The DOI matches its Crossref record; 64 of the 64 references it cites were found in a registry or an index.
Increased stem cell proliferation in atherosclerosis accelerates clonal hematopoiesis
Open accessAbstract
Clonal hematopoiesis, a condition in which individual hematopoietic stem cell clones generate a disproportionate fraction of blood leukocytes, correlates with higher risk for cardiovascular disease. The mechanisms behind this association are incompletely understood. Here, we show that hematopoietic stem cell division rates are increased in mice and humans with atherosclerosis. Mathematical analysis demonstrates that increased stem cell proliferation expedites somatic evolution and expansion of clones with driver mutations. The experimentally determined division rate elevation in atherosclerosis patients is sufficient to produce a 3.5-fold increased risk of clonal hematopoiesis by age 70. We confirm the accuracy of our theoretical framework in mouse models of atherosclerosis and sleep fragmentation by showing that expansion of competitively transplanted Tet2-/- cells is accelerated under conditions of chronically elevated hematopoietic activity. Hence, increased hematopoietic stem cell proliferation is an important factor contributing to the association between cardiovascular disease and clonal hematopoiesis.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“These cytokines display overlapping features, such as inducing cell cycle entry of HSCs and their differentiation, frequently toward the granulo-monocytic lineage 1,4-6,12-15 .”
From Type 1 interferon perturbates clonal competition by reshaping human blood development (2026) · cites this paper as [5]
Experimental — accuracy not yet measuredThe cited source says what the claim attributes to it.
In the citing paper
“The disease process itself has been suggested to reciprocally accelerate CH [41] (Figure 1).”
From Clonal hematopoiesis and inflammation – the perpetual cycle (2023) · cites this paper as [41]
The check wasn’t confident either way, so it gives no verdict — never disputed.
In the citing paper
“The isolated effects of individual inflammatory cytokines, including type 1 interferons (IFNa/b) 1-3 , type 2 IFN (IFNg) 4-6 , TNFa 7,8 , and IL-1 9-11 , have been well-documented in mouse hematopoietic development.”
From Type 1 interferon perturbates clonal competition by reshaping human blood development (2026) · cites this paper as [5]
Experimental — accuracy not yet measuredIn the citing paper
“While clonal expansion during normal ageing has not yet been observed in mice, it has been reported in mouse models for disease61 and in physiologically aged macaques62.”
From Ageing and rejuvenation of tissue stem cells and their niches (2023) · cites this paper as [61]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Age-related clonal hematopoiesis associated with adverse outcomes
Jaiswal, S., Fontanillas, P., Flannick, J., Manning, A., Grauman, P. V., Mar, B. G., Lindsley, R. C., Mermel, C. H., Burtt, N., Chavez, A., et al. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1408617 · Cited by 4,841
Clonal hematopoiesis and blood-cancer risk inferred from blood DNA sequence
Genovese, G., Kähler, A. K., Handsaker, R. E., Lindberg, J., Rose, S. A., Bakhoum, S. F., Chambert, K., Mick, E., Neale, B. M., Fromer, M., et al. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1409405 · Cited by 3,531
Fate Mapping Reveals Origins and Dynamics of Monocytes and Tissue Macrophages under Homeostasis
