Increased stem cell proliferation in atherosclerosis accelerates clonal hematopoiesis

Heyde, Alexander, Rohde, David, McAlpine, Cameron S., Zhang, Shuang, Hoyer, Friedrich F., Gerold, Jeffrey M., Cheek, David, Iwamoto, Yoshiko, Schloss, Maximilian J., Vandoorne, Katrien, Iborra-Egea, Oriol, Muñoz-Guijosa, Christian, Bayes-Genis, Antoni, Reiter, Johannes G., Craig, Morgan, Swirski, Filip K., Nahrendorf, Matthias, Nowak, Martin A., Naxerova, Kamila·2021·Cell

DOI 10.1016/j.cell.2021.01.049

Cited by (272)

Items 101–200 of 272

Impact of clonal haematopoiesis on atherosclerotic cardiovascular disease according to low-density lipoprotein cholesterol levels in general population
Heesun Lee, Han Song, Su‐Yeon Choi, Youngil Koh, Gangpyo Ryu, Hyo Eun Park, Ji Won Yoon, Min Joo Kim, Soie Chung, Jung Ho Bae et al. · 2024 · European Journal of Preventive Cardiology
Clonal hematopoiesis of indeterminate potential, health indicators, and risk of cardiovascular diseases among patients with diabetes: a prospective cohort study
Ying Sun, Yuefeng Yu, Lingli Cai, Bowei Yu, Wenying Xiao, Xiao Wei Tan, Yu Wang, Yingli Lu, Ningjian Wang · 2025 · Cardiovascular Diabetology
A vicious cycle in atherosclerosis
Aldons Jake Lusis · 2021 · Cell
Clonal Hematopoiesis of Indeterminate Potential: an Expanding Genetic Cause of Cardiovascular Disease
Romit Bhattacharya, Alexander G. Bick · 2021 · Current Atherosclerosis Reports
Clinical Significance of Clonal Hematopoiesis of Indeterminate Potential in Hematology and Cardiovascular Disease
Gregor Hoermann · 2022 · Diagnostics
Cardio-oncology: Shared Genetic, Metabolic, and Pharmacologic Mechanism
Yiqi Zhao, Hao Jia, Xiumeng Hua, Tao An, Jiangping Song · 2023 · Current Cardiology Reports
Expansion of mutation-driven haematopoietic clones is associated with insulin resistance and low HDL-cholesterol in individuals with obesity
Rosanne C. van Deuren, Johanna C. Andersson-Assarsson, Felipe M. Kristensson, Marloes Steehouwer, Kajsa Sjöholm, Per-Arne Svensson, Marc Pieterse, Christian Gilissen, Magdalena Taube, Peter Jacobson et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
Emerging Insights into Molecular Mechanisms of Inflammation in Myelodysplastic Syndromes
Veronica Vallelonga, Francesco Gandolfi, Francesca Ficara, Matteo Giovanni Della Porta, Serena Ghisletti · 2023 · Biomedicines
Understanding Normal and Pathological Hematopoietic Stem Cell Biology Using Mathematical Modelling
Mia Brunetti, Michael C. Mackey, Morgan Craig · 2021 · Current Stem Cell Reports
Microtubule affinity regulating kinase 4: A promising target in the pathogenesis of atherosclerosis
Yu‐Sheng Qin, Heng Li, Shuzhi Wang, Zongbao Wang, Chao‐Ke Tang · 2021 · Journal of Cellular Physiology
Clonal Hematopoiesis and Epigenetic Age Acceleration in Elderly Danish Twins
Mette Soerensen, Morten Tulstrup, Jakob Werner Hansen, Joachim Weischenfeldt, Kirsten Grønbæk, Kaare Christensen · 2022 · HemaSphere
Clonal Expansion in Cardiovascular Pathology
Lin, Alexander, Brittan, Mairi, Baker, Andrew H., Dimmeler, Stefanie, Fisher, Edward A., Sluimer, Judith C., Misra, Ashish · 2024 · JACC: Basic to Translational Science
Inflammation reprogramming and immunomodulation: Next-generation treatments for atherosclerosis
Robin P. Choudhury, Rupen Hargreaves, Jason Chai, Edward A A Fisher · 2025 · Cell Reports Medicine
How to measure and model cardiovascular aging
