A Quantitative Proteome Map of the Human Body

Jiang, Lihua, Wang, Meng, Lin, Shin, Jian, Ruiqi, Li, Xiao, Chan, Joanne, Dong, Guanlan, Fang, Huaying, Robinson, Aaron E., Aguet, François, Anand, Shankara, Ardlie, Kristin G., Gabriel, Stacey, Getz, Gad, Graubert, Aaron, Hadley, Kane, Handsaker, Robert E., Huang, Katherine H., Kashin, Seva, MacArthur, Daniel G., Meier, Samuel R., Nedzel, Jared L., Nguyen, Duyen Y., Segrè, Ayellet V., Todres, Ellen, Balliu, Brunilda, Barbeira, Alvaro N., Battle, Alexis, Bonazzola, Rodrigo, Brown, Andrew, Brown, Christopher D., Castel, Stephane E., Conrad, Don, Cotter, Daniel J., Cox, Nancy, Das, Sayantan, de Goede, Olivia M., Dermitzakis, Emmanouil T., Engelhardt, Barbara E., Eskin, Eleazar, Eulalio, Tiffany Y., Ferraro, Nicole M., Flynn, Elise, Fresard, Laure, Gamazon, Eric R., Garrido-Martín, Diego, Gay, Nicole R., Guigó, Roderic, Hamel, Andrew R., He, Yuan, Hoffman, Paul J., Hormozdiari, Farhad, Hou, Lei, Im, Hae Kyung, Jo, Brian, Kasela, Silva, Kellis, Manolis, Kim-Hellmuth, Sarah, Kwong, Alan, Lappalainen, Tuuli, Li, Xin, Liang, Yanyu, Mangul, Serghei, Mohammadi, Pejman, Montgomery, Stephen B., Muñoz-Aguirre, Manuel, Nachun, Daniel C., Nobel, Andrew B., Oliva, Meritxell, Park, YoSon, Park, Yongjin, Parsana, Princy, Reverter, Ferran, Rouhana, John M., Sabatti, Chiara, Saha, Ashis, Skol, Andrew D., Stephens, Matthew, Stranger, Barbara E., Strober, Benjamin J., Teran, Nicole A., Viñuela, Ana, Wang, Gao, Wen, Xiaoquan, Wright, Fred, Wucher, Valentin, Zou, Yuxin, Ferreira, Pedro G., Li, Gen, Melé, Marta, Yeger-Lotem, Esti, Barcus, Mary E., Bradbury, Debra, Krubit, Tanya, McLean, Jeffrey A., Qi, Liqun, Robinson, Karna, Roche, Nancy V., Smith, Anna M., Sobin, Leslie, Tabor, David E., Undale, Anita, Bridge, Jason, Brigham, Lori E., Foster, Barbara A., Gillard, Bryan M., Hasz, Richard, Hunter, Marcus, Johns, Christopher, Johnson, Mark, Karasik, Ellen, Kopen, Gene, Leinweber, William F., McDonald, Alisa, Moser, Michael T., Myer, Kevin, Ramsey, Kimberley D., Roe, Brian, Shad, Saboor, Thomas, Jeffrey A., Walters, Gary, Washington, Michael, Wheeler, Joseph, Jewell, Scott D., Rohrer, Daniel C., Valley, Dana R., Davis, David A., Mash, Deborah C., Branton, Philip A., Barker, Laura K., Gardiner, Heather M., Mosavel, Maghboeba, Siminoff, Laura A., Flicek, Paul, Haeussler, Maximilian, Juettemann, Thomas, Kent, W. James, Lee, Christopher M., Powell, Conner C., Rosenbloom, Kate R., Ruffier, Magali, Sheppard, Dan, Taylor, Kieron, Trevanion, Stephen J., Zerbino, Daniel R., Abell, Nathan S., Akey, Joshua, Chen, Lin, Demanelis, Kathryn, Doherty, Jennifer A., Feinberg, Andrew P., Hansen, Kasper D., Hickey, Peter F., Jasmine, Farzana, Kaul, Rajinder, Kibriya, Muhammad G., Li, Jin Billy, Li, Qin, Linder, Sandra E., Pierce, Brandon L., Rizzardi, Lindsay F., Smith, Kevin S., Stamatoyannopoulos, John, Tang, Hua, Carithers, Latarsha J., Guan, Ping, Koester, Susan E., Little, A. Roger, Moore, Helen M., Nierras, Concepcion R., Rao, Abhi K., Vaught, Jimmie B., Volpi, Simona, Snyder, Michael P.·2020·Cell