Yona, S., Kim, K.-W., Wolf, Y., Mildner, A., Varol, D., Breker, M., Strauss-Ayali, D., Viukov, S., Guilliams, M., Misharin, A., et al. (2013) · Immunity · doi:10.1016/j.immuni.2012.12.001 · Cited by 3,245
Kiel, M. J., Yilmaz, Ö. H., Iwashita, T., Yilmaz, O. H., Terhorst, C., & Morrison, S. J. (2005) · Cell · doi:10.1016/j.cell.2005.05.026 · Cited by 3,168
Clonal hematopoiesis and risk of atherosclerotic cardiovascular disease
Jaiswal, S., Natarajan, P., Silver, A. J., Gibson, C. J., Bick, A. G., Shvartz, E., McConkey, M., Gupta, N., Gabriel, S., Ardissino, D., et al. (2017) · New England Journal of Medicine · doi:10.1056/nejmoa1701719 · Cited by 2,683
Evolutionary Dynamics: Exploring the Equations of Life
NOWAK, M. A. (2006) · doi:10.2307/j.ctvjghw98 · Cited by 2,438
Self-citationClonal hematopoiesis of indeterminate potential and its distinction from myelodysplastic syndromes
Steensma, D. P., Bejar, R., Jaiswal, S., Lindsley, R. C., Sekeres, M. A., Hasserjian, R. P., & Ebert, B. L. (2015) · Blood · doi:10.1182/blood-2015-03-631747 · Cited by 1,971
Age-related mutations associated with clonal hematopoietic expansion and malignancies
Xie, M., Lu, C., Wang, J., McLellan, M. D., Johnson, K. J., Wendl, M. C., McMichael, J. F., Schmidt, H. K., Yellapantula, V., Miller, C. A., et al. (2014) · Nature Medicine · doi:10.1038/nm.3733 · Cited by 1,874
Clonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis development in mice
Fuster, J. J., MacLauchlan, S., Zuriaga, M. A., Polackal, M. N., Ostriker, A. C., Chakraborty, R., Wu, C.-L., Sano, S., Muralidharan, S., Rius, C., et al. (2017) · Science · doi:10.1126/science.aag1381 · Cited by 1,536
Tacke, F., Alvarez, D., Kaplan, T. J., Jakubzick, C., Spanbroek, R., Llodra, J., Garin, A., Liu, J., Mack, M., van Rooijen, N., et al. (2007) · Journal of Clinical Investigation · doi:10.1172/jci28549 · Cited by 1,323
Flagged first, then by citations
Cited by
Sorted by citations
Items 201–272 of 272
Prutsch, N., Vromman, A., Leeper, B. A., Chen, M., Keating, J. H., He, S., Berezovskaya, A., Ren, S., Gomes, M. J., Folco, E. J. E., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.06.12.658927 · Cited by 3
Sleep calibrates atherosclerotic cardiovascular disease
Cohen, O. S., Shah, N. A., & McAlpine, C. S. (2022) · Nature Cardiovascular Research · doi:10.1038/s44161-022-00190-x · Cited by 2
Self-citationWang, H., Yan, H., Chen, W., Tang, H., Pei, Y.-Z., Shan, Q., Cang, J., Miao, C., Tan, L., & Tan, L. (2023) · British Journal of Anaesthesia · doi:10.1016/j.bja.2023.10.035 · Cited by 2
Kristiansen, M. H., Skov, V., Larsen, M. K., Kjær, L., Nielsen, C. H., Hasselbalch, H. C., & Wienecke, T. (2025) · British Journal of Haematology · doi:10.1111/bjh.20242 · Cited by 2
Genetic determinants and genomic consequences of non-leukemogenic somatic point mutations
Weinstock, J. S., Chaudhry, S. A., Ioannou, M., Viskadourou, M., Reventún, P., Jakubek, Y. A., Liggett, L. A., Laurie, C. A., Broome, J., Khan, A., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-64236-x · Cited by 8
Xue, L., Bhattacharya, R., Uddin, M. M., Nakao, T., Zou, R. S., Patel, A. P., Haidermota, S., Niroula, A., Viscosi, V., Postupaka, D., et al. (2025) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.125.322896 · Cited by 3
Shen, X., Song, Y., Zhao, H., Xu, J., Li, J., Du, M., Wang, H., Chen, S., Liu, F., Yuan, D., et al. (2026) · BMC Medicine · doi:10.1186/s12916-026-04711-4 · Cited by 2
Yang, X., Wang, L., Liu, Y., Guan, H., Wu, Y., Wang, B., Zhu, L., Zhang, S., & Li, Q. (2026) · International Journal of Cardiology · doi:10.1016/j.ijcard.2026.134276 · Cited by 2
