Akey, Joshua M.

The GTEx Consortium atlas of genetic regulatory effects across human tissues

The GTEx Consortium, Aguet, F., Anand, S., Ardlie, K. G., Gabriel, S., Getz, G. A., Graubert, A., Hadley, K., Handsaker, R. E., Huang, K. H., et al. (2020) · Science

Genetic Associations and EpidemiologyRNA Research and Splicing

Cited by 5,547

The accessible chromatin landscape of the human genome

Thurman, R. E., Rynes, E., Humbert, R., Vierstra, J., Maurano, M. T., Haugen, E., Sheffield, N. C., Stergachis, A. B., Wang, H., Vernot, B., et al. (2012) · Nature

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 2,679

Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations

O’Roak, B. J., Vives, L., Girirajan, S., Karakoc, E., Krumm, N., Coe, B. P., Levy, R., Ko, A., Lee, C., Smith, J. D., et al. (2012) · Nature

Autism Spectrum Disorder ResearchGenetics and Neurodevelopmental Disorders

Cited by 2,165

Evolution and functional impact of rare coding variation from deep sequencing of human exomes

Tennessen, J. A., Bigham, A. W., O’Connor, T. D., Fu, W., Kenny, E. E., Gravel, S., McGee, S., Do, R., Liu, X., Jun, G., et al. (2012) · Science

Genomics and Rare DiseasesGenetic Associations and Epidemiology

Cited by 1,613

Multiplex Targeted Sequencing Identifies Recurrently Mutated Genes in Autism Spectrum Disorders

O’Roak, B. J., Vives, L., Fu, W., Egertson, J. D., Stanaway, I. B., Phelps, I. G., Carvill, G., Kumar, A., Lee, C., Ankenman, K., et al. (2012) · Science

Autism Spectrum Disorder ResearchGenetics and Neurodevelopmental Disorders

Cited by 1,240

Estimating African American Admixture Proportions by Use of Population-Specific Alleles

Parra, E. J., Marcini, A., Akey, J., Martinson, J., Batzer, M. A., Cooper, R., Forrester, T., Allison, D. B., Deka, R., Ferrell, R. E., et al. (1998) · The American Journal of Human Genetics

Forensic and Genetic ResearchRace, Genetics, and Society

Cited by 771

Tracing the peopling of the world through genomics

Nielsen, R., Akey, J. M., Jakobsson, M., Pritchard, J. K., Tishkoff, S., & Willerslev, E. (2017) · Nature

Forensic and Genetic ResearchPleistocene-Era Hominins and Archaeology

Cited by 728

Identifying Signatures of Natural Selection in Tibetan and Andean Populations Using Dense Genome Scan Data

Bigham, A., Bauchet, M., Pinto, D., Mao, X., Akey, J. M., Mei, R., Scherer, S. W., Julian, C. G., Wilson, M. J., López Herráez, D., et al. (2010) · PLoS Genetics

High Altitude and HypoxiaForensic and Genetic Research

Cited by 597

Resurrecting Surviving Neandertal Lineages from Modern Human Genomes

Vernot, B., & Akey, J. M. (2014) · Science

Pleistocene-Era Hominins and ArchaeologyForensic and Genetic Research

Cited by 562

Determinants of telomere length across human tissues

Demanelis, K., Jasmine, F., Chen, L. S., Chernoff, M., Tong, L., Delgado, D., Zhang, C., Shinkle, J., Sabarinathan, M., Lin, H., et al. (2020) · Science

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 515

Excavating Neandertal and Denisovan DNA from the genomes of Melanesian individuals

Vernot, B., Tucci, S., Kelso, J., Schraiber, J. G., Wolf, A. B., Gittelman, R. M., Dannemann, M., Grote, S., McCoy, R. C., Norton, H., et al. (2016) · Science

Pleistocene-Era Hominins and ArchaeologyForensic and Genetic Research

Cited by 459

A Quantitative Proteome Map of the Human Body

Jiang, L., Wang, M., Lin, S., Jian, R., Li, X., Chan, J., Dong, G., Fang, H., Robinson, A. E., Aguet, F., et al. (2020) · Cell

