Guidelines for minimal information on cellular senescence experimentation in vivo

Cited by (363)

Items 101–200 of 363

1. ALDH1A3 Regulates Cellular Senescence and Senescence-Associated Secretome in Prostate Cancer
   Sen Wang, Lin Wang, Yu Zhao · 2025 · Cancers
2. Synergistic Effects of Activatable Photodynamic Therapy and Crisaborole for Psoriasis through Senolysis and Immunomodulation
   Yangxin Yu, Xucheng Lv, Zhuowei Chen, Xiaokang Li, Liru Chen, Youyou Chen, Wenhui Gu, Xiantao Zhou, Jian Li, Donglei Shi · 2025 · Journal of Medicinal Chemistry
3. Nanomaterial-based strategies for anti-aging and regeneration in oral and maxillofacial tissues: Mechanisms and applications
   Xinjia Cai, Ying-Ying Cui, Chuan-Yang Ding, Hang-Bo Liu, Min Yu, Li-Yuan Chen, Cheng-Ye Ding, Xiaolan Wu, He Zhang, Chang Li et al. · 2025 · Biomaterials
4. Cellular Senescence in Kidney Diseases: From Bench to Clinic
   Shaoqun Shu, Jing Liu, Yuan Qian, Chun Zhang · 2025 · The FASEB Journal
5. Macrophage-derived KIF13B interacts with USP9X to attenuate abdominal aortic aneurysm development by potentiating TFEB stability
   Jing-Xuan Chen, Yi-Tong Xu, Huahui Yu, Yi-Ran Liu, Guo-Lin Miao, Yu-Fei Han, Li-Wen Zheng, Ze-Yu Cai, Zi-Hao Zhou, Jin-Xuan Chen et al. · 2025 · Theranostics
6. Research progress on blood therapy for anti-aging
   Shuguang Liu, Shichun Wang, Yibo Dong, Shichao Yang, Chunyan Yao · 2025 · Journal of Advanced Research
7. Growth hormone excess drives liver aging via increased glycation stress
   Parminder Pal Singh, Anil K. Gautam, Marissa N. Trujillo, Praveen Singh, Lizbeth Enriquez Najera, James J. Galligan, Lisa E. Hensley, Pankaj Kapahi, Andrzej Bartke · 2025 · Aging
8. Cellular Senescence Contributes to Colonic Barrier Integrity Impairment Induced by Toxoplasma gondii Infection
   Yingting Huang, Yumeng Zhou, Zhicheng He, Jiayi Yang, Jianqi Gu, Bingqian Cui, Siyu Li, Heng Deng, Wendi Zhao, Xiaoying Yang et al. · 2025 · Inflammation
9. Promoting the nuclear retention of HMGB1 attenuates astrocyte senescence
   N. Zhang, Fan Yang, Junyu Shi, Xuhuan Tang, Anqi Fan, Wenhua Li, Feng Zhang, Shuaishuai Chai, Qun Chen, Chenchen Wang et al. · 2026 · Journal of Neuroinflammation
10. Cell Type‐Specific Expression of p16, p21, and p53 Reveals Age‐Dependent Glial Senescence in the App NL‐G‐F Mouse Model of Alzheimer's Disease
    Eileen Mac Sweeney, Giulia Abate, Bjorn R. V. Bakker, Andrea Mastinu, Ylenia Lai, Daniela Letizia Uberti, Per Nilsson, Simone Tambaro · 2026 · Aging Cell
11. Senescence Modulation: An Applied Science Review of Strategies in Anti-Aging, Regenerative Aesthetics, and Oncology Therapy
    Steven Januar Kusmanto · 2025 · Current Issues in Molecular Biology
12. Implications of cellular senescence in Parkinson’s disease: Recent developments and future directions
    Julie Kay Andersen · 2026 · Current Opinion in Neurobiology
13. Activated Protein C Suppresses Cardiomyocyte Senescence in Diabetic Cardiomyopathy via PAR1/PAR3-P85-CaMKIIδ Axis
    Yueqi Zhang, Lei Dai, Mengwen Wang, Xiaodan Zhong, Xiaolei Liu, Kaiyue Zhang, Lingyun Luo, Lingyun Wang, Wei Dong, Alexandra Váczy et al. · 2025 · Diabetes