Cited by (460)

Items 401–460 of 460

  1. Self-consistent signal transduction analysis for modeling context-specific signaling cascades and perturbations
    John A. Cole · 2024 · npj Systems Biology and Applications
  2. Pan-cancer N -glycoproteomic atlas of patient-derived xenografts uncovers FAT2 as a therapeutic target for head and neck cancers
    Meinusha Govindarajan, Salvador Mejia‐Guerrero, Shawn C. Chafe, Shahbaz Khan, Wei Shi, Matthew Waas, Amanda Khoo, Lydia Liu, Vladimir Ignatchenko, Simona Principe et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  3. Uterine Tumors and the Environment
    Shuhong Yang, Lyda Yuliana Parra-Forero, Adriana R Andrus, Coba N Sexton, Dong Kuang, Romana A. Nowak · 2025 · Elsevier eBooks
  4. Intergenerational control of ribosomes under dietary restriction
    Sigma Pradhan, Klement Stojanovski, Joel Tuomaala, Nicholas Stroustrup, Benjamin D. Towbin · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  5. Serendipitous and Systematic Chemoproteomic Discovery of MBLAC2, HINT1, and NME1-4 Inhibitors from Histone Deacetylase-Targeting Pharmacophores
    Severin Lechner, Shuyao Sha, Jigar P. Sethiya, Patrycja Szczupak, Rafał Dolot, Santosh Kumar Lomada, Amirhossein Sakhteman, Johanna Tüshaus, Polina Prokofeva, Michael I. Krauss et al. · 2025 · ACS Chemical Biology
  6. Charting the Circulating Proteome in ME/CFS: Cross System Profiling and Mechanistic Insights
    August Hoel, Fredrik Hoel, Sissel E. Dyrstad, Henrique Chapola, Ingrid G. Rekeland, Kristin Risa, Kine Alme, Kari Sørland, Karl Albert Brokstad, Hans‐Peter Marti et al. · 2025 · medRxiv
  7. Advancing Pediatric Drug Safety: The Potential of Physiologically Based Pharmacokinetic Modeling
    Krishna Yadav · 2025 · Drug Metabolism and Bioanalysis Letters
  8. MLMarker: a machine learning framework for tissue inference and biomarker discovery
    Tine Claeys, Sam van Puyenbroeck, Kris Gevaert, Lennart Martens · 2026 · Genome biology
  9. The Challenges and Opportunities of Higher Education in Romania During the COVID-19 Pandemic: An Analysis of Teachers' and Students' Perceptions of Online Education
    Diana IVANA · 2025 · Review of International Comparative Management
  10. Deepening imaging-based spatial proteomics at high spatial resolution through controlled tissue resizing and in-situ bottom-up mass spectrometry
    Kunyue Deng, Lingpeng Zhan, Yi Li, Jingpeng Zhang, Mingchuan Tang, Tianyi Chang, Gang Ji, Xinyang Shao, Xiang Xu, Xiaoyun Wei et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  11. ProMix: Enhancing Protein Quantification through Experimental Design and Statistical Normalization
    Huaying Fang, Mei‐Chiung Shih, Lihua Jiang, Felipe da Veiga Leprevost, Ruiqi Jian, Joanne Chan, Alexey I. Nesvizhskii, Michael P. Snyder, Hua Tang · 2025 · Journal of Proteome Research
  12. Proximity Extension Assay identifies new targets of grey matter pathology in multiple sclerosis
    Hannah van der Stok, Loet Coenen, M. Weil, J Mollon, C. Klein, R. Müller, Helga E. de Vries, Merel Rijnsburger · 2025 · Multiple Sclerosis and Related Disorders
