Microglia dictate the impact of saturated fat consumption on hypothalamic inflammation and neuronal function.

Valdearcos, Martin, Robblee, Megan M., Benjamin, Daniel I., Nomura, Daniel K., Xu, Allison W., Koliwad, Suneil K.·2014·Cell Reports
DOI 10.1016/j.celrep.2014.11.018

Cited by (631)

Items 101–200 of 631

  1. Colony-stimulating factor 1 receptor blockade prevents fractionated whole-brain irradiation-induced memory deficits
    Xi Feng, Timothy D. Jopson, Maria Serena Paladini, Sharon Liu, Brian L. West, Nalin M. Gupta, Susanna Rosi · 2016 · Journal of Neuroinflammation
  2. Epigenetics and neurodegeneration: role of early-life nutrition
    Rosita Gabbianelli, Elisabetta Damiani · 2018 · The Journal of Nutritional Biochemistry
  3. Fatty food, fatty acids, and microglial priming in the adult and aged hippocampus and amygdala
    Michael J. Butler, Rachel M. Cole, Nicholas P. Deems, Martha Ann Belury, Ruth M. Barrientos · 2020 · Brain Behavior and Immunity
  4. Regulation of neuropeptide Y in body microenvironments and its potential application in therapies: a review
    Yan Zhang, Chu-Yun Liu, Wei-can Chen, Yan‐Chuan Shi, Congmei Wang, Shu Lin, He‐fan He · 2021 · Cell & Bioscience
  5. Nucleus accumbens cytoarchitecture predicts weight gain in children
    Rapuano, Kristina M., Laurent, Jennifer S., Hagler, Donald J., Hatton, Sean N., Thompson, Wesley K., Jernigan, Terry L., Dale, Anders M., Casey, B. J., Watts, Richard · 2020 · Proceedings of the National Academy of Sciences
  6. Fatty-acid-mediated hypothalamic inflammation and epigenetic programming
    Helena César, Luciana Pellegrini Pisani · 2016 · The Journal of Nutritional Biochemistry
  7. Hypothalamic inflammation in metabolic disorders and aging
    Anup Bhusal, Md Habibur Rahman, Kyoungho Suk · 2021 · Cellular and Molecular Life Sciences
  8. Epigenetic Regulation of Adipogenesis in Development of Metabolic Syndrome
    Richa Pant, Priyanka Firmal, Vibhuti Kumar Shah, Aftab Alam, Samit Chattopadhyay · 2021 · Frontiers in Cell and Developmental Biology
  9. Diabesity and mood disorders: Multiple links through the microbiota-gut-brain axis
    Aitak Farzi, Ahmed Mostafa Hassan, Geraldine Zenz, Peter D. Holzer · 2018 · Molecular Aspects of Medicine
  10. Reversal of High Fat Diet-Induced Obesity, Systemic Inflammation, and Astrogliosis by the NLRP3 Inflammasome Inhibitors NT-0249 and NT-0796
    Peter Thornton, Valérie Reader, Zsofia Digby, Pamela J. Smolak, Nicola A. Lindsay, David Harrison, Nick Clarke, Alan P. Watt · 2024 · Journal of Pharmacology and Experimental Therapeutics
  11. Glial cells as integrators of peripheral and central signals in the regulation of energy homeostasis
    Sreekala S. Nampoothiri, Rubén Nogueiras, Markus Schwaninger, Vincent Prévot · 2022 · Nature Metabolism
  12. The gut microbiome in anorexia nervosa: relevance for nutritional rehabilitation
