Early Alzheimer’s disease pathology in human cortex involves transient cell states

Cited by (213)

Items 101–200 of 213

1. Comparative mapping of single‐cell transcriptomic landscapes in neurodegenerative diseases
   Elliot Keats Shwab, Zhaohui Man, Daniel C. Gingerich, Julia Gamache, Melanie E. Garrett, Geidy E. Serrano, Thomas G. Beach, Gregory E. Crawford, Allison E. Ashley‐Koch, Ornit Chiba‐Falek · 2025 · Alzheimer s & Dementia
2. Comparative gene regulatory network analysis in Alzheimer’s disease and major depressive disorder identifies shared core regulatory circuits
   Hanne Puype, Joke Deschildre, Vanessa Vermeirssen · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
3. SRRM2 haploinsufficiency drives SynGAP-γ reduction, AGAP3 mis-splicing, and oligodendrocyte deficits in a mouse model of schizophrenia
   Sameer Aryal, Chuhan Geng, Margaret A. Yin, Min Jee Kwon, Zohreh Farsi, Nathaniel Goble, Ahmet S. Asan, Kira S. Brenner, Nate Shepard, Ana Geller et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
4. Effect of knockdown LncRNA SNHG1 on autophagic function in SH-SY5Y cells: a model of Alzheimer’s disease (AD)
   Xiaoxu Li, Xu-Sheng Yan, Chun-Jie Zhang, Yichi Zhang, Xiao-Jing Su, He Zhang, Jin Yang, Yilong Zhang, Zhiying Zhao · 2025 · Journal of Toxicology and Environmental Health
5. Human brain cell types shape host-rabies virus transcriptional interactions revealing a preexisting pro-viral astrocyte subpopulation
   Lena Feige, Karl Young, Juan‐Pablo Cerapio, Tatsuya Kozaki, Lauriane Kergoat, Valentina Libri, Florent Ginhoux, Milena Hasan, Lamya Ben Ameur, Gregory Chin et al. · 2025 · Cell Reports
6. Quercetin Targets HSP90α and Regulates Keap1/Nrf2 Pathway to Inhibit Crosstalk between Apoptosis and Ferroptosis in Oxidatively Stressed Neurons
   Jing Liu, Z. Zhang, Guran Yu, Xu Han · 2025 · Journal of Biochemical and Molecular Toxicology
7. Lactate metabolism links reactive microglia, amyloid pathology, and Aβ dynamics
   Clair C. Ashley, Nicholas J. Constantino, Ryan J. Pettit‐Mee, James Andy Snipes, Kai Saito, Riley E. Irmen, Rui Zhang, Evan M. Neary, Matthew J. Lanning, Celeste M M. Karch et al. · 2026 · Journal of Neuroinflammation
8. PS1/gamma-secretase acts as rogue chaperone of glutamate transporter EAAT2/GLT-1 in Alzheimer’s disease
   Florian Perrin, Lauren C. Anderson, Shane P. C. Mitchell, Priyanka Sinha, Yuliia Turchyna, Masato Maesako, Mei CQ Houser, Can Martin Zhang, Steven L. Wagner, Rudolph E. Tanzi et al. · 2024 · Acta Neuropathologica Communications
9. Integrative single-cell and cell-free plasma RNA transcriptomics identifies biomarkers for early non-invasive AD screening
   Li Wu, Renxin Zhang, Yichao Wang, Shao‐Xing Dai, Naixue Yang · 2025 · Frontiers in Aging Neuroscience
10. Spatial2GWAS: a database for linking spatial transcriptomic regions with GWAS traits
    Xi Hu, Aoqi Wang, Huan Yu, Pora Kim, Xiaobo Zhou · 2025 · Nucleic Acids Research
11. A single-cell eQTL atlas of the human cerebellum reveals vulnerability of oligodendrocytes in essential tremor
    Charles-Etienne Castonguay, Farah Aboasali, Miranda Medeiros, Théodore Becret, Zoe Schmilovich, Anouar Khayachi, Alex H. Rajput, Patrick A. Dion, Guy Armand Rouleau · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
12. Lysosomes cell autonomously regulate myeloid cell states and immune responses
    Tejwani, Leon, Balak, Christopher, Skuja, Lukas L., Tatarakis, David, Rana, Anil, Fitzgerald, Gabriel A., Ha, Connie, Lunkes de Melo, Gabrielly, Sun, Elizabeth W., Heffner, Catherine M. et al. · 2024