14. Persistent and transient senescent cells contribute to brain-barrier development
    Lauren Ashley Watson, Zoe Adelsheim, Mackenzie J. Carter, Grace T. Carter, Karen L. Jimenez-Reyes, Huijie Du, Ziqing Zhu, David B. Berry, Mia C. Paredez, Rania H. Palaniappan et al. · 2026 · Cell
15. Immunosuppressive macrophages determine the effect of cellular senescence on tumor progression
    Marta Lalinde-Gutiérrez, Sandra Pérez‐Ramos, Verónica Rodilla, Pau Garcia-Baucells, Perera-Bel Julia, Pau Berenguer‐Molins, Lara Nonell, Irene Agustí-Barea, Christopher George Mueller, Joaquı́n Arribas · 2026 · Science Advances
16. Molecular engineering development of β-galactosidase-activatable fluorogenic probes for precise senescence tracking in cells, tissues and a mouse model of psoriasis
    Xinhang Lv, Yangxin Yu, Zhuowei Chen, Guangwei Wang, Xiaokang Li, Lingyu Wu, Lingyu Wu, Jiale Wu, Jian Li, Yuan Guo et al. · 2025 · Sensors and Actuators B Chemical
17. Proinflammatory Macrophage-Targeted Nanoparticles Rejuvenate Aged Macrophages and Their Phagocytic Capacity
    Donglin Cai, Zhelun Li, Wendong Gao, Jiaying Liu, Xiaying Qi, Jie Jin, Yufeng Zhang, Qing Zhang, Lan Xiao, Yin Xiao · 2025 · ACS Nano
18. Comparative phenotypic and molecular profiling of replicative and chemically-induced senescence in articular chondrocytes
    Maria Belen Arteaga, K. V. Tarasova, Angkana Kidtiwong, Sinan Gültekin, Iris Gerner, Florien Jenner · 2026 · Cell Death Discovery
19. The mitochondrial and cytoplasmic superoxide anion imbalance trigger the expression of certain cellular aging markers in HaCaT keratinocytes
    Nathália Cardoso de Afonso Bonotto, Ivana Beatrice Mânica da Cruz, Bárbara Osmarin Turra, Ana Laura Kerkhoff Escher, Fernanda dos Santos Trombini, Juerg Zimmermann, Verônica Farina Azzolin, Micheli Mainardi Pillat, Euler Esteves Ribeiro Filho, Fernanda Barbisan · 2024 · Biogerontology
20. Uncovering the transcriptional hallmarks of endothelial cell aging via integrated single-cell analysis
    Sarah Dobner, Lisa Kleißl, Fanni Tóth, Robert L. Paxton, Irena Yordanova, Kveta Brazdilova, Cedric Vanluyten, Aleksandra Aizenshtadt, Hanna Toth, Jake Burton et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
21. Spatiotemporal decoding of skin biology: development, aging, disease, and regeneration
    Ding Xi, R. Stephanie Huang, Yixu Li, Zhaofan Xia, Shizhao Ji · 2026 · Burns & Trauma
22. Quercetin-loaded milk-derived extracellular vesicles for the treatment of inflammatory bowel disease by alleviating senescence-associated cell cycle arrest
    Runrun Wan, Tingting Cao, Meng Deng, Cheng-Biao Hu, Caixiao Liu, Yijuan Han, Na Zhao, Qiaoning Wang, Xueru Li, Xiangdong Wang et al. · 2025 · Chemical Engineering Journal
23. O-GlcNAcylation drives macrophage IL-4 responsiveness and tissue residency through metabolic and cell cycle calibration
    Graham A. Heieis, Conor M. Finlay, Thiago A. Patente, Martina Erbì, Thijs van der Meer, Jordan O'Keeffe, Joost M. Lambooij, Frank Otto, Frank G. A. Faas, Aat A. Mulder et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
