., & Salmerón‐Sánchez, M. (2021) · Royal Society of Chemistry eBooks · doi:10.1039/9781839161124-00301 · Cited by 1
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Tsujita, K., & Itoh, T. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-89911-6.00005-4 · Cited by 1
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Sukharev, S., & Anishkin, A. (2023) · Биологические мембраны Журнал мембранной и клеточной биологии · doi:10.31857/s0233475523010103 · Cited by 1
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Baruah, N., Midya, J., Gompper, G., Dasanna, A. K., & Auth, T. (2025) · Biophysical Journal · doi:10.1016/j.bpj.2025.01.012 · Cited by 1
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Quintanilla, M. A., Hammer, J. A., & Beach, J. R. (2019) · F1000Research · doi:10.12688/f1000research.18856.1 · Cited by 1
A quantitative model for the caveolae under cell membrane stretch
Zhang, M., & Chen, A. (2020) · Biomechanics and Modeling in Mechanobiology · doi:10.1007/s10237-020-01362-z · Cited by 1
Cytomembrane visualization using Stokes parameter confocal microscopy
Wang, J., He, Y., Wu, Y., Tang, P., Wang, Y., & Tang, Z. (2021) · Applied Optics · doi:10.1364/ao.420892 · Cited by 1
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Metadata
- Authors
- Shi, Z., Graber, Z. T., Baumgart, T., Stone, H. A., & Cohen, A. E.
- Affiliations
- Howard Hughes Medical Institute (US)
- University of Pennsylvania (US)
- Princeton University (US)
- Corresponding author
- Cohen, Adam E.
- Venue
- Cell
- Publisher
- Elsevier BV
- Published
- 2018-12
- Volume
- 175
- Issue
- 7
- Pages
- 1769-1779.e13
- ISSN
- 0092-8674 (ISSN-L)
- PMC
- PMC6541487
- OpenAlex
- W2795033146
- Cited by
- 355
- References
- 95
- Citations by year
- 2026: 32 · 2025: 48 · 2024: 43 · 2023: 41 · 2022: 56 · 2021: 38 · 2020: 49 · 2019: 41 · 2018: 6
- FWCI
- 18.56
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Cell (publishedVersion)
- bioRxiv (Cold Spring Harbor Laboratory) (acceptedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- Gordon and Betty Moore Foundation
- Howard Hughes Medical Institute
- NIH (R01 GM 09755, U54CA193417)
- NSF (CBET-1509347, DMS 1614907)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Cellular Mechanics and Interactions
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Lipid Membrane Structure and Behavior
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Cellular transport and secretion
- Keywords
- membrane tension, cell membrane mechanics, mechanosensitive ion channels, vesicle fusion, endothelial cells, HeLa cells, intracellular signaling
- MeSH terms
- Animals, Cell Membrane, Cytoskeleton, Dogs, HeLa Cells, Humans, Ion Channels, Models, Biological, Signal Transduction, NIH 3T3 Cells, Mice, Rats, Madin Darby Canine Kidney Cells
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