13. Tau mediates the reshaping of the transcriptional landscape toward intermediate Alzheimer’s disease stages
    Giacomo Siano, Martina Varisco, Marco Terrigno, Congwei Wang, Arianna Scarlatti, Vincenzo Iannone, Marco Groth, Marie‐Christine Galas, Jeroen J.M. Hoozemans, Alessandro Cellerino et al. · 2025 · Frontiers in Cell and Developmental Biology
14. A Question of Origins: Non-neuronal Sources of Amyloid-β
    Andrew Octavian Sasmita, Constanze Depp · 2026 · Neuroscience Bulletin
15. Glioinflammation: disease-associated microglia and astrocytes in psychiatric disorders, neurodegeneration, and senescence
    Kumiko Uemura, Shunya Hiro, Suthinee Attachaipanich, Ruixue Du, Nur Intan Saidaah Mohamed Yusof, Miyu Kinoshita, Momoka Hikosaka, Gen Ohtsuki · 2026 · Frontiers in Cellular Neuroscience
16. Potential Protection Against Parkinson’s Disease by Ergothioneine—Nature’s Multifactorial Neuroprotectant
    Teddy J. W. Tng, Irwin Kee-Mun Cheah, Barry B. Halliwell, Kah‐Leong Lim · 2026 · Antioxidants
17. Secreted GPNMB enhances uptake of fibrillar alpha-synuclein in a non-cell-autonomous process that can be blocked by anti-GPNMB antibodies
    Marc Carceles‐Cordon, Eliza M. Brody, Masen L. Boucher, Michael D. Gallagher, R. Tyler Skrinak, Travis L. Unger, Cooper K Penner, Adama J. Berndt, Sromona Das, Katie Lam et al. · 2026 · Neuron
18. Lysosomal dysfunction drives a transcriptional and epigenetic signature found in disease-associated microglia in neurodegenerative diseases
    Christopher D. Balak, Johannes C. M. Schlachetzki, Addison J. Lana, Elizabeth West, Christine Hong, Jordan DuGal, Yi Zhou, Benjamin Li, Nathanael J. Spann, Payam A. Saisan et al. · 2026 · Immunity
19. Deep learning assisted quantitative analysis of Aβ and microglia in patients with idiopathic normal pressure hydrocephalus in relation to cognitive outcome
    Antti Johannes Luikku, Ossi Nerg, Anne Maria Koivisto, Tuomo Hänninen, Antti Junkkari, Susanna Kemppainen, Sini-Pauliina Juopperi, Rosa Sinisalo, Alli Pesola, Hilkka Soininen et al. · 2024 · Journal of Neuropathology & Experimental Neurology
20. Early metabolic changes in the brain of Alzheimer’s disease rats are driven by GLAST+ cells
    William J Morrey, Kelly Ceyzériat, Quentin Amossé, Aurélien M. Badina, Ben Dickie, Ingo Schießl, Stergios Tsartsalis, P. Millet, Hervé Boutin, Benjamin B. Tournier · 2025 · Journal of Cerebral Blood Flow & Metabolism
21. Mechanisms driving epigenetic and transcriptional responses of microglia in a neurodegenerative lysosomal storage disorder model
    Christopher D. Balak, Johannes C. M. Schlachetzki, Addison J. Lana, Elizabeth West, Christine Hong, Jordan DuGal, Yi Zhou, Benjamin C. Li, Payam A. Saisan, Nathanael J. Spann et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
22. Context-dependent regulatory variants in Alzheimer’s disease
    Ziheng Chen, Yaxuan Liu, Ashley R. Brown, Heather H. Sestili, Easwaran Ramamurthy, Xushen Xiong, Dmitry Prokopenko, BaDoi N. Phan, Lahari Gadey, Robert van de Weerd et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
23. Glial changes and gene expression in Alzheimer's disease from snRNA-Seq and spatial transcriptomics
    Songren Wei, Chenyang Li, W.Q. Li, Fumiao Yuan, Jingjing Kong, Xi Su, Peng Huang, Hongbo Guo, Jiangping Xu, Haitao Sun · 2025 · Journal of Alzheimer s Disease
24. Single-cell elderly blood–CSF atlas implicates peripherally influenced immune dysregulation in normal pressure hydrocephalus