Luke Spray, Gavin David Richardson, Laura K. Booth, Judith Haendeler, Joachim Altschmied, Daniel I. Bromage, Sienna B Wallis, Konstantinos Stellos, Simon Tual‐Chalot, Ioakim Spyridopoulos · 2025 · Cardiovascular Research
Epitranscriptomics of Ischemic Heart Disease—The IHD-EPITRAN Study Design and Objectives
Vilbert Sikorski, Pasi P. Karjalainen, Daria Blokhina, Kati Oksaharju, Jahangir Khan, Shintaro Katayama, Helena Rajala, Satu Suihko, SUVI SIRKKU TUOHINEN, Kari Teittinen et al. · 2021 · International Journal of Molecular Sciences
Loss of Y chromosome at the interface between aging and Alzheimer’s disease
Xihan Guo · 2021 · Cellular and Molecular Life Sciences
Exposure to microbial products followed by loss of Tet2 promotes myelodysplastic syndrome via remodeling HSCs
Takako Yokomizo‐Nakano, Ai Hamashima, Sho Kubota, Jie Bai, Supannika Sorin, Yuqi Sun, Kenta Kikuchi, Mihoko Iimori, Mariko Morii, Akinori Kanai et al. · 2023 · The Journal of Experimental Medicine
Biomarkers in clonal haematopoiesis of indeterminate potential (CHIP) linking cardiovascular diseases, myeloid neoplasms and inflammation
Hui Shan Valerie Tan, Haowen Jiang, Samuel Sherng Young Wang · 2025 · Annals of Hematology
Contributions of Noncardiac Organ–Heart Immune Crosstalk and Somatic Mosaicism to Heart Failure: Current Knowledge and Perspectives
Marinos Kallikourdis, Jesse D. Cochran, Kenneth X. Walsh, Gianluigi Condorelli · 2025 · Circulation Research
From novel discovery tools and biomarkers to precision medicine—basic cardiovascular science highlights of 2021/22
Paul Charles Evans, Sean M. Davidson, Johann Wojta, Magnus Bäck, Sveva Bollini, Mairi Brittan, Alberico Luigi Catapano, Bill Chaudhry, Matthijs J M Cluitmans, Massimiliano Gnecchi et al. · 2022 · Cardiovascular Research
Scrutiny of genome‐wide somatic mutation profiles in centenarians identifies the key genomic regions for human longevity
Haotian Wang, Long Zhao, Liqin Yang, Ming‐Xia Ge, Xing‐Li Yang, Zong‐Liang Gao, Yupeng Cun, Fu‐Hui Xiao, Qing‐Peng Kong · 2023 · Aging Cell
Molecular and clinical aspects relevant for counseling individuals with clonal hematopoiesis of indeterminate potential
Anna Maria Cacic, Felicitas Isabel Schulz, Ulrich Germing, Sascha Dietrich, Norbert Gattermann · 2023 · Frontiers in Oncology
Association Between Clonal Hematopoiesis Driver Mutations, Immune Cell Function, and the Vasculometabolic Complications of Obesity
Helin Tercan, Benjamin C. Cossins, Rosanne C. van Deuren, Joost H.W. Rutten, Leo A. B. Joosten, Mihai Gheorghe Netea, Alexander Hoischen, Siroon Bekkering, Niels Peter Riksen · 2024 · Journal of the American Heart Association
Clonal hematopoiesis is associated with cardiovascular events in patients with stable coronary artery disease
Mihaela Ioana Dregoesc, Helin Tercan, Adrian Bogdan Țigu, Siroon Bekkering, Leo A. B. Joosten, Mihai Gheorghe Netea, Rosanne C. van Deuren, Alexander Hoischen, Niels Peter Riksen, Adrian Corneliu Iancu · 2024 · iScience
Clonal hematopoiesis landscape in frequent blood donors
Darja Karpova, Hector Huerga Encabo, Elisa Donato, Silvia Calderazzo, Michael Scherer, Miriam Llorian, Aino‐Maija Leppä, Roberto Würth, Patrick Stelmach, Despoina Papazoglou et al. · 2025 · Blood
Body mass index and adipose distribution have opposing genetic impacts on human blood traits
Christopher S. Thom, Madison B Wilken, Stella T Chou, Benjamin F. Voight · 2022 · eLife
