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Central Role of ULK1 in Type I Interferon Signaling
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“Finally, there are several ULK1 substrates that exhibit no, or at least no apparent, function in autophagy, or that have additional cellular functions separate from autophagy.”
From Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1 (2021) · cites this paper as [727]
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“No significant differences in IFNdependent Isg15, Isg54, and Irf9 mRNA expression were observed between control cells and cells in which ATG5 was knocked down (Figures 4A–4D).”
BackgroundInfluentialIdentifying differentially expressed genes using false discovery rate controlling procedures
Reiner, A., Yekutieli, D., & Benjamini, Y. (2003) · Bioinformatics · doi:10.1093/bioinformatics/btf877 · Cited by 1,765
The requirement of uncoordinated 51-like kinase 1 (ULK1) and ULK2 in the regulation of autophagy
Lee, E.-J., & Tournier, C. (2011) · Autophagy · doi:10.4161/auto.7.7.15450 · Cited by 186 · cited 2×
“, 2011), as ULK1 and ULK2 kinases were previously shown to have at least partially redundant functions in fibroblasts (Kundu et al., 2008; Lee and Tournier, 2011).”
BackgroundMethod
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cGAS surveillance of micronuclei links genome instability to innate immunity
Mackenzie, K. J., Carroll, P., Martin, C.-A., Murina, O., Fluteau, A., Simpson, D. J., Olova, N., Sutcliffe, H., Rainger, J. K., Leitch, A., et al. (2017) · Nature · doi:10.1038/nature23449 · Cited by 1,752
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Kroczynska, B., Rafidi, R. L., Majchrzak-Kita, B., Kosciuczuk, E. M., Blyth, G. T., Jemielity, J., Warminska, Z., Saleiro, D., Mehrotra, S., Arslan, A. D., et al. (2016) · Journal of Biological Chemistry · doi:10.1074/jbc.m115.664995 · Cited by 29
Self-citation
Metadata
- Authors
- Saleiro, D., Mehrotra, S., Kroczynska, B., Beauchamp, E. M., Lisowski, P., Majchrzak-Kita, B., Bhagat, T. D., Stein, B. L., McMahon, B., Altman, J. K., Kosciuczuk, E. M., Baker, D. P., Jie, C., Jafari, N., Thompson, C. B., Levine, R. L., Fish, E. N., Verma, A. K., & Platanias, L. C.
- Venue
- Cell Reports
- Publisher
- Elsevier BV
- Published
- 2015-04
- Volume
- 11
- Issue
- 4
- Pages
- 605-617
- ISSN
- 2211-1247
- PMC
- PMC4477687
- Cited by
- 74
- References
- 3
- Language
- en
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- Saleiro, D., Mehrotra, S., Kroczynska, B., Beauchamp, E. M., Lisowski, P., Majchrzak-Kita, B., Bhagat, T. D., Stein, B. L., McMahon, B., Altman, J. K., Kosciuczuk, E. M., Baker, D. P., Jie, C., Jafari, N., Thompson, C. B., Levine, R. L., Fish, E. N., Verma, A. K., & Platanias, L. C. (2015). Central Role of ULK1 in Type I Interferon Signaling. Cell Reports. https://doi.org/10.1016/j.celrep.2015.03.056