    Phan Q. Duy, Emre Kiziltug, Ana B.W. Greenberg, Neel H. Mehta, Le T. Hao, Carla Fortes, Susan Mullany, Baojian Fan, Ani W Manichaikul, Andrew F. Teich et al. · 2025 · Proceedings of the National Academy of Sciences
25. White matters arising: Rethinking Alzheimer’s disease through the lens of myelin
    Constanze Depp · 2025 · Science
26. Multimodal approach to characterize surgically removed epileptogenic zone from patients with focal drug‐resistant epilepsy: From operating room to wet lab
    Jenni Kyyriäinen, Adriana Della Pietra, Mastaneh Torkamani‐Azar, Mireia Gómez‐Budia, Polina A. Abushik, Nataliia Novosolova, Henri Eronen, Omar Narvaez, Ekaterina Paasonen, Vera Lezhnyova et al. · 2025 · Epilepsia Open
27. Comprehensive Multimodal and Multiscale Analysis of Alzheimer’s Disease in 5xFAD Mice: Optical Spectroscopies, TEM, Neuropathological, and Behavioral Investigations
    Dhruvil Solanki, Ishmael Apachigawo, Sazzad Khan, Santanu Maity, Fatemah Alharthi, Samia Nasim, Mohammad Alizadeh Poshtiri, Fnu Sweety, Jianfeng Xiao, Mohammad Moshahid Khan et al. · 2025 · International Journal of Molecular Sciences
28. Utilisation of Machine Learning Approaches Improves RNA-Seq Transcriptome Analyses in Alzheimer’s Disease Brain
    Yuning Cheng, Kristina Santucci, Yulan Gao, Konii Takenaka, Grace Lindner, Si-Mei Xu, Michael Janitz · 2026 · Journal of Molecular Neuroscience
29. Aberrant mRNA splicing and impaired hippocampal neurogenesis in Grin2b mutant mice
    Zohreh Farsi, Ally A. Nicolella, Sean Simmons, Wangyong Shin, Muwon Kang, Gina Lee, Min Jee Kwon, Kira S. Brenner, Inès Picard, Nate Shepard et al. · 2026 · iScience
30. Srrm2 haploinsufficiency drives SynGAP-γ reduction, Agap3 mis-splicing, and oligodendrocyte deficits in a genetic mouse model of schizophrenia
    Sameer Aryal, Chuhan Geng, Margaret A. Yin, Min Jee Kwon, Zohreh Farsi, Nathaniel Goble, Ahmet S. Asan, Kira S. Brenner, Nate Shepard, Ana Geller et al. · 2026 · Cell Reports
31. The bidirectional effects of APPswe on the osteogenic differentiation of MSCs in bone homeostasis by regulating Notch signaling
    Nan Wang, Xiaoyu Shen, Huakun Huang, Runhan Zhao, Habu Jiwa, Zongxin Li, Pei Li, Jixing Ye, Qiang Zhou · 2024 · Genes & Diseases
32. Evolutionary neurogenomics at single-cell resolution
    Emre Caglayan, Geneviève Konopka · 2024 · Current Opinion in Genetics & Development
33. Sonic Hedgehog Is an Early Oligodendrocyte Marker During Remyelination
    Mariagiovanna Russo, Amina Zahaf, Abdelmoumen Kassoussi, Ariane Sharif, Hélène Faure, Élisabeth Traiffort, Martial Ruat · 2024 · Cells
34. Lower expression of BIN1's neuronal isoform in vulnerable excitatory neurons increases risk in Alzheimer's disease
    Rajesh Ranganathan, Siwen Li, Georgy Sapozhnikov, Shoutang Wang, You‐Qiang Song · 2025 · Journal of Alzheimer s Disease Reports
35. Tau alters global gene expression affecting chromatin in the early stages of Alzheimer’s disease
    Giacomo Siano, Martina Varisco, Marco Terrigno, C. Wang, Marco Groth, Marie‐Christine Galas, Jeroen J.M. Hoozemans, Alessandro Cellerino, Antonino Cattaneo, Cristina Di Primio · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
36. A single-cell eQTL atlas of the human cerebellum reveals vulnerability of oligodendrocytes in essential tremor
    Guy Armand Rouleau, Charles-Etienne Castonguay, Farah Aboasali, Miranda Medeiros, Théodore Becret, Zoe Schmilovich, Anouar Khayachi, Alex H. Rajput, Patrick A. Dion · 2024 · Research Square
