Nahrendorf, Matthias

The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions

Nahrendorf, M., Swirski, F. K., Aikawa, E., Stangenberg, L., Wurdinger, T., Figueiredo, J.-L., Libby, P., Weissleder, R., & Pittet, M. J. (2007) · The Journal of Experimental Medicine

Cardiac Fibrosis and RemodelingAtherosclerosis and Cardiovascular Diseases

Cited by 2,300

Identification of splenic reservoir monocytes and their deployment to inflammatory sites

Swirski, F. K., Nahrendorf, M., Etzrodt, M., Wildgruber, M., Cortez-Retamozo, V., Panizzi, P., Figueiredo, J.-L., Kohler, R. H., Chudnovskiy, A., Waterman, P., et al. (2009) · Science

Immune cells in cancerAtherosclerosis and Cardiovascular Diseases

Cited by 2,221

Local proliferation dominates lesional macrophage accumulation in atherosclerosis

Robbins, C. S., Hilgendorf, I., Weber, G. F., Theurl, I., Iwamoto, Y., Figueiredo, J.-L., Gorbatov, R., Sukhova, G. K., Gerhardt, L. M. S., Smyth, D., et al. (2013) · Nature Medicine

Atherosclerosis and Cardiovascular DiseasesCholesterol and Lipid Metabolism

Cited by 1,041

Macrophages Facilitate Electrical Conduction in the Heart

Hulsmans, M., Clauss, S., Xiao, L., Aguirre, A. D., King, K. R., Hanley, A., Hucker, W. J., Wülfers, E. M., Seemann, G., Courties, G., et al. (2017) · Cell

Cardiac electrophysiology and arrhythmiasConnexins and lens biology

Cited by 1,011

Therapeutic siRNA silencing in inflammatory monocytes in mice

Leuschner, F., Dutta, P., Gorbatov, R., Novobrantseva, T. I., Donahoe, J. S., Courties, G., Lee, K. M., Kim, J. I., Markmann, J. F., Marinelli, B., et al. (2011) · Nature Biotechnology

RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery

Cited by 839

Imaging macrophages with nanoparticles

Weissleder, R., Nahrendorf, M., & Pittet, M. J. (2014) · Nature Materials

Nanoplatforms for cancer theranosticsNanoparticle-Based Drug Delivery

Cited by 809

Chronic variable stress activates hematopoietic stem cells

Heidt, T., Sager, H. B., Courties, G., Dutta, P., Iwamoto, Y., Zaltsman, A., von zur Muhlen, C., Bode, C., Fricchione, G. L., Denninger, J., et al. (2014) · Nature Medicine

Hematopoietic Stem Cell TransplantationStress Responses and Cortisol

Cited by 803

The human heart contains distinct macrophage subsets with divergent origins and functions

Bajpai, G., Schneider, C., Wong, N., Bredemeyer, A., Hulsmans, M., Nahrendorf, M., Epelman, S., Kreisel, D., Liu, Y., Itoh, A., et al. (2018) · Nature Medicine

Cardiac Fibrosis and RemodelingAtherosclerosis and Cardiovascular Diseases

Cited by 712

Modified mRNA directs the fate of heart progenitor cells and induces vascular regeneration after myocardial infarction

Zangi, L., Lui, K. O., von Gise, A., Ma, Q., Ebina, W., Ptaszek, L. M., Später, D., Xu, H., Tabebordbar, M., Gorbatov, R., et al. (2013) · Nature Biotechnology

Congenital heart defects researchMesenchymal stem cell research

Cited by 646

Relation between resting amygdalar activity and cardiovascular events: a longitudinal and cohort study

Tawakol, A., Ishai, A., Takx, R. A., Figueroa, A. L., Ali, A., Kaiser, Y., Truong, Q. A., Solomon, C. J., Calcagno, C., Mani, V., et al. (2017) · The Lancet

Cardiac Health and Mental HealthCardiac Imaging and Diagnostics

Cited by 636

Direct vascular channels connect skull bone marrow and the brain surface enabling myeloid cell migration

Herisson, F., Frodermann, V., Courties, G., Rohde, D., Sun, Y., Vandoorne, K., Wojtkiewicz, G. R., Masson, G. S., Vinegoni, C., Kim, J., et al. (2018) · Nature Neuroscience

Neuroinflammation and Neurodegeneration MechanismsBarrier Structure and Function Studies

Cited by 610

Differential Contribution of Monocytes to Heart Macrophages in Steady-State and After Myocardial Infarction

Heidt, T., Courties, G., Dutta, P., Sager, H. B., Sebas, M., Iwamoto, Y., Sun, Y., Da Silva, N., Panizzi, P., van der Laan, A. M., et al. (2014) · Circulation Research

Cardiac Fibrosis and RemodelingAtherosclerosis and Cardiovascular Diseases

Cited by 607

Noninvasive Vascular Cell Adhesion Molecule-1 Imaging Identifies Inflammatory Activation of Cells in Atherosclerosis