A theory of evolutionary dynamics on any complex population structure reveals stem cell niche architecture as a spatial suppressor of selection
Yang Ping Kuo, César Nombela‐Arrieta, Oana Carja · 2024 · Nature Communications
The vicious and virtuous circles of clonal hematopoiesis
Nili Furer, Nathali Kaushansky, Liran I. Shlush · 2021 · Nature Medicine
Clonal Hematopoiesis: Confluence of Malignant and Nonmalignant Diseases
Amy Erica Lin, Philipp J. Rauch, Siddhartha Jaiswal, Benjamin L. Ebert · 2022 · Annual Review of Cancer Biology
Advances in understanding the molecular basis of clonal hematopoiesis
David A. Alagpulinsa, Mabel P. Toribio, Iad Alhallak, Robert J. Shmookler Reis · 2022 · Trends in Molecular Medicine
Micro‐environment alterations through time leading to myeloid malignancies
Kudzai Nyamondo, Helen Wheadon · 2022 · British Journal of Pharmacology
Somatic Mutations in “Benign” Disease
Osama Dasa, Thomas A Pearson · 2021 · New England Journal of Medicine
Lipoprotein metabolism mediates hematopoietic stem cell responses under acute anemic conditions
Kiyoka Saito, Mark van der Garde, Terumasa Umemoto, Natsumi Miharada, Julia Sjöberg, Valgarður Sigurðsson, Haruki Shirozu, Shunsuke Kamei, Višnja Radulović, Mitsuyoshi Suzuki et al. · 2024 · Nature Communications
Clonal hematopoiesis of indeterminate potential and type 2 diabetes mellitus among patients with STEMI: from a prospective cohort study combing bidirectional Mendelian randomization
Xiaoxiao Zhao, Jiannan Li, Shaodi Yan, Yu Guang Tan, Runzhen Chen, Nan Li, Jinying Zhou, Chen Liu, Peng Zhou, Yi Chen et al. · 2025 · Cardiovascular Diabetology
Regulation of Hematopoietic Stem Cell Dormancy and Quiescence: Insights into Regeneration and Disease
Jasmin Rettkowski, Nina Cabezas‐Wallscheid · 2025 · Annual Review of Cell and Developmental Biology
Putative homeostatic role of cancer driver mutations
Avanthika Venkatachalam, Eli Pikarsky, Yinon Ben‐Neriah · 2021 · Trends in Cell Biology
The CHIP-clinic as the catalyst of preventive medicine
Hans Carl Hasselbalch, Vibe Skov, Lasse Kjær, Trine Alma Knudsen, Christina Schjellerup Eickhardt‐Dalbøge, Christina Ellervik, Sabrina Cordua, Anders Lindholm Sørensen, Sarah Friis Christensen, Marie Hvelplund Kristiansen et al. · 2024 · Frontiers in Hematology
Implications of Clonal Hematopoiesis in Hematological and Non-Hematological Disorders
Qi Zhang, Rita Yim, Paul Lee, Lynn Chin, Vivian Li, Harinder Gill · 2024 · Cancers
Impact of Carrying DNMT3A or TET2 Mutations on Plaque Characteristics and Prognosis in Patients With STEMI Based on OCT
Qianhui Sun, Shengfang Wang, Ming Zeng, Minghao Liu, Chen Zhao, Boling Yi, Sining Hu, Bo Yu, Haibo Jia · 2025 · Circulation Cardiovascular Imaging
Clonal hematopoiesis of indeterminate potential and cardiovascular disease: Pathogenesis, clinical presentation, and future directions
Saivaroon Gajagowni, Steven Hopkins, Yusuf Kamran Qadeer, Salim S. Virani, Job A.J. Verdonschot, Catherine Callaghan Coombs, Christopher Ian Amos, Kevin Thomas Nead, Siddhartha Jaiswal, Chayakrit Krittanawong · 2024 · Progress in Cardiovascular Diseases
Clonal hematopoiesis of indeterminate potential: contribution to disease and promising interventions
Chongjie Li, Chunxiang Zhang, Xiuying Li · 2025 · Molecular and Cellular Biochemistry
TP53- mediated clonal hematopoiesis confers increased risk for incident peripheral artery disease