24. Characterizing the SASP ‐Dependent Paracrine Spreading of Senescence Between Human Brain Cell Types
    Taylor Russo, Markus Rießland · 2026 · Aging Cell
25. Cellular senescence in cancer: Friend or fraud?
    Qingxin Chen, Jianxin Liu, Jianming Wu, Xin Xiang, Xiaogang Zhou, Jianing Mi, Jing Wei, Xiao Zou, Anguo Wu · 2026 · Drug Resistance Updates
26. Senescence as a Driver of Smooth Muscle Cell Plasticity and Atherosclerosis: Mechanisms and Therapeutic Opportunities
    Lisa Steegen, Mandy O. J. Grootaert · 2026 · Cells
27. Senescent Cell Clearance Ameliorates Temporal Lobe Epilepsy and Associated Spatial Memory Deficits in Mice
    Tahiyana Khan, David J. McFall, Abbas I. Hussain, Logan A. Frayser, Timothy P. Casilli, Meaghan C. Steck, Irene Sánchez-Brualla, Noah M. Kuehn, Michelle Cho, Jacqueline A. Barnes et al. · 2025 · Annals of Neurology
28. Circular Single‐Stranded DNA‐Based Artificial Nanoviruses Mitigate Colorectal Cancer Development
    Jinghao Wang, Pengfei Zhang, Yonglian Huang, Guang Hu, Kexuan Zou, Songtao Zhou, Dandan Shao, Jianming Wang, Jie Song · 2025 · Small Methods
29. Targeting senescent cells in aging and COVID-19: from cellular mechanisms to therapeutic opportunities
    Yu Lai Yuan, Kaixuan Lin, Haoyu Wu, Mingli Hu, Xuejie Yang, Jie Wang, Johannes Grillari, Jiekai Chen · 2024 · Cell Regeneration
30. Variable Expression of Oncogene-Induced Senescence/SASP Surrogates in HPV-Associated Precancerous Cervical Tissue
    Tareq Saleh, Nisreen M. Himsawi, Amani Al Rousan, Ahmad Alhesa, Mohammed El‐Sadoni, Suzan Khawaldeh, Nisreen Abu Shahin, Ala’ Abu Ghalioun, Bayan Shawish, Kholoud Friehat et al. · 2024 · Current Issues in Molecular Biology
31. Intestinal T cells in aging: implications for gut barrier integrity and inflammaging
    Christina M. Stevens, Cecilia R. Schaaf, Theodore M. DeConne, Kylie Kavanagh · 2026 · GeroScience
32. Mitochondrial priming in therapy-induced senescence: implications for CAR-T/NK immunosenolytic therapy
    Javier Abel Menéndez, Ruth Lupu, Begoña Martı́n-Castillo, Josep Sardanyés A, Tomás Alarcón, Sara Verdura, Elisabet Cuyàs · 2025 · Frontiers in Immunology
33. Senotherapeutics: Milestones, innovations, and future prospects
    Erdem Atasever, Mehmet Can Atayik, Ufuk Çakatay · 2025 · Advances in pharmacology
34. Expression of Tetraspanin 4 Relative to Therapy-induced Senescence Markers in Breast Cancer in Response to Neoadjuvant Chemotherapy
    Tareq Saleh, Sofian Al Shboul, Kholoud Friehat, Nebras Y. Melhem, Alia H. Al-Mohtaseb, Samah O. Al-Omari, Mohammad Matalka, Nisreen Abu Shahin, Shrouq Daromar, Ahmad Alhesa et al. · 2025 · Journal of Histochemistry & Cytochemistry
35. Regulatory mechanisms of age-related degenerative diseases: Insights from the gut microbiota-cellular senescence interaction network
    Peng Sun, Guannan Chen, Yilan Guo · 2026 · Ageing Research Reviews
36. Reduced fertility induced by MASLD in female mice is improved by senolytic treatment
    Jéssica D. Hense, José V.V. Isola, Driele Neske Garcia, Bianka M. Zanini, Juliane B. Prosczek, César Augusto Pinzón Osorio, Camila de Brito, Samin A Mondal, Heather C. Rice, RODRIGO A. VAUCHER et al. · 2026 · Biology of Reproduction