  13. Molecular architecture of language‐related cortical areas revealed by integrative proteomic and connectome analyses
    Jinsong Wu, Zixian Wang, Fengjiao Li, Shuolei Bu, Lianglong Sun, Zheng Chen, Zhixin Bai, Luhao Yang, Fangyuan Gong, Jiali Chen et al. · 2025 · Clinical and Translational Medicine
  14. Surface proteomics reveals arginine metabolism as a vulnerability in high grade serous ovarian cancer
    Meinusha Govindarajan, Matthew Waas, Salvador Meija-Guerrero, Brian Lin, Tianyi Ling, Ximing Li, Vladimir Ignatchenko, Anastasia N. Tikhonova, Courtney L. Jones, Laurie Ailles et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  15. Tau Enhances Aggregation of S100A9 Protein and Further Association of Its Fibrils
    Lukas Krasauskas, Dominykas Veiveris, Mantas Žiaunys, Darius Šulskis, Andrius Sakalauskas, Vytautas Smirnovas · 2025 · International Journal of Molecular Sciences
  16. Reproducible autosomal gene expression changes with loss of typical X and Y complement across tumor types
    S. Plaisier, Robert Phavong, Mason Farmwald, Mariah Lee, Teagen Allen, M. Swamy, Ilsa Rodriguez, MacKenzie Wells, Nadia Phaneuf, S. Massey et al. · 2025 · bioRxiv
  17. MCUR1–CCDC90B complex is a conserved mitochondrial scaffold regulating metabolic homeostasis
    J Verissimo Ferreira, Jennifer Wettmarshausen, Valerie Goh, K Lagerborg, J Watrous, MS Feng, H Delgado de la Herran, S Walia, Y Cheng, A Leimpek et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  18. A spatially resolved human brain proteome atlas for decoding brain function and disease
    Qi Xiao, Yuting Xie, Meng Luo, Hui Yang, Zhengyi Yang, Ming Chen, Nan Wang, Zhaoxing Li, Jinlong Gao, Jing Yu et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  19. Proteomic insights into the macaque insular parcellation based on structural connectivity gradients.
    Xinyi Liu, Long Cao, Zongchang Du, Yue Cui, K. Saleem, Yuan-Chao Zhang, Yu-Heng Lu, Baogui B Zhang, Yanyan Y Liu, Xiaoxiao Hou et al. · 2025 · Cerebral Cortex
  20. Information Network Flux interprets the importance of regulatory circuits in the protein and gene spaces
    Boxin Xue, Ran Jiang, Yue Xue, Hong Zhang, Sirui Liu, Yi Qin Gao · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  21. Integrated analysis of post-transcriptional regulations reveals insights into acute myeloid leukemia
    Elissa Khadra, Zoaila Iqbal, Morgane Le Gall, Guilhem Clary, Françoise Levavasseur, Zubaidan Tuerdi, Charles Dussiau, David Rombaut, Marie Templé, Chloé Friedrich et al. · 2025 · Communications Biology
  22. Additional file 8 of Using protein-per-mRNA differences among human tissues in codon optimization
    Hernandez-Alias, Xavier, Hannah Benisty, Leandro Radusky, Serrano, Luis, Martin H. Schaefer · 2023 · Figshare
  23. Additional file 5 of Organelle resolved proteomics uncovers PLA2R1 as a novel cell surface marker required for chordoma growth