    Ruusunen, Anu, Rocks, Tetyana, Jacka, Felice, Loughman, Amy · 2019 · Psychopharmacology
  13. Role of orexin A signaling in dietary palmitic acid-activated microglial cells
    Cayla M. Duffy, Ce Yuan, Lauren E. Wisdorf, Charles John Billington, Catherine M. Kotz, Joshua P. Nixon, Tammy A. Butterick · 2015 · Neuroscience Letters
  14. Quercetin Protects Obesity-Induced Hypothalamic Inflammation by Reducing Microglia-Mediated Inflammatory Responses via HO-1 Induction
    Jihyeon Yang, Chu-Sook Kim, Thai Hien Tu, Min‐Seon Kim, Tsuyoshi Goto, Teruo Kawada, Myung‐Sook Choi, Taesun Park, Mi‐Kyung Sung, Jong Won Yun et al. · 2017 · Nutrients
  15. The Significance of Hypothalamic Inflammation and Gliosis for the Pathogenesis of Obesity in Humans
    LETICIA ESPOSITO SEWAYBRICKER, Alyssa Huang, Suchitra Chandrasekaran, Susan J. Melhorn, Ellen A. Schur · 2022 · Endocrine Reviews
  16. Recent Updates on Obesity Treatments: Available Drugs and Future Directions
    Nathalia Romanelli Vicente Dragano, Johan Fernø, Carlos Diéguez, Miguel López, Edward Milbank · 2020 · Neuroscience
  17. Ketosis may promote brain macroautophagy by activating Sirt1 and hypoxia-inducible factor-1
    Mark Frederick McCarty, James J. DiNicolantonio, James Henry O’Keefe · 2015 · Medical Hypotheses
  18. Dietary fat exacerbates postprandial hypothalamic inflammation involving glial fibrillary acidic protein‐positive cells and microglia in male mice
    Céline Cansell, Katharina Stobbe, Clara Sanchez, Ophélia Le Thuc, Coralie‐Anne Mosser, Selma Ben Fradj, Joris Leredde, Cynthia Lebeaupin, Delphine Debayle, Lucile Fleuriot et al. · 2020 · Glia
  19. Specific gut microbial, biological, and psychiatric profiling related to binge eating disorders: A cross-sectional study in obese patients
    Quentin Leyrolle, Renáta Cserjési, Maria D.G.H. Mulders, Giorgia Zamariola, Sophie Hiel, Marco A. Gianfrancesco, Julie Rodriguez, Daphnée Portheault, Camille Amadieu, Sophie Leclercq et al. · 2020 · Clinical Nutrition
  20. Pathogenesis of Dementia
    Janusz Wiesław Błaszczyk · 2022 · International Journal of Molecular Sciences
  21. Glial cells and energy balance.
    P. Argente-Arizón, S. Guerra-Cantera, L. Garcia-Segura, J. Argente, J. Chowen · 2017 · Journal of Molecular Endocrinology
  22. Transcriptomic characterization of microglia activation in a rat model of ischemic stroke
    Wenjun Deng, Emiri T. Mandeville, Yasukazu Terasaki, Wenlu Li, Julie C. Holder, Aaron TT Chuang, MingMing Ning, Ken Arai, Eng H. Lo, Changhong Xing · 2020 · Journal of Cerebral Blood Flow & Metabolism
  23. Microglia Regulate Neuronal Circuits in Homeostatic and High-Fat Diet-Induced Inflammatory Conditions
    Xiaolan Wang, Lianjian Li · 2021 · Frontiers in Cellular Neuroscience
  24. Astrocytic pyruvate dehydrogenase kinase-2 is involved in hypothalamic inflammation in mouse models of diabetes
