The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Cyclic Dinucleotides Trigger ULK1 (ATG1) Phosphorylation of STING to Prevent Sustained Innate Immune Signaling
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Finally, there are several ULK1 substrates that exhibit no, or at least no apparent, function in autophagy, or that have additional cellular functions separate from autophagy.”
From Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1 (2021) · cites this paper as [721]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway
Sun, L., Wu, J., Du, F., Chen, X., & Chen, Z. J. (2013) · Science · doi:10.1126/science.1232458 · Cited by 4,996
STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
Ishikawa, H., & Barber, G. N. (2008) · Nature · doi:10.1038/nature07317 · Cited by 3,576
Self-citationSTING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity
Ishikawa, H., Ma, Z., & Barber, G. N. (2009) · Nature · doi:10.1038/nature08476 · Cited by 2,759
Self-citationSTING is a direct innate immune sensor of cyclic di-GMP
Burdette, D. L., Monroe, K. M., Sotelo-Troha, K., Iwig, J. S., Eckert, B., Hyodo, M., Hayakawa, Y., & Vance, R. E. (2011) · Nature · doi:10.1038/nature10429 · Cited by 1,570
Gao, P., Ascano, M., Wu, Y., Barchet, W., Gaffney, B. L., Zillinger, T., Serganov, A. A., Liu, Y., Jones, R. A., Hartmann, G., et al. (2013) · Cell · doi:10.1016/j.cell.2013.04.046 · Cited by 1,101
The role of the Atg1/ULK1 complex in autophagy regulation
Mizushima, N. (2010) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2009.12.004 · Cited by 1,062
Henault, J., Martinez, J., Riggs, J. M., Tian, J., Mehta, P., Clarke, L., Sasai, M., Latz, E., Brinkmann, M. M., Iwasaki, A., et al. (2012) · Immunity · doi:10.1016/j.immuni.2012.09.014 · Cited by 348
Flagged first, then by citations
Research works printed but not linked: 22
- Abe, 2013, STING recognition of cytoplasmic DNA instigates cellular defense, Mol. Cell, 50, 5, 10.1016/j.molcel.2013.01.039 · DOI
- Ablasser, 2013, cGAS produces a 2′-5′-linked cyclic dinucleotide second messenger that activates STING, Nature, 498, 380, 10.1038/nature12306 · DOI · Paper page
- Ahn, 2012, STING manifests self DNA-dependent inflammatory disease, Proc. Natl. Acad. Sci. USA, 109, 19386, 10.1073/pnas.1215006109 · DOI
- Alers, 2012, Role of AMPK-mTOR-Ulk1/2 in the regulation of autophagy: cross talk, shortcuts, and feedbacks, Mol. Cell. Biol., 32, 2, 10.1128/MCB.06159-11 · DOI · Paper page
- Alexander, 2011, The role of LKB1 and AMPK in cellular responses to stress and damage, FEBS Lett., 585, 952, 10.1016/j.febslet.2011.03.010 · DOI
- Blasius, 2010, Intracellular toll-like receptors, Immunity, 32, 305, 10.1016/j.immuni.2010.03.012 · DOI
- Civril, 2013, Structural mechanism of cytosolic DNA sensing by cGAS, Nature, 498, 332, 10.1038/nature12305 · DOI
- Diner, 2013, The innate immune DNA sensor cGAS produces a noncanonical cyclic dinucleotide that activates human STING, Cell Rep., 3, 1355, 10.1016/j.celrep.2013.05.009 · DOI · Paper page
- Fu, 2011, Bile acid stimulates hepatocyte polarization through a cAMP-Epac-MEK-LKB1-AMPK pathway, Proc. Natl. Acad. Sci. USA, 108, 1403, 10.1073/pnas.1018376108 · DOI
- Gall, 2012, Autoimmunity initiates in nonhematopoietic cells and progresses via lymphocytes in an interferon-dependent autoimmune disease, Immunity, 36, 120, 10.1016/j.immuni.2011.11.018 · DOI · Paper page