    Shahbaz Khan, Jeffrey Zuccato, Vladimir Ignatchenko, Singh, Olivia, Meinusha Govindarajan, Matthew Waas, Salvador Mejia‐Guerrero, Gao, Andrew, Zadeh, Gelareh, Thomas Kislinger · 2024 · Figshare
  24. Additional file 2 of Organelle resolved proteomics uncovers PLA2R1 as a novel cell surface marker required for chordoma growth
    Shahbaz Khan, Jeffrey Zuccato, Vladimir Ignatchenko, Singh, Olivia, Meinusha Govindarajan, Matthew Waas, Salvador Mejia‐Guerrero, Gao, Andrew, Zadeh, Gelareh, Thomas Kislinger · 2024 · Figshare
  25. Additional file 1 of Organelle resolved proteomics uncovers PLA2R1 as a novel cell surface marker required for chordoma growth
    Shahbaz Khan, Jeffrey Zuccato, Vladimir Ignatchenko, Singh, Olivia, Meinusha Govindarajan, Matthew Waas, Salvador Mejia‐Guerrero, Gao, Andrew, Zadeh, Gelareh, Thomas Kislinger · 2024 · Figshare
  26. Additional file 3 of Organelle resolved proteomics uncovers PLA2R1 as a novel cell surface marker required for chordoma growth
    Shahbaz Khan, Jeffrey Zuccato, Vladimir Ignatchenko, Singh, Olivia, Meinusha Govindarajan, Matthew Waas, Salvador Mejia‐Guerrero, Gao, Andrew, Zadeh, Gelareh, Thomas Kislinger · 2024 · Figshare
  27. Additional file 4 of Organelle resolved proteomics uncovers PLA2R1 as a novel cell surface marker required for chordoma growth
    Shahbaz Khan, Jeffrey Zuccato, Vladimir Ignatchenko, Singh, Olivia, Meinusha Govindarajan, Matthew Waas, Salvador Mejia‐Guerrero, Gao, Andrew, Zadeh, Gelareh, Thomas Kislinger · 2024 · Figshare
  28. Additional file 1 of Using protein-per-mRNA differences among human tissues in codon optimization
    Xavier Hernandez‐Alias, Hannah Benisty, Leandro Radusky, Serrano, Luis, Martin H. Schaefer · 2023 · Figshare
  29. Exploring QRICH2 as a potential male contraceptive target
    Amandine Delnatte, Messaline Inglese, Jérôme Delroisse, Denis Nonclercq, Annica Frau, Ruddy Wattiez, Baptiste Leroy, Vanessa Arcolia, Jean-François Simon, Thibault Masai et al. · 2026 · Reproduction
  30. Pan-cancer N-glycoproteomic atlas of patient-derived xenografts uncovers FAT2 as an actionable surface target
    Meinusha Govindarajan, Salvador Mejia‐Guerrero, Shawn C. Chafe, Shahbaz Khan, Wei Shi, Matthew Waas, Martín A. Rossotti, Amanda Khoo, Lydia Liu, Vladimir Ignatchenko et al. · 2026 · Cell Reports Medicine
  31. Mitochondrial ribosome content as a proxy for respiration
    Francis Mairet · 2026 · Biology Letters
  32. Large-Scale Identification of Novel Protein Biomarkers and Therapeutic Targets in Heart and Brain Disease
    Chao Jun Wu, Dantong Li, Sumeet A. Khetarpal, Zixun Yuan, Shengyuan Huang, Justin Ralph Baldovino Guerra, Chunyu Li, Qiulian Zhou, Meixi Quan, Jiaqi He et al. · 2026 · medRxiv
  33. Multi‐Tissue Omics Analysis Uncovers Translational Regulation Underlying Complex Traits in Pigs
    Chao Wang, Yuanyuan Zhang, Choulin Chen, Xiaoxian Xu, Shenghua Qin, Junyan Qi, Yongzhou Bao, Huiming Li, Ruipu Chen, Weigang Zheng et al. · 2026 · Advanced Science
  34. Proteomic atlas of human peritoneal tissue
    Qiangmin Zhang, Christopher Sherry, Xi Peng, Yunxiang Fu, Nujsaubnusi Cassandra Vue, Rosie Blodgett, Hyun Young Park, Erin E. Grayhack, Neda Dadgar, Xue Li et al. · 2026 · Scientific Reports