    Md Habibur Rahman, Anup Bhusal, Jae‐Hong Kim, Mithilesh Kumar Jha, Gyun Jee Song, Younghoon Go, Il‐Sung Jang, In‐Kyu Lee, Kyoungho Suk · 2020 · Nature Communications
  25. Age-Associated Weight Gain, Leptin, and SIRT1: A Possible Role for Hypothalamic SIRT1 in the Prevention of Weight Gain and Aging through Modulation of Leptin Sensitivity
    Tsutomu Sasaki · 2015 · Frontiers in Endocrinology
  26. Targeted Gene Editing of Glia Maturation Factor in Microglia: a Novel Alzheimer’s Disease Therapeutic Target
    Sudhanshu P. Raikwar, Ramasamy Thangavel, Iuliia Dubova, Govindhasamy Pushpavathi Selvakumar, Mohammad Ejaz Ahmed, Duraisamy Kempuraj, Smita A. Zaheer, Shankar S. Iyer, Asgar Zaheer · 2018 · Molecular Neurobiology
  27. Linking atypical depression and insulin resistance-related disorders via low-grade chronic inflammation: Integrating the phenotypic, molecular and neuroanatomical dimensions
    Sen, Zümrüt Duygu, Danyeli, Lena Vera, Woelfer, Marie, Lamers, Femke, Wagner, Gerd, Sobanski, Thomas, Walter, Martin · 2021 · Brain, Behavior, and Immunity
  28. Macrophages Promote Repair of Inner Hair Cell Ribbon Synapses following Noise-Induced Cochlear Synaptopathy
    Vijayprakash Manickam, Dinesh Yugraj Gawande, Andrew R. Stothert, Anna C. Clayman, Lyudmila Batalkina, Mark E. Warchol, Kevin K. Ohlemiller, Tejbeer Kaur · 2023 · Journal of Neuroscience
  29. Deficiency of PTP1B Attenuates Hypothalamic Inflammation via Activation of the JAK2-STAT3 Pathway in Microglia
    Taku Tsunekawa, Ryoichi Banno, Akira Mizoguchi, Mariko Sugiyama, Takashi Tominaga, Takeshi Onoue, Daisuke Hagiwara, Yoshihiro Ito, Shintaro Iwama, Motomitsu Goto et al. · 2017 · EBioMedicine
  30. Neuroinflammatory and autonomic mechanisms in diabetes and hypertension
    Cheng Han, Matthew W. Rice, Dongsheng Cai · 2016 · American Journal of Physiology-Endocrinology and Metabolism
  31. Identification of a fatty acid binding protein4-UCP2 axis regulating microglial mediated neuroinflammation
    Cayla M. Duffy, Hongliang Xu, Joshua P. Nixon, David Bernlohr, Tammy A. Butterick · 2017 · Molecular and Cellular Neuroscience
  32. Palmitic Acid Reduces the Autophagic Flux and Insulin Sensitivity Through the Activation of the Free Fatty Acid Receptor 1 (FFAR1) in the Hypothalamic Neuronal Cell Line N43/5
    María Paz Hernández‐Cáceres, Lilian Toledo, Francisco Díaz‐Castro, Yenniffer Ávalos, Paulina Burgos, Carla Narro, Daniel Peña‐Oyarzún, Jasson Espinoza-Caicedo, Flavia Cifuentes-Araneda, Fernanda Navarro-Aguad et al. · 2019 · Frontiers in Endocrinology
  33. Physiology of Microglia
    Tuan Leng Tay, Micaël Carrier, Marie‐Ève Tremblay · 2019 · Advances in experimental medicine and biology
  34. Conditional microglial depletion in rats leads to reversible anorexia and weight loss by disrupting gustatory circuitry
    Simone N. De Luca, Luba Sominsky, Alita Soch, Hao Wang, Ilvana Ziko, Michelle M. Rank, Sarah J. Spencer · 2018 · Brain Behavior and Immunity