37. A Prominent Pro‐Inflammatory Phenotype Is Observed in Replication and Stress‐Induced Senescent Mast Cells
    Alfredo Ibarra-Sánchez, Iris Karina Madera-Salcedo, D. Esparza‐Reyes, P. Mendoza‐Montiel, J. Padilla, Claudia González‐Espinosa · 2025 · Aging Cell
38. Identification of markers for neurescence through transcriptomic profiling of postmortem human brains
    Shiva Kazempour Dehkordi, Sogand Sajedi, Amirreza Heshmat, Miranda E. Orr, Habil Zare · 2025 · npj Aging
39. p16 Ink4a ‐Positive Hepatocytes Drive Liver Fibrosis Through Activation of LIFR Family Pathway
    Koji Nishikawa, Teh‐Wei Wang, Satoshi Kawakami, Shota Tanimoto, Kiyoshi Yamaguchi, Taketomo Kido, Masamichi Kimura, Tsunekazu Hishima, Yuki T. Okamura, Satotaka Omori et al. · 2026 · Advanced Science
40. Expression of angiogenic factors in the mammalian senescent cell sustaining Trichinella spp. muscle larvae
    Magdalena Dąbrowska, Agnieszka Kępczyńska, Katarzyna Goździk, Natalia Nowak, Łukasz Stanisław Uram, Marek Skoneczny, Maria Doligalska, Ewa Sikora · 2025 · Histochemistry and Cell Biology
41. Overactivation of Cdc42 GTPase Impairs the Cytotoxic Function of NK Cells From Old Individuals Towards Senescent Fibroblasts
    Albert Kallon Koroma, Karmveer Singh, Yongfang Wang, Linda Krug, Philipp Haas, Meinhard Wlaschek, Vadim Sakk, Tanja Schuster, Daniel E Furst, Hubert Schrezenmeier et al. · 2026 · Aging Cell
42. SIRT1 regulates dermal fibroblast senescence via impaired deacetylase function and mitochondrial dysfunction during skin aging induced by chronic oral cadmium exposure
    2026
43. Senescence Programs Shape the Chronic Wound Microenvironment
    Maria Shvedova, Minsung Cho, Jeroen Eyckmans, Danny S. Roh · 2026 · Advances in Wound Care
44. Impact of Cellular Senescence on LCN2 Expression in Salivary Gland Epithelial Cells and Oral Keratinocytes
    Yosuke Shikama, Kayo Yoshida, Yuka Shikama · 2026 · BioFactors
45. Isorhamnetin Alleviates Renal Fibrosis Induced by Renal Tubular Epithelial Cell Senescence Via Inhibition of the IL‐6/IL‐6R Signaling Pathway
    Weifei Liang, Xiangqiu Chen, Tao Wu, Xichun Zheng, Shaohua Zeng, Qingchun Zhou, Wen Ma, Hao Lin, Donglin Sun · 2026 · iMetaMed
46. New insights in cellular senescence: The pituitary model
    Florencia Herbstein, Josefina Rosmino, Mirtha Adriana Guitelman, Joaquina Cagliero, David Gonilski‐Pacin, Nicolas Ciancio del Giudice, Manuel Fiz, Mariana Fuertes, EDUARDO S. ARZT · 2025 · Journal of Neuroendocrinology
47. A recently evolved domain of the human ING1 epigenetic regulator targets mitochondria and induces senescence
    Jessica Bertschmann, Grace Liu, Mahbod Djamshidi, Katy Heshmatazad, Yury Romanov, Jasleen Dhaliwahl, Hamed Hojjat, Yang Yang, A. P. Jason de Koning, Karl T. Riabowol et al. · 2026 · Cellular and Molecular Life Sciences
48. An Improved Human 3-Dimensional Skin Model for Aging Research
    Sebastian Huth, Yvonne Marquardt, Laura Huth, Karmveer Singh, Karin Scharffetter‐­Kochanek, Jens Malte Baron, Pallab Maity · 2025 · Journal of Investigative Dermatology
49. Senescent Schwann cells as therapeutic targets in nerve regeneration and peripheral neuropathies
    Daniela L. Rebolledo, Maaz Khan, Simon Melov, Ahmet Höke, Felipe A. Court · 2026 · Trends in Molecular Medicine