Self-citationShi, C., Zhang, K., Zhao, Z., Wang, Y., Xu, H., & Wei, W. (2023) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2023.1080563 · Cited by 2
Mathematical modelling of clonal reduction therapeutic strategies in acute myeloid leukemia
Brunetti, M., Iasenza, I. A., Jenner, A. L., Raynal, N. J. ‐., Eppert, K., & Craig, M. (2024) · Leukemia Research · doi:10.1016/j.leukres.2024.107485 · Cited by 2
Self-citationImpacts of cationic lipid–DNA complexes on immune cells and hematopoietic cells in vivo
Cong, X., Tan, H., Lv, Y., Mao, K., Xin, Y., Wang, J., Meng, X., Guan, M., Wang, H., Yang, Y., et al. (2024) · Biomaterials Science · doi:10.1039/d4bm00148f · Cited by 2
Update on Clonal Hematopoiesis
Bolton, K. L. (2021) · Clinical Lymphoma Myeloma & Leukemia · doi:10.1016/s2152-2650(21)01199-x · Cited by 2
Yu, X., Qian, N., & Wang, Y. (2023) · Molecular Biology Reports · doi:10.1007/s11033-022-08118-1 · Cited by 2
Detecting and quantifying clonal selection in somatic stem cellsPreprint
Körber, V., Ansari‐Pour, N., Jakobsen, N. A., Moore, R., Claudino, N., Metzner, M., Hörsch, F., Usukhbayar, B., Salazar, M. A., Newman, S., et al. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.12.15.472780 · Cited by 2
McClatchy, J., Strogantsev, R., Wolfe, E., Lin, H., Mohammadhosseini, M., Davis, B. A., Eden, C. O., Goldman, D., Fleming, W., Conley, P., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.09.15.507688 · Cited by 2
A Vicious Circle of Clonal Haematopoiesis of Indeterminate Potential and Cardiovascular Disease
Ehlert, C. A., & Hilgendorf, I. (2021) · Hämostaseologie · doi:10.1055/a-1576-4059 · Cited by 1
Cannas, G., Elhamri, M., & Thomas, X. (2024) · Oncology and Therapy · doi:10.1007/s40487-024-00274-7 · Cited by 1
Baptista, E. C. M. S., Pereira, C. S. G. P., García, P. A., Ferreira, I. C. F. R., & Barreira, J. C. M. (2025) · Clinical Nutrition ESPEN · doi:10.1016/j.clnesp.2025.01.026 · Cited by 1
Wagner, S., Thielecke, L., & Glauche, I. (2025) · Computers in Biology and Medicine · doi:10.1016/j.compbiomed.2025.111079 · Cited by 1
Healthy lifestyle attenuates the clonal hematopoiesis-associated coronary artery disease risk
Yang, Y., Shen, X., Huang, K., Liu, H., Li, J., Liu, F., Chen, S., Cao, J., Li, H., Liu, X., et al. (2025) · Fundamental Research · doi:10.1016/j.fmre.2025.09.012 · Cited by 1
Morley, A. P., Ardissino, M., Carter, P., Raman, B., Mead, A. J., Quirós, P. M., Vassiliou, G. S., & Raisi‐Estabragh, Z. (2025) · Open Heart · doi:10.1136/openhrt-2025-003602 · Cited by 3
Plasticity and stringency: rethinking stem cell division modes
Bener, M. B., & Inaba, M. (2026) · Biochemical Society Transactions · doi:10.1042/bst20250202 · Cited by 1
Ph-chromosome-negative myeloproliferative neoplasms: clonal dynamics are the name of the game
Noorafrooz, M., Noorafrooz, R., Barosi, G., & Gale, R. P. (2026) · Blood Reviews · doi:10.1016/j.blre.2026.101385 · Cited by 1
Bone marrow rewired: Trained immunity and clonal hematopoiesis in metabolic disease
Chronopoulos, J., Hajishengallis, G., & Chavakis, T. (2026) · Metabolism · doi:10.1016/j.metabol.2026.156603 · Cited by 2
Oral Health, Periodontitis, and Respiratory Diseases: Biological Pathways
Vacaru, R.-P., Didilescu, A. C., & Scannapieco, F. A. (2026) · Journal of Periodontal Research · doi:10.1111/jre.70126 · Cited by 1
Clonal Hematopoiesis in Colorectal Cancer: Mechanisms and Implications
Xia, C., Lu, Y., & Gu, J. (2026) · Cancer Medicine · doi:10.1002/cam4.72151 · Cited by 1
Modeling the temporal dynamics of clonal hematopoiesis
Jaiswal, S., & Bick, A. G. (2022) · Nature Cardiovascular Research · doi:10.1038/s44161-022-00086-w · Cited by 1