- Hardie, 2012, AMP-activated protein kinase: a target for drugs both ancient and modern, Chem. Biol., 19, 1222, 10.1016/j.chembiol.2012.08.019 · DOI
- Jin, 2008, MPYS, a novel membrane tetraspanner, is associated with major histocompatibility complex class II and mediates transduction of apoptotic signals, Mol. Cell. Biol., 28, 5014, 10.1128/MCB.00640-08 · DOI
- Kawai, 2011, Toll-like receptors and their crosstalk with other innate receptors in infection and immunity, Immunity, 34, 637, 10.1016/j.immuni.2011.05.006 · DOI · Paper page
- Kranzusch, 2013, Structure of human cGAS reveals a conserved family of second-messenger enzymes in innate immunity, Cell Rep., 3, 1362, 10.1016/j.celrep.2013.05.008 · DOI
- Saitoh, 2009, Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response, Proc. Natl. Acad. Sci. USA, 106, 20842, 10.1073/pnas.0911267106 · DOI · Paper page
- Sun, 2009, ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization, Proc. Natl. Acad. Sci. USA, 106, 8653, 10.1073/pnas.0900850106 · DOI
- Tamura, 2008, The IRF family transcription factors in immunity and oncogenesis, Annu. Rev. Immunol., 26, 535, 10.1146/annurev.immunol.26.021607.090400 · DOI · Paper page
- Tanaka, 2012, STING specifies IRF3 phosphorylation by TBK1 in the cytosolic DNA signaling pathway, Sci. Signal., 5, ra20, 10.1126/scisignal.2002521 · DOI
- Tooze, 2010, Trafficking and signaling in mammalian autophagy, IUBMB Life, 62, 503, 10.1002/iub.334 · DOI
- Woodward, 2010, c-di-AMP secreted by intracellular Listeria monocytogenes activates a host type I interferon response, Science, 328, 1703, 10.1126/science.1189801 · DOI
- Zhang, 2013, Cyclic GMP-AMP containing mixed phosphodiester linkages is an endogenous high-affinity ligand for STING, Mol. Cell, 51, 226, 10.1016/j.molcel.2013.05.022 · DOI
- Zhong, 2008, The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation, Immunity, 29, 538, 10.1016/j.immuni.2008.09.003 · DOI
Cited by
Sorted by citations
Biological Functions of Autophagy Genes: A Disease Perspective
Levine, B., & Kroemer, G. (2019) · Cell · doi:10.1016/j.cell.2018.09.048 · Cited by 2,832
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1
Klionsky, D. J., Abdel-Aziz, A. K., Abdelfatah, S., Abdellatif, M., Abdoli, A., Abel, S., Abeliovich, H., Abildgaard, M. H., Abudu, Y. P., Acevedo-Arozena, A., et al. (2021) · Autophagy · doi:10.1080/15548627.2020.1797280 · Cited by 2,897
Regulation and function of the cGAS–STING pathway of cytosolic DNA sensing
Chen, Q., Sun, L., & Chen, Z. J. (2016) · Nature Immunology · doi:10.1038/ni.3558 · Cited by 2,333
The cGAS–STING pathway as a therapeutic target in inflammatory diseases
Decout, A., Katz, J. D., Venkatraman, S., & Ablasser, A. (2021) · Nature Reviews Immunology · doi:10.1038/s41577-021-00524-z · Cited by 2,309
Molecular mechanisms and cellular functions of cGAS–STING signalling
Hopfner, K.-P., & Hornung, V. (2020) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-020-0244-x · Cited by 2,052
Metadata
- Authors
- Konno, H., Konno, K., & Barber, G. N.
- Venue
- Cell
- Publisher
- Elsevier BV
- Published
- 2013-10
- Volume
- 155
- Issue
- 3
- Pages
- 688-698
- ISSN
- 0092-8674
- PMC
- PMC3881181
- Cited by
- 687
- References
- 7
- Language
- en
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review