37. Muti-omics characterization reveals brain-wide disruption of synapses and region- and age-specific changes in neurons and glia in Sp4 mutant mice, a genetic model of schizophrenia and bipolar disorder
    Min Jee Kwon, Kira A. Perzel Mandell, Sameer Aryal, Chuhan Geng, Ally A. Nicolella, Antia Valle-Tojeiro, Sahana Natarajan, Deeksha Misri, Alyssa Hall, Bryan J. Song et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
38. Cell-type specific profiling of human entorhinal cortex at the onset of Alzheimer’s disease neuropathology
    Patricia Rodriguez‐Rodriguez, Wei Wang, Christina Tsagkogianni, Irena Feng, Ana Morello-Megias, Kaahini Jain, Vilma Alanko, Han Ali Kahvecioglu, Elyas Mohammadi, Xiaofei Li et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
39. Comparing phenotypic manifolds with Kompot: Cluster-free differential expression at single-cell resolution
    Dominik J. Otto, Erica A. Arriaga-Gomez, Elana Thieme, Ruijin Yang, Stanley Chun-Wei Lee, Manu N. Setty · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
40. Ketone body β-hydroxybutyrate restores neuronal Tau proteostasis via ketolysis-independent mechanism
    Leigh-Ana M. Rossitto, Jamie Foo, Julia M Di Silvestri, Leanne M Lehmann, Melina Brunelli, Yuhang Nie, Daniel Muñoz-Mayorga, Qiang Xiao, Anna Y Dai-Liu, Suborno Jati et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
41. Multiregional single-cell profiling reveals shared and specialized cellular vulnerability in Alzheimer’s disease
    Kyle J. Travaglini, Mariano I. Gabitto, Yi Ding, Anamika Agrawal, Nadia O. Postupna, Joseph T. Mahoney, Eitan S Kaplan, Erica J. Melief, Jeff Goldy, Anish Bhaswanth Chakka et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
42. Enhanced differentiation of neural progenitor cells in Alzheimer’s disease into vulnerable immature neurons
    Joonho Cho, Simsung Bae, Juyeong Jeon, Janis Lisa Transfeld, Changyeob Lee, Alexi Nott, Fan Gao, Jinsoo Seo · 2025 · iScience
43. Precision medicine in the pediatric and neonatal intensive care units through genomics
    Phan Q. Duy, Benjamin Dylik, Engin Deniz · 2025 · Current Opinion in Pediatrics
44. Identification of Novel Biomarkers Related to Vesicle Trafficking in Alzheimer’s Disease Using Bioinformatics Approaches
    Yirong Hu, Yi Liu, Qiuyan Zhu, Yong Chen, Ying Zeng · 2025 · Neurochemical Research
45. Gene module-trait network analysis uncovers cell type specific systems and genes relevant to Alzheimer's Disease
    Kátia de Paiva Lopes, Ricardo A. Vialle, Gilad Green, Masashi Fujita, Chris Gaiteri, Vilas Menon, Julie A. Schneider, Yanling Wang, Philip L. De Jager, Naomi Habib et al. · 2025 · Acta Neuropathologica Communications
46. Machine Learning-Enhanced Hyperspectral Raman Imaging for Label-Free Molecular Atlas of Alzheimer’s Brain
    Ziyang Wang, Jeewan C. Ranasinghe, Dennis C. Y. Chan, Ashley Gomm, Rudolph E. Tanzi, Can Martin Zhang, Nanyin Zhang, Shengxi Huang · 2025 · ACS Applied Materials & Interfaces
47. Astrocytic TPK1 mitigates amyloid pathology via TFEB-mediated endocytosis
    Shu-Zhen Zhang, Yuan Ma, Yu Ding, Yanqing Yin, B. Wang, Gang Hu, Jia-Wei Zhou · 2026 · Experimental Neurology
48. Systems genetic dissection of brain gene expression reveals excitotoxic mechanisms of Alzheimer’s disease
    Pinghan Zhao, Omar El Fadel, Anh Le, Carl Grant Mangleburg, Justin S. Dhindsa, Timothy Wu, Jinghan Zhao, Meichen Huang, Bismark Kojo Amoh, Aditi Sai Marella et al. · 2026 · Molecular Psychiatry