Seyedeh Maryam Zekavat, Vanesa Viana‐Huete, Saman Doroodgar Jorshery, María A. Zuriaga, Md Mesbah Uddin, Mark Trinder, Kaavya Paruchuri, Nuria Matesanz, Virginia Zorita, Alba Ferrer-Pérez et al. · 2021 · medRxiv
Clonal hematopoiesis, cardiovascular disease and cancer treatment-induced cardiotoxicity
Nan Zhang, Xu Tian, Dong-Kun Sun, Gary Tse, Bingxin Xie, Zhiqiang Zhao, Tong Liu · 2025 · Seminars in Cancer Biology
Clonal haematopoiesis - a novel entity that modifies pathological processes in elderly
Ekaterina Belotserkovskaya, Vasily Golotin, Burhan Uyanik, Oleg N. Demidov · 2023 · Cell Death Discovery
Association of clonal hematopoiesis of indeterminate potential with cardiometabolic multimorbidity progression and mortality: a prospective study of UK Biobank
Chenzhe Zuo, Dihan Fu, Yuanfeng Huang, Jinchen Li, Shujun Yang, Xunjie Cheng, Guogang Zhang, Tianqi Ma, Qunyong Peng, Yu Tan · 2025 · European journal of medical research
Emerging Role of Acquired Mutations and Clonal Hematopoiesis in Atherosclerosis ― Beyond Conventional Cardiovascular Risk Factors ―
María A. Zuriaga, José J. Fuster · 2021 · Circulation Journal
Social determinants of health and mortality on hyperuricemia adults in the USA from 2007 to 2016: a national cohort study
Zhengda Wang, Xiwen Chang, Hengshuo Chen, Yan Wang, Xiongfeng Tang, Yanguo Qin · 2025 · BMC Public Health
A malondialdehyde-activated fluorescent probe reveals lysosomal dysfunction in atherosclerosis
Xia Zhang, Guocheng Li, Yanhua Li, Na Li, Wei Pan, Bo Tang · 2025 · Chemical Science
Effect of clonal hematopoiesis on plaque morphology and prognosis in patients with acute myocardial infarction
Jiannan Li, Runzhen Chen, Jinying Zhou, Nan Li, Peng Zhou, Chen Liu, Li Song, Xiaoxiao Zhao, Yi Chen, Shaodi Yan et al. · 2025 · Genome Medicine
Mutation-dependent responses to sleep and exercise in clonal haematopoiesis
Teresa Gerhardt, Walter Jacob, Lena Gaebel, Merlin Heiser, Christopher Wolfram, Pacific Huynh, Tetsushi Nakao, Bernardo Gindri dos Santos, Pamela Toh, Aaron Douglas et al. · 2026 · Nature
Short-Term Western Diet Causes Rapid and Lasting Alterations of Bone Marrow Physiology
Remco T. A. Megens, Johan Duchêne, Mariaelvy Bianchini, Zoe Möller-Ramon, Christian Weber · 2023 · Thrombosis and Haemostasis
Hematopoietic Stem Cells as an Integrative Hub Linking Lifestyle to Cardiovascular Health
Xinliang Chen, Chaonan Liu, Junping Wang, Changhong Du · 2024 · Cells
Stem cell graft dose and composition could impact on the expansion of donor-derived clones after allogeneic hematopoietic stem cell transplantation – a virtual clinical trial
Thomas Stiehl · 2024 · Frontiers in Immunology
Exploring the Impact of Intermittent Fasting on Vascular Function and the Immune System: A Narrative Review and Novel Perspective
Elliot L. Graham, Tiffany L. Weir, Christopher L. Gentile · 2025 · Arteriosclerosis Thrombosis and Vascular Biology
Cooperative progression of colitis and leukemia modulated by clonal hematopoiesis via PTX3/IL-1β pro-inflammatory signaling
Hang He, Yuchen Wen, Hanzhi Yu, Jingjing Liu, Qingran Huo, Wenyan Jin, Zhiqin Wang, Guohui Du, Jun Du, Huaquan Wang et al. · 2024 · Genes & Diseases
Exploring the Associations Between Clonal Hematopoiesis of Indeterminate Potential, Myeloid Malignancy, and Atherosclerosis
Juan Bautista Menendez-Gonzalez, Neil P. Rodrigues · 2022 · Methods in molecular biology
JAK2 V617f in chronic myeloid leukemia: driving force or passive bystander?
