Eskin, Eleazar

The GTEx Consortium atlas of genetic regulatory effects across human tissues

The GTEx Consortium, Aguet, F., Anand, S., Ardlie, K. G., Gabriel, S., Getz, G. A., Graubert, A., Hadley, K., Handsaker, R. E., Huang, K. H., et al. (2020) · Science

Genetic Associations and EpidemiologyRNA Research and Splicing

Cited by 5,547

Variance component model to account for sample structure in genome-wide association studies

Kang, H. M., Sul, J. H., Service, S. K., Zaitlen, N. A., Kong, S.-Y., Freimer, N. B., Sabatti, C., & Eskin, E. (2010) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 2,817

Mouse genomic variation and its effect on phenotypes and gene regulation.

Keane, T. M., Goodstadt, L., Danecek, P., White, M. A., Wong, K., Yalcin, B., Heger, A., Agam, A., Slater, G., Goodson, M., et al. (2011) · Nature

Genetic Mapping and Diversity in Plants and AnimalsGenetic and phenotypic traits in livestock

Cited by 1,580

Assessing computational tools for the discovery of transcription factor binding sites

Tompa, M., Li, N., Bailey, T. L., Church, G. M., De Moor, B., Eskin, E., Favorov, A. V., Frith, M. C., Fu, Y., Kent, W. J., et al. (2005) · Nature Biotechnology

Genomics and Chromatin DynamicsGenomics and Phylogenetic Studies

Cited by 1,268

Colocalization of GWAS and eQTL Signals Detects Target Genes

Hormozdiari, F., van de Bunt, M., Segrè, A. V., Li, X., Joo, J. W. J., Bilow, M., Sul, J. H., Sankararaman, S., Pasaniuc, B., & Eskin, E. (2016) · The American Journal of Human Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 697

A Geometric Framework for Unsupervised Anomaly Detection: Detecting Intrusions in Unlabeled Data

Eskin, E., Arnold, A., Prerau, M., Portnoy, L., & Stolfo, S. (2002) · Advances in Information Security

Network Security and Intrusion DetectionAnomaly Detection Techniques and Applications

Cited by 683

Random-Effects Model Aimed at Discovering Associations in Meta-Analysis of Genome-wide Association Studies

Han, B., & Eskin, E. (2011) · The American Journal of Human Genetics

Genetic Associations and EpidemiologyMeta-analysis and systematic reviews

Cited by 680

Comparative analysis of proteome and transcriptome variation in mouse

Ghazalpour, A., Bennett, B., Petyuk, V. A., Orozco, L., Hagopian, R., Mungrue, I. N., Farber, C. R., Sinsheimer, J., Kang, H. M., Furlotte, N., et al. (2011) · PLoS Genetics

Advanced Proteomics Techniques and ApplicationsBioinformatics and Genomic Networks

Cited by 624

Chromosome conformation elucidates regulatory relationships in developing human brain

Won, H., de la Torre-Ubieta, L., Stein, J. L., Parikshak, N. N., Huang, J., Opland, C. K., Gandal, M. J., Sutton, G. J., Hormozdiari, F., Lu, D., et al. (2016) · Nature

Genomics and Chromatin DynamicsGenomic variations and chromosomal abnormalities

Cited by 584

Genetic Control of Obesity and Gut Microbiota Composition in Response to High-Fat, High-Sucrose Diet in Mice

Parks, B. W., Nam, E., Org, E., Kostem, E., Norheim, F., Hui, S. T., Pan, C., Civelek, M., Rau, C. D., Bennett, B. J., et al. (2013) · Cell Metabolism

Gut microbiota and healthNutrition, Genetics, and Disease

Cited by 544

Determinants of telomere length across human tissues

Demanelis, K., Jasmine, F., Chen, L. S., Chernoff, M., Tong, L., Delgado, D., Zhang, C., Shinkle, J., Sabarinathan, M., Lin, H., et al. (2020) · Science

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 515

Identifying Causal Variants at Loci with Multiple Signals of Association

Hormozdiari, F., Kostem, E., Kang, E. Y., Pasaniuc, B., & Eskin, E. (2014) · Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 465

A Quantitative Proteome Map of the Human Body

Jiang, L., Wang, M., Lin, S., Jian, R., Li, X., Chan, J., Dong, G., Fang, H., Robinson, A. E., Aguet, F., et al. (2020) · Cell