49. PROTAC-mediated multi-target protein degradation in Alzheimer's disease: mechanistic insights, therapeutic applications, and translational challenges
    Bin Wang, Yunan Li, Tingting Yao, Xinai Shen, Huan Li, Wei Jiang, Xinuo Li, Zheying Zhu · 2026 · RSC Medicinal Chemistry
50. Phagocytosis and neuroinflammation: orchestrating central nervous system homeostasis, repair, and the resolution of inflammation
    Andrew D. Gaudet, Laura K. Fonken · 2026 · Trends in Neurosciences
51. RNA isoform diversity, splicing variants and switching in single cells of the Alzheimer’s disease brain
    Anis Shahnaee, Christine S. Liu, Tony Ngo, Carter R. Palmer, Derya Ziomek, Chris Sin Park, Valerie P. Tan, Natalia Arango Jimenez, Jerold J. M. Chun · 2026 · Communications Biology
52. Decoding neurodegeneration one cell at a time
    Olivia Gautier, Thao P. Nguyen, Aaron D. Gitler · 2026 · Journal of Clinical Investigation
53. Single-cell expression QTL analyses of the human cerebellum reveal vulnerability of oligodendrocytes in essential tremor
    Charles-Etienne Castonguay, Farah Aboasali, Miranda Medeiros, Paria Alipour, Kate Bornais, Théodore Becret, Zoe Schmilovich, Anouar Khayachi, Alex H. Rajput, Patrick A. Dion et al. · 2026 · Nature Genetics
54. Microelectrode array scaled for human hippocampal slices
    Anssi Pelkonen, Vera Lezhnyova, Tomi Ryynänen, Joose Kreutzer, Valeriia Sitnikova, Mireia Gómez‐Budia, Adriana Della Pietra, Antonios Dougalis, Jenni Kyyriäinen, Mastaneh Torkamani‐Azar et al. · 2026 · Epilepsia Open
55. Dissecting microglial contributions to neurodegenerative disease pathophysiology using human pluripotent stem cells
    Dayoung Kim, Takayuki Kondo, Haruhisa Inoue · 2026 · Stem Cell Reports
56. Advances in hiPSC ‐Derived Brain Organoids as a Model to Study Neuroinflammation in Alzheimer's Disease
    Esther M. A. Maciel, Nathalia Costa Silva, Luiz Gustavo Pontes Santos, Fabiola Mara Ribeiro · 2026 · Journal of Neurochemistry
57. The mitochondria-synapse axis in Alzheimer’s disease: Lost coordination in early stages
    Priyanshu Sharma, Navneet Kaur, Nandini Vasal, Kusum Solanki, Aditya Sunkaria · 2026 · Ageing Research Reviews
58. Microglial state transitions are constrained by developmental and metabolic checkpoints
    Adil El Mesaoudi, Dong Won Kim · 2026 · Frontiers in Cellular Neuroscience
59. From the brain cell atlas to precision neurology: a review of the application of AI-driven multi-omics in brain science
    Youzhe He, Yanrong Wei, Jingxi Zhi, C J Huang, Lei Han, Shiping Liu, Lifang Wang · 2026 · GigaScience
60. Single-cell multiomics connects 3D genome and transcriptome alterations in Alzheimer’s disease
    Yang Zhang, Xinyue Lu, Alexander K. Kunisky, Shahul Alam, Junjie Tang, Ruochi Zhang, Shike Wang, H H Zhang, Jude K. Baroudi, Walid Ichcho et al. · 2026 · Science
61. Isotopic Tracing of [13C6] scyllo -Inositol Uncovers Its Incorporation into Phosphatidylinositols in Immortalized Mammalian Cells
    M. K. P. Amma, Laxmikanth Kollipara, Tobias Dürr‐Mayer, Josefin Streeck, Peter Schmieder, Adolfo Saiardi, Henning Jacob Jessen, Sven Heiles, Dorothea Fiedler · 2026 · ACS Chemical Biology
62. Navigating the Molecular Maze of Alzheimer’s Disease: Developing A Human Hippocampal Atlas to Bridge Discovery and Clinical Practice
    Pan Wang, Lifang Wang, Quyuan Tao, Zhen Guo, Ting Luo, Zhi Ping Xu, Youzhe He, Jiayi Yu, Yuyang Liu, Zihan Wu et al. · 2023 · medRxiv