50. Restored clearance of senescent neutrophils by tissue-resident macrophages limits organ aging
    Yuting Jessy Tan, Travis E. Conley, Fuwen Yao, Fernando Jose Garcia-Marques, Damilola Emmanuel Akinyemi, Van Vuong Dinh, Qian Wang, Abel Bermudez, Jieun Kim, Julia A. Belk et al. · 2026 · Science
51. Communication breakdown: senescent cells in interorgan communication of aging
    Rituparna Banik Ghosh, Shweta S. Dipali, Gabriela Desdín-Micó, Matthew J. Yousefzadeh · 2026 · Trends in Endocrinology and Metabolism
52. Chronic stress induces senescence build-up early in life
    Victor Z. Lau, Ifeoluwa Oluleke Awogbindin, Marie‐Ève Tremblay · 2025 · Nature Aging
53. Connectivity Map and perturbation-based sensitivity analysis identifies MEK inhibitors as senolytics in human lung fibroblasts
    Amirhossein Nayeri Rad, Simon Sperger, Leigh Matthew Marsh, Konrad Höetzenecker, Ingo Lämmermann, Johannes Grillari · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
54. Cortactin Suppresses mTOR-Dependent Senescence in Circulating Tumor Cells
    Jianyang Hu, Binyu Zhang, Junhao Chen, Guanyin Huang, Mao Zhao, Hongchao Zhou, Fan Yang, Ke Liu, Shuqian Zheng, Haoyuan Tan et al. · 2025 · Cancer Research
55. Profiling the molecular and physiological effects of senolytic treatment on aged mice identifies immune, fibrotic and metabolic remodeling
    Jing Hou, Kai-Xuan Chen, Qiao-Ni Xiao, Chen Hu, Jie Wei, Yang-Zi Jiang, Ling Liu, Chen He, Mei Huang, Yurui Jiao et al. · 2026 · Nature Aging
56. Altered Expression of Cell Cycle Regulators and Factors Released by Aged Cells in Skeletal Muscle of Patients with Bone Fragility: A Pilot Study on the Potential Role of SIRT1 in Muscle Atrophy
    Angela Falvino, Roberto Bonanni, Beatrice Gasperini, Ida Cariati, Angela Chiavoghilefu, Amarildo Smakaj, Virginia Veronica Visconti, Annalisa Botta, Riccardo Iundusi, Elena Gasbarra et al. · 2025 · Biomedicines
57. Accelerated senescence animal models and application in dentistry: A scoping review
    Siwei Wang, Jia-Yu Mou, Jia-Rui Jiang, Qi He, Mulan Qahar, Daniele De Santis, Fang Qi, Guang-Chao Xu, Jian-Guo Liu · 2025 · Journal of Dental Sciences
58. Repurposing the plant-derived compound apigenin for senomorphic effect in antiaging pipelines
    Hongwei Zhang, Qixia Xu, Zhirui Jiang, Rong Sun, Sanhong Liu, James L. Kirkland, Weidong Zhang, Yu Sun · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
59. Colchicine in cardiovascular medicine: Current perspectives on mechanisms and clinical therapeutics
    Huanyu Ding, Chak Kwong Cheng, Minchun Jiang, Xiang Cheng, Yu Huang · 2026 · Pharmacology & Therapeutics
60. Di-n-butyl phthalate induces NF-κB-mediated senescence-associated secretory phenotype to promote epithelial proliferation, epithelial-mesenchymal transition, and benign prostatic hyperplasia
    Tiewen Li, Yichen Zhang, Xuehao Zhou, Shiyu Ji, Zeng Zhou, Wenhao Wang, Luheng Shen, Hengrui Liu, Zhiwen Xie, Yuan Ruan · 2026 · Environment International
61. SRSF3 knockdown-induced cellular senescence as a possible therapeutic strategy for non-small cell lung cancer
    2025
62. Pre‐Encoded IFN‐I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors
    Andrew Nguyen, Scott R. Walsh, Li Deng, Lan Chen, Yonghong Wan · 2025 · Advanced Science