Francesco Tarantini, Cosimo Cumbo, Antonella Zagaria, Elisa Parciante, Luisa Anelli, Nicoletta Coccaro, Giuseppina Tota, Crescenzio Francesco Minervini, Immacolata Redavid, Antonella Russo Rossi et al. · 2022 · Hematology
Modeling the evolutionary dynamics of clonal hematopoiesis
Sadegh Marzban, Thomas Stiehl, Zhuoer Xie, Morten Andersen, Jordan Andrew Snyder, Johanne Gudmand‐Hoeyer, Johnny T. Ottesen, Nathaniel V. Mon Père, Benjamin Werner, Weini Huang et al. · 2026 · Nature Genetics
Somatic genomics as a discovery engine for biomedicine
Simon F. Brunner, Inigo Martincorena, Gregory Mannino, Caroline S. Fox, Michael R. Stratton, Jacob R. Rubens, Peter J. Campbell, Hao Zhu · 2026 · Cell
Impact of Resistance on Therapeutic Design: A Moran Model of Cancer Growth
Mason S. Lacy, Adrianne L. Jenner · 2024 · Bulletin of Mathematical Biology
Dynamically adjusted cell fate decisions and resilience to mutant invasion during steady-state hematopoiesis revealed by an experimentally parameterized mathematical model
Natalia L. Komarova, Chiara Rignot, Angela G. Fleischman, Dominik Wodarz · 2024 · Proceedings of the National Academy of Sciences
Haematometabolism rewiring in atherosclerotic cardiovascular disease
Laurent Yvan‐Charvet, Thibault Barouillet, Coraline Borowczyk · 2025 · Nature Reviews Cardiology
Target practice: Opportunities for therapeutic intervention in CHIP and CCUS
Ayman Mohammad, John O Mascarenhas, Bridget Kelly Marcellino, Daniel I. Nathan · 2025 · Blood Reviews
Genome-wide mapping of arsenic-activated Nrf2 reveals metabolic and epigenetic reprogramming in induced pluripotent stem cells
Akimasa Seno, Zhuoyue Bi, Lisa Polin, Ziqi Liu, Yiran Qiu, Wenxuan Zhang, Aashna S. Pawar, Chitra Thakur, Masaharu Seno, Ziwei Wang et al. · 2025 · Redox Biology
Unveiling the Genetic Footprint: Exploring Somatic Mutations in Peripheral Arterial Disease Progression
Amankeldi A. Salybekov, Mehdi Hassanpour · 2023 · Biomedicines
Genetically influenced tobacco and alcohol use behaviors impact erythroid trait variation
Shriya Shivakumar, Madison B Wilken, Victor Tsao, Bárbara Domingues Bitarello, Christopher S. Thom · 2024 · PLoS ONE
Clonal hematopoiesis of indeterminate potential: clinical relevance of an incidental finding in liquid profiling
Gregor Hoermann · 2022 · Journal of Laboratory Medicine
Genome-wide associated variants of subclinical atherosclerosis among young people with HIV and gene-environment interactions
Jiayu He, Haijiang Lin, Yingying Ding, Xing Liu, Kelin Xu, Xiaoxiao Chen, Weiwei Shen, Sujuan Zhou, Miaochen Wang, Jingjing Xia et al. · 2022 · Journal of Translational Medicine
Proliferative advantage of specific aneuploid cells drives evolution of tumor karyotypes