63. Multiomic foundations of human prefrontal cortex tissue function
    Brian Harris Kopell, Deepak A. Kaji, Lora E. Liharska, Eric Vornholt, Alissa A. Valentine, Anina N. Lund, Alice Hashemi, Ryan C. Thompson, Terry M. Lohrenz, Jessica Johnson et al. · 2024 · medRxiv
64. Early amyloid spine response and impaired synaptic transmission of pyramidal neurons in human biopsies with Alzheimer’s Disease-related pathology
    Antonios Dougalis, Polina A. Abushik, Anssi Pelkonen, Luca Giudice, Mireia Gómez‐Budia, Nataliia Novosolova, Nelli‐Noora Välimäki, Mohammad Rezaie, Dilyara Nurkhametova, Raisa Giniatullina et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
65. Powerful and accurate case-control analysis of spatial molecular data
    Yakir Reshef, Lakshay Sood, Michelle L. Curtis, Laurie Rumker, Daniel J. Stein, Mukta G. Palshikar, Saba Nayar, Andrew D. Filer, Anna Helena Jonsson, Ilya Korsunsky et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
66. Compensatory Plasticity Defines a Vulnerable Neuronal State in Alzheimer’s Disease with Psychosis
    Matheus B. Victor, Na Sun, Kyriaki Galani, Noelle Leary, Yosuke Tanigawa, Aine Ni Scannail, Li‐Lun Ho, Shaniah Prosper, Liwang Liu, Julia Kofler et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
67. Reconstructing developmental and disease progression with sample-level embeddings
    Longda Jiang, Zhixin Cyrillus Tan, Isabella N. Grabski, Yuhan Hao, Nathan J. Nakatsuka, Sourav Sarkar, Anagha Shenoy, Rahul Satija · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
68. The contribution of oligodendrocytes to amyloid and tau pathologies in mouse models of Alzheimer’s disease
    Andrew Octavian Sasmita · 2024 · eDiss (Georg-August-Universität Göttingen)
69. Neuron migration to brain regions key to memory and navigation continues into childhood
    2024 · Nature
70. A thorough analysis of the molecular mechanisms underlying the protein changes in the human cerebral cortex affected by Alzheimer's disease
    Hai Duc Nguyen, Giang Huong Vu, Woong‐Ki Kim · 2024 · Gene Reports
71. Early trajectory of Alzheimer’s tracked in single-cell brain atlases
    Angie Voyles Askham · 2024 · The Transmitter
72. Cytokine-induced reprogramming of human macrophages toward Alzheimer’s disease-relevant molecular and cellular phenotypes in vitro
    Anna Podleśny-Drabiniok, Carmen Romero-Molina, Tulsi Patel, Yi-See Wen, Yi-Yuan Liu, E. Marcora, A. Goate · 2024 · bioRxiv
73. Single-nucleus epigenomic dysregulation unmasks genetic risk-associated neurodegenerative glia states
    Xia Han, Gregory M. Rosenberg, Vivianne M. Kisling, Tao Zhang, Chia‐Yi Lee, Ashvin Ravi, Mikhail Melnik, Tina Bilousova, Salvatore Spina, Alissa L. Nana et al. · 2026 · Nature Communications
74. Molecular pathogenesis of Alzheimer's disease onset in a mouse model: effects of cannabidiol treatment
    Mary A. Bishara, Phoebe P. Chum, Fritz E. L. Miot, Ankita Hooda, Richard E. Hartman, Erik J. Behringer · 2025 · Frontiers in Neuroscience
75. Gene expression changes in human brain evolution
    Stefano Berto, Soojin V. Yi, Geneviève Konopka · 2025 · Elsevier eBooks
76. Discovery of disease-associated cellular states using ResidPCA in single-cell RNA and ATAC sequencing data
    Shaye Carver, Kodi Taraszka, Stefan Groha, Alexander Gusev · 2025 · Human Genetics and Genomics Advances
77. Neuronal subtype-specific metabolic changes in neurodegenerative and neuropsychiatric diseases predicted via a systems biology-based approach