  35. Trained Immunity: Linking Obesity and Cardiovascular Disease across the Life-Course?
    Siroon Bekkering, Christoph C.S. Saner, Niels Peter Riksen, Mihai G. Netea, Matthew A. Sabin, Richard Saffery, Rinke Stienstra, David Paul Burgner · 2020 · Trends in Endocrinology and Metabolism
  36. CerS6-dependent ceramide synthesis in hypothalamic neurons promotes ER/mitochondrial stress and impairs glucose homeostasis in obese mice
    Philipp Hammerschmidt, Sophie Marie Steculorum, Cécile L. Bandet, Almudena Del Río-Martín, Lukas Steuernagel, Vivien Kohlhaas, Marvin Feldmann, Luis Varela, Adam Majcher, Marta Quatorze Correia et al. · 2023 · Nature Communications
  37. Palmitic acid triggers inflammatory responses in N42 cultured hypothalamic cells partially via ceramide synthesis but not via TLR4
    Domenico Sergi, Amanda C. Morris, DARCY E. KAHN, Fiona Hamilton McLean, Elizabeth A. Hay, Phil Kubitz, Alasdair MacKenzie, Maria‐Grazia Martinoli, Janice E. Drew, Lynda M. Williams · 2018 · Nutritional Neuroscience
  38. Distinct metabolic patterns during microglial remodeling by oleate and palmitate
    Chausse, Bruno, Kakimoto, Pamela A., Caldeira-da-Silva, Camille C., Chaves-Filho, Adriano B., Yoshinaga, Marcos Y., da Silva, Railmara Pereira, Miyamoto, Sayuri, Kowaltowski, Alicia J. · 2019 · Bioscience Reports
  39. Impaired fear extinction retention and increased anxiety-like behaviours induced by limited daily access to a high-fat/high-sugar diet in male rats: Implications for diet-induced prefrontal cortex dysregulation
    Kathryn Baker, Amy Claire Reichelt · 2016 · Neurobiology of Learning and Memory
  40. Cellular Contributors to Hypothalamic Inflammation in Obesity.
    Chan Hee Lee, Kyoungho Suk, Rina Yu, Min‐Seon Kim · 2020 · PubMed Central
  41. Fatty Acid Synthesis in Glial Cells of the CNS
    Aida V. Garcia Corrales, Mansour Haidar, Jeroen F. J. Bogie, Jerome J. A. Hendriks · 2021 · International Journal of Molecular Sciences
  42. Mechanistic insight into high-fat diet-induced metabolic inflammation in the arcuate nucleus of the hypothalamus
    Rahim Ullah, Naveed Rauf, Ghulam Nabi, Yi Shen, Zhou Yu-Dong, Junfen Fu · 2021 · Biomedicine & Pharmacotherapy
  43. Hypothalamic inflammation and malfunctioning glia in the pathophysiology of obesity and diabetes: Translational significance
    Md Habibur Rahman, Anup Bhusal, Won‐Ha Lee, In‐Kyu Lee, Kyoungho Suk · 2018 · Biochemical Pharmacology
  44. Visceral Adipose Tissue Accumulation and Residual Cardiovascular Risk
    Thierry H. Le Jemtel, Rohan Samson, Gregory Paul Milligan, Abhishek Jaiswal, Suzanne Oparil · 2018 · Current Hypertension Reports
  45. Deep Brain Stimulation for Obesity: A Review and Future Directions
    Douglas Affonso Formolo, Joana Margarida Gaspar, Hiago Murilo Melo, Tuany Eichwald, Ramiro Javier Zepeda, Alexandra Latini, Michael S. Okun, Roger Walz · 2019 · Frontiers in Neuroscience
  46. Regulation of microglia population dynamics throughout development, health, and disease