Ivana Ban, Lucija Tomašić, Marianna Trakala, Iva M. Tolić, Nenad Pavin · 2023 · Biophysical Journal
Mischief in the marrow: a root of cardiovascular evil
Peter Libby, Matthias Nahrendorf, Filip K. Świrski · 2022 · European Heart Journal
Long-term longitudinal analysis of 4,187 participants reveals new insights into determinants of incident clonal hematopoiesis
Md Mesbah Uddin, Seyedmohammad Saadatagah, Abhishek Niroula, Bing Yu, Whitney Hornsby, Shriienidhie Ganesh, Kim Lannery, Art Schuermans, Michael C. Honigberg, Alexander G. Bick et al. · 2023 · medRxiv
Predicting which subsets of patients with myelodysplastic neoplasms are more likely to progress to overt chronic myelomonocytic leukemia
Violaine Tran Quang, Orianne Wagner‐Ballon, Ivan Sloma · 2024 · Leukemia & lymphoma/Leukemia and lymphoma
Tet2-mediated clonal hematopoiesis modestly improves neurological deficits and is associated with inflammation resolution in the subacute phase of experimental stroke
Evans, Megan A., Chavkin, Nicholas W., Sano, Soichi, Sun, Hanna, Sardana, Taneesha, Ravi, Ramya, Doviak, Heather, Wang, Ying, Yura, Yoshimitsu, Polizio, Ariel H. et al. · 2024 · Frontiers in Cellular Neuroscience
High-dose radiation preferentially induces the clonal expansion of hematopoietic progenitor cells over mature T and B cells in mouse bone marrow
Kengo Yoshida, Munechika Misumi, K. Hamasaki, Seishi Kyoizumi, Yasunari Satoh, Tatsuaki Tsuruyama, Arikuni Uchimura, Yoichiro Kusunoki · 2025 · Stem Cell Reports
Redefining Macrophage Heterogeneity in Atherosclerosis: A Focus on Possible Therapeutic Implications
Babunageswararao Kanuri, Krishna Prahlad Maremanda, Dipanjan Chattopadhyay, M. Faadiel Essop, Man K.S. Lee, Andrew James Murphy, Prabhakara R. Nagareddy · 2025 · Comprehensive physiology
Impaired CAMK4 Activity Limits Atherosclerosis and Reprograms Myelopoiesis
Azuah Lucrecia Gonzalez, Cristina M. Youwakim, Brenda F. Leake, Kristin Fuller, S.M. Jamshedur Rahman, Matthew M Dungan, Katherine Gu, Jesse L. Bonin, Ashley B. Cavnar, Danielle L. Michell et al. · 2025 · Arteriosclerosis Thrombosis and Vascular Biology
Profound connection between atherosclerosis and cancer: The role of galectin-3: A review
Xiaoyu Wang, Benkai Xin, Jingtong Yang, Xin Hu, Youzhong Wan · 2025 · International Journal of Biological Macromolecules
Clonal hematopoiesis of indeterminate potential: a multisystem hub bridging hematopoietic dysfunction with non-hematopoietic diseases
Jing-Lei Zhang, Shuo-Lan Tong, Qiqi Zhuang, Shengjie Jin, Jiaqiu Li, Jie Sun · 2025 · Military Medical Research
Common clonal hematopoiesis driver mutations have disparate effects on macrophage cytokines, clonal expansion, and atherogenesis.