63. Glucocorticoid impairs angiogenesis-dependent osteogenesis by downregulating EphB4 in endothelial cells.
    Qing-Hua Ren, Xing Rong, Ting Liu, Zhi-Chao Zhang, Wei-Dong Zhang, Hong-Rui Liu, Shibing Guan, Min-Qi Li · 2025 · Biochemical Pharmacology
64. Microglial senescence and epigenetic reprogramming in alzheimer's disease: An immunometabolic perspective
    Jinye Ma, Baiqi Yang, Xuefan Jiang, Luping Wang, Wei Wei, Yu Cao, Hao Li · 2026 · Experimental Gerontology
65. Cellular senescence in skeletal muscle: myogenic and nonmyogenic cell populations, mechanisms, and therapeutic opportunities
    Κωνσταντίνος Παπανικολάου, Angad Yadav, Robert T. Mankowski, Matthew S. Alexander, Jorge Luis Gamboa, Anna Elizabeth Thalacker‐Mercer, Cory M. Dungan, Davis A. Englund · 2026 · American Journal of Physiology-Cell Physiology
66. The dilemma of nuclear mechanical forces in DNA damage and repair
    Iqra Ali, Fangning Xu, Peng Qin, Juhui Qiu · 2025 · Biochemical and Biophysical Research Communications
67. WWP2-induced inhibition of hepatocellular carcinoma cellular senescence via the ubiquitination and degradation of p21
    Xiaojing Chen, Jihong Wang, Zihan Yan, Xinrui Du, Zhiyao Zhang, Xin Liu, Lanxin Hu, Kun He, Jing Zhang, Yunwei Han · 2025 · Cell Death and Disease
68. Senolytic-loaded asymmetric wound dressing for targeted senescent cell clearance in diabetic wound healing
    Ming Zhang, Yamei Wang, Yao Dai, Yan Hu, Wanting Fu, Yuhao Zhao, Hui Ma, Di Zhang, Ying Chen, Yixuan Zhou et al. · 2025 · Materials Today Bio
69. Isolation and Characterization of Endothelial-Colony Forming Cells (ECFC): Studying Endothelial Senescence for Translational Studies and for Personalized Medicine
    Koralia E. Paschalaki, Charis Pericleous · 2025 · Methods in molecular biology
70. SRSF3 knockdown-induced cellular senescence as a possible therapeutic strategy for non-small cell lung cancer
    Shinji Nakamichi, Natalia von Muhlinen, Leo Yamada, Jilian R. Melamed, Tyler Ellis Papp, Hamideh Parhiz, Drew Weissman, Izumi Horikawa, Curtis C. Harris · 2025 · Carcinogenesis
71. Induction of Senescence During Postpartum Mammary Gland Involution supports tissue remodeling and promotes postpartum tumorigenesis
    2024
72. Senotypes define the diverse landscape of senescent cells
    Marissa J. Schafer, Nathan Basisty, Ann Vogel Hertzel, Alexandra N. Rindone, Jennifer H. Elisseeff, Vidyani Suryadevara, Constantin Aliferis, Paul D. Robbins, Laura J. Niedernhofer, Karl N. Miller et al. · 2026 · Nature Aging
73. A spatial multi-omics atlas of immunosenescence reveals germinal-center B cell alteration in human lymph nodes
    Negin Farzad, Archibald Enninful, Yao Lu, Fabio Parisi, Anthony A. Fung, Yumi Kwon, Yajuan Li, Margaux Labrosse, Mingyu Yang, Francesco Strino et al. · 2026 · Cell Press Blue
74. Senescent cancer-associated fibroblasts in cancer progression: From formation to therapeutic opportunities
    Y R Feng, Xiaochen Zhi, Ting Xiao, Lin Feng · 2026 · Mechanisms of Ageing and Development
75. Risk Factors for Secondary Immunodeficiency in the Aged
    Anna Lang, Alexandros P. Grammatikos, Mark C. Ballow, Iris M. Otani, Sara Barmettler · 2026 · The Journal of Allergy and Clinical Immunology In Practice