    Brady P. Hammond, Rupali Manek, Bradley J. Kerr, Matthew Scott Macauley, Jason R. Plemel · 2021 · Glia
  47. The Role of the Human Hypothalamus in Food Intake Networks: An MRI Perspective
    Coleen Roger, Adèle Lasbleiz, Maxime Guye, Anne Dutour, Bénédicte Gaborit, Jean‐Philippe Ranjeva · 2022 · Frontiers in Nutrition
  48. Links between Childhood Obesity, High-Fat Diet, and Central Precocious Puberty
    Valeria Calcaterra, Vittoria Carlotta Magenes, Chiara Hruby, Francesca Siccardo, Alessandra Mari, Erika Cordaro, Valentina Fabiano, Gianvincenzo Zuccotti · 2023 · Children
  49. Dietary Fat Modulation of Gut Microbiota and Impact on Regulatory Pathways Controlling Food Intake
    Sevag Hamamah, Arman Amin, Abdul Latif Al-Kassir, Judith Chuang, Mihai Covașă · 2023 · Nutrients
  50. Low-Fat Diet With Caloric Restriction Reduces White Matter Microglia Activation During Aging
    Zhuoran Yin, Divya D. A. Raj, Wandert Schaafsma, Roel A. van der Heijden, Susanne M. Kooistra, Aaffien C. Reijne, Xiaoming Zhang, Jill Moser, Nieske Brouwer, Peter Heeringa et al. · 2018 · Frontiers in Molecular Neuroscience
  51. Mechanisms of inflammation after ischemic stroke in brain-peripheral crosstalk
    Ling Xie, Ming He, Caidi Ying, Haifeng Chu · 2024 · Frontiers in Molecular Neuroscience
  52. Diet-induced cellular neuroinflammation in the hypothalamus: Mechanistic insights from investigation of neurons and microglia
    Dean Q. Tran, Erika K. Tse, Mun Heui Kim, Denise D. Belsham · 2016 · Molecular and Cellular Endocrinology
  53. Sex differences in the neuroendocrine control of metabolism and the implication of astrocytes
    Julie Ann Chowen, Pilar Argente-Arizón, Alejandra Freire‐Regatillo, Jesús Argente · 2017 · Frontiers in Neuroendocrinology
  54. Neural Underpinnings of Obesity: The Role of Oxidative Stress and Inflammation in the Brain
    Caitlyn A. Mullins, Ritchel B. Gannaban, Md Shahjalal Hossain Khan, Harsh Shah, Md. Abu Bakkar Siddik, Vijay K. Hegde, P. Hemachandra Reddy, Andrew Changhun Shin · 2020 · Antioxidants
  55. High-fat diet and neuroinflammation: The role of mitochondria
    Mingxue Song, Yao Bai, Fuyong Song · 2025 · Pharmacological Research
  56. Cell and molecular mechanisms behind diet‐induced hypothalamic inflammation and obesity
    Yenniffer Ávalos, Bredford Kerr, Manuel Alejandro Maliqueo, Mauricio D. Dorfman · 2018 · Journal of Neuroendocrinology
  57. Palmitic acid promotes resistin-induced insulin resistance and inflammation in SH-SY5Y human neuroblastoma
    Hamza Amine, Yacir Benomar, Mohammed Taouis · 2021 · Scientific Reports
  58. Diet-Induced Obesity Disturbs Microglial Immunometabolism in a Time-of-Day Manner
    Milanova, Irina V., Kalsbeek, Martin J. T., Wang, Xiao-Lan, Korpel, Nikita L., Stenvers, Dirk Jan, Wolff, Samantha E. C., de Goede, Paul, Heijboer, Annemieke C., Fliers, Eric, la Fleur, Susanne E. et al. · 2019 · Frontiers in Endocrinology