    Boyu Jiang, Shuang Wang, Junkai Xie, Hyunjin Kim, Anke M. Tukker, Juexin Wang, Aaron B. Bowman, Chongli Yuan, Priyanka Baloni · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
78. Single-cell Spatial Transcriptional Profiling Uncovers Heterogeneous Cellular Responses to Pathogenic Tau in a Mouse Model of Neurodegeneration
    Xuehan Sun, Lidan Wu, Timothy C. Orr, Ashley Heck, Kimberly Young, Nathan Dunaway, Jose Ceja Navarro, Joseph Beechem, Miranda E. Orr · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
79. Additional file 1 of Deciphering glial contributions to CSF1R-related disorder via single-nuclear transcriptomic profiling: a case study
    Jie Pan, Jaume Forés-Martos, Claire Delpirou Nouh, Tanner D. Jensen, Kristen Vallejo, Romain Cayrol, Saman Seyed Ahmadian, Euan Angus Ashley, Michael D. Greicius, Inma Cobos · 2024 · Figshare
80. Additional file 3 of Deciphering glial contributions to CSF1R-related disorder via single-nuclear transcriptomic profiling: a case study
    Jie Pan, Jaume Forés-Martos, Claire Delpirou Nouh, Tanner D. Jensen, Kristen Vallejo, Romain Cayrol, Saman Seyed Ahmadian, Euan Angus Ashley, Michael D. Greicius, Inma Cobos · 2024 · Figshare
81. Additional file 4 of Deciphering glial contributions to CSF1R-related disorder via single-nuclear transcriptomic profiling: a case study
    Jie Pan, Jaume Forés-Martos, Claire Delpirou Nouh, Tanner D. Jensen, Kristen Vallejo, Romain Cayrol, Saman Seyed Ahmadian, Euan Angus Ashley, Michael D. Greicius, Inma Cobos · 2024 · Figshare
82. Additional file 5 of Deciphering glial contributions to CSF1R-related disorder via single-nuclear transcriptomic profiling: a case study
    Jie Pan, Jaume Forés-Martos, Claire Delpirou Nouh, Tanner D. Jensen, Kristen Vallejo, Romain Cayrol, Saman Seyed Ahmadian, Euan Angus Ashley, Michael D. Greicius, Inma Cobos · 2024 · Figshare
83. Additional file 2 of Deciphering glial contributions to CSF1R-related disorder via single-nuclear transcriptomic profiling: a case study
    Jie Pan, Jaume Forés-Martos, Claire Delpirou Nouh, Tanner D. Jensen, Kristen Vallejo, Romain Cayrol, Saman Seyed Ahmadian, Euan Angus Ashley, Michael D. Greicius, Inma Cobos · 2024 · Figshare
84. Novel drug candidate binds to delta subunit containing GABAA receptors and improves spatial memory
    Orsolya Huzián, Lajos István Nagy, Laszlo Hackler, Levente Knapp, Ágnes K. Kocsis, Ildikó Szöts, Gábor Tamás, László Géza Puskás, Gábor Molnár · 2026 · Biomedicine & Pharmacotherapy
85. Temporal single-cell atlas of full-length Huntington’s disease mouse model defines stage-specific signatures of corticostriatal dysfunction
    Ashley B. Robbins, Paul T. Ranum, Icnelia Huerta-Ocampo, Michael Kuckyr, Beverly L. Davidson · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
86. 4,4′-dimethoxychalcone exerts neuroprotective effects in Alzheimer's disease mice by activating the Keap1/Nrf2 signaling pathway
    Shanshan Ma, Qianqian Wang, Wenzhi Yang, Siling Zhang, Feifan Liu, Fangxia Guan, Hongtao Liu, DongPeng Li · 2026 · European Journal of Pharmacology
87. A transcriptional program associated with neurotransmission in the living human brain
    Alexander W. Charney, Lora E. Liharska, Eric Vornholt, Alissa A. Valentine, Anina N. Lund, Alice Hashemi, Ryan C. Thompson, Terry M. Lohrenz, Jessica S. Johnson, Nicole Bussola et al. · 2026 · Molecular Psychiatry
88. Selective weakening of population-coupled synaptic activity in vivo in a mouse model of amyloid-beta pathology