76. SAMP-Score: a morphology-based machine learning classification method for screening pro-senescence compounds in p16 positive cancer cells
    Ryan Wallis, Bethany K. Hughes, Madeleine Moore, Emily A. O’Sullivan, Luke C. McIlvenna, Luke Gammon, Anthony G. Hope, Fiona Bellany, Parul Dixit, Claire J. Mackenzie et al. · 2025 · Aging
77. The protein phosphatase 6 subunit SAPS3 modulates lifespan by regulating metabolism
    Ying Yang, Da Eun Kang, Qi Fan, Eric Allan Hanse, Hosung Bae, Rocio A. Barahona, Xiyu Shen, Bryan I. Ruiz, Saiho Lee, Katherine R. Pasterczyk et al. · 2025 · Science Advances
78. The Senolytic Drug Navitoclax Protects the Brain After Experimental Ischemic Stroke
    Dianoush Falahatgaroshibi, Júlia Baixauli-Martín, Marı́a C. Burguete, Mikahela A. López‐Morales, Alicia Aliena‐Valero, José‐Esteban Peris, Juan B. Salom · 2026 · Pharmaceuticals
79. Modification of the dermal matrix by senescence associated lipids and its functional consequence
    Sarah Jelleschitz, Christopher Kremslehner, Ionela‐Mariana Nagelreiter, Michael Mildner, Melanie Salek, Christina Bauer, Alexandra Stiegler, Adrian Sandgren Fors, Michaela Schirato, Christian Freystätter et al. · 2026 · Redox Biology
80. Senescence caused by telomerase inactivation in myeloid, mesenchymal, and endothelial cells has distinct effects on cancer progression
    Joseph E. Rupert, Zhan‐Guo Gao, Yongmei Yu, Mikhail G. Kolonin · 2025 · Aging
81. Polystyrene nanoplastics promotes inflammation and aging in young mice through the oral-gut microbiome axis
    Ying Wang, Chunli Dong, Yi Xiao · 2026 · Frontiers in Immunology
82. Psoriasis-like disease prevents squamous skin tumor development by neutrophil-driven inflammation
    Panagiota Tsokkou, Martin Holcmann, Katharina Rindler, Kamil Mieczkowski, Lisa Ellen Shaw, Matthias Farlik, Maria Chiara Sibilia, Erwin Friedrich Wagner · 2026 · Proceedings of the National Academy of Sciences
83. Liver senescence in focus: Heterogeneity across aging and cancer
    Cleo L. Bishop · 2026 · Cell Genomics
84. Proteomic Dynamics Reveal Cell-Cycle and Rho GTPase Remodeling Associated with Transient Senescence Traits in Human Chondrocytes During Sustained IL-1β Signaling
    Hellen Paula Valerio, Thatiana Corrêa de Melo, Mariana Barbosa de Souza Rizzo, Amanda Teixeira de Melo, Miryam Paola Alvarez Flores, Ana Marisa Chudzinski‐Tavassi · 2026 · Cells
85. seneR: An R package for comprehensive senescence assessment and its application in type 2 diabetes and osteoarthritis
    Yi Zhang, Xinming Zhang, Cheng Chen, Bing Li, Yao LU, Xin Ma, Yunfeng Yang · 2025 · Computational and Structural Biotechnology Journal
86. Correlation Between the Proportion of Senescence-Associated β-Galactosidase-Stained CD8+ T Cells and Age: A Cross-Sectional Study in Japan
    Masaya Tsubokawa, Yoshiki Shimizu, Misato Yazaki, Shieri Shimodan, Masayuki Noguchi, Arisa Yamazaki, Tomomichi Watanabe, Makoto Ocho, Tsuyoshi Sakurada, Yoshie Hirose et al. · 2025 · International Journal of Molecular Sciences
87. Cell-Surface LAMP1 is a Senescence Marker in Aging and Idiopathic Pulmonary Fibrosis
    2025
88. Rejuvenating the aging gut by targeting senescence