  59. Hypothalamic microglia as potential regulators of metabolic physiology.
    Valdearcos, Martin, Myers, Martin G., Koliwad, Suneil K. · 2019 · Nature Metabolism
  60. Leptin in normal physiology and leptin resistance
    Shufen Li, Xi Li · 2015 · 中国科学通报：英文版
  61. Maternal n-3 polyunsaturated fatty acid dietary supply modulates microglia lipid content in the offspring
    Charlotte Rey, Agnès Nadjar, Florent Joffre, Camille Amadieu, Agnès Aubert, Carole Vaysse, Véronique Pallet, Sophie Layé, Corinne Joffre · 2018 · Prostaglandins Leukotrienes and Essential Fatty Acids
  62. Nutrient Sensing by Hypothalamic Tanycytes
    Roberto Javier Elizondo-Vega, Antonia Recabal, Karina Oyarce · 2019 · Frontiers in Endocrinology
  63. Interleukin-6 Expression by Hypothalamic Microglia in Multiple Inflammatory Contexts: A Systematic Review
    Vanessa Cristina Dias Bóbbo, Carlos Poblete Jara, Natália Ferreira Mendes, Joseane Morari, Licio Augusto Velloso, ELIANA PEREIRA DE ARAUJO · 2019 · BioMed Research International
  64. Direct and indirect effects of lipids on microglia function
    Leyrolle, Q., Layé, S., Nadjar, A. · 2019 · Neuroscience Letters
  65. Phlorofucofuroeckol B suppresses inflammatory responses by down-regulating nuclear factor κB activation via Akt, ERK, and JNK in LPS-stimulated microglial cells
    Dong-Kyung Yu, Bonggi Lee, Misung Kwon, Na‐Young Yoon, Taisun Shin, Nam-Gil Kim, Jae‐Sue Choi, Hyeung‐Rak Kim · 2015 · International Immunopharmacology
  66. Antioxidant bilirubin works in multiple ways to reduce risk for obesity and its health complications
    James J. DiNicolantonio, Mark Frederick McCarty, James Henry O’Keefe · 2018 · Open Heart
  67. Long-term bisphenol A exposure exacerbates diet-induced prediabetes via TLR4-dependent hypothalamic inflammation
    Qinlong Ma, Ping Deng, Min Lin, Lingling Yang, Le Li, Lu Guo, Lei Zhang, Mindi He, Yonghui Lu, Huifeng Pi et al. · 2020 · Journal of Hazardous Materials
  68. Obesity-associated microglial inflammatory activation paradoxically improves glucose tolerance
    John D. Douglass, Kelly M. Ness, Martín Valdearcos, Alice C. Wyse‐Jackson, Mauricio D. Dorfman, Jeremy M. Frey, Rachael D. Fasnacht, Olivia D. Santiago, Anzela Niraula, Jineta Banerjee et al. · 2023 · Cell Metabolism
  69. Role of metabolic programming in the modulation of microglia phagocytosis by lipids
    Nadjar, A. · 2018 · Prostaglandins, Leukotrienes and Essential Fatty Acids
  70. Loss of IRF2BP2 in Microglia Increases Inflammation and Functional Deficits after Focal Ischemic Brain Injury
    Shelly Abad Cruz, Aswin Hari, Zhaohong Qin, Pascal Couture, Hua Huang, Diane C. Lagace, Alexandre F.R. Stewart, Hsiao‐Huei Chen · 2017 · Frontiers in Cellular Neuroscience
  71. LPS-induced lipid alterations in microglia revealed by MALDI mass spectrometry-based cell fingerprinting in neuroinflammation studies
    Martina Blank, Thomas Enzlein, Carsten Hopf · 2022 · Scientific Reports
  72. Bioactive lipids as new class of microglial modulators: When nutrition meets neuroimunology
    Agnès Nadjar, Quentin Leyrolle, Corinne Joffre, Sophie Layé · 2016 · Progress in Neuro-Psychopharmacology and Biological Psychiatry
  73. Distinct Transcriptional Responses across Tissue-Resident Macrophages to Short-Term and Long-Term Metabolic Challenge
    Urszula Brykczynska, Marco Geigges, Sophia J. Wiedemann, Erez Dror, Marianne Böni‐Schnetzler, Christoph Hess, Marc Yves Donath, Renato Paro · 2020 · Cell Reports