Advanced Proteomics Techniques and ApplicationsBioinformatics and Genomic Networks

Cited by 458

Using an atlas of gene regulation across 44 human tissues to inform complex disease- and trait-associated variation

GTEx Consortium, Gamazon, E. R., Segrè, A. V., van de Bunt, M., Wen, X., Xi, H. S., Hormozdiari, F., Ongen, H., Konkashbaev, A., Derks, E. M., et al. (2018) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 412

Genetic and environmental control of host-gut microbiota interactions

Org, E., Parks, B. W., Joo, J. W. J., Emert, B., Schwartzman, W., Kang, E. Y., Mehrabian, M., Pan, C., Knight, R., Gunsalus, R., et al. (2015) · Genome Research

Gut microbiota and healthNutrition, Genetics, and Disease

Cited by 381

Genome-wide association study of bipolar disorder in European American and African American individuals

Smith, E. N., Bloss, C. S., Badner, J. A., Barrett, T., Belmonte, P. L., Berrettini, W., Byerley, W., Coryell, W., Craig, D., Edenberg, H. J., et al. (2009) · Molecular Psychiatry

Bipolar Disorder and TreatmentGenetic Associations and Epidemiology

Cited by 363

A Comparison of Phasing Algorithms for Trios and Unrelated Individuals

Marchini, J., Cutler, D., Patterson, N., Stephens, M., Eskin, E., Halperin, E., Lin, S., Qin, Z. S., Munro, H. M., Abecasis, G. R., et al. (2006) · The American Journal of Human Genetics

Genetic Associations and EpidemiologyForensic and Genetic Research

Cited by 341

Genome-wide analysis highlights contribution of immune system pathways to the genetic architecture of asthma

Han, Y., Jia, Q., Jahani, P. S., Hurrell, B. P., Pan, C., Huang, P., Gukasyan, J., Woodward, N. C., Eskin, E., Gilliland, F. D., et al. (2020) · Nature Communications

Asthma and respiratory diseasesGenetic Associations and Epidemiology

Cited by 222

The Hybrid Mouse Diversity Panel: a resource for systems genetics analyses of metabolic and cardiovascular traits

Lusis, A. J., Seldin, M. M., Allayee, H., Bennett, B. J., Civelek, M., Davis, R. C., Eskin, E., Farber, C. R., Hui, S., Mehrabian, M., et al. (2016) · Journal of Lipid Research

Genetic Mapping and Diversity in Plants and AnimalsGenetic Associations and Epidemiology

Cited by 158

Genome-wide analysis reveals novel genes influencing temporal lobe structure with relevance to neurodegeneration in Alzheimer’s disease

Stein, J. L., Hua, X., Morra, J. H., Lee, S., Hibar, D. P., Ho, A. J., Leow, A. D., Toga, A. W., Sul, J. H., Kang, H. M., et al. (2010) · NeuroImage

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 145

EFFICIENT RECONSTRUCTION OF HAPLOTYPE STRUCTURE VIA PERFECT PHYLOGENY

ESKIN, E., HALPERIN, E., & KARP, R. M. (2003) · Journal of Bioinformatics and Computational Biology

Genomics and Phylogenetic StudiesGenetic Associations and Epidemiology

Cited by 131

Fine mapping in 94 inbred mouse strains using a high-density haplotype resource

Kirby, A., Kang, H. M., Wade, C. M., Cotsapas, C., Kostem, E., Han, B., Furlotte, N., Kang, E. Y., Rivas, M., Bogue, M. A., et al. (2010) · Genetics

Genetic Mapping and Diversity in Plants and AnimalsGenetic Associations and Epidemiology

Cited by 102

Challenges and recommendations to improve the installability and archival stability of omics computational tools

Mangul, S., Mosqueiro, T., Abdill, R. J., Duong, D., Mitchell, K., Sarwal, V., Hill, B., Brito, J., Littman, R. J., Statz, B., et al. (2019) · PLOS Biology

Scientific Computing and Data ManagementResearch Data Management Practices

Cited by 90

Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics

Barbeira, A. N., Dickinson, S. P., Bonazzola, R., Zheng, J., Wheeler, H. E., Torres, J. M., Torstenson, E. S., Shah, K. P., Garcia, T., Edwards, T. L., et al. (2018) · Nature Communications

Genetic Associations and EpidemiologyBioinformatics and Genomic Networks

Cited by 69