    Leire Melgosa-Ecenarro, Carola I. Radulescu, Nazanin Doostdar, Joe Airey, Francesca A. Chaloner, Nawal Zabouri, Giada Pedretti, Francesca Osso, Leire Garrido Perez, Kjara S Pilch et al. · 2026 · Nature Communications
89. Local co-expression of GLP1R and INS in human cortical interneurons
    Nóra Faragó, Agnes Katalin Kocsis, Sándor Bordé, Ágnes Zvara, Pál Barzó, László Géza Puskás, Gábor Tamás, Éva Csajbók · 2026 · Frontiers in Endocrinology
90. Disrupted lipid homeostasis as a pathogenic mechanism in ABCA7 ‐associated Alzheimer's disease risk
    Younji Nam, Brooke A. DeRosa, Aura María Ramírez, Biniyam A. Ayele, Patrice L. Whitehead, Larry Deon Adams, Charles G. Golightly, Takiyah D. Starks, Mayra Juliana Laverde-Paz, Holly N. Cukier et al. · 2026 · Alzheimer s & Dementia
91. Case Studies and Patents in Alzheimer’s Disease Research
    Deepak Kumar, Piyush Anand, Juhi Tiwari, S. N. Singh · 2026 · BENTHAM SCIENCE PUBLISHERS eBooks
92. Microglia crosstalk with T cells in neurodegenerative diseases: pathogenesis and treatment targets
    G Chen, Cong Zhao, Chun Wang, G Chen, Jingming Shi, Huihui Chen · 2026 · International Immunopharmacology
93. Temporal single-cell atlas of full-length Huntington’s disease mouse model defines stage-specific signatures of corticostriatal dysfunction
    Ashley B. Robbins, Paul T. Ranum, Icnelia Huerta-Ocampo, Michael Kuckyr, Beverly L. Davidson · 2026 · Molecular Neurodegeneration
94. Glymphatic dysfunction and neuroinflammation in FXTAS: evidence from DTI-ALPS and gene expression analysis
    Andrea Elias-Mas, Esther Granell, Cèlia Painous, Marta Rubio‐Roy, Jorge Aguado-Gracia, Emma Muñoz‐Moreno, Alejandro Hinojosa, Iñigo Herrero-Vidaurre, Maria Isabel Alvarez-Mora, Randi Hagerman et al. · 2026 · Frontiers in Molecular Neuroscience
95. Tunable acoustic rotation for deep biophysical phenotyping of preclinical Alzheimer's disease
    Yuxin Wang, Yue Quan, Shizheng Zhou, Yinning Zhou · 2026 · Materials Today Bio
96. Tea-derived natural nanodrug simultaneously enables real-time fluorescent tracking and noninvasive treatment of neuroinflammation in Alzheimer’s disease
    Lulu Qian, Mingyue Cui, Menglin Wu, Bin Song, Pengcheng Wang, Minke Wu, Tongyu He, Baochuan Zhang, Yao He · 2026 · Journal of Nanobiotechnology
97. A diagnostic plasma omics‐biomarker for Alzheimer's disease informed by microglial single‐cell transcriptomics: A pilot study
    Michael William Lutz, Zhaohui Man, Yifei Zheng, Srilakshmi Venkatesan, Ornit Chiba‐Falek · 2026 · Alzheimer s & Dementia Translational Research & Clinical Interventions
98. ABCA7 rs3752231 variant effects on glial responses to amyloid-β and plaque maturation in Alzheimer’s disease
    Marianna Papageorgopoulou, Emily Adair, Nurun Nahar Fancy, Baptiste Avot, Samuel L Boulger, Mara S. Wülfing, Paul McMahan Matthews · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
99. Intrinsic molecular susceptibility underlies selective neuronal vulnerability in the Alzheimer’s disease entorhinal cortex
    Samuel L Boulger, Daniela Lerose, Emily Adair, Marianna Papageorgopoulou, Yinuo Zhao, Baptiste Avot, Michael Thomas, Pavit Nibber, Hannah Klug, Nurun Nahar Fancy et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
100. Reconceptualizing bipolar disorder through an integrative biological lens: synthesis, convergence, and emerging directions
     Yasin Ali Muhammad · 2026 · Frontiers in Integrative Neuroscience