Paul Carter, Lauren Kitt, Amanda Rodgers, Nichola L. Figg, Ang Zhou, Chengrui Zhu, Ziyang Wang, Peter Libby, Stephen Burgess, George S. Vassiliou et al. · 2025 · JCI Insight
Exploring the intricate cross-talk between clonal expansion and the bone marrow niche
Steven D. Ngo, Despoina Papazoglou, Hector Huerga Encabo, Dominique A. Bonnet · 2024 · Frontiers in Hematology
Revolutionising Cardio-Oncology Care with Precision Genomics
Jun Hua Chong, Charles T. H. Chuah, Caroline Guat Lay Lee · 2025 · International Journal of Molecular Sciences
Clonal hematopoiesis and atherosclerotic cardiovascular disease: A primer
María A. Zuriaga, José J. Fuster · 2021 · Clínica e Investigación en Arteriosclerosis
Regulators of clonal hematopoiesis and physiological consequences of this condition
Eunbee Park, Megan A. Evans, Kenneth X. Walsh · 2023 · The Journal of Cardiovascular Aging
Centenarians may hold a key to continued rise of human longevity
Johan Bredberg, Anders C. A. Bredberg · 2021 · Proceedings of the National Academy of Sciences
Clonal hematopoiesis and ischemic stroke
Nan Wang, Alan R. Tall · 2023 · Blood
Type 1 interferon perturbates clonal competition by reshaping human blood development
Lama, Chhiring, Isakov, Danielle, Rosenberg, Shira, Quijada-Álamo, Miguel, Saurty-Seerunghen, Mirca S., Moein, Sara, Nozais, Mathis, Abera, Tsega-Ab, Sakaguchi, Olivia, Totwani, Mansi et al. · 2026 · Nature Genetics
Targeting cholesterol metabolism in tumor and its immune microenvironment: opportunities and challenges
Ziyi Wang, Xinyan Li, Xiangyu Sun · 2025 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
Genetic factors contributing to atherosclerosis
Michael A. Raddatz, Hooman Allayee, Aldons Jake Lusis · 2026 · Current Opinion in Cardiology
Statin Use is Associated With Lower Odds of IBD-Related Surgery Among Patients With Moderate-to-Severe Inflammatory Bowel Disease
Jennifer D. Claytor, Palak Rajauria, Jellyana Peraza, Jean–Frédéric Colombel, Ryan C. Ungaro · 2025 · Inflammatory Bowel Diseases
Hematopoietic Stem Cell Fates and the Cellular Hierarchy of Mammalian Hematopoiesis: from Transplantation Models to New Insights from in Situ Analyses
Dania Shaban, Nay Najm, Lucie Droin, Anastasia Nijnik · 2024 · Stem Cell Reviews and Reports
JAK2V617F ‐dependent down regulation of SHP ‐1 expression participates in the selection of myeloproliferative neoplasm cells in the presence of TGF ‐β
Céline Aoun, Nabih Maslah, Saravanan Ganesan, Norman Salomao, Romane Gendron, Sarah Awan-Toor, Gil Letort, Panhong Gou, Mélina Bonnamy, Véronique Parietti et al. · 2024 · Journal of Cellular and Molecular Medicine
Deciphering Clonal Hematopoiesis of Indeterminate Potential
Zhi Yu, Caitlyn Vlasschaert, Pradeep Natarajan · 2025 · Journal of the American Society of Nephrology
Infection makes micro-CHIPs into macro-CHIPs
Jayakrishnan Gopakumar, Siddhartha Jaiswal · 2021 · Cell stem cell
Hematopoiesis of Indeterminate Potential and Atherothrombotic Risk
Andrew James Murphy, Dragana Dragoljevic, Pradeep Natarajan, Nan Wang · 2022 · Thrombosis and Haemostasis
Genetic and non-genetic mechanisms of inflammation may promote transformation in leukemia
Paresh Vyas · 2022 · Cell stem cell
Clonal hematopoiesis and atherosclerotic cardiovascular disease: A primer
María A. Zuriaga, José J. Fuster · 2023 · Clínica e Investigación en Arteriosclerosis (English Edition)
Atherosclerosis: cell biology and lipoproteins
Pernilla Katra, Harry Björkbacka · 2022 · Current Opinion in Lipidology
Frequent whole blood donations select for DNMT3A variants mediating enhanced response to erythropoietin
Darja Karpova, Hector Huerga Encabo, Elisa Donato, I. Kotova, Silvia Calderazzo, AM. Leppä, Jasper Panten, A. Przbylla, Erhard Seifried, Annette Kopp‐Schneider et al. · 2022 · medRxiv
The Genetic Determinants and Genomic Consequences of Non-Leukemogenic Somatic Point Mutations
J. Weinstock, Sharjeel A. Chaudhry, Maria Ioannou, Maria Viskadourou, P. Reventun, Y. Jakubek, L. Liggett, C. Laurie, J. Broome, Alyna T. Khan et al. · 2024 · medRxiv
Clinical progression of clonal hematopoiesis is determined by a combination of mutation timing, fitness, and clonal structure
Eric Latorre Crespo, Neil Robertson, Esra Gozde Kosebent, Louise MacGillivray, Lee Murphy, Md Mesbah Uddin, Eric A. Whitsel, Michael C. Honigberg, Alexander G. Bick, Alex P. Reiner et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)