Early Alzheimer’s disease pathology in human cortex involves transient cell states

Gazestani, Vahid, Kamath, Tushar, Nadaf, Naeem M., Dougalis, Antonios, Burris, S.J., Rooney, Brendan, Junkkari, Antti, Vanderburg, Charles, Pelkonen, Anssi, Gomez-Budia, Mireia, Välimäki, Nelli-Noora, Rauramaa, Tuomas, Therrien, Martine, Koivisto, Anne M., Tegtmeyer, Matthew, Herukka, Sanna-Kaisa, Abdulraouf, Abdulraouf, Marsh, Samuel E., Hiltunen, Mikko, Nehme, Ralda, Malm, Tarja, Stevens, Beth, Leinonen, Ville, Macosko, Evan Z.·2023·Cell
DOI 10.1016/j.cell.2023.08.005

Cited by (213)

Items 201–213 of 213

  1. Sequential associations of myelin dysfunction with Aβ and Tau pathology in Alzheimer's disease: a dynamic myelin perturbation
    Jingxiang Wen, Guoyu Lan, Yuan Fu, Weiru Jiang, Bin Xu, Jing Zhang, Alzheimer’s Disease Neuroimaging Initiative · 2026 · Alzheimer s Research & Therapy
  2. SPRY1 suppresses microglial fatty acid oxidation by retaining FATP3 on the endoplasmic reticulum in Alzheimer’s disease
    Yu‐Ge Zhang, Shi-Yao Li, Yi-Zhen Hu, Yi Ding, Yu-Tong Zhang, Huiwen Zhang, Y Zhang, Lu Xu, Zhiyuan Zhang, Lei Li · 2026 · Journal of Neuroinflammation
  3. Enhanced hippocampal miR-32-5p promotes neuronal hyperexcitability and epileptic seizures by targeting KCC2
    Xiaolin Zhong, Ling Chen, Shixi Zhou, Xueqin Liu, 黄艳梅, Yajuan Wang, Yue Liang, Min Chen, Heng Wu, Jianghua Liu et al. · 2026 · European Journal of Pharmacology
  4. Photobiomodulation with 808 nm Laser Light Repairs Mitochondrial Integrity and Normalizes ROS, ATP, and Membrane Depolarization in Aβ-Exposed Primary Neurons in Alzheimer’s Disease Model
    Iuliia Golovynska, Binjun Li, Qinglin Chen, Sergii Golovynskyi, Hao Xu, Yurii V. Stepanov, Liudmyla I. Stepanova, Fangrui Lin, Junle Qu, Tymish Y. Ohulchanskyy · 2026 · International Journal of Molecular Sciences
  5. Scalable joint non-negative matrix factorization for paired single cell gene expression and chromatin accessibility data
    William Geraint Morgans, Andrew D Sharrocks, Mudassar Iqbal · 2026 · NAR Genomics and Bioinformatics
  6. Topoisomerase I inhibition yields a CD74high/MHChigh human microglial subtype with enhanced Aβ uptake
    Verena Claudia Haage, John F. Tuddenham, Natacha Comandante-Lou, Alex R. Bautista, Anna Sophia Monzel, Frankie G. Garcia, Rebecca Chiu, Masashi Fujita, Prabesh Bhattarai, Charles C. White et al. · 2026 · Cell Reports
  7. The Adult Neurogenesis Theory of Alzheimer’s Disease Predicts Where Tauopathy Develops in the Brain
    Carlo Abbate · 2026 · International Journal of Molecular Sciences
  8. When tau goes electric: The first report of a positive correlation between tau burden and ex vivo hyperexcitability in human epileptic hippocampal slices
    Olga Švecová, Michal Hendrych, Eva Zatloukalová, Martina Kolajová, B. Liščáková, Hana Hříbková, Sylva Dvořáková, Petr Klimeš, Eva Brichtová, Milan Brázdil et al. · 2026 · Neurobiology of Disease
  9. Accurate and well-powered case–control analysis of spatial molecular data
    Yakir Reshef, Lakshay Sood, Michelle L. Curtis, Laurie Rumker, Daniel J. Stein, Mukta G. Palshikar, Saba Nayar, Andrew D. Filer, Anna Helena Jonsson, Ilya Korsunsky et al. · 2026 · Nature Methods
  10. Dynamic remodeling of microglial responses in Alzheimer’s disease: heterogeneous states, spatiotemporal progression, and immunometabolic dysregulation
    Simin Han, Shanshan Wang, Jingjing Liu, Xulin Liu, Qinglu Wang, Chang Meng · 2026 · Frontiers in Cell and Developmental Biology
  11. Transitional Neuronal States Suggest Divergent Trajectories of Resilience and Neurodegeneration in an Alzheimer’s Disease Mouse Model
    Yun‐Juan Chang, Philip H. Stavrides, Harshitha Pidikiti, Kyrillos W. Ibrahim, Ju‐Hyun Lee, Martin J. Berg, Kuldeep Singh Sachdeva, Stephen D. Ginsberg · 2026 · Brain Sciences
  12. Celebrating 50 years of translational neuroscience in Kuopio
    Jukka Jolkkonen · 2026 · Neuroprotection/Neuroprotection (Chichester, England. Print)
  13. Microglia in Alzheimer’s disease: from pathogenic mechanisms to therapeutic targeting
    Ling Tang, Xiaoyan Li, Zhao Ran, Zhu-Zhu Qin, Shiyan Chen, Miaomiao Zhang, Linying Zhou, Wenjun Wang, Liang Chen · 2026 · Frontiers in Immunology