  35. From the Dark Genome to Immunotherapy Targets: Artificial Intelligence Enables the Identification of Noncanonical Neoantigens
    Juan Xu, Yangyang Cai, J Q Guo, Dezhong Lv, Yingying Ma, Wenjun Mao, Qinghua Jiang, Yongsheng Li · 2026 · Research
  36. Direct Cardiac Reprogramming in the Omics Era: Advances, Mechanisms, and Applications
    Chelsea Li, Li Qian · 2026 · Cellular Reprogramming
  37. Blood Biochemical Responses to Acute Exercise: Findings from the Molecular Transducers of Physical Activity Consortium (MoTrPAC)
    Jeremy Robbins, Daniel H. Katz, Gina M. Many, Prashant Rao, Gregory R. Smith, Gaurav Tiwari, Christopher A. Jin, Guillaume Spielmann, Samuel Montalvo, Gayatri R. Iyer et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  38. A comprehensive proteome and phosphoproteome atlas across nine organs of the Chinese hamster
    Luyao Zhang, Tao Ding, Wanjun Peng, Jie Kong, Xiaoyue Tang, Jiyu Xu, Qiaochu Wang, Zhiyi Zhang, Chunmei Shi, Yizhuo Tian et al. · 2026 · Animal Models and Experimental Medicine
  39. G/C-ending and synonymous codon bias define functional translational programs that shape human tissue and cancer proteomes
    Sherif Rashad, Kuniyasu Niizuma · 2026 · NAR Genomics and Bioinformatics
  40. Modélisation de l’épithélium bronchique par les cellules souches pluripotentes induites humaines dans la bronchopneumopathie chronique obstructive (BPCO)
    Mathieu Fieldès · 2020 · theses.fr (ABES)
  41. Étude de la biodisponibilité digestive et métabolique des protéines alimentaires après bypass gastrique
    Soukaïna Benhaddou · 2024 · theses.fr (ABES)
  42. Species-wide survey of transcript and protein abundance variation in yeast
    Élie Teyssonnière · 2023 · theses.fr (ABES)
  43. PRKD3 Overexpression May Improve Survival and Suppresses Proliferation in Colorectal Cancer
    Bin Zhang, Chen Min Chang, Jingli Chen, Y R Cao, Yu Chang, Lele Liu, Wensheng Li, Guorong Wang · 2026 · Cancer Reports
  44. Brain Proteomic Responses to Glucocorticoids and Their Relationship With Transcriptome: A Systematic Meta‐Analysis
    Grzegorz Roman Juszczak · 2026 · The FASEB Journal
  45. P-Rex Rac-GEFs
    Heidi C. E. Welch · 2026 · Cellular Signalling
  46. ATP-Related Proteins Were Associated with Hürthle Cell Carcinomas Identified by Bioinformatic Analysis and Immunohistochemistry
    Jiaxi Wang, Yinxin Li, Mingzhu YAN, Hanqing LIU, C Chen · 2026 · Wuhan University Journal of Natural Sciences
  47. Plasma Proteomics Reveals Divergent Sex-Specific Senescence and Bone Biology Signatures across Neurodegenerative Diseases
    Siddharth Kaipa, Ting Zhai, Sai Rama Krishna Meka, Patricia Morán Losada, Zihuai He, Divya Channappa, Hamilton Se‐Hwee Oh, Jarod Rutledge, Michael Zeineh, Anthony Agudelo et al. · 2026 · SSRN Electronic Journal
  48. An integrated proteogenomic investigation of the human liver uncovers molecular drivers of steatotic liver disease