  74. Is human obesity an inflammatory disease of the hypothalamus?
    Lena Sonnefeld, Nathalie Rohmann, Corinna Geisler, Matthias Laudes · 2023 · European Journal of Endocrinology
  75. Total Western Diet Alters Mechanical and Thermal Sensitivity and Prolongs Hypersensitivity Following Complete Freund's Adjuvant in Mice
    Stacie K. Totsch, Megan E. Waite, Ashleigh M. Tomkovich, Tammie L. Quinn, Barbara Ann Gower, Robert E. Sorge · 2015 · Journal of Pain
  76. Potential relationship between dietary long-chain saturated fatty acids and hypothalamic dysfunction in obesity
    Domenico Sergi, Lynda M. Williams · 2019 · Nutrition Reviews
  77. The interrelationship of body mass index with gray matter volume and resting-state functional connectivity of the hypothalamus
    Thang M. Le, Ding‐Lieh Liao, Jaime S. Ide, Sheng Zhang, Simon Zhornitsky, Wuyi Wang, Chiang-Shan Ray Li · 2019 · International Journal of Obesity
  78. Impaired brain homeostasis and neurogenesis in diet-induced overweight zebrafish: a preventive role from A. borbonica extract
    Batoul Ghaddar, Bryan Veeren, Philippe Rondeau, Matthieu Bringart, Christian Lefebvre d’Hellencourt, Olivier Meilhac, Jean‐Loup Bascands, Nicolas Diotel · 2020 · Scientific Reports
  79. Lifestyle-dependent microglial plasticity: training the brain guardians
    Marcus Augusto‐Oliveira, Alexei Verkhratsky · 2021 · Biology Direct
  80. The impact of the Standard American Diet in rats: Effects on behavior, physiology and recovery from inflammatory injury
    Stacie K. Totsch, Tammie L. Quinn, Larissa J. Strath, Laura J. McMeekin, Rita Marie Cowell, Barbara Ann Gower, Robert E. Sorge · 2017 · Scandinavian Journal of Pain
  81. Function of astrocyte MyD88 in high-fat-diet-induced hypothalamic inflammation
    Sungho Jin, Kwang Kon Kim, Byong Seo Park, Dong Hee Kim, Bora Jeong, Dasol Kang, Tae Hwan Lee, Jeong Woo Park, Jae Geun Kim, Byung Ju Lee · 2020 · Journal of Neuroinflammation
  82. Non-Neuronal Cells in the Hypothalamic Adaptation to Metabolic Signals
    Alejandra Freire-Regatillo, P. Argente-Arizón, J. Argente, L. Garcia-Segura, J. Chowen · 2017 · Frontiers in Endocrinology
  83. Microglia, neurodegeneration and loss of neuroendocrine control
    Julie Ann Chowen, Luis Miguel García‐Segura · 2019 · Progress in Neurobiology
  84. Palmitic acid reduces the autophagic flux in hypothalamic neurons by impairing autophagosome-lysosome fusion and endolysosomal dynamics
    María Paz Hernández‐Cáceres, Karina Cereceda, Sergio Hernández, Ying Li, Carla Narro, Patricia Rivera, Patricio Silva, Yenniffer Ávalos, Claudia Jara, Paulina Burgos et al. · 2020 · Molecular & Cellular Oncology
  85. Microglial Lipid Biology in the Hypothalamic Regulation of Metabolic Homeostasis
    Andrew Folick, Suneil K. Koliwad, Martín Valdearcos · 2021 · Frontiers in Endocrinology
  86. Neuroimmunometabolism: A New Pathological Nexus Underlying Neurodegenerative Disorders
    Swarup Mitra, Avijit Banik, Sumit Saurabh, Malabika Maulik, Shailesh Khatri · 2022 · Journal of Neuroscience
  87. Trapped fat: Obesity pathogenesis as an intrinsic disorder in metabolic fuel partitioning
    Mark I. Friedman, Thorkild I. A. Sørensen, Gary Taubes, Jens Teglgaard Lund, David S. Ludwig · 2024 · Obesity Reviews
  88. The Hypothalamic Inflammatory/Gliosis Response to Neonatal Overnutrition Is Sex and Age Dependent
    Pilar Argente-Arizón, Francisca Díaz, Purificación Ros, Vicente Barrios, Manuel Tena‐Sempere, Luis Miguel García‐Segura, Jesús Argente, Julie Ann Chowen · 2017 · Endocrinology