Common in atherogenesis and carcinogenesis: clonal hematopoiesis
Слепцов, А. А., Nazarenko, M. S., & Puzyrev, V. P. (2023) · Russian Journal of Cardiology · doi:10.15829/1560-4071-2023-5511 · Cited by 4
Itaya, N., Fukami, A., Kakuma, T., & Fukumoto, Y. (2021) · Nutrients · doi:10.3390/nu13082663 · Cited by 1
Einfluss der klonalen Hämatopoese auf nicht-hämatologische Erkrankungen und Alterungsprozesse
Rieger, M. A. (2022) · Die Innere Medizin · doi:10.1007/s00108-022-01409-6 · Cited by 1
Talesh, G. A., Vitale, D., Langfelder, P., Azardaryany, M. K., Berry, M. J., Belgard, T. G., Choo, J. M., Rogers, G. B., Ho, V., Ramezani–Moghadam, M., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.04.16.488543 · Cited by 1
Lee, H., Song, H., Koh, Y., Park, H. E., Yoon, J. W., Kim, M. J., Chung, S., Bae, J. H., Choi, S. H., Choi, S., et al. (2022) · medRxiv · doi:10.1101/2022.06.09.22276170 · Cited by 1
Lyon, P. D., Leesang, T. E., Brabson, J. P., Do, K., Dalzell, M., Nivelo, L. A., Lam, M. Q., Peci, A., Fang, B., Strippoli, V., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.08.22.671600 · Cited by 1
Fuelling the fire : Immunometabolism of monocytes and macrophages in obesity & diabetes
van Dierendonck, X. A. M. H. (2021) · doi:10.18174/545884
New insights into the dynamics of age-related clonal hematopoiesis
Zuriaga, M. A., & Fuster, J. J. (2022) · The Journal of Cardiovascular Aging · doi:10.20517/jca.2022.38
Clonal hematopoiesis in idiopathic cytopenia of undetermined significancePreprint
Wu, H., Gu, C., Liu, S., Dong, Q., Lin, D., Wang, L., Wang, X., Cui, S., Zhao, L., Liu, X., et al. (2023) · Research Square · doi:10.21203/rs.3.rs-2430010/v1
Neuendorff, N. R., Bittner, A., Flossdorf, S., Mauer, T., Schmitz, F., Neuhoff, N. V., Köster, J., Mölder, F., Schneider, M., Turki, A. T., et al. (2023) · Ageing and Cancer Research & Treatment · doi:10.37155/2972-4759-2023-01-01-4 · Cited by 1
Herz und Blut: klonale Hämatopoese
Dimmeler, S., & Zeiher, A. M. (2024) · Herz · doi:10.1007/s00059-024-05237-2
He, J., Lin, H., Ding, Y., Liu, X., Xu, K., Chen, X., Shen, W., Zhou, S., Wang, M., Xia, J., et al. (2023) · Figshare · doi:10.6084/m9.figshare.22599149
He, J., Lin, H., Ding, Y., Liu, X., Xu, K., Chen, X., Shen, W., Zhou, S., Wang, M., Xia, J., et al. (2023) · Figshare · doi:10.6084/m9.figshare.22599134
He, J., Lin, H., Ding, Y., Liu, X., Xu, K., Chen, X., Shen, W., Zhou, S., Wang, M., Xia, J., et al. (2023) · Figshare · doi:10.6084/m9.figshare.22599137
He, J., Lin, H., Ding, Y., Liu, X., Xu, K., Chen, X., Shen, W., Zhou, S., Wang, M., Xia, J., et al. (2023) · Figshare · doi:10.6084/m9.figshare.22599146
He, J., Lin, H., Ding, Y., Liu, X., Xu, K., Chen, X., Shen, W., Zhou, S., Wang, M., Xia, J., et al. (2023) · Figshare · doi:10.6084/m9.figshare.22599140
He, J., Lin, H., Ding, Y., Liu, X., Xu, K., Chen, X., Shen, W., Zhou, S., Wang, M., Xia, J., et al. (2023) · Figshare · doi:10.6084/m9.figshare.22599131
Clonal hematopoiesis: a shared risk factor for cardiovascular diseases and tumors
Zha, L., & Cheng, X. C. (2024) · Oncology and Translational Medicine · doi:10.1097/ot9.0000000000000029
ВЛИЯНИЕ КЛОНАЛЬНОГО ГЕМАТОПОЭЗА С НЕОПРЕДЕЛЕННЫМ ПОТЕНЦИАЛОМ (CHIP) НА РАЗВИТИЕ АТЕРОСКЛЕРОЗА
Bekbossynova, M. S., Andosova, S. A., Rysbekova, A., & Daniyarova Gulnur, D. (2024) · Ġylym men densaulyķ saķtau. · doi:10.34689/sh.2024.26.4.023
Zherniakova, A., Крысюк, О. Б., & Kunevich, Y. O. (2024) · Extreme Medicine · doi:10.47183/mes.2024-26-4-5-12 · Cited by 1
Trade-offs and Progress in Cancer Science