Advanced Proteomics Techniques and ApplicationsBioinformatics and Genomic Networks

Cited by 458

Analysis of Human Sequence Data Reveals Two Pulses of Archaic Denisovan Admixture

Browning, S. R., Browning, B. L., Zhou, Y., Tucci, S., & Akey, J. M. (2018) · Cell

Pleistocene-Era Hominins and ArchaeologyForensic and Genetic Research

Cited by 381

Tracking footprints of artificial selection in the dog genome

Akey, J. M., Ruhe, A. L., Akey, D. T., Wong, A. K., Connelly, C. F., Madeoy, J., Nicholas, T. J., & Neff, M. W. (2010) · Proceedings of the National Academy of Sciences

Genetic and phenotypic traits in livestockHuman-Animal Interaction Studies

Cited by 350

The phenotypic legacy of admixture between modern humans and Neandertals

Simonti, C. N., Vernot, B., Bastarache, L., Bottinger, E., Carrell, D. S., Chisholm, R. L., Crosslin, D. R., Hebbring, S. J., Jarvik, G. P., Kullo, I. J., et al. (2016) · Science

Pleistocene-Era Hominins and ArchaeologyGenetic Associations and Epidemiology

Cited by 330

Identifying and Interpreting Apparent Neanderthal Ancestry in African Individuals

Chen, L., Wolf, A. B., Fu, W., Li, L., & Akey, J. M. (2020) · Cell

Pleistocene-Era Hominins and ArchaeologyForensic and Genetic Research

Cited by 254

A powerful and flexible statistical framework for testing hypotheses of allele-specific gene expression from RNA-seq data

Skelly, D. A., Johansson, M., Madeoy, J., Wakefield, J., & Akey, J. M. (2011) · Genome Research

Genomics and Phylogenetic StudiesRNA Research and Splicing

Cited by 203

Impacts of Neanderthal-Introgressed Sequences on the Landscape of Human Gene Expression

McCoy, R. C., Wakefield, J., & Akey, J. M. (2017) · Cell

Pleistocene-Era Hominins and ArchaeologyGenetic Associations and Epidemiology

Cited by 200

Archaic Hominin Admixture Facilitated Adaptation to Out-of-Africa Environments

Gittelman, R. M., Schraiber, J. G., Vernot, B., Mikacenic, C., Wurfel, M. M., & Akey, J. M. (2016) · Current Biology

Pleistocene-Era Hominins and ArchaeologyForensic and Genetic Research

Cited by 181

Complex History of Admixture between Modern Humans and Neandertals

Vernot, B., & Akey, J. M. (2015) · The American Journal of Human Genetics

Pleistocene-Era Hominins and ArchaeologyForensic and Genetic Research

Cited by 149

Evolutionary history and adaptation of a human pygmy population of Flores Island, Indonesia

Tucci, S., Vohr, S. H., McCoy, R. C., Vernot, B., Robinson, M. R., Barbieri, C., Nelson, B. J., Fu, W., Purnomo, G. A., Sudoyo, H., et al. (2018) · Science

Pleistocene-Era Hominins and ArchaeologyForensic and Genetic Research

Cited by 97

Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics

Barbeira, A. N., Dickinson, S. P., Bonazzola, R., Zheng, J., Wheeler, H. E., Torres, J. M., Torstenson, E. S., Shah, K. P., Garcia, T., Edwards, T. L., et al. (2018) · Nature Communications

Genetic Associations and EpidemiologyBioinformatics and Genomic Networks

Cited by 69

Interaction between the melanocortin-1 receptor andP genes contributes to inter-individual variation in skin pigmentation phenotypes in a Tibetan population

Akey, J. M., Wang, H., Xiong, M., Wu, H., Liu, W., Shriver, M. D., & Jin, L. (2001) · Human Genetics

melanin and skin pigmentationGenetic Associations and Epidemiology

Cited by 67

Human Evolution: Genomic Gifts from Archaic Hominins

Vernot, B., & Akey, J. M. (2014) · Current Biology

Pleistocene-Era Hominins and ArchaeologyForensic and Genetic Research

Cited by 13