    Émilie Gobeil, Jérôme Bourgault, Malie Enault, Valérie Côté, Patricia L. Mitchell, Louis‐Jacques Ruel, Arnaud S. Girard, Marie‐Claude Vohl, Benoît J. Arsenault · 2026 · medRxiv
  49. Identifying and investigating emergent behaviour in neural systems
    Kyle C. A. Wedgwood, Patrick McGivern, Alexander R. Harris · 2026 · Frontiers in Neuroscience
  50. Postpartum Uterine Diseases in Dairy Cattle: Integrating Microbiology, Immunology, and Reproductive Physiology
    Ramanathan K. Kasimanickam, Priunka Bhowmik, Zhihua Jiang · 2026 · Microorganisms
  51. Genome-wide pQTL mapping in human skin identifies specific genetic regulators and mechanistic links to skin disorders
    Yuanqiang Sun, Wenchao Li, Zhenzhen Wang, Yongliang Yang, Ziyang Zhang, Gongqi Yu, Chuan Wang, Xu Sang, Yingjie Lin, Guangliang Zhang et al. · 2026 · Nature Communications
  52. Unlocking the Circulating Proteome: Toward Clinical Translation
    Sara Ahadi, Haris Babačić, Lee S. Cantrell, Daniel Hornburg, Johannes Müller, Laura F. Dagley, Ida Chiara Guerrera, Vincent Albrecht, Fredrik Edfors, Xiaobo Yu et al. · 2026 · Journal of Proteome Research
  53. A novel tumor necrosis factor-alpha-targeting protein degrader for the treatment of acute liver failure
    Junjie He, Xuanyi Li, Wen Hu, Yuting Zhang, Zhuochao Zhang, Siyu Zhao, Muyang He, Jing Wang, He Xiao, Xinying Li et al. · 2026 · International Journal of Biological Macromolecules
  54. NAE1-Dependent Protein Neddylation Preserves Endothelial Identity and Vascular Integrity
    Rachelle Nelson Zoni, Fatema Yeasmin Tanni, Chang Min Lee, Xiao Cheng, Jiyao Zhu, Vijaya B Baki, Md Sadikul Islam, Jie Li, Huabo Su, Xinghui Sun · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  55. HONU: A Multicenter, Prospective, Observational Study of the Progression of Intermediate Age-Related Macular Degeneration
    Robyn H. Guymer, Zhichao Wu, Simon S. Gao, Miao Zhang, Verena Steffen, Chen Chen, Jiameng Zhang, Katie M. Litts, Michael Chang, Justin Elstrott et al. · 2026 · Ophthalmology Science
  56. Ashwin and FAM98 paralogs define nuclear and cytoplasmic RNA ligase complexes for tRNA biogenesis
    Moshe Leitner, Marius Moser, Nathan Raynaud, Moritz M. Pfleiderer, Martin Jínek, Javier Martı̂nez · 2026 · Nature Communications
  57. RBM protein family: Focusing on the occurrence, progression and treatment of cancer
    Huhu Zhang, Wenxin Zheng, Lingxi Li, Chenhui Geng, Yuxiang Wang, Jianyu Zhang, 孙玉兰, Xuanyu Zhang, Bing Li · 2026 · Medical Oncology
  58. Mitochondrial and metabolic plasticity distinguish stem cells from progenitors in the male germline
    Katerina B. Damyanova, Joshua J Fisher, Siddharth Acharya, Brett Nixon, Tessa Lord · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  59. Combining RNA-seq and proteomics boosts sensitivity to detect differentially expressed genes by rpMeta
    Xijun Zhang, Joseph P. LaMorte, Robert L. Kortum, Craig D. Shriver, Clifton L. Dalgard, Matthew D. Wilkerson · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  60. FAIRsharing record for: FerrDb V2
    FAIRsharing Team, , · 2023 · FAIRsharing.org