Plutynski, A. (2025) · Synthese Library/Synthese library · doi:10.1007/978-3-031-88213-5_13
Causal relationship between immune cells and myocardial infarction: A Mendelian randomization study
Xu, Y., Yang, J., Xue, R., Zhang, G., & Zhang, Y. (2025) · Medicine · doi:10.1097/md.0000000000043682
Evans, P. C., Davidson, S. M., Wojta, J., Bäck, M., Bollini, S., Brittan, M., Catapano, A. L., Chaudhry, B., Cluitmans, M., Gnecchi, M., et al. (2022) · Zurich Open Repository and Archive (University of Zurich) · doi:10.5167/uzh-219832
He, J., Lin, H., Ding, Y., Liu, X., Xu, K., Chen, X., Shen, W., Zhou, S., Wang, M., Xia, J., et al. (2023) · Figshare · doi:10.6084/m9.figshare.22599128
Laivuori, M., Lokki, A. I., Pellinen, T. S., Mäyränpää, M. I., Venermo, M. A., McGinigle, K. L., Lokki, M., & Sinisalo, J. P. (2026) · JVS Vascular Science · doi:10.1016/j.jvssci.2026.100416
Rôle des cellules de Kupffer dans l'homéostasie du cholestérol
Fima, R. (2022) · theses.fr (ABES) · doi:10.70675/57f4dd66z9dc1z45c7z8619z4ddb93538c40
Investigating the tumor-induced modifications of hematopoiesis during breast cancer
Gerber-Ferder, Y. (2022) · theses.fr (ABES) · doi:10.70675/90368efbz219dz41adz90b3z2fcc7e359988
Elucidating the role of SHP-1 in TGF-ß resistance in myeloproliferative neoplasms
Aoun, C. (2024) · theses.fr (ABES) · doi:10.70675/3146017czdefbz4c4az96f3z2d837d53ea19
Stem cells and pyroptosis in atherosclerosis
Rasmi, Y., Mahheidari, N., Madan, A., Dehghani, L., & Ghoshal, K. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-40471-9.00011-2
Hematopoietic somatic mutations in atherosclerotic cardiovascular disease
Ramos-Neble, B. L., & Fuster, J. J. (2026) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2026.120718
TET2 ‐ CHIP : From Mutation to Malady
Jian, H., Sun, M., Xia, X., Su, C., Su, K., Xu, J. L., Yuan, Y., Li, C., Yu, M., & Cheng, X. (2026) · The FASEB Journal · doi:10.1096/fj.202600383r
Mathematical modeling of JAK2V617F clonal expansion in a general population cohort
Snyder, J. A., Andersen, M., Gudmand‐Hoeyer, J., Larsen, M. K., Skov, V., Kjær, L., Eickhardt‐Dalbøge, C. S., Knudsen, T. A., Ellervik, C., Hasselbalch, H. C., et al. (2026) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2507773123 · Cited by 1
Is clonal haematopoiesis the missing link between lupus and cardiovascular disease?
Shamsi, A., Wincup, C., Pericleous, C., Tariq, F., Sadler, M., Quek, L. S., & Bromage, D. I. (2026) · Rheumatology · doi:10.1093/rheumatology/keag330 · Cited by 1
Inflammation in atherosclerosis: Drivers, mechanisms and therapies
Su, Z., & Xu, S. (2026) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2026.06.047 · Cited by 1
Krasińska, B., Staniewski, A., Kalus, O., Maćkowiak, J., Szymańska, Z., Gramala, Z., Zalewska, K., Karpiński, M., Mertowska, P., Rolek, Ł., et al. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27135900
Research progress on targeted regulatory proteins in the prevention and treatment of atherosclerosis
Wei, Y., Zhang, F., Liao, Y., Zhao, Y., & Guo, J. Z. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1791961
Sleep disorders and cardiovascular diseases
Pan, X., Hussain, Y., & Dar, M. I. (2026) · Trends Open · doi:10.1016/j.treopn.2026.05.013
Li, J., Zhao, Y., & Bai, M. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1903190
Tang, B., Kuai, Y., Ye, Z., Zhao, X., Fan, C., Huang, M., Luo, Y., & Li, C. (2026) · Cell investigation. · doi:10.1016/j.clnves.2026.100088 · Cited by 1
Powell, N., Cubbon, R. M., Bailey, M. A., Griffin, K. J., Roberts, L. D., & Cheng, C. W. (2026) · Vascular Medicine · doi:10.1177/1358863x261437058