  89. Microglia immunometabolism: From metabolic disorders to single cell metabolism
    Rosa Chiara Paolicelli, Stefano Angiari · 2019 · Seminars in Cell and Developmental Biology
  90. Childhood Obesity, Hypothalamic Inflammation, and the Onset of Puberty: A Narrative Review
    Anastasia-Maria Tzounakou, Galateia Stathori, George Paltoglou, Georgios Valsamakis, George P. Mastorakos, Nikolaos Vlahos, Evangelia Charmandari · 2024 · Nutrients
  91. TGF-β1 down-regulation in the mediobasal hypothalamus attenuates hypothalamic inflammation and protects against diet-induced obesity
    Natália Ferreira Mendes, Joana Margarida Gaspar, José Carlos de Lima Júnior, José Donato, Licio Augusto Velloso, ELIANA PEREIRA DE ARAUJO · 2018 · Metabolism
  92. Ferulic acid may target MyD88-mediated pro-inflammatory signaling – Implications for the health protection afforded by whole grains, anthocyanins, and coffee
    Mark Frederick McCarty, Simon Bernard Iloki Assanga · 2018 · Medical Hypotheses
  93. Metabolic Stress Alters Antioxidant Systems, Suppresses the Adiponectin Receptor 1 and Induces Alzheimer’s Like Pathology in Mice Brain
    Jong Ryeal Hahm, Myeung Hoon Jo, Rahat Ullah, Min Woo Kim, Myeong Ok Kim · 2020 · Cells
  94. Embryonic Microglia Interact with Hypothalamic Radial Glia during Development and Upregulate the TAM Receptors MERTK and AXL following an Insult
    Jessica M. Rosin, Candace M. Marsters, Faizan Malik, Rena Far, Lata Adnani, Carol Schuurmans, Quentin J. Pittman, Deborah Marie Kurrasch · 2021 · Cell Reports
  95. Limitations of PLX3397 as a microglial investigational tool: peripheral and off-target effects dictate the response to inflammation
    Wouter Claeys, Daan Verhaege, Griet Van Imschoot, Elien Van Wonterghem, Lore Van Acker, Laura Amelinck, Federico F. De Ponti, Charlotte L. Scott, Anja M. Geerts, Christophe Van Steenkiste et al. · 2023 · Frontiers in Immunology
  96. Kimchi intake alleviates obesity-induced neuroinflammation by modulating the gut-brain axis
    Namhee Kim, Ji-Eun Lee, Hye Seon Song, Young Joon Oh, Min‐Sung Kwon, Misun Yun, Seul Ki Lim, Hyo Kyeong Park, Young Seo Jang, Sulhee Lee et al. · 2022 · Food Research International
  97. Dietary fatty acid composition drives neuroinflammation and impaired behavior in obesity
    Clara Sanchez, Cecilia Colson, Nadine Gautier, Pascal Noser, Juliette Salvi, Maxime Villet, Lucile Fleuriot, Caroline Peltier, Pascal Schlich, Frédéric Brau et al. · 2024 · Brain Behavior and Immunity
  98. Microglial Depletion, a New Tool in Neuroinflammatory Disorders: Comparison of Pharmacological Inhibitors of the CSF ‐ 1R
    David Guenoun, Nathan Blaise, Alexandre Sellam, Julie Roupret‐Serzec, Alice Jacquens, Juliette Van Steenwinckel, Pierre Gressèns, Cindy Bokobza · 2024 · Glia
  99. Lipid and lipoprotein metabolism in microglia: Alzheimer’s disease mechanisms and interventions
    Kayla G. Sprenger, Emma E Lietzke, John Melchior, Kimberley D. Bruce · 2025 · Journal of Lipid Research
  100. Radiologic evidence that hypothalamic gliosis is improved after bariatric surgery in obese women with type 2 diabetes
    Simone van de Sande‐Lee, Susan J. Melhorn, Briana Rachid, SylkaO. Rodovalho, José Carlos de Lima Júnior, Brunno Machado de Campos, Tatiane Pedro, Guilherme C. Beltramini, Élinton Adami Chaim, José Carlos Pareja et al. · 2019 · International Journal of Obesity