Nahrendorf, M., Jaffer, F. A., Kelly, K. A., Sosnovik, D. E., Aikawa, E., Libby, P., & Weissleder, R. (2006) · Circulation

Atherosclerosis and Cardiovascular DiseasesCerebrovascular and Carotid Artery Diseases

Cited by 602

Nanoparticle PET-CT Imaging of Macrophages in Inflammatory Atherosclerosis

Nahrendorf, M., Zhang, H., Hembrador, S., Panizzi, P., Sosnovik, D. E., Aikawa, E., Libby, P., Swirski, F. K., & Weissleder, R. (2008) · Circulation

Cardiac Imaging and DiagnosticsRadiopharmaceutical Chemistry and Applications

Cited by 559

Abandoning M1/M2 for a Network Model of Macrophage Function

Nahrendorf, M., & Swirski, F. K. (2016) · Circulation Research

Immune cells in cancerAtherosclerosis and Cardiovascular Diseases

Cited by 525

Sleep modulates haematopoiesis and protects against atherosclerosis

McAlpine, C. S., Kiss, M. G., Rattik, S., He, S., Vassalli, A., Valet, C., Anzai, A., Chan, C. T., Mindur, J. E., Kahles, F., et al. (2019) · Nature

Sleep and Wakefulness ResearchAtherosclerosis and Cardiovascular Diseases

Cited by 447

Single-nucleus profiling of human dilated and hypertrophic cardiomyopathy

Chaffin, M., Papangeli, I., Simonson, B., Akkad, A.-D., Hill, M. C., Arduini, A., Fleming, S. J., Melanson, M., Hayat, S., Kost-Alimova, M., et al. (2022) · Nature

Cardiac Fibrosis and RemodelingCardiomyopathy and Myosin Studies

Cited by 418

On-demand erythrocyte disposal and iron recycling requires transient macrophages in the liver

Theurl, I., Hilgendorf, I., Nairz, M., Tymoszuk, P., Haschka, D., Asshoff, M., He, S., Gerhardt, L. M. S., Holderried, T. A. W., Seifert, M., et al. (2016) · Nature Medicine

Phagocytosis and Immune RegulationIron Metabolism and Disorders

Cited by 412

Astrocytic interleukin-3 programs microglia and limits Alzheimer’s disease

McAlpine, C. S., Park, J., Griciuc, A., Kim, E., Choi, S. H., Iwamoto, Y., Kiss, M. G., Christie, K. A., Vinegoni, C., Poller, W. C., et al. (2021) · Nature

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 322

Exercise reduces inflammatory cell production and cardiovascular inflammation via instruction of hematopoietic progenitor cells

Frodermann, V., Rohde, D., Courties, G., Severe, N., Schloss, M. J., Amatullah, H., McAlpine, C. S., Cremer, S., Hoyer, F. F., Ji, F., et al. (2019) · Nature Medicine

Hematopoietic Stem Cell TransplantationExercise and Physiological Responses

Cited by 292

Increased stem cell proliferation in atherosclerosis accelerates clonal hematopoiesis

Heyde, A., Rohde, D., McAlpine, C. S., Zhang, S., Hoyer, F. F., Gerold, J. M., Cheek, D., Iwamoto, Y., Schloss, M. J., Vandoorne, K., et al. (2021) · Cell

Acute Myeloid Leukemia ResearchHematopoietic Stem Cell Transplantation

Cited by 267

Brain motor and fear circuits regulate leukocytes during acute stress

Poller, W. C., Downey, J., Mooslechner, A. A., Khan, N., Li, L., Chan, C. T., McAlpine, C. S., Xu, C., Kahles, F., He, S., et al. (2022) · Nature

Stress Responses and CortisolCancer, Stress, Anesthesia, and Immune Response

Cited by 234

IGF2BP2/IMP2-Deficient Mice Resist Obesity through Enhanced Translation of Ucp1 mRNA and Other mRNAs Encoding Mitochondrial Proteins

Dai, N., Zhao, L., Wrighting, D., Krämer, D., Majithia, A., Wang, Y., Cracan, V., Borges-Rivera, D., Mootha, V. K., Nahrendorf, M., et al. (2015) · Cell Metabolism

Adipose Tissue and MetabolismMetabolism, Diabetes, and Cancer

Cited by 188

Macrophages retain hematopoietic stem cells in the spleen via VCAM-1

Dutta, P., Hoyer, F. F., Grigoryeva, L. S., Sager, H. B., Leuschner, F., Courties, G., Borodovsky, A., Novobrantseva, T., Ruda, V. M., Fitzgerald, K., et al. (2015) · Journal of Experimental Medicine

Hematopoietic Stem Cell TransplantationAtherosclerosis and Cardiovascular Diseases

Cited by 180