Deckers, J., van Elsas, Y., Versteeg, I., Anbergen, T., Toner, Y. C., Grao-Roldán, C., Cole, J. E., Umali, M., Wang, W., Nauta, S. A., et al. (2026) · JACC Basic to Translational Science · doi:10.1016/j.jacbts.2026.101660
Self-citationJAK2V617F Mutation in Ischemic Stroke: Bridging Hematology and Stroke Neurology
Kristiansen, M. H., Kjær, L., Skov, V., Larsen, M. K., Ellervik, C., Nielsen, C. H., Hasselbalch, H. C., & Wienecke, T. (2026) · Journal of the American Heart Association · doi:10.1161/jaha.126.050497
Ünsal, Ş. E. (2026) · Frontiers in Oncology · doi:10.3389/fonc.2026.1943135
Harkot, O., Jäger, R., Kampf, S., Gurbisz, M., Nackenhorst, M. C., Wojta, J., Hengstenberg, C., Haring, B., Esterbauer, H., Neumayer, C., et al. (2026) · Atherosclerosis Plus · doi:10.1016/j.athplu.2026.100617
Somatic Blood Mosaicism and Psychiatric Disease: Current Evidence and Causal Limits
Belbe, A.-A., Pîrlog, L.-M., Pilatec, A.-N., Militaru, M.-S., Iordănescu, I. I., & Cătană, A. (2026) · Genes · doi:10.3390/genes17101224
Metadata
- Authors
- Heyde, A., Rohde, D., McAlpine, C. S., Zhang, S., Hoyer, F. F., Gerold, J. M., Cheek, D., Iwamoto, Y., Schloss, M. J., Vandoorne, K., Iborra-Egea, O., Muñoz-Guijosa, C., Bayes-Genis, A., Reiter, J. G., Craig, M., Swirski, F. K., Nahrendorf, M., Nowak, M. A., & Naxerova, K.
- Affiliations
- Harvard University (US)
- Hospital Universitari Germans Trias i Pujol (ES)
- Stanford University (US)
- Centre Hospitalier Universitaire Sainte-Justine (CA)
- Corresponding author
- Naxerova, Kamila
- ORCID
- Heyde, Alexander
- Rohde, David
- McAlpine, Cameron S.
- Zhang, Shuang
- Hoyer, Friedrich F.
- Gerold, Jeffrey M.
- Cheek, David
- Iwamoto, Yoshiko
- Schloss, Maximilian J.
- Vandoorne, Katrien
- Iborra-Egea, Oriol
- Muñoz-Guijosa, Christian
- Reiter, Johannes G.
- Craig, Morgan
- Swirski, Filip K.
- Nahrendorf, Matthias
- Nowak, Martin A.
- Naxerova, Kamila
- Venue
- Cell
- Publisher
- Elsevier BV
- Published
- 2021-03
- Volume
- 184
- Issue
- 5
- Pages
- 1348-1361.e22
- ISSN
- 0092-8674 (ISSN-L)
- PMC
- PMC8109274
- OpenAlex
- W3130296909
- Cited by
- 267
- References
- 64
- Citations by year
- 2026: 33 · 2025: 48 · 2024: 45 · 2023: 47 · 2022: 61 · 2021: 33
- FWCI
- 31.37
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- www.elsevier.com/legal/tdmrep-license (tdm)
- www.elsevier.com/open-access/userlicense/1.0/ (vor, 368 d)
- doi.org/10.15223/policy-017 (stm-asf)
- doi.org/10.15223/policy-037 (stm-asf)
- doi.org/10.15223/policy-012 (stm-asf)
- doi.org/10.15223/policy-029 (stm-asf)
- doi.org/10.15223/policy-004 (stm-asf)
- Locations
- Cell (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health
- National Science Foundation
- National Heart, Lung, and Blood Institute
- Topics
- Health Sciences › Medicine › Hematology › Acute Myeloid Leukemia Research
- Health Sciences › Medicine › Hematology › Hematopoietic Stem Cell Transplantation
- Life Sciences › Immunology and Microbiology › Immunology › Atherosclerosis and Cardiovascular Diseases
- Keywords
- clonal hematopoiesis, atherosclerosis, hematopoietic stem cell proliferation, somatic evolution, driver mutations, cardiovascular risk, TET2, sleep fragmentation, hematopoietic stem cell transplantation
- MeSH terms
- Clonal Hematopoiesis, Aging, Animals, Apolipoproteins E, Bone Marrow, Disease Models, Animal, Female, Hematopoietic Stem Cells, Humans, Mice, Inbred C57BL, Models, Biological, Sleep Deprivation, Cell Proliferation, Atherosclerosis, Mice, Clonal Evolution
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