    Marina Kolesnichenko · 2026 · Nature Aging
89. Integrative Omics Reveal Female‐Specific Benefits of p16 + Cell Clearance in Aging Mice
    Yao Lin, Boshi Wang, Mengling Huang, Justina Clarinda Wolters, Marco Demaria · 2025 · Advanced Science
90. A novel platform for precise senolysis
    Anastasia Conti, Raffaella Di Micco · 2025 · Mechanisms of Ageing and Development
91. Natural senolytic activity of Rhodiola rosea extract alleviates age-associated phenotypes via paraptosis
    Ryo Furuuchi, Yohko Yoshida, Goro Katsuumi, Takaaki Furihata, Yusuke Joki, Chieh Lun Hsiao, Masayoshi Suda, Hana Saito, Tamano Kumazaki, Hidefumi Makabe et al. · 2026 · iScience
92. Biological markers of aging across the menopause transition: current evidence
    Regina Castaneda, Erin R Uddenberg, Maria D. Hurtado Andrade, Jesse L. Meek, Kaylin N. Frankhouser, Stephanie S. Faubion, Eduardo N. Chini, Nathan K. LeBrasseur, Pamila Brar, CHRISANDRA L. SHUFELT · 2026 · Menopause The Journal of The North American Menopause Society
93. Topical Application of miR-200b-3p by Poloxamer 407-Based Hydrogel Accelerates Diabetic Wound Healing
    Wan‐Yu Lo, Cian-Huei Sin, Huang-Joe Wang · 2025 · Diabetes Metabolic Syndrome and Obesity
94. Activity of Angelica sinensis extract for cutaneous applications: antioxidant, anti-senescent, and antimicrobial effects
    Isabella Giacomini, Veronica Cocetta, Giulia Morandin, Marco Pinzerato, Caterina Dieni, Carolina Frison, Marco Biagi, Paola Brun, Stefano Dall’Acqua, Monica Montopoli · 2026 · Frontiers in Pharmacology
95. Mesothelin-Associated Anti-Senescence Through P53 in Pancreatic Ductal Adenocarcinoma
    Dongliang Liu, Jianming Lü, Changyi Chen, Qizhi Cathy Yao · 2025 · Cancers
96. IRF4 Enhances Radiosensitivity of Cervical Cancer by Inhibiting the PI3K/Akt/mTOR Pathway to Regulate Autophagy
    Meihui Gao, Zhaolei Cui, Huachun Song, Yanhong Li, A. Li, Jianfeng Zheng, Linying Liu, Xuefen Lin, Wankai Fu, Yang Sun · 2026 · Cancer Science
97. Spatial Profiling Identified Senescent Cancer-Associated Fibroblasts Localized in the Border Region of Human Pancreatic Ductal Adenocarcinoma
    Yoshiyuki Harada, Atsuhiro Masuda, Takanori Matsuura, Kenji Nagata, Yoshihide Nanno, Atsushi Masamune, Yuzo Kodama, Eiji Hara, Tomonori Matsumoto · 2026 · Cellular and Molecular Gastroenterology and Hepatology
98. Immune surveillance and immune evasion of senescent cells
    Pau Garcia-Baucells, Manuel Serrano, Corina Amor · 2026 · Nature reviews. Immunology
99. Roles of plasminogen activator inhibitor-1 in aging-related muscle and bone loss in mice
    Takashi Ohira, Naoyuki Kawao, Yuya Mizukami, Kiyotaka Okada, Akihito Nishikawa, Hisatoshi Yamao, Ayaka Yamada, Hiroshi Kaji · 2025 · Aging
100. Remodeling the sarcoma microenvironment by simultaneous targeting of urokinase-type plasminogen activator receptors and epidermal growth factor receptors to promote antitumor activity
     Ashley J. Schulte, Mitzi Lewellen, Wilaiwan Wisessmith Durose, Erin E. Nolan, Leyla A. Taghizadeh, Deborah Todhunter, Courtney Bush, Haeree Park Lang, Mary E. Brown, Taylor A. DePauw et al. · 2025 · Journal of Pharmacology and Experimental Therapeutics