The DOI matches its Crossref record; 297 of the 297 references it cites were found in a registry or an index.
Diabetes mellitus—Progress and opportunities in the evolving epidemic
Open accessAbstract
Diabetes, a complex multisystem metabolic disorder characterized by hyperglycemia, leads to complications that reduce quality of life and increase mortality. Diabetes pathophysiology includes dysfunction of beta cells, adipose tissue, skeletal muscle and liver. Type 1 diabetes (T1D) results from immune-mediated beta cell destruction. The more prevalent Type 2 diabetes (T2D) is a heterogenous disorder characterized by varying degrees of beta cell dysfunction in concert with insulin resistance. The strong association between obesity and type 2 diabetes involves pathways regulated by the central nervous system governing food intake and energy expenditure, integrating inputs from peripheral organs and the environment. The risk of developing diabetes or its complications represents interactions between genetic susceptibility and environmental factors including availability of nutritious food and other social determinants of health. This perspective reviews recent advances in understanding the pathophysiology and treatment of diabetes and its complications, that could alter the course of this prevalent disorder.
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Cites
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Cited by
Diabetes and its complications: molecular mechanisms, prevention and treatment
Zhao, L., Yuan, J., Yang, Q., Ma, J., Yang, F., Zou, Y., Liu, K., & Liu, F. (2026) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-025-02401-w · Cited by 80
Metadata
- Authors
- Abel, E. D., Gloyn, A. L., Evans-Molina, C., Joseph, J. J., Misra, S., Pajvani, U. B., Simcox, J., Susztak, K., & Drucker, D. J.
- Venue
- Cell
- Publisher
- Elsevier BV
- Published
- 2024-07
- Volume
- 187
- Issue
- 15
- Pages
- 3789-3820
- ISSN
- 0092-8674 (ISSN-L)
- OpenAlex
- W4400978809
- Cited by
- 292
- References
- 297
- FWCI
- 79.35
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Abel, E. D., Gloyn, A. L., Evans-Molina, C., Joseph, J. J., Misra, S., Pajvani, U. B., Simcox, J., Susztak, K., & Drucker, D. J. (2024). Diabetes mellitus—Progress and opportunities in the evolving epidemic. Cell. https://doi.org/10.1016/j.cell